Clinical trials: Child Malnutrition
Child Acute Malnutrition
The Effect of Integrated Prevention and Treatment on Child Malnutrition and Health in Mali: a Cluster Randomized Intervention Study
Globally, child undernutrition is the underlying cause for 3.1 million deaths of children younger than 5 years. 18.7 million children under five years of age suffer from severe acute malnutrition (SAM) and an additional 33…
- Trial name
- PROMIS-Mali (NCT02323815)
- Testing
- Small-Quantity Lipid-based nutrient supplement, Child's health and nutrition topics
- Where
- Mali
- Volunteers
- 2,304 people, healthy volunteers welcome
- Sponsor
- International Food Policy Research Institute
Child Nutrition Disorders
A Nutrition/Hygiene Education Program for the Prevention of Child Malnutrition in Rural Kenya
This study will determine if an education program about hygiene and child feeding practices, taught by local village community health workers, will improve child growth and decrease the prevalence of childhood malnutrition in a…
- Trial name
- NCT01679535
- Testing
- nutrition and hygiene education
- Where
- United States
- Volunteers
- 246 people, healthy volunteers welcome
- Sponsor
- University of New Mexico
Arrest of Bone Development or Growth, Constitutional Delay of Growth and Puberty
YoUng Adolescents' behaViour, musculoskeletAl heAlth, Growth & Nutrition
More children will survive to adulthood today than at any other point in human history, as evidenced by the proportion of live births and absolute numbers.
- Conditions
- Arrest of Bone Development or Growth, Constitutional Delay of Growth and Puberty, Malnutrition, Child, Gestational Diabetes
- Trial name
- YUVAAN (NCT05603793)
- Testing
- Knowledge, Attitude & Practices
- Where
- India
- Volunteers
- 1,304 people, healthy volunteers welcome
- Sponsor
- Hirabai Cowasji Jehangir Medical Research Institute
Child Malnutrition
An Intervention for Primary Caregivers to Improve Outcomes in Children With Severe Malnutrition
This cluster-randomized controlled trial will evaluate the effectiveness of a four-day hospital-based intervention program for primary caregivers of children with severe malnutrition.
- Trial name
- NCT03072433
- Testing
- Counseling Intervention Package, Standard of Care
- Where
- Malawi
- Volunteers
- 181 people
- Sponsor
- The Hospital for Sick Children
Moderate Acute Malnutrition
Acceptability and Efficacy of 'Fish Surimi Peptide' in Under Five Children Suffering From Moderate Acute Malnutrition
Protein-energy malnutrition (PEM) including moderate acute malnutrition (MAM: weight-for-height z-score <-2 to -3, or mid upper arm circumference (MUAC) 115 to < 125 mm) is a major cause of morbidity and mortality in under-5…
- Trial name
- NCT02272543
- Testing
- Fish surimi peptide
- Where
- Bangladesh
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- International Centre for Diarrhoeal Disease Research, Bangladesh
Hypophosphatemic Rickets, Growth Disorders
Effects of GH on Body Proportions and Final Height in X-Linked Hypophosphatemic Rickets
X-linked hypophosphatemic rickets (XLH) is characterized by rickets, disproportionate short stature, impaired renal phosphate reabsorption and vitamin D metabolism.
- Conditions
- Hypophosphatemic Rickets, Growth Disorders, Somatropin Therapy
- Trial name
- NCT00473187
- Testing
- somatropin
- Where
- Germany
- Sponsor
- University of Rostock
Acute Malnutrition, Severe, Malnutrition, Child
Increasing the Coverage of Severe Acute Malnutrition (SAM) Treatment in Ethiopia
The R-SWITCH intervention aims to address the low coverage of treatment for severe wasting (SAM) by leveraging existing community groups to deliver an integrated package focused on prevention, screening, referral, and treatment…
- Conditions
- Acute Malnutrition, Severe, Malnutrition, Child, Wasting
- Trial name
- R-SWITCH (NCT06380504)
- Testing
- R-SWITCH integrated intervention package
- Where
- Ethiopia
- Volunteers
- 1,080 people, healthy volunteers welcome
- Sponsor
- International Food Policy Research Institute
Type 2 Diabetes, Vitamin D Deficiency
African American Children, Glycemic Control, and Type 2 Diabetes
Using a randomized, placebo-controlled trial design in subjects with vitamin D deficiency, the investigators propose to determine if vitamin D treatment improves glycemic control in vitamin D deficient subjects with T2DM.
- Trial name
- ACT (NCT01325987)
- Testing
- Vitamin D2, Sugar pill
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- University of Alabama at Birmingham
Rare Diseases, X-linked Hypophosphatemia
Burosumab in Children and Adolescents With X-linked Hypophosphatemia
In this prospective longitudinal cohort study we studied the efficacy and safety of burosumab in real-clinical practice for <13- and >13-years old children affected with X-linked hypophosphatemia.
- Trial name
- NCT04419363
- Testing
- Burosumab Injection
- Where
- France
- Volunteers
- 57 people
- Sponsor
- Bicetre Hospital
Alkaline Phosphatase Deficiency, Vitamin D Deficiency
Serum Alkaline Phosphatase Levels In Healthy Turkish Children
Alkaline phosphatase (ALP), is a metalloenzyme of the plasma membrane. Serum ALP levels in children are closely related to age and gender, many commercial test kits being used in hospitals, are only offering reference values for…
- Trial name
- NCT06689709
- Testing
- Serum Alkaline Phosphatase Levels
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Emine Hafize
Microbiota, Complementary Food
Community-based Clinical Trial With Microbiota-directed Complementary Foods (MDCFs) Made of Locally Available Food Ingredients for the Management of Children With Primary Moderate Acute Malnutrition
Background (brief): Burden: A total of 52 million children under 5 are suffering from acute malnutrition globally, of whom 33 million have moderate acute malnutrition (MAM).
- Conditions
- Microbiota, Complementary Food, Nutrition
- Trial name
- NCT04015999
- Testing
- Microbiota Directed Complementary Food (MDCF), Ready to Use Supplementary Food (RUSF)
- Where
- Bangladesh
- Volunteers
- 124 people
- Sponsor
- International Centre for Diarrhoeal Disease Research, Bangladesh
Environmental Enteric Dysfunction, Stunting
Maternal Probiotic Intervention to Improve Gut Health
There is an urgent need to identify interventions that can improve the supportive uterine environment in which the fetus establishes his/her growth.
- Trial name
- MPIGH (NCT05922683)
- Testing
- Vivomixx, CapScan®
- Where
- Pakistan
- Volunteers
- 76 people
- Sponsor
- Aga Khan University
Nutrition Poor, Health Behavior
Virtual Technical Assistance for Child and Adult Care Food Program in Family Child Care Home
This study evaluates the effect of a fully virtual nutrition technical assistance training program for family child care home providers on the food they serve young children in their care and the food environment in their home.
- Trial name
- NCT04345874
- Testing
- Nutrition technical assistance, Children's environmental health technical assistance
- Where
- United States
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- University of Oklahoma
Acute Malnutrition in Childhood, Wasting
Integrated Research on Acute Malnutrition in Mali (IRAM-MALI)
The IRAM MALI impact evaluation uses a cluster-randomized controlled study design to assess the impact of the package of integrated interventions aimed at reducing the longitudinal prevalence of wasting by reducing the incidence…
- Trial name
- NCT04872088
- Testing
- Strengthened SBCC, Preventive nutritional supplement, Family MUAC
- Where
- Mali
- Volunteers
- 9,797 people
- Sponsor
- International Food Policy Research Institute
Child Nutrition Disorders, Malnutrition
Community Based Management of Severe Malnutrition in Tribal Area of Melghat- Cluster Randomized Control Field Trial
Provision of community based health care to severely malnourished children (Age group: 6 months through 5 years) in 16 tribal villages by trained semi-literate village health workers. 1.
- Trial name
- SAMMAN (NCT02671786)
- Testing
- MAHAN RUTF & MAHAN Vit-Min mix
- Where
- India
- Volunteers
- 824 people
- Sponsor
- MAHAN Trust
Cardiovascular Diseases, Diabetes Mellitus, Type 2
Healthy Lifestyle Promotion Program in Communities From the Yaqui Valley
The aim is to evaluate the change in indicators of lifestyle and its effect on cardiometabolic biomarkers as a response to an integrative mother-child intervention to promote healthy lifestyles and prevent food insecurity and…
- Trial name
- NUTRIGANDO (NCT05945862)
- Testing
- NUTRIGANDO
- Where
- Mexico
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Instituto Tecnologico de Sonora
Appetite Loss
Effectiveness of Cyproheptadine Hydrochloride Against Appetite to Improve Children's Nutritional Status
The goal of this clinical trial is to learn about the benefits of Cyproheptadine hydrochloride in increasing appetite as well as its effect on weight gain in children aged 1-5 years who have difficulty eating.
- Trial name
- NCT07006181
- Testing
- cyproheptadine hydrochloride
- Where
- Indonesia
- Volunteers
- 44 people
- Sponsor
- Universitas Indonesia
Malnutrition, Child
Assessment of Starch Digestibility and Amylase Sufficiency in Children
Research has demonstrated that there is a relationship between malnourishment and insufficient production of pancreatic enzymes, such as α-amylase which digests starch into glucose.
- Trial name
- NCT03467737
- Testing
- Normal sorghum porridge, algal starch, Normal sorghum porridge, algal dextrins, Normal sorghum porridge, labeled flour
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Purdue University
Protein-energy Malnutrition, Kwashiorkor
Study of Antioxidants and Oxidants in Malnourished Children
It is believed that the organs of severely malnourished children malfunction because harmful compounds called oxidants injure the tissues in these organs.
- Conditions
- Protein-energy Malnutrition, Kwashiorkor, Marasmus
- Trial name
- NCT00069134
- Testing
- sulfur amino acids
- Where
- Jamaica
- Volunteers
- 86 people
- Sponsor
- Baylor College of Medicine
Refeeding Syndrome
Prevention of Refeeding Syndrome
To determine effects of different caloric density intake in prevention of refeeding syndrome in critically ill children
- Trial name
- NCT06589479
- Volunteers
- 50 people
- Sponsor
- Assiut University