Clinical trials: Child Malnutrition
Severe Acute Malnutrition in Childhood, Pneumococcal Disease
Opportunistic Pneumococcal Immunisation Trial in MALnutrition
The goal of the OPTIMAL clinical trial is to learn if a dose of a pneumococcal conjugate vaccine (PCV) generates a good immune response in young children who are in hospital with severe acute malnutrition.
- Conditions
- Severe Acute Malnutrition in Childhood, Pneumococcal Disease, Pneumococcal Vaccines, Pneumococcal Infection
- Trial name
- OPTIMAL (NCT06817421)
- Testing
- Pneumococcal conjugate vaccine, Typhoid conjugate vaccine
- Where
- Timor-Leste
- Volunteers
- 214 people
- Sponsor
- Nick Fancourt
Vitamin D Deficiency, Orthostatic Intolerance
Vitamin D Deficiency and Dysautonomia
In previous work the investigator identified a group of children between the ages of 10-18 years whose diagnostic workup for chronic nausea unexplained by conventional diagnostic tests has unexpectedly revealed underlying…
- Conditions
- Vitamin D Deficiency, Orthostatic Intolerance, Nausea
- Trial name
- NCT03032328
- Testing
- vitamin D supplement
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Tuberculosis, Severe Acute Malnutrition
Development of a Diagnostic Prediction Score for Tuberculosis in Hospitalized Children With Severe Acute Malnutrition (TB-Speed SAM)
TB-Speed SAM is a multicentric, prospective diagnostic cohort study conducted in two countries with high and very high TB incidence (Uganda and Zambia).
- Trial name
- NCT04240990
- Testing
- Development of a score and algorithm for TB treatment decision in hospitalised children with SAM.
- Where
- 3 sites in Uganda, Zambia
- Volunteers
- 603 people
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Obesity, Pediatric, Obesity, Childhood
Efficacy of Vitamin D Supplementation in Obese Children
Vitamin D deficiency is common in the general population in the United States, but is more common in overweight and obese children.
- Conditions
- Obesity, Pediatric, Obesity, Childhood, Obesity, Morbid, Vitamin D Deficiency
- Trial name
- NCT02956408
- Testing
- Vitamin D3
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Columbia University
Pneumonia, Vitamin D Deficiency
Kabul Vitamin D Supplementation Trial
Background: Pneumonia is the leading cause of childhood mortality, accounting for 19% of the 10.6 million deaths that occur each year1.
- Trial name
- NCT00548379
- Testing
- vitamin D
- Where
- 2 sites in Afghanistan
- Volunteers
- 3,048 people, healthy volunteers welcome
- Sponsor
- London School of Hygiene and Tropical Medicine
Malnutrition, Child
Use of Low-level Laser Therapy on Children Aged One to Five Years With Energy-protein Malnutrition
Malnutrition is a clinical-social disease caused by multiple prenatal, intrauterine and postnatal factors as well as social, political and cultural determinants (distal causes).
- Trial name
- NCT03355313
- Testing
- Low level Light therapy
- Where
- 2 sites in Brazil
- Volunteers
- 50 people
- Sponsor
- University of Nove de Julho
Malnutrition in Children
Developmental Screening and Nutritional Intervention of Severe Acute Malnourished Children in Southern Punjab, Pakistan
i. To examine the impact of malnutrition on development quotient of children ii. To determine the effectiveness of Ready to Use Therapeutic Food (RUTF) in improving the development quotient of severe acute malnourished children…
- Trial name
- NCT03170479
- Testing
- Vitamin D, Ready to Use Therapeutic Food (RUTF)
- Volunteers
- 185 people
- Sponsor
- University of the Punjab
Micronutrient Deficiency, Malnutrition, Child
Dietary Intake, Health and Micronutrient Status in Haiti
The general objective of this project is to collect information on dietary intake and nutritional status of women and young children in Haiti, to inform the design and management of national and subnational micronutrient…
- Conditions
- Micronutrient Deficiency, Malnutrition, Child, Malnutrition, Chronic Disease
- Trial name
- NCT04034381
- Testing
- No intervention (descriptive survey only)
- Where
- Haiti
- Volunteers
- 143 people
- Sponsor
- University of California, Davis
Micronutrient Deficiency
Comparison of Two Nutrition Interventions in Young Children in El Salvador
Adequate nutrition during the first years of life is essential to reach full body and brain development potential. Children under the age of 5 in Central America and El Salvador suffer from micronutrient deficiencies.
- Trial name
- NCT02567981
- Testing
- 21 micronutrient-fortified supplement, Cereal Fortificado (Fortified Cereal), Ferrous sulphate
- Where
- El Salvador
- Volunteers
- 4,577 people, healthy volunteers welcome
- Sponsor
- The Mathile Institute for the Advancement of Human Nutrition
Poverty, Child Malnutrition
The Effect of a Cash Transfer Program and Preventive Nutrition Packages on Household Welfare and Child Nutritional Status in Mali
In the last two decades, cash transfer (CT) programs have emerged as a popular approach to long-term poverty alleviation. While the main goal of cash transfer programs is to reduce poverty, they also have the potential to improve…
- Trial name
- Jigisemejiri (NCT02858011)
- Testing
- Cash distribution during first 36 months, Accompanying information sessions on health, child nutrition, household economics and education during first 36 months, Preventive Nutrition Packages during last 12 months
- Where
- Mali
- Volunteers
- 4,320 people
- Sponsor
- International Food Policy Research Institute
Severe Malnutrition, Enteritis
Hypoallergenic and Anti-inflammatory Feeds in Malawian Children With Severe Acute Malnutrition (SAM)
Children with complicated severe acute malnutrition (SAM), such as inability to take adequate feeds, infection and diarrhoea, require in-patient management.
- Trial name
- SAM (NCT02639416)
- Testing
- Polymeric formula, Elemental formula, Standard management
- Where
- Malawi
- Volunteers
- 95 people
- Sponsor
- Liverpool School of Tropical Medicine
Vitamin A Deficiency
Efficacy of Yellow Cassava to Improve Vitamin A Status of Kenyan School Children
The overall aim of the project is to provide proof-of-principle that biofortification of cassava with vitamin A is a viable strategy to improve vitamin A status of deficient populations.
- Trial name
- CASSAVITA (NCT01614483)
- Testing
- Yellow cassava, White cassava
- Where
- Kenya
- Volunteers
- 341 people, healthy volunteers welcome
- Sponsor
- Wageningen University
Chronic Kidney Disease Mineral and Bone Disorder
Calcium Balance Studies in Children With CKD and on Dialysis
This is a novel, non-invasive method of assessing Ca balance by natural Ca isotope fractionation.
- Trial name
- Cal-Bal (NCT03285854)
- Testing
- Collection of blood, urine and stool samples
- Where
- United Kingdom
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Great Ormond Street Hospital for Children NHS Foundation Trust
Pneumonia Childhood
Effectiveness Trial of Day-care vs. Usual Care of Severe Pneumonia & Malnutrition in Children
Background: At present pneumonia and malnutrition have become the leading causes of mortality among <5-year-old children in developing countries.
- Trial name
- Day-care (NCT02669654)
- Testing
- Day-care management of Severe Pneumonia
- Where
- 2 sites in Bangladesh
- Volunteers
- 4,000 people
- Sponsor
- International Centre for Diarrhoeal Disease Research, Bangladesh
Malnutrition
Validation of the STAMP Screening Tool
Insufficient nutritional intake, with or without concomitant morbidity, leads to weight loss or insufficient weight gain, is related to an increase in morbidity and mortality and exposes the child to medical complications.
- Trial name
- STAMP2 (NCT01584310)
- Testing
- questionnaire STAMP and dietary, No STAMP using
- Volunteers
- 60 people
- Sponsor
- Rabin Medical Center
Acute Malnutrition in Childhood, Wasting
Simplified Treatment Protocol for Acute Malnutrition in Venezuela
Global acute malnutrition (GAM) in children under five is defined by being too thin for a given height and/or having the Mid-upper arm circumference less than a given threshold.
- Conditions
- Acute Malnutrition in Childhood, Wasting, Child Malnutrition
- Trial name
- NCT05543759
- Testing
- Ready-To-Use Therapeutic Food (RUTF)
- Where
- Venezuela
- Volunteers
- 307 people
- Sponsor
- UNICEF - Venezuela
HIV Disease, Vitamin D Deficiency
Vitamin D Supplementation in HIV-infected Youth
Along with its effects on bone metabolism, vitamin D is an important modulator of the immune system. Experimental studies have shown that the active metabolite of vitamin D [1,25(OH)2D] is able to skew the T cell compartment into…
- Conditions
- HIV Disease, Vitamin D Deficiency, Hypovitaminosis D, Hyperparathyroidism
- Trial name
- NCT01656070
- Testing
- oral cholecalciferol 1000000 UI (vitamin D3)
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- University of Milan
Congenital Heart Disease, Malnutrition
Preoperative Nutritional Intervention and Outcomes of Children Submitted to Heart Surgery for Congenital Heart Diseases
The hypothesis of this study is a nutrition preoperatively in infants and children undergoing elective cardiac surgery with cardiopulmonary bypass leads to improvement in nutritional status, intervention, and that this results in…
- Trial name
- NCT02647541
- Testing
- Nutritional intervention
- Where
- Brazil
- Volunteers
- 11 people
- Sponsor
- University of Sao Paulo
Wasting, Undernutrition
Improvement of Nutrition Status, Digestive Conditions, and Upper Respiratory Infections by Using Oral Nutritional Supplementation on Children in Vietnam
Evaluating the efficiency of using the nutrient production toward nutrition status (anthropometric index, the prevalence of wasting), digestive disorders, anorexia, and upper respiratory infections in children aged 24 - 71 months.
- Conditions
- Wasting, Undernutrition, Malnourished, Malnutrition
- Trial name
- NCT05570045
- Testing
- Colos Gain
- Where
- Vietnam
- Volunteers
- 600 people
- Sponsor
- Tu Nguyen Song
Malnutrition, Critical Illness
Assessment of Nutritional Status in Critically Ill Children in PICU
This prospective cohort study aims to assess the nutritional status of critically ill children aged 1 month to 5 years admitted to the pediatric intensive care unit using a comprehensive ABCD approach including anthropometric…
- Trial name
- NCT07830966
- Volunteers
- 103 people
- Sponsor
- Assiut University