Clinical trials: Child Malnutrition
Postoperative; Dysfunction Following Cardiac Surgery
Oral Triiodothyronine for Infants Less Than 5 Months & Malnourished Children Undergoing Cardiopulmonary Bypass in Indonesia
Infants and children undergoing cardiac surgery require mechanical support for circulation called cardiopulmonary bypass. The artificial pump ensures that blood flow to the body is maintained during surgical procedure on the…
- Trial name
- I-TRICC (NCT02222532)
- Testing
- Tetronine
- Where
- Indonesia
- Volunteers
- 224 people
- Sponsor
- National Cardiovascular Center Harapan Kita Hospital Indonesia
Vitamin D Deficiency
Vitamin D Supplementation in Children
Prevalence of vitamin D deficiency in children in the northern country during winter season is very high (up to 90%). Vitamin D supplementation at a dose 600 -1000 IU/d is recommended in Polish children from September till April.
- Trial name
- MeltD (NCT03402698)
- Testing
- cholecalciferol
- Where
- Poland
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- Children's Memorial Health Institute, Poland
Malnutrition
Evaluation of Two Community Based Screening Strategies for Severe Acute Malnutrition in Children 6-59 Months in Mirria District, Niger
The objective of this study is to determine the efficacity of a community strategy for screening children 06-59 months old for Severe Acute Malnutrition (SAM) conducted by their mothers' compared with a community screening…
- Trial name
- MàLÉ (NCT01863394)
- Testing
- Screening by mothers, Active comparator: Screening by community health workers
- Where
- Niger
- Volunteers
- 4,429 people
- Sponsor
- Alliance for International Medical Action
Cryptosporidiosis
Nitazoxanide for Treatment of Cryptosporidium in Children
The goal of this clinical trial is to learn if nitazoxanide (NTZ) can treat Cryptosporidium infection in children age 6-12 months.
- Trial name
- NCT06600711
- Testing
- Nitazoxanide
- Volunteers
- 480 people
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Acute Malnutrition in Childhood, Acute Malnutrition, Severe
Reduced Dosage and/or Visitation Protocol for the Treatment of Acute Malnutrition in Kenya
Severe acute malnutrition (SAM) places children at significant risk of mortality. Outpatient treatment programs are effective but there is a need to increase treatment coverage and reduce costs of treatment.
- Conditions
- Acute Malnutrition in Childhood, Acute Malnutrition, Severe, Acute Malnutrition, Moderate, Wasting
- Trial name
- RSWITCH (NCT07420062)
- Testing
- WHO-reduced, WHO-full, Kenya-IMAM
- Where
- Kenya
- Volunteers
- 2,274 people
- Sponsor
- International Food Policy Research Institute
Malnutrition
Trial to Alleviate Malnutrition With Fortified Spread Given as a Food Supplement to Underweight Infants
This study tests the hypothesis that underweight 6-17-month old infants receiving fortified spread as a food supplement for 12 weeks grow better during the supplementation than infants who are provided with maize-soy flour…
- Trial name
- NCT00131222
- Testing
- Food supplement: fortified spread, Food supplement: maize and soy flour
- Where
- Malawi
- Volunteers
- 176 people
- Sponsor
- Tampere University
Malaria, Severe Acute Malnutrition
Efficacy and Bio-availability of Artemether-Lumefantrine in Severely Malnourished Children
The general objective of the study is to answer to the question: "Is the current dose of AL less efficacious in the severely malnourished compared to the non-severely malnourished children, and is PK in cause?" We aim to assess…
- Trial name
- MAL-NUT (NCT01958905)
- Testing
- Artemether-lumefantrine fixed combination
- Where
- 2 sites in Mali, Niger
- Volunteers
- 399 people
- Sponsor
- Epicentre
Diarrhea, Dehydration
Zinc-ORS in Severe and Complicated Acute Diarrhea
Three-hundred-and-fifty-two males aged 1-36 months with acute non-dysenteric diarrhoea and no systemic illness will be enrolled in this clinical trial.
- Trial name
- NCT00370968
- Testing
- Zinc sulphate
- Where
- 2 sites in India
- Volunteers
- 352 people
- Sponsor
- Centre For International Health
Severe Acute Malnutrition, Cognitive Impairment
Milk Fat Globule Membrane-Enhanced RUTF for Children With Severe Acute Malnutrition
The goal of this clinical trial is to test the use of milk fat globule membrane (MFGM) in ready-to-use therapeutic food (RUTF) in children with severe acute malnutrition in Sierra Leone.
- Conditions
- Severe Acute Malnutrition, Cognitive Impairment, Kwashiorkor, Severe Wasting
- Trial name
- MEND-SAM (NCT06869850)
- Testing
- MFGM-RUTF (milk fat globule membrane ready-to-use therapeutic food), S-RUTF (standard ready-to-use therapeutic food), Amoxicillin
- Where
- 10 sites in Sierra Leone
- Volunteers
- 1,600 people
- Sponsor
- Washington University School of Medicine
Obesity, Childhood, Asthma in Children
Asthma and Obesity Diet Versus Exercise
Obesity is recognized as a pro-inflammatory condition associated with multiple chronic diseases, including asthma. The specific mechanisms linking asthma and obesity remain hypothetical.
- Conditions
- Obesity, Childhood, Asthma in Children, Inflammatory Response, Metabolic Syndrome
- Trial name
- NCT03644355
- Testing
- Lifestyle counseling
- Where
- United States
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Louisiana State University Health Sciences Center in New Orleans
Vitamin A Deficiency
Using Stable Isotope Techniques to Monitor and Assess the Vitamin A Status of Children Susceptible to Infection
The combination of infectious diseases and malnutrition is the most prevalent, preventable public health problem in the world, responsible for millions of deaths annually, particularly in infants and children.
- Trial name
- NCT02363985
- Testing
- Mega-dose of vitamin A supplement
- Where
- Ethiopia
- Volunteers
- 138 people, healthy volunteers welcome
- Sponsor
- Ethiopian Public Health Institute
Malnutrition
Whey Permeate Study
This is a prospective, randomized, double-blinded, controlled clinical effectiveness trial of two supplementary foods in the treatment of MAM.
- Trial name
- NCT01790048
- Testing
- Whey permeate RUSF, Soy Protein RUSF
- Where
- Malawi
- Volunteers
- 2,259 people
- Sponsor
- Washington University School of Medicine
Malnutrition, Child
The Effect of Continuous Egg Supplement on Personalized Nutri-omics in Primary School Children (SI-EGG STUDY)
This research compares the effects of one-year continuous whole egg supplement vs. egg yolk substitutes and control on anthropometry, biochemical blood parameters, metabolic enzymes and microbiome data in primary school children.
- Trial name
- NCT04896996
- Testing
- whole eggs, yolk-free egg substitutes
- Where
- Thailand
- Volunteers
- 635 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Diet Habit, Dietary Habits
Polish Infants and Toddler Nutritional Study
A cross-sectional study representative of the Polish population of children aged 5 months to 6 years conducted in the cross-sectional study model, the main objective of which is to assess the nutritional value of the diet of…
- Conditions
- Diet Habit, Dietary Habits, Diet, Healthy, Children
- Trial name
- PITNUTS (NCT06417151)
- Where
- Poland
- Volunteers
- 1,000 people
- Sponsor
- Fundacja Nutricia
Undernutrition, Underweight
Satiation Study With Children Attending a Tertiary Feeding Clinic
This is a pilot study of children attending the Glasgow feeding clinic (GFC) which looks after children with severe feeding problems who commonly have low appetite and extreme thinness.
- Trial name
- NCT04851327
- Testing
- High Energy preload, Low energy preload, Test meal
- Where
- United Kingdom
- Volunteers
- 17 people
- Sponsor
- University of Glasgow
Type 2 Diabetes, Nonalcoholic Fatty Liver Disease
Hepatic Dysfunction, Vitamin D Status, and Glycemic Control in Diabetes
This study is designed to study the effect of vitamin D intake on the severity of fatty liver and poor glucose control in patients with type 2 diabetes and fatty liver disease.
- Conditions
- Type 2 Diabetes, Nonalcoholic Fatty Liver Disease, Vitamin D Deficiency
- Trial name
- VDLS (NCT02132442)
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- University of Massachusetts, Worcester
Severe Acute Malnutrition, Persistent Diarrhea
Trial of Rice-Based F-75 in Severe Malnutrition & Persistent Diarrhea in Children (SAM-RICE Study)
The goal of this study is to find out if a rice-based version of the F-75 therapeutic food helps children with severe acute malnutrition (SAM) and persistent diarrhea recover better than the standard commercial F-75.
- Conditions
- Severe Acute Malnutrition, Persistent Diarrhea, Children
- Trial name
- SAM-RICE (NCT07070856)
- Testing
- WHO-recommended standard therapeutic milk used for stabilization phase in SAM), HO-recommended Rice based therapeutic milk used for stabilization phase in SAM)
- Where
- 2 sites in Pakistan
- Volunteers
- 320 people
- Sponsor
- Children's Hospital and Institute of Child Health, Multan
Severe Acute Malnutrition in Childhood, Malnutrition, Child
Treatment of Severe Acute Malnutrition in Children 6 to 59 Months Old With Standard Ready To Use Therapeutic Food Compared to a Newly Formulated Lipid Optimized Ready To Use Therapeutic Food
The goal of this randomized clinical trial is to learn if a newly formulated Lipid-Optimized Ready-to-Use Therapeutic Food (LO-RUTF) can treat severe acute malnutrition in children aged 6 to 59 months.
- Conditions
- Severe Acute Malnutrition in Childhood, Malnutrition, Child, Neurocognition, Child
- Trial name
- NCT07345884
- Testing
- Lipid-Optimized Ready to Use Therapeutic Food (RUTF), Ready to Use Therapeutic Food (RUTF)
- Where
- Pakistan
- Volunteers
- 125 people
- Sponsor
- University of California, Los Angeles
Nutritional Rickets
Vitamin D and Genetics in Nutritional Rickets
The purpose of this study is: 1. To compare the response of rickets to calcium with and without vitamin D. 2. To assess whether vitamin D increases calcium absorption in calcium deficiency rickets. 3.
- Trial name
- NCT00949832
- Testing
- Vitamin D + Calcium, Calcium, Vitamin D2
- Where
- Nigeria
- Volunteers
- 109 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Sickle Cell Disease, Malnutrition
Prevention of Malnutrition in Children With Sickle Cell Disease
The investigators are studying how to prevent malnutrition in children with sickle cell disease (SCD) in northern Nigeria. Community health workers will teach mothers about nutritious local foods that might help children grow…
- Trial name
- PMC-SCD (NCT06397118)
- Testing
- Maternal Nutrition Education, Standard Care
- Where
- United States
- Volunteers
- 146 people
- Sponsor
- Vanderbilt University Medical Center