Clinical trials: Child Obesity, open to volunteers
Adolescent Overweight, Adolescent Obesity
Improving Sleep, Decision-Making, and Eating in Adolescents With Obesity
This study is being performed to understand the effects of a lifestyle modification and sleep intervention on weight loss outcomes in adolescence.
- Conditions
- Adolescent Overweight, Adolescent Obesity, Sleep, Eating Behaviors
- Trial name
- STAR (NCT06745570)
- Testing
- Lifestyle Modification and Sleep Intervention
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Nemours Children's Clinic
Diet Intervention, Physical Activity Intervention
Obesity Prevention in Children and Young People Treated for Acute Lymphoblastic Leukaemia with ALLTogether
Background Leukaemia is the most common cancer in children with 800 diagnoses per year in England. To survive, children need strong treatments like chemotherapy and steroids given usually through clinical trials.
- Conditions
- Diet Intervention, Physical Activity Intervention, Standard Care Control
- Trial name
- BREVARY (NCT06846294)
- Testing
- Diet, Diet and physical activity
- Where
- 2 sites in Spain, United Kingdom
- Volunteers
- 90 people
- Sponsor
- University of Exeter
Childhood Obesity Prevention
Digitally Delivered Child Obesity Prevention for Parents in Home Visiting Programs
The goal of this clinical trial is to determine feasibility and acceptability of a digitally-based obesity prevention intervention for mothers of infants participating in a home visitation program.
- Trial name
- NCT07230808
- Testing
- digital intervention + home visiting curriculum, Home visiting curriculum
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Florida
Autism Spectrum Disorder (ASD), Cardiometabolic Health Indicators
This Study Will Evaluate Cardiorespiratory and Muscular Fitness to Examine Associations With Anthropometric Characteristics and Other Indicators of Cardiometabolic Risk Among Patients With or Without Autism Spectrum Disorder
The goal of this observational study is to evaluate cardiorespiratory and muscular fitness in children with obesity, with and without autism spectrum disorder (ASD), and examine how fitness relates to body measurements, body…
- Conditions
- Autism Spectrum Disorder (ASD), Cardiometabolic Health Indicators, Cardiometabolic Risk Factors, Metabolic Syndrome
- Trial name
- ROACH (NCT07804680)
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- University of Virginia
Intrauterine Hyperglycemia, Pregnancy Outcomes
The Born in Guangzhou Cohort Study (BIGCS)
The Born in Guangzhou Cohort Study (BIGCS) was established to investigate the short- and long-term effects of exposure in early life on health consequences in Guangzhou, China.
- Conditions
- Intrauterine Hyperglycemia, Pregnancy Outcomes, Neurodevelopment, Immune Development
- Trial name
- BIGCS (NCT02526901)
- Testing
- No intervention
- Where
- China
- Volunteers
- 30,000 people, healthy volunteers welcome
- Sponsor
- Guangzhou Women and Children's Medical Center
Feasibility and Acceptability, Prevention Childhood Obesity
Starting Early to Prevent Obesity Using Telehealth (StEP OUT): Pilot RCT
The goal of this clinical trial is to test an online program that teaches healthy habits during pregnancy and infant to prevent early child obesity in Latino families.
- Trial name
- NCT07254065
- Testing
- StEP OUT, Infant Safety Education
- Where
- United States
- Volunteers
- 130 people
- Sponsor
- Northwell Health
Water, Child Nutrition
Water is K'é: Multi-level Intervention to Promote Healthy Beverage Choices Among Navajo Families
The goal of this clinical trial is to understand if a cultural intervention for Navajo families will improve healthy beverage habits, health outcomes, and family cohesion.
- Conditions
- Water, Child Nutrition, Family Dynamics, Healthy Nutrition
- Trial name
- NCT06020027
- Testing
- Water is K'é
- Where
- United States
- Volunteers
- 1,160 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Cardiometabolic Diseases, Obesity
Prenatal Programming of Childhood Obesity and Cardio Metabolic Disorders
This is a prospective 11-17 -years follow-up of two existing pregnancy cohort (PREDO) and prevention (RADIEL) studies. The main objective is to investigate the associations between maternal overweight, obesity, hypertensive…
- Trial name
- NCT05223530
- Where
- Finland
- Volunteers
- 750 people, healthy volunteers welcome
- Sponsor
- Helsinki University Central Hospital
Obesity, Childhood
MEditerranean LIfestyle in Pediatric Obesity Prevention
The current project is a randomized controlled multi-centre clinical trial, in a cohort of children aged 3 to 6 years at baseline and being at obesity risk.
- Trial name
- MELI-POP (NCT04597281)
- Testing
- Lifestyle intervention
- Where
- 3 sites in Spain
- Volunteers
- 738 people, healthy volunteers welcome
- Sponsor
- Luis A. Moreno Aznar
Crohn Disease, Ulcerative Colitis
Safety and Efficacy of Fecal Microbiota Transplantation
The gut microbiota is critical to health and functions with a level of complexity comparable to that of an organ system. Dysbiosis, or alterations of this gut microbiota ecology, have been implicated in a number of disease…
- Conditions
- Crohn Disease, Ulcerative Colitis, Celiac Disease, Irritable Bowel Syndrome
- Trial name
- NCT04014413
- Testing
- Fecal Microbiota Transplantation
- Where
- Hong Kong
- Volunteers
- 450 people
- Sponsor
- Chinese University of Hong Kong
Childhood Obesity, Obesity
EBT Fruit and Vegetable Prescription
Eating Better Together is a 6-month pilot program that teaches families about healthy eating and activity and provides home deliveries of fresh fruits and vegetables from a local retail partner.
- Trial name
- NCT05028205
- Testing
- Prevention Plus
- Where
- 2 sites in United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- The University of Tennessee, Knoxville
Prader-Willi Syndrome
A Study of Pitolisant in Patients With Prader-Willi Syndrome
This is a Phase 3, randomized, double-blind, placebo-controlled, multicenter, global clinical study to assess the efficacy and safety of pitolisant in patients living with Prader-Willi syndrome.
- Trial name
- NCT06366464
- Testing
- Pitolisant tablet
- Where
- 57 sites in United States, Australia and 11 more
- Volunteers
- 134 people
- Sponsor
- Harmony Biosciences Management, Inc.
Obesity, Adolescent
Preoperative Use of Liraglutide Additionally to Common Dietological Measures as Opposed to Dietological Measures Alone
The aim of the study is to investigate the effects of preoperative Saxenda (liraglutide). There are two groups, one group receives Saxena in addition to dietary measures when first seeking the operation, one group only diet.
- Trial name
- NCT06865365
- Testing
- Liraglutide daily (0.6-3.0mg, highest tolerable dose) additional to dietological measures and lifestyle optimization suggestions, Dietologic measures and lifestyle optimization for weight loss
- Volunteers
- 72 people
- Sponsor
- Medical University of Vienna
Pediatric Obesity
The Stress-obesity Axis: a Metabolomics Approach Towards Personalized Nutrition in Adolescents
The ultimate aim of this project is to establish a validated strategy that allows for personalized intervention in adolescents (11 to 17 years) whom are assigned a state of overweight or obesity.
- Trial name
- FAME (NCT06391671)
- Testing
- Collection of anthropometric data, biological samples (stool, saliva and hair), questionnaires (demographic data, psychological data, medical data)
- Where
- 7 sites in Belgium
- Volunteers
- 750 people, healthy volunteers welcome
- Sponsor
- University Ghent
Obesity, Childhood, Diet, Healthy
Whole Foods for Teens: A Pilot Dietary Intervention to Reduce Body Adiposity in Adolescents With Obesity
This study will address the following aims: Aim 1: Conduct an 8-week pilot RCT to examine the effects of a whole foods diet intervention on body adiposity in adolescents with obesity.
- Conditions
- Obesity, Childhood, Diet, Healthy, Body Weight Changes
- Trial name
- NCT06464497
- Testing
- Whole Foods MyPlate Group
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Vanderbilt University
Prader-Willi Syndrome
The Intervention of Obesity in Children With Prader-Willi Syndrome Using Prebiotics and Probiotics
Prader-Willi syndrome (PWS) is a rare genetic disease, with hyperappetite and severe obesity. At present, there is no effective drugs and interventions to help control the appetite of PWS patients.
- Trial name
- NCT05791604
- Testing
- probiotics including B. lactis B420, B. lactis HN019, B. animalis Bb-12, L. rhamnosus GG, Prebiotics with galactomannan and oligofructose
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Children's Hospital of Fudan University
Child Obesity, Cardiometabolic Health
Evaluating the Impact of a School-based Fruit and Vegetable Co-op on Cardiometabolic Child and Parents Health in a Persistent Poverty Area
The purpose of this study is to examine the effects of the (Brighter Bites (BB) intervention compared to a wait-list control group 9 months after the intervention on changes in primary child outcomes (HbA1c, and vegetable…
- Trial name
- NCT06570707
- Testing
- Brighter Bites
- Where
- United States
- Volunteers
- 720 people
- Sponsor
- The University of Texas Health Science Center, Houston
Obesity, Diabetes
Effects of Whole vs. Nonfat Milk Consumption on Body Composition in Children
This study will evaluate the effects of whole vs. nonfat milk consumption on body composition, cardiometabolic disease risk factors, and dietary quality.
- Conditions
- Obesity, Diabetes, Cardiovascular Diseases
- Trial name
- NCT05464186
- Testing
- Whole milk, Nonfat milk
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Boston Children's Hospital
Obesity, Adolescent, Healthy Nutrition
Wakaya: Rising Up for Choctaw Youth Health
Investigators will conduct a two-group randomized waitlist-control trial to assess the efficacy of the Wakaya: Rising Up for Choctaw Youth Health program on improving physical activity, reducing sedentary behaviors and improving…
- Conditions
- Obesity, Adolescent, Healthy Nutrition, Sedentary Behavior, Drug Abuse
- Trial name
- Wakaya (NCT05818384)
- Testing
- Wakaya: Rising Up for Choctaw Youth Curriculum
- Where
- 2 sites in United States
- Volunteers
- 176 people, healthy volunteers welcome
- Sponsor
- University of Washington
Childhood Obesity
Time Restricted Eating in Childhood Obesity (TRECO)
The goal of this clinical trial is to learn if time-restricted eating (TRE), an alternative method of reducing energy intake which has gained popularity in recent years, works to treat obesity in children.
- Trial name
- TRECO (NCT06583447)
- Testing
- Calorie-restricted diet (CRD), Time-restricted eating (TRE)
- Where
- 2 sites in China
- Volunteers
- 128 people
- Sponsor
- Xiaoyan Shi