Clinical trials: Child Nutrition Sciences
Vitamin A Deficiency
The Efficacy of Pro-vitamin A Biofortified Cassava on Vitamin A Status in Nigerian Preschool Children
The study comprises an open-label randomized controlled trial investigating the efficacy of consuming a daily ration of pro-vitamin A biofortified cassava on vitamin A status of Nigerian children, aged 3-4 years old (n=200).
- Trial name
- CASSAVITA II (NCT02627222)
- Testing
- Pro-vitamin A biofortified cassava, White cassava
- Where
- Nigeria
- Volunteers
- 176 people, healthy volunteers welcome
- Sponsor
- Wageningen University
Obesity, Vitamin D Deficiency
Vitamin D and Vascular Health in Children
In this study, we will test the central hypothesis that enhancement of vitamin D status in obese and overweight children will improve their vascular health and their cardiovascular disease (CVD) and metabolic syndrome risk…
- Trial name
- NCT01797302
- Testing
- Vitamin D3
- Where
- United States
- Volunteers
- 225 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Obesity, Childhood, Diet Modification
A Trial to Improve the Healthiness of Packed Lunches in Primary School Aged Children
Public Health England's (PHE) Behavioural Insights Team are leading and fully funding a randomised controlled research trial in collaboration with Derby City Council's Public Health Team and the Health and Social Care Research…
- Trial name
- NCT03104777
- Testing
- Behaviourally Informed Intervention Materials
- Where
- United Kingdom
- Volunteers
- 17 people
- Sponsor
- Public Health England
Pediatric Nutrition
Impact of A Mobile Game on Pediatric Nutrition and Physical Activity
Overweight and obesity in children is on the rise globally and is rapidly growing in urban India. Studies have revealed that obesity is on the rise among children in India with many of them suffering from the problem even before…
- Trial name
- NCT04082195
- Testing
- Fooya mobile game, Uno board game
- Volunteers
- 104 people
- Sponsor
- Center for Communication and Change India
SEPSIS, MALNUTRITION, CHILD
Pancreatic Enzymes and Bile Acids in Acutely Ill Severely Malnourished Children
Children with severe malnutrition who are sick and admitted to hospitals have high mortality, usually because of infection. Malnourished children have more potentially harmful bacteria in their upper intestines than…
- Trial name
- PB-SAM (NCT04542473)
- Testing
- Pancreatic Enzyme, Ursodeoxycholic acid
- Where
- 4 sites in Bangladesh, Kenya and 2 more
- Volunteers
- 400 people
- Sponsor
- University of Oxford
Severe Malnutrition, Malnutrition
Characterizing the Gut Microbiota Alteration Associated With Severe Acute Malnutrition
The investigators performed two case-control studies in Niger and Senegal analysing fecal microbiota to characterize the specificity of the gut microbiota alteration associated with severe acute malnutrition (SAM).
- Conditions
- Severe Malnutrition, Malnutrition, Infant Nutrition Disorders, Child Nutrition Disorders
- Trial name
- NCT02413905
- Testing
- Stool samples
- Where
- 2 sites in Niger, Senegal
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Institut Hospitalo-Universitaire Méditerranée Infection
Child Nutrition, Fruit and Vegetable Intake
Pink and Dude Chef
The purpose of the study is to evaluate an afterschool program to teach nutrition through basic cooking skills. This after school extracurricular program increases the students' confidence, knowledge, and skills for cooking as…
- Conditions
- Child Nutrition, Fruit and Vegetable Intake, Healthy Food Choice, Healthy Food Preparation
- Trial name
- NCT01803997
- Testing
- Pink and Dude Chef Afterschool Cooking Program
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- USDA Grand Forks Human Nutrition Research Center
Obesity, Low Fitness
Fitness Training in Children
We hypothesize that improvement in cardiovascular fitness is associated with a greater improvement in insulin sensitivity than improvement in body composition (loss of body fat) is associated with insulin sensitivity.
- Trial name
- NCT00205296
- Testing
- exercise
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- University of Wisconsin, Madison
Prader-Willi Syndrome, Hyperphagia
Oxytocin vs. Placebo for the Treatment Hyperphagia in Children and Adolescents With Prader-Willi Syndrome
The investigators propose a randomized double-blind 8 week treatment trial of intranasal oxytocin (IN-OXT) vs. placebo in 24 subjects aged 5 to 18 years with PWS in order to assess IN-OXT's affect on (1) Eating behaviors (2)…
- Trial name
- OXT-PWS (NCT02629991)
- Testing
- Intranasal Oxytocin (IN-OXT)
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- Montefiore Medical Center
Childhood Obesity, Physical Activity
Development and Feasibility of an Intervention to Increase Physical Activity Among Young Children
The aim of this study is to develop, implement, and evaluate a novel intervention to increase physical activity and reduce sedentary behaviour among pre-school children, with the ultimate goal of reducing obesity among this age…
- Trial name
- NCT05754359
- Testing
- I'm an Active Hero (IAAH) Intervention Program
- Where
- Saudi Arabia
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Queen's University, Belfast
Acute Malnutrition in Childhood, Wasting
Simplified Treatment Protocol for Acute Malnutrition in Venezuela
Global acute malnutrition (GAM) in children under five is defined by being too thin for a given height and/or having the Mid-upper arm circumference less than a given threshold.
- Conditions
- Acute Malnutrition in Childhood, Wasting, Child Malnutrition
- Trial name
- NCT05543759
- Testing
- Ready-To-Use Therapeutic Food (RUTF)
- Where
- Venezuela
- Volunteers
- 307 people
- Sponsor
- UNICEF - Venezuela
Overweight, Obesity
Trim Tots Pre-school Obesity Prevention Programme
Randomised controlled trial of a lifestyle intervention programme for mothers and children aged 1-5 years aimed at prevention of overweight and obesity.
- Trial name
- TrimTots (NCT00675662)
- Testing
- Lifestyle intervention, waiting list control
- Where
- United Kingdom
- Volunteers
- 173 people, healthy volunteers welcome
- Sponsor
- Institute of Child Health
Childhood Obesity
Magnetic Resonance Imaging Assessment of Multiorgan Health in Obesity
The goal of this study is to quantify the body composition and organ fat distribution changes with obesity interventions in adolescents with severe obesity.
- Trial name
- FIT-YOUNG (NCT07702825)
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- Alder Hey Children's NHS Foundation Trust
Child Obesity
Systems of Underprivileged Preschoolers in Their Home and Preschool EnviRonment: Family Intervention Trial
This study will evaluate the effectiveness of SuperFIT, an integrative lifestyle intervention for preschool children. It will consist of both an preschool component and a family component and is aimed at increasing healthy…
- Trial name
- SuperFIT (NCT03021980)
- Testing
- SuperFIT
- Volunteers
- 212 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Child Nutritional Status, Household Dietary Diversity
Impact Evaluation of the DFID Programme to Accelerate Improved Nutrition of the Extreme Poor in Bangladesh
This is a randomized study in three areas of Bangladesh (Chars region where CLP operates, Haor region where Shiree operates, and urban slums where UPPR operates).
- Conditions
- Child Nutritional Status, Household Dietary Diversity, Maternal Nutrition Knowledge and Practices
- Trial name
- NCT02597608
- Testing
- CLP: Livelihoods, CLP: Nutrition, Shiree: Livelihoods
- Where
- Bangladesh
- Volunteers
- 11,340 people, healthy volunteers welcome
- Sponsor
- International Food Policy Research Institute
Pediatric Obesity, Weight-based Bullying
Trauma Therapy for Weight-Based Bullying in Children
The goal of this feasibility study is to learn whether a trauma therapy intervention for children and adolescents who have experienced weight-based bullying can be successfully delivered within a pediatric weight management…
- Conditions
- Pediatric Obesity, Weight-based Bullying, Psychological Trauma
- Trial name
- NCT07685990
- Testing
- Trauma Therapy for Weight-Based Bullying Informed by TF-CBT
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- Western University
Pediatric Obesity, Insulin Resistance
Effects of a Comprehensive Weight Management Program on Obese Adolescents and Children
To compare anthropometric and metabolic effects of a comprehensive weight management program on obese adolescents and children in comparison to regular clinical weight management visits.
- Conditions
- Pediatric Obesity, Insulin Resistance, Hyperinsulinemia
- Trial name
- NCT00409422
- Testing
- weight management program
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Yale University
Acute Malnutrition in Infancy (Disorder)
Optimizing Acute Malnutrition Management in Children Aged 6 to 59 Months in Niger (OptIMA Niger)
Acute malnutrition (AM) is a continuum condition, arbitrarily divided into severe and moderate categories (SAM, MAM) which are managed separately, with programs overseen by different agencies with different products and supply…
- Trial name
- NCT04698070
- Testing
- Nutritional Strategy - OptiMA, Nutritional Strategy - ComPAS, National nutritional Strategy (Niger)
- Where
- 4 sites in Niger
- Volunteers
- 2,304 people
- Sponsor
- Alliance for International Medical Action
Non-alcoholic Fatty Liver Disease, Obesity
The Influence of Autophagy on Fatty Liver
Non-alcoholic fatty liver disease (NAFLD) is one of the most common causes of chronic liver disease worldwide. It is not known why only some obese subjects develop NAFLD.
- Trial name
- NCT01988441
- Where
- Taiwan
- Volunteers
- 800 people
- Sponsor
- Far Eastern Memorial Hospital
Discriminate Obese Children at Risk for Diabetes.
Circulating microRNAs for Discriminating Obese Preschoolers at Risk of Diabetes
Childhood obesity certainly increases susceptibility to type 2 diabetes (T2D) in adulthood. Recently, microRNAs (miRNAs) are closely related to various diseases and have been suggested as valuable biomarkers.
- Trial name
- NCT02843139
- Where
- China
- Volunteers
- 535 people, healthy volunteers welcome
- Sponsor
- Nanjing Medical University
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