Clinical trials: Child Malnutrition
Undernutrition, Wasting
Evaluating Oral Nutritional Supplements on Children's Nutritional Status and Digestive Health in Vietnam.
Evaluating the efficiency of using Oral Nutritional Supplementation toward nutrition status (anthropometric index, the prevalence of wasting), digestive disorders, and anorexic in children aged 24 - 71 months.
- Conditions
- Undernutrition, Wasting, Malnourished
- Trial name
- NCT05551637
- Testing
- Kazu Gain Gold
- Where
- Vietnam
- Volunteers
- 600 people
- Sponsor
- Tu Nguyen Song
Severe Acute Malnutrition, Kwashiorkor
Effectiveness of Alternative Diets During the Stabilization Phase on Children With Complicated SAM
Severe acute malnutrition (SAM) is a life threatening condition and is defined by 1) a weight-for-height Z-score more than three standard deviations (SD) below the median based on the 2006 World Health Organization (WHO) growth…
- Conditions
- Severe Acute Malnutrition, Kwashiorkor, Nutritional Edema, Marasmus
- Trial name
- NCT05020847
- Testing
- Standard F75, Alternative F75 with CMV, Alternative F75 without CMV
- Where
- Burkina Faso
- Volunteers
- 297 people
- Sponsor
- University Ghent
Water-Related Diseases
SAFEWATER Health & Behaviour Impact Field Trials; Mexico
At least 1.8 billion people globally use a source of drinking water that is faecally contaminated and thus likely to lead to diarrheal illness: nearly 1,000 children die each day due to water and sanitation-related diarrhoeal…
- Trial name
- NCT04736615
- Testing
- SAFEWATER systems for drinking water disinfection, Behavior change interventions
- Where
- 3 sites in Colombia, Mexico
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Ulster
Asthma, Vitamin D Deficiency
Rapid vs Maintenance Vitamin D Supplementation in Deficient Children With Asthma to Prevent Exacerbations.
The role of vitamin D in respiratory health remains uncertain. Whether vitamin D reduces clinically important exacerbations of childhood asthma remains uncertain.
- Trial name
- NCT01395589
- Testing
- Vitamin D
- Where
- Qatar
- Volunteers
- 597 people, healthy volunteers welcome
- Sponsor
- Hamad Medical Corporation
Paediatric Oncology, Malnutrition in Children
Development of a Digital Personalised Nutrition Tool for Adolescents Undergoing Cancer Treatment
This study aims to develop and test MybYte, a smartphone tool designed to support personalised nutrition for teenagers aged 12-18 undergoing cancer treatment.
- Trial name
- MybYte (NCT07865117)
- Testing
- The MybYte tool, a digital personalised nutrition tool for adolescents undergoing cancer treatment
- Where
- Belgium
- Volunteers
- 30 people
- Sponsor
- KU Leuven
Malnutrition Severe, Vaccination
OptiMAx Will Test Whether SQ-LNS Incentivises Vaccination Uptake in Rural Chad and Niger, With a Cost Effectiveness Analysis. It Will Also Look at Whether Having Received SQ-LNS Before Becoming Malnourished Leads to Better Outcomes for Children Treated Under the OptiMA Protocol.
Malnutrition and infectious disease form a vicious circle, posing a double threat to vulnerable children in low- and middle-income countries.
- Trial name
- OptiMAx (NCT07592260)
- Testing
- small quantity lipid-based supplement (SQ-LNS)
- Where
- 2 sites in Chad, Niger
- Volunteers
- 20,000 people, healthy volunteers welcome
- Sponsor
- Alliance for International Medical Action
Poor Nutrition
Acceptability and Tolerance of a Protein and Micronutrient Fortified Food
Acceptability and tolerance of a new food product in adults and children.
- Trial name
- NCT03041103
- Testing
- Food Product 1
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
X-Linked Hypophosphatemia
Study of the Safety, Pharmacodynamics (PD) and Efficacy of KRN23 in Children From 1 to 4 Years Old With X-linked Hypophosphatemia (XLH)
The primary objectives of the study are to: Establish the safety profile of KRN23 for the treatment of XLH in children between 1 and 4 years old Determine the PD effects of KRN23 treatment on serum phosphorus and other PD markers…
- Trial name
- NCT02750618
- Testing
- Burosumab
- Where
- 3 sites in United States
- Volunteers
- 13 people
- Sponsor
- Kyowa Kirin, Inc.
Nutritional Rickets, Bone Turnover Rate Disorder
Effectiveness of Vitamin C Supplementation in Treatment of Rickets
Effectiveness of therapeutic dose of vitamin C in infants and children with nutritional rickets as an adjuvant therapy with vitamin D and calcium The study is two armed Randomized Control Trial, to validate the role of Vit C…
- Trial name
- NCT05310760
- Testing
- Vit C
- Where
- Egypt
- Volunteers
- 88 people
- Sponsor
- Cairo University
Malnourishment
Cognitive Effects of Omega-3 Supplements in Children With Mild to Moderate Malnutrition
Adequate nutrition is one of the critical biological processes to learning and cognitive development of children. And is understandable that malnourishment affect these processes.
- Trial name
- NCT01199120
- Testing
- Omega 3
- Where
- Mexico
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Universidad Autonoma de Ciudad Juarez
Vitamin D Deficiency, Dental Caries
Maternal Vitamin D Levels in Pregnancy and Dental Caries in Children
The main aim of this study is to investigate potential associations between maternal pre- and postnatal vitamin D level and oral health outcomes (caries and developmental defects of enamel) in their children at 7-9 years of age.
- Conditions
- Vitamin D Deficiency, Dental Caries, Dental Enamel Hypoplasia
- Trial name
- NCT03273725
- Testing
- Dental examination including taking a saliva sample.
- Volunteers
- 178 people, healthy volunteers welcome
- Sponsor
- Tannhelsetjenestens Kompetansesenter Midt-Norge
Moderate Acute Malnutrition
Comparing Several Strategies to Manage Moderate Acute Malnutrition Among Children From 6 to 24 Months Old
The aim of this open-label randomized controlled trial conducted in four African countries (Madagascar, Niger, Central African Republic and Senegal) is to compare three strategies of renutrition for moderate acute malnutrition…
- Trial name
- MALINEA (NCT03474276)
- Testing
- Azythromycin, Inuline and fructo-oligosaccharides, Albendazole
- Where
- 4 sites in Central African Republic, Madagascar and 2 more
- Volunteers
- 1,357 people, healthy volunteers welcome
- Sponsor
- Institut Pasteur
Severe Acute Malnutrition
Therapeutic Approaches to Malnutrition Enteropathy
The TAME study will evaluate four new approaches which will be compared against the standard care currently in use in the treatment of malnutrition enteropathy in children with severe acute malnutrition.
- Trial name
- TAME (NCT03716115)
- Testing
- Colostrum high protein powder (Neovite), N-Acetyl Glucosamine (GInNAC), Teduglutide
- Where
- 3 sites in Zambia, Zimbabwe
- Volunteers
- 125 people
- Sponsor
- Queen Mary University of London
Severe Acute Malnutrition
RECIPE BASED F100 INTERVENTION FOR NUTRITIONAL EFFICACY IN SAM (REFINE-SAM )
This open-label randomized controlled trial evaluates the efficacy and safety of multiple formulations of the F-100 therapeutic feed during the rehabilitation phase among children aged 6-59 months with SAM, in comparison to…
- Trial name
- REFINE-SAM (NCT07130877)
- Testing
- WHO F100, WHO RECIPE BASED F100
- Where
- 2 sites in Pakistan
- Volunteers
- 114 people
- Sponsor
- Children's Hospital and Institute of Child Health, Multan
Child Malnutrition
Use of a 10 Points Visual Analogue Food Intake Scale for Children to Assess Intake: Prospective Study
In hospitalized children, undernutrition increases the length of hospitalization, aggravates the causal pathology, favors the occurrence of complications, and increases the cost of hospitalization.
- Trial name
- CESAR (NCT05726422)
- Where
- France
- Volunteers
- 102 people
- Sponsor
- University Hospital, Montpellier
Vitamin B 12 Deficiency
Cobalamin Status in Young Children With Developmental Delay
During fetal life and infancy, an adequate cobalamin status is important for normal growth and central nervous system development.
- Trial name
- NCT00710138
- Testing
- Hydroxycobalamin (Vitamin B12 Depot, Nycomed Pharma)
- Where
- Norway
- Volunteers
- 100 people
- Sponsor
- Haukeland University Hospital
Child Malnutrition
Strategies to Increase Milk Consumption by Young Nepali Children
Dairy animals are an important source of income, food and nutrition security at the household level. However, substandard animal husbandry practices and limited understanding of disease prevention and control may limit dairy…
- Trial name
- NCT03886467
- Testing
- Community-based nutrition education
- Where
- Nepal
- Volunteers
- 368 people
- Sponsor
- Tufts University
Vitamin A Deficiency, Iron-deficiency
Effect of Household Use of Multiple Micronutrient-fortified Bouillon on Micronutrient Status Among Women and Children in Two Districts in the Northern Region of Ghana
Background: Micronutrient (MN) deficiencies are severe and widespread in West Africa, particularly among young children and women of reproductive age.
- Conditions
- Vitamin A Deficiency, Iron-deficiency, Folate Deficiency, Vitamin B 12 Deficiency
- Trial name
- NCT05178407
- Testing
- Multiple micronutrient-fortified bouillon cube, Control bouillon cube (iodine-only)
- Where
- Ghana
- Volunteers
- 2,372 people
- Sponsor
- University of California, Davis
Severe Acute Malnutrition, Kwashiorkor
Effectiveness of Four Transition Dietary Regimens in the Hospital Management of Children With Kwashiorkor.
In Burkina Faso the number of severely acute malnourished (SAM) children successfully treated has increased since the implementation of community-based management of acute malnutrition.
- Conditions
- Severe Acute Malnutrition, Kwashiorkor, Nutritional Edema
- Trial name
- NCT05015257
- Testing
- Standard F100, Standard F75 + Plumpynut, Alternative F75 with CMV + Plumpynut
- Where
- Burkina Faso
- Volunteers
- 32 people
- Sponsor
- University Ghent
Severe Acute Malnutrition, Health Care Associated Infection
Prevention of Nosocomial Infections (CleanKids)
While the standardization of treatment protocols for Severe Acute Malnutrition (SAM) has helped to reduce historically high mortality, mortality in inpatient settings remains substantial, likely due to the severity of…
- Conditions
- Severe Acute Malnutrition, Health Care Associated Infection, Multi Drug Resistant Organisms
- Trial name
- CleanKids (NCT03360877)
- Testing
- Health-care associated infection (HCAI)
- Volunteers
- 4,944 people
- Sponsor
- Epicentre