Clinical trials: Childhood Anxiety
Anxiety Disorder, Anxiety Disorder of Childhood
Web-based Attention Bias Modification Treatment for Childhood Anxiety Disorders
Anxiety disorders are the most common childhood psychiatric disorders, with prevalence rates as high as 15% to 20%. Success rates of the first choice treatment strategy (i.e. Cognitive Behavioural Therapy; CBT) are around 50%.
- Conditions
- Anxiety Disorder, Anxiety Disorder of Childhood, Separation Anxiety Disorder of Childhood, Early Onset, Specific Phobia
- Trial name
- ATTENTIO (NCT03764644)
- Testing
- Combined ABMT and CBT
- Where
- Netherlands
- Volunteers
- 55 people
- Sponsor
- Erasmus Medical Center
Treatment-Related Cancer
Acupressure for Children in Treatment for a Childhood Cancer
Background: Despite advances in symptom management, children undergoing cancer treatment or receiving a chemotherapy-based Hematopoietic Stem Cell Transplant (HSCT) often suffer from moderate to severe symptoms of…
- Trial name
- ACT-CC (NCT03313193)
- Testing
- Acupressure for Children in Treatment for a Childhood Cancer
- Where
- United States
- Volunteers
- 95 people
- Sponsor
- University of California, San Francisco
Primary Headache, Psychological Distress
Impact of MBI on Biopsychosocial Factors and QOL in Children With Primary Headaches
The Randomized Controlled Trial aims to evaluate the effectiveness of a Mindfulness-Based Intervention (MBI) in improving the quality of life and reducing psychological distress in children with primary headaches.
- Conditions
- Primary Headache, Psychological Distress, Emotion Regulation, Childhood Trauma
- Trial name
- NCT06822673
- Testing
- Mindfulness Based Intervention
- Where
- Pakistan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Fatima Jinnah Women University
Obsessive-Compulsive Disorder, Autism Spectrum Disorder
Riluzole to Treat Child and Adolescent Obsessive-Compulsive Disorder With or Without Autism Spectrum Disorders
This study will examine the effectiveness of riluzole for treating Obsessive-Compulsive Disorder in Youth, Including those with Autism Spectrum Disorders.
- Conditions
- Obsessive-Compulsive Disorder, Autism Spectrum Disorder, Autism, Asperger Disorder
- Trial name
- NCT00251303
- Testing
- Riluzole
- Where
- United States
- Volunteers
- 78 people
- Sponsor
- National Institute of Mental Health (NIMH)
Anxiety Disorders
Effectiveness of a Family-Based Treatment for Preventing Anxiety Disorders in At-Risk Children
This study will test the effectiveness of a family-based, cognitive behavioral therapy (CBT)-based program for preventing anxiety disorders in at-risk children.
- Trial name
- NCT00847561
- Testing
- Family-based CBT, Information Monitoring
- Where
- United States
- Volunteers
- 136 people
- Sponsor
- Johns Hopkins University
Long-term Health Conditions
An Acceptance and Commitment Therapy Psychoeducation Single Session Intervention on Childhood Anxiety for Carers of Children With a Long-Term Health Condition
The goal of this feasibility study was to assess the acceptability and feasibility of the ACT-based training package for carers of children with a long-term health condition (LTHC) who also experience anxiety.
- Trial name
- NCT07656220
- Testing
- Psychoeducation for anxiety
- Where
- United Kingdom
- Volunteers
- 17 people
- Sponsor
- University of East Anglia
Social Anxiety Disorder, Social Anxiety
Assessing Mechanisms of Anxiety Reduction in Animal-assisted Interventions
Adolescence and young adulthood is a critical period for the development of social anxiety, which is often linked to other mental health challenges such as depression, mood disorders, and substance abuse.
- Conditions
- Social Anxiety Disorder, Social Anxiety, Social Anxiety Disorder of Childhood
- Trial name
- NCT03249116
- Testing
- animal-assisted intervention, active control
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Tufts University
Childhood Cancer, Depressive Symptoms
Cultivating Resilience in Oncology Practice
The purpose of the CROP study is to investigate the potential to cultivate psychological resources and resilience in childhood cancer patients and their family members using a mobile phone-based intervention.
- Conditions
- Childhood Cancer, Depressive Symptoms, Anxiety Disorders and Symptoms, Mental Health Issue
- Trial name
- CROP (NCT04902313)
- Testing
- Awareness and insight Modules (AiM)
- Where
- Sweden
- Volunteers
- 40 people
- Sponsor
- Linkoeping University
Anxiety Disorder of Childhood, Fear
Addressing Anxiety in 2-3-Year-Olds: A Pilot Intervention Study
The purpose of this study is to test the feasibility and efficacy of intervening with 2-year-old children with elevated temperamental Fear and/or Shyness or 3-year-old children with elevated anxiety and their parents, using a…
- Conditions
- Anxiety Disorder of Childhood, Fear, Shyness
- Trial name
- NCT04039243
- Testing
- Being Brave, Parent Education
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Anxiety, Abdominal Pain
The Probiotic Study: Using Bacteria to Calm Your Mind
The investigators seek to conduct the first open-label trial of probiotics in young children to reduce their anxiety and abdominal pain.
- Trial name
- NCT02711800
- Testing
- Lactobacillus rhamnosus
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- Nancy Zucker
Inflammatory Bowel Disease
Integrated Behavioral Health Innovations in Childhood Chronic Illness Care Delivery Systems
Study design: At baseline, all adolescents and young adults with IBD ages 12-21 years will be screened for anxiety and depression symptoms using the PHQ-9 and the Screen for Child Anxiety Related Disorders (SCARED) during a…
- Trial name
- NCT02740309
- Testing
- Integrated Brief Behavior Therapy (IBBT) Intervention, Treatment as usual
- Where
- United States
- Sponsor
- NYU Langone Health
Pediatric Oncology
The Effects of Nonpharmacological Methods Used in Subcutaneous Application on Pain, Anxiety, and Fear Levels in Children
Childhood cancers are increasing globally and require long-term invasive treatments, particularly subcutaneous applications that often cause pain, swelling, and anxiety.
- Trial name
- NCT07163104
- Testing
- Kaleidoscope, Buzzy, Cognitive behavioral intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people
- Sponsor
- Zubeyde Ezgi Ercelik
Obsessive Compulsive Disorder
Attention Training for Childhood Obsessive Compulsive Disorder
Voluntary and involuntary attention processes are thought to play an important role in the development and maintenance of anxiety disorders including OCD.
- Trial name
- AMP-OCD (NCT02114918)
- Testing
- Attention Modification Program, Attention Control Condition
- Where
- United States
- Volunteers
- 47 people
- Sponsor
- University of California, Los Angeles
Acute Lymphoblastic Leukemia, Childhood Acute Leukemia
The Effect of Mandala on Anxiety and Fear Levels in Children With Leukemia Before Intrathecal Chemotherapy Treatment
This study aims to examine the effect of mandala coloring activity, administered before intrathecal chemotherapy treatment in children with leukemia, on pre-procedure anxiety and fear in children.
- Conditions
- Acute Lymphoblastic Leukemia, Childhood Acute Leukemia, Acute Myeloblastic Leukaemia
- Trial name
- NCT07203742
- Testing
- mandala painting
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Ege University
Vaccine Hesitancy, Health Education
Effect of Primary Care Education on Parents' Health-Related Perceptions and Attitudes
This study aims to evaluate the effect of a structured education program delivered in primary health care settings on parents of children aged 0-2 years.
- Conditions
- Vaccine Hesitancy, Health Education, Digital Health Literacy, Eco-anxiety
- Trial name
- NCT07381088
- Testing
- Structured Education Program
- Where
- Turkey (Türkiye)
- Volunteers
- 173 people, healthy volunteers welcome
- Sponsor
- Yuzuncu Yil University
Obsessive-Compulsive Disorder
Family Based Treatment of Early Childhood Obsessive Compulsive Disorder
This study will evaluate a treatment program for young children with Obsessive Compulsive Disorder (OCD) and their families.
- Trial name
- NCT00055068
- Testing
- Cognitive Behavioral Therapy (CBT), Relaxation Training
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- Rhode Island Hospital
Stress-related Problem, Stress, Emotional
Effects of Parent-Adolescent Joint I-Interventions for Adolescents with Adverse Childhood Experiences
The study aims to examine the effectiveness of internet-based Parent-Adolescent Joint Interventions in improving the mental health outcomes of participants, specifically by reducing symptoms of depression, anxiety, and PTSD, as…
- Trial name
- EASY-PEP-i (NCT06650696)
- Testing
- PCE promotion, Psychoeducation, Emotiaonl skill enhancement
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Peking University
Childhood Cancer, Childhood Cancers
Examination of the Relationship Between Quality of Life and Caregiving Burden Among Caregivers of Pediatric Oncology Patients
Primary Aim The primary aim of this study is to determine the quality of life and caregiving burden levels of caregivers of pediatric oncology patients and to examine the relationship between these two variables.
- Conditions
- Childhood Cancer, Childhood Cancers, Caregiver Subjective Burden, Primary Caregivers of Children Newly Diagnosed With Cancer
- Trial name
- NCT07308301
- Testing
- Assessment of caregiver quality of life and burden
- Volunteers
- 95 people, healthy volunteers welcome
- Sponsor
- Fatma Beyza Akdeniz
Sleep Problems, Maternal Anxiety
Sleep Patterns in Children Aged 0-36 Months and Maternal Anxiety and Depression
In this study, the investigators aimed to investigate the relationship between the sleep patterns of children aged 0-36 months hospitalized in the general pediatrics clinic and their mothers' anxiety and depression levels.
- Trial name
- NCT07476612
- Where
- Turkey (Türkiye)
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Başakşehir Çam & Sakura City Hospital
Anxiety Disorder of Childhood
Brief, Remote Treatment of Youth Injection Phobia and Measurement of Novel, Disorder-congruent Cognitive Bias Tasks
This study is investigating the acceptability, feasibility, and preliminary efficacy of a brief, remote treatment for youth injection phobia.
- Trial name
- NCT04972006
- Testing
- Remote, intensive intervention for injection phobia
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Boston University Charles River Campus