Clinical trials: Child Weight
Human African Trypanosomiasis (HAT)
Efficacy and Safety of Fexinidazole in Children at Least 6 Years Old and Weighing Over 20 kg With Human African Trypanosomiasis (HAT) Due to T.b. Gambiense: a Prospective, Multicentre, Open Study, plug-in to the Pivotal Study
The aim of the study is to assess the efficacy and safety of an oral regimen of fexinidazole (once daily for 10 days) in the treatment of stage 1 and stage 2 T.b.
- Trial name
- NCT02184689
- Testing
- fexinidazole
- Where
- Democratic Republic of the Congo
- Volunteers
- 125 people
- Sponsor
- Drugs for Neglected Diseases
Childhood Obesity
Biofeedback Gait Retraining to Reduce Lower Extremity Impact in Obese Children
The purpose of the study is to explore if self biofeedback program can reduce ground reaction force (GRF) from the lower extremity of the body and in the knee in particular and help obese children to avoid knee injuries.
- Trial name
- NCT02580825
- Testing
- Biofeedback gait retraining, Exercise
- Where
- Israel
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Meir Medical Center
Obesity
Development of a Group Prenatal Care Intervention to Address Maternal and Child Non-Communicable Disease (NCD) Risk in American Samoa
To test the efficacy of a group prenatal care intervention to reduce the risk of obesity related health conditions during and after pregnancy in obese mothers and their infants.
- Trial name
- NCT04025268
- Testing
- Group Prenatal Care (GPNC), Standard of Care
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Yale University
Pediatric Obesity, Pediatric Asthma
Inspiratory Pulmonary Rehabilitation for Children With Obesity and Asthma
This is a single-center, randomized, SHAM-controlled, parallel assignment, double-masked,8-week interventional study among children aged 8-17 years (not yet 18 years old) of age with obesity and asthma.
- Trial name
- iPro (NCT05608668)
- Testing
- Pro2 - 60% of participant's MIP, Pro2 - 15% of participant's MIP
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Duke University
Overweight and Obesity, Non-alcoholic Fatty Liver Disease
Nonalcoholic Fatty Liver Disease and Atherosclerotic Risk in Children
Nonalcoholic fatty liver disease is a serious health condition in overweight children which can lead to heart disease. This project will examine the links between liver health and cardiovascular risk factors in overweight and…
- Trial name
- SMART (NCT02383485)
- Testing
- Exercise, After-school program
- Where
- United States
- Volunteers
- 175 people, healthy volunteers welcome
- Sponsor
- Augusta University
High Intensity Interval Training, Child Obesity
The Effect of HIIT in Handling Obesity in Children
In this study the investigators wish to investigate whether a short duration High-intensity Interval Training(HIT) is superior to a moderate activity training modus with regards to improving weight-loss, Blood pressure and sleep…
- Trial name
- NCT03433690
- Testing
- HIIT, Moderate training
- Volunteers
- 30 people
- Sponsor
- Regionshospital Nordjylland
Growth, Overweight
Diet and Well-being of Young Danish Children Born by Obese Mothers
The overall aim is to provide a detailed description of growth, development and risk factors for later disease, especially obesity and metabolic disease in infants born by obese mothers and to compare them with a group of infants…
- Conditions
- Growth, Overweight, Metabolic Syndrome, Obesity
- Trial name
- SKOT II (NCT02377973)
- Where
- Denmark
- Volunteers
- 184 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Overweight, Obesity
Trim Tots Pre-school Obesity Prevention Programme
Randomised controlled trial of a lifestyle intervention programme for mothers and children aged 1-5 years aimed at prevention of overweight and obesity.
- Trial name
- TrimTots (NCT00675662)
- Testing
- Lifestyle intervention, waiting list control
- Where
- United Kingdom
- Volunteers
- 173 people, healthy volunteers welcome
- Sponsor
- Institute of Child Health
Acute Malnutrition in Childhood, Wasting
Simplified Treatment Protocol for Acute Malnutrition in Venezuela
Global acute malnutrition (GAM) in children under five is defined by being too thin for a given height and/or having the Mid-upper arm circumference less than a given threshold.
- Conditions
- Acute Malnutrition in Childhood, Wasting, Child Malnutrition
- Trial name
- NCT05543759
- Testing
- Ready-To-Use Therapeutic Food (RUTF)
- Where
- Venezuela
- Volunteers
- 307 people
- Sponsor
- UNICEF - Venezuela
Down Syndrome, Child Obesity
HomeGrown: A Family-based Lifestyle Intervention to Support Healthy Development of Young Children With Down Syndrome
The goal of this project is to evaluate an adapted health promotion program, HomeGrown, designed to improve the health of young children with Down syndrome by supporting families in making healthy home environmental changes.
- Trial name
- HomeGrown (NCT07296861)
- Testing
- The HomeGrown, Waitlist
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- UNC Lineberger Comprehensive Cancer Center
Asthma, Overweight
Weight-reduction Intervention in Asthmatic Children With Overweight/Obesity
The purpose of this study is to determine the efficacy of a multifactorial intervention with weight reduction, behavioural therapy, and physical exercise on the severity and control of asthma in obese children.
- Conditions
- Asthma, Overweight, Obesity
- Trial name
- NCT00998413
- Testing
- Multifaceted intervention
- Where
- 2 sites in Netherlands
- Volunteers
- 87 people
- Sponsor
- Maastricht University Medical Center
Schizophrenia, Schizoaffective Disorder
Second-Generation Antipsychotic Treatment Indication Effectiveness And Tolerability In Youth (Satiety) Study
The purpose of this study is to get a better understanding of the side effect burden and identify predictors of psychotic, mood and aggressive disorders in children and adolescents.
- Conditions
- Schizophrenia, Schizoaffective Disorder, Schizophreniform Disorder, Psychotic Disorder, Not Otherwise Specified
- Trial name
- SATIETY (NCT01269710)
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- University of North Carolina, Chapel Hill
Diabetes
Food Intake and Appetite in the Children of Mothers With Diabetes
This protocol is for study of the effect of inhibition of parasympathetic outflow on insulin secretion and glucose metabolism. Insulin secretion will be measured during infusions of escalating doses of atropine.
- Trial name
- NCT00339313
- Where
- United States
- Volunteers
- 240 people
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Epilepsy, Obese
Pharmacokinetics of Anti-epileptic Drugs in Obese Children
The study is a prospective, multi-center, open-label clinical trial. Study's purpose is to characterize the pharmacokinetics and safety of four oral anti-epileptics drugs (levetiracetam, valproic acid [divalproex sodium ER or…
- Trial name
- NCT02993861
- Testing
- Anti-epileptics
- Where
- 10 sites in United States
- Volunteers
- 106 people
- Sponsor
- Christoph P Hornik, MD MPH
Cerebral Palsy, Spastic Diplegia
Gait Rehabilitation in Diplegic Children
Background: Standing and walking serve an individual's basic need to move from place to place, and both are the most common activities that people do on a daily basis.
- Trial name
- NCT05294874
- Testing
- gait training
- Where
- Egypt
- Volunteers
- 45 people
- Sponsor
- Cairo University
Asthma in Children, Obesity
Managing AsThma AnD Obesity Related Symptoms (MATADORS) Feasibility Study
The purpose of this 4 week pilot study is to test the use of a mobile application (also commonly referred to as an app) designed to help increase self-management strategies among youth that have asthma and obesity.
- Conditions
- Asthma in Children, Obesity, Obesity, Adolescent, Obesity, Childhood
- Trial name
- MATADORS (NCT05742646)
- Testing
- MATADORS, MATADORS Control
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Childhood Obesity
Respiratory Effects of Obesity in Children: Longitudinal Consequences After 6 Years of Aging
The purpose of the study is to re-examine body composition, respiratory function, exercise tolerance, and dyspnea on exertion (DOE) in children with obesity (CWO) and children without obesity (CWOO) who were originally studied as…
- Trial name
- NCT06447246
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Child Obesity
Enhancing Family Based Treatment of Childhood Obesity Through Social Networks
The purpose of this study is to develop a Social Network Engagement (SNE) Intervention that will be integrated into a standard treatment program for childhood overweight.
- Trial name
- CONNECT (NCT02206529)
- Testing
- Social Network Engagement+Std Treatment, Standard Treatment
- Volunteers
- 25 people
- Sponsor
- Kaiser Permanente
Obesity, Overweight
Mobile Attention Retraining in Overweight Female Adolescents
Background: People are constantly exposed to unhealthy foods. Some studies of adults show that training attention away from unhealthy foods might reduce overeating.
- Conditions
- Obesity, Overweight, Binge Eating, Healthy Volunteers
- Trial name
- NCT02977403
- Testing
- Attention Bias Retraining
- Where
- United States
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Schizophrenia, Schizoaffective Disorder
Efficacy and Tolerability Study of Betahistine to Ameliorate Antipsychotic Associated Weight Gain
The study attempts to evaluate a histamine analog long used for the treatment of Meniere's disease, betahistine, that shows promise in reversing the antihistaminergic effects thought to be involved in antipsychotic induced weight…
- Conditions
- Schizophrenia, Schizoaffective Disorder, Schizophreniform Disorder, Bipolar I Disorder
- Trial name
- NCT00709202
- Testing
- Betahistine
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Nathan Kline Institute for Psychiatric Research
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