Clinical trials: Child Malnutrition
Vitamin A Deficiency
The Efficacy of Pro-vitamin A Biofortified Cassava on Vitamin A Status in Nigerian Preschool Children
The study comprises an open-label randomized controlled trial investigating the efficacy of consuming a daily ration of pro-vitamin A biofortified cassava on vitamin A status of Nigerian children, aged 3-4 years old (n=200).
- Trial name
- CASSAVITA II (NCT02627222)
- Testing
- Pro-vitamin A biofortified cassava, White cassava
- Where
- Nigeria
- Volunteers
- 176 people, healthy volunteers welcome
- Sponsor
- Wageningen University
Acute Malnutrition in Childhood, Wasting
Simplified Treatment Protocol for Acute Malnutrition in Venezuela
Global acute malnutrition (GAM) in children under five is defined by being too thin for a given height and/or having the Mid-upper arm circumference less than a given threshold.
- Conditions
- Acute Malnutrition in Childhood, Wasting, Child Malnutrition
- Trial name
- NCT05543759
- Testing
- Ready-To-Use Therapeutic Food (RUTF)
- Where
- Venezuela
- Volunteers
- 307 people
- Sponsor
- UNICEF - Venezuela
Pediatric Cancer, Nutrition Related Cancer
Pediatric Oncology Nutrition Intervention Trial
Nearly 60% of pediatric patients diagnosed with cancer develop malnutrition caused by a combination of disease burden, side effects of chemotherapy, and the intensity of cancer treatment.
- Conditions
- Pediatric Cancer, Nutrition Related Cancer, Nutrition Aspect of Cancer, Muscle Loss
- Trial name
- POINT (NCT06175273)
- Testing
- Oral Nutrition Supplement, Tube Feed, Cyproheptadine
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Corey Hawes
Diarrhea, Wasting
Lactoferrin and Lysozyme Supplementation for Long-term Diarrhea Sequelae
Children in low- and middle-income countries who are hospitalized for diarrhea and also have malnutrition are at high risk for illness and death in the 6 months period following treatment for diarrhoea despite receiving current…
- Conditions
- Diarrhea, Wasting, Malnutrition, Child
- Trial name
- NCT05519254
- Testing
- Lactoferrin, Lysozyme, Lactoferrin + Lysozyme
- Where
- 4 sites in Kenya
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- University of Washington
Growth Retardation, Malnutrition
Nutrition Education Package for Infants and Young Child Feeding and Health in Rural Tanzania
Building on the success of community-based peer education and counselling in breastfeeding, it is possible to address young child feeding and health practices in the surveyed district.
- Trial name
- NECTAc (NCT02249754)
- Testing
- Nutrition education, Routine health education
- Where
- Tanzania
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Sokoine University of Agriculture
Malnutrition, Child, Severe Acute Malnutrition
Azithromycin as Adjunctive Treatment for Uncomplicated Severe Acute Malnutrition
Amoxicillin is recommended by the World Health Organization (WHO) as adjunctive therapy for the treatment of uncomplicated severe acute malnutrition (SAM).
- Trial name
- AMOUR (NCT06010719)
- Testing
- Azithromycin, Amoxicillin
- Where
- Burkina Faso
- Volunteers
- 3,000 people
- Sponsor
- University of California, San Francisco
Micronutrient Deficiency
Comparison of Two Nutrition Interventions in Young Children in El Salvador
Adequate nutrition during the first years of life is essential to reach full body and brain development potential. Children under the age of 5 in Central America and El Salvador suffer from micronutrient deficiencies.
- Trial name
- NCT02567981
- Testing
- 21 micronutrient-fortified supplement, Cereal Fortificado (Fortified Cereal), Ferrous sulphate
- Where
- El Salvador
- Volunteers
- 4,577 people, healthy volunteers welcome
- Sponsor
- The Mathile Institute for the Advancement of Human Nutrition
Malnutrition in Children
Women Supporting Women to Improve Infant and Child Feeding Practices in Pakistan
This project aims to reduce child malnutrition in Pakistan by building on local strengths and practical community solutions. The project focuses on children 7-23 months of age.
- Trial name
- NCT07345754
- Testing
- 28-day Behavioural Change Program
- Where
- Pakistan
- Volunteers
- 200 people
- Sponsor
- University of British Columbia
Malnutrition
Evaluation of Two Community Based Screening Strategies for Severe Acute Malnutrition in Children 6-59 Months in Mirria District, Niger
The objective of this study is to determine the efficacity of a community strategy for screening children 06-59 months old for Severe Acute Malnutrition (SAM) conducted by their mothers' compared with a community screening…
- Trial name
- MàLÉ (NCT01863394)
- Testing
- Screening by mothers, Active comparator: Screening by community health workers
- Where
- Niger
- Volunteers
- 4,429 people
- Sponsor
- Alliance for International Medical Action
Epilepsy, Vitamin D Deficiency
Vitamin D Supplementation to Prevent Vitamin D Deficiency for Children With Epilepsy
To determine the maintenance dose of vitamin D supplementation required for children with epilepsy to maintain normal vitamin D level.
- Trial name
- NCT03536845
- Testing
- Vitamin D 3
- Where
- Saudi Arabia
- Volunteers
- 116 people
- Sponsor
- King Saud University
Vitamin D Deficiency, 25-Hydroxyvitamin D3 Deficiency, Selective
Effect of Vitamin D3 Supplementation in Children From 12 to 30 Months of Age.
Background Vitamin D (VD) is essential for calcium absorption, bone health and growth in children. In a national representative sample authors found mean serum concentration of 25-Hydroxi-Vitamin-D (25-OH-D) of 59 nmol/L, in…
- Trial name
- NCT03544671
- Testing
- Vitamin D
- Where
- Mexico
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Instituto Nacional de Salud Publica, Mexico
Malnutrition
Effectiveness of Child Centered Counseling on Child Nutrition Status
Hypothesis N°1: The "children growth promotion based on approach centered on their specific needs" enhances caretakers and health workers skills, knowledge and practices on breastfeeding, complementary feeding and child care.
- Trial name
- LUCOMAI (NCT01977365)
- Testing
- Growth promotion based on child centered approach
- Where
- Burkina Faso
- Volunteers
- 2,341 people, healthy volunteers welcome
- Sponsor
- Institut de Recherche en Sciences de la Sante, Burkina Faso
Malnutrition, Child, Cognitive Function
Locally Prepared Supplement to Support Growth and Brain Health
This study is a randomized controlled trial with a main goal to assess the effects of a locally-prepared food for prevention of malnutrition and stunting, in comparison with standard village practices and also a widely available…
- Trial name
- NCT03017209
- Testing
- Locally-prepared bar, USAID Corn Soy Blend Plus
- Where
- Guinea-Bissau
- Volunteers
- 1,059 people, healthy volunteers welcome
- Sponsor
- Tufts University
Kwashiorkor, Marasmus
Effectiveness of Oral Antibiotics in the Treatment of Severe Acute Malnutrition
The need for oral antibiotics as part of the case management of severe acute malnutrition (SAM) in the outpatient setting has not been studied in a prospective trial.
- Trial name
- NCT01000298
- Testing
- Amoxicillin, Cefdinir
- Where
- Malawi
- Volunteers
- 2,767 people
- Sponsor
- Washington University School of Medicine
Moderate Acute Malnutrition
Treating Moderate Malnutrition in 6-24 Months Old Children
Child malnutrition is intimately associated to poverty and may be due to sub-optimal feeding behaviours, food insecurity at household level, or a combination of both.
- Trial name
- LUCOMA (NCT01115647)
- Testing
- Ready-to-Use Therapeutic Food (RUTF), CBS++, CCC
- Where
- Burkina Faso
- Volunteers
- 2,088 people
- Sponsor
- Institute of Tropical Medicine, Belgium
Malnutrition, Child
Effect of an Alternative RUTF on Intestinal Permeability in Children With Severe Acute Malnutrition
Ready-to-use therapeutic food (RUTF) is the standard of care for the treatment of SAM. UNICEF requires that there be no oil separation in these products necessitating the use of emulsifiers.
- Trial name
- NCT04334538
- Testing
- S-RUTF, oat RUTF
- Where
- Sierra Leone
- Volunteers
- 129 people
- Sponsor
- Washington University School of Medicine
Congenital Heart Disease in Children, Post-cardiac Surgery
To Assess the Efficacy of Early Administration of Energy Enriched and Protein Enriched Formula in Post Cardiac Repair Infants: a Randomized Controlled Trial, Comparative Study
Congenital heart disease (CHD) is a public health problem, A substantial percentage of infants and toddlers with CHD undergo cardiopulmonary bypass surgery.
- Conditions
- Congenital Heart Disease in Children, Post-cardiac Surgery, Malnutrition, Infant
- Trial name
- NCT05826769
- Testing
- Energy- Protein Enriched Nutritional Formula
- Where
- Saudi Arabia
- Volunteers
- 60 people
- Sponsor
- King Faisal Specialist Hospital & Research Center
Malnutrition, Malaria
Effectiveness of Nutritional Supplementation in Preventing Malnutrition in Children With Infection
The purpose of this study is to determine whether 14 days nutritional supplementation with Ready to use therapeutic Food (RUTF) or micronutrients alone to children having an infection will prevent malnutrition and reduce the…
- Conditions
- Malnutrition, Malaria, Lower Respiratory Tract Infection, Diarrhoea
- Trial name
- NCT01154803
- Testing
- Ready to Use Therapeutic Food (RUTF), Micronutrient Powder (MNP)
- Where
- Nigeria
- Volunteers
- 2,213 people
- Sponsor
- Medecins Sans Frontieres, Netherlands
Child Malnutrition
Acceptability of a Multiple Micronutrient-Fortified Lipid-Based Nutrient Supplement for Children Under Two in Cambodia
The purpose of this trial is to evaluate the acceptability of the LNS to women and their children aged 12-17 months in comparison to Corn Soy Blend++, and Sprinkles added to borbor (white rice porridge, which is the traditional…
- Trial name
- NCT02257437
- Testing
- LNS snack, Corn-soy blend ++ (CSB++), Sprinkles
- Where
- Cambodia
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Institut de Recherche pour le Developpement, Cambodia
Malnutrition, Infant, Malnutrition; Anemia
Bhaktapur Maternal and Child Micronutrient Study
Between February 2008 and February 2009, 500 infant-mother pairs in Bhaktapur, Nepal were randomly selected in this nutritional survey.
- Trial name
- NCT03285399
- Where
- Nepal
- Volunteers
- 1,000 people
- Sponsor
- Centre For International Health