Clinical trials: Child Mortality
Extracorporeal Membrane Oxygenation Complication, Hemorrhage
ECMO Hemostatic Transfusions in Children
Critically ill children supported by extracorporeal membrane oxygenation (ECMO) receive large volumes of prophylactic platelet transfusions to prevent bleeding.
- Conditions
- Extracorporeal Membrane Oxygenation Complication, Hemorrhage, Thromboembolism, Transfusion Adverse Reaction
- Trial name
- ECSTATIC (NCT05796557)
- Testing
- Platelet Transfusion
- Where
- 10 sites in United States, Israel
- Volunteers
- 50 people
- Sponsor
- Yale University
Mortality, Hospitalization
Randomized Study of Not Giving Diphteria-tetanus-pertussis Vaccination With or After Measles Vaccination
In non-randomized studies, routine childhood vaccinations have been observed to have non-targeted effects. Difteria-tetanus-pertussis (DTP) vaccine provided with or after measles vaccine (MV) is associated with increased…
- Conditions
- Mortality, Hospitalization, Adverse Events
- Trial name
- NCT00244673
- Testing
- DTP3/4+OPV+MV versus OPV+MV or DTP4+OPV4 versus OPV4
- Where
- Guinea-Bissau
- Volunteers
- 6,534 people
- Sponsor
- Bandim Health Project
Maternal and Child Health, Health Service Utilization
Integrated Community Based Health Systems Strengthening in Northern Togo
The general objective of this study is to optimize implementation and assess effectiveness of the integrated facility and community-based health systems strengthening (ICBHSS) model in four Northern Togo districts, using the…
- Trial name
- ICBHSS-Togo (NCT03694366)
- Testing
- ICBHSS model
- Where
- Togo
- Volunteers
- 7,600 people, healthy volunteers welcome
- Sponsor
- Integrate Health
Measles Vaccine
Trial of Additional Measles Vaccine to Reduce Child Mortality
Background: All observational studies and a few randomised controlled trials (RCT) suggest that early measles vaccine (MV), in particular an early two-dose strategy, has a much better effect on overall mortality than later MV.
- Trial name
- NCT01644721
- Testing
- Early measles vaccine
- Where
- Guinea-Bissau
- Volunteers
- 3,750 people
- Sponsor
- Bandim Health Project
Malaria
Early Childhood Malaria Prevention With Maloprim in The Gambia
A trial was conducted in the 1980s to compare two strategies for control of malaria in young children aged 3-59 months: treatment with chloroquine versus treatment combined with fortnightly chemoprophylaxis with Maloprim.
- Trial name
- NCT00294580
- Testing
- Maloprim
- Where
- The Gambia
- Volunteers
- 2,253 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Cause of Mortality, Cause of Neonatal Death
Defining Causes of Deaths in South and Southeast Asia
Brief Summary: Mortality data are important in low and middle-income countries to assess the population health status and trends.
- Conditions
- Cause of Mortality, Cause of Neonatal Death, Cause of Child Death, Cause of Maternal Death
- Trial name
- SEACTN-VA (NCT04595656)
- Testing
- verbal autopsy interview
- Where
- 5 sites in Bangladesh, Burma and 3 more
- Volunteers
- 3,413 people, healthy volunteers welcome
- Sponsor
- University of Oxford
Abuse Neglect Social, Deprivation, Maltreatment Syndrome (Infant or Child)
Nursing Led Interdisciplinary Intervention in Prevention of Girl Child Mortality and Maltreatment
In Northern India, skewed sex ratios, female feticide and higher child mortality rates for girls have become serious concern. The female child mortality as a result of son preference have increased during the last several…
- Trial name
- NCT02279368
- Testing
- Family Counselling and safeguarding
- Where
- 3 sites in India
- Volunteers
- 134 people, healthy volunteers welcome
- Sponsor
- Adwin Life Care