Clinical trials: Childhood Asthma
Asthma in Children
Mold Exposure and Impact on Asthma Control in French Asthmatic Children
Observational, multicenter, study conducted in 12 hospitals in the Nord and Pas-De-Calais departments. The aim of this study is to describe the relationship between reported exposure to molds and asthma control in a pediatric…
- Trial name
- CHAMPIASTHMA (NCT04918394)
- Testing
- Questionnaire of Mold / moisture exposure
- Where
- 10 sites in France
- Volunteers
- 451 people
- Sponsor
- University Hospital, Lille
Asthma in Children
Prognosis and Influencing Factors of Asthma in Children Aged 5-12 Years
The goal of this observational study is to 1)analyze the basic information of confirmed cases of asthma in children aged 5-12 years old hospitalized in the First Affiliated Hospital of Guangzhou Medical University from 2009 to…
- Trial name
- NCT05765383
- Where
- China
- Volunteers
- 400 people
- Sponsor
- Guangzhou Institute of Respiratory Disease
Asthma in Children, Asthma Chronic
Asthma Ctrl SMART Trial
The primary objective is to examine the efficacy of an mHealth adherence intervention (Asthma Ctrl) on adherence to daily inhaled corticosteroids as measured by electronically monitored adherence in adolescents with asthma.
- Trial name
- NCT07512622
- Testing
- Asthma Ctrl, Asthma Ctrl+, Control
- Where
- 2 sites in United States
- Volunteers
- 389 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Asthma in Children
SMART Implementation-Effectiveness Trial 2
While single maintenance and reliever therapy (SMART) has been the preferred management strategy for Step 3 and 4 (moderate/severe) asthma management since the 2020 NIH asthma guideline updates, adoption of SMART has not been…
- Trial name
- SMART SIMPLE (NCT07138027)
- Testing
- Clinical decision support + education (CDS+) and population health management (PHM), Control
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Children's Hospital of Philadelphia
Respiration Disorders, Respiratory Disease
The Gut-Lung Axis and Respiratory Illness in Children
The goal of this single-centre observational study conducted at the Royal Hospital for Children in Glasgow, Scotland, is to employ a multi-omics approach to investigate the "gut-lung axis" in health and disease.
- Conditions
- Respiration Disorders, Respiratory Disease, Asthma in Children, Wheezing
- Trial name
- NCT06271213
- Testing
- observational only - no interventions as part of study
- Where
- United Kingdom
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- NHS Greater Glasgow and Clyde
Asthma in Children
Personalised Outcomes in Children With Recurrent Wheeze
This project aims to develop a PROM for preschool children with recurrent wheeze. Nearly one third of children will have at least one episode of wheeze in the first five years of life.
- Trial name
- NCT03858010
- Testing
- Wheeze and me questionnaire
- Where
- United Kingdom
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Imperial College Healthcare NHS Trust
Asthma
Using the Telephone to Improve Care in Childhood Asthma
Asthma is the most common chronic disease of childhood and a major cause of morbidity in the United States. If asthma symptoms are controlled, a child with asthma can stay well and lead a normal life.
- Trial name
- NCT00660322
- Testing
- Telephone Asthma Program
- Where
- United States
- Volunteers
- 362 people
- Sponsor
- Agency for Healthcare Research and Quality (AHRQ)
Asthma
Exercise Training in Asthma Children
The purpose of this study is to assess the effects of a physical training program with active video game in inflammatory markers, quality of life variables , clinical control and physical and functional respiratory assessment of…
- Trial name
- NCT01438294
- Testing
- Video game group, Aerobic exercise group
- Where
- Brazil
- Volunteers
- 36 people
- Sponsor
- Hospital Sirio-Libanes
Asthma
A Computer-Based ED Intervention to Improve Pediatric Asthma Medicine Adherence
Asthma is common in children and impacts their health. There are effective medications for improving asthma, but some families have difficulty using medicines on a regular basis.
- Trial name
- ED-AMAP (NCT02787174)
- Testing
- Asthma Medication Adherence Education
- Where
- United States
- Volunteers
- 109 people
- Sponsor
- Rhode Island Hospital
Asthma
Evaluation of a Shared Decision Making Portal for Pediatric Asthma
This pilot intervention study will test the feasibility and acceptability and explore the outcomes of a primary care-based shared decision making (SDM) electronic medical record (EMR)-based portal that provides education, elicits…
- Trial name
- NCT01715389
- Testing
- MyAsthma Patient Portal
- Where
- United States
- Volunteers
- 81 people
- Sponsor
- Children's Hospital of Philadelphia
Asthma
Efficacy of Ciclesonide Inhaled Once Daily Versus Fluticasone Propionate Inhaled Twice Daily in Children With Asthma (6 to 11 y) (BY9010/M1-206)
The aim of the study is to compare the efficacy of ciclesonide versus fluticasone propionate on lung function, symptoms, and use of rescue medication in children with persistent asthma.
- Trial name
- NCT00163462
- Testing
- Ciclesonide
- Where
- 57 sites in Brazil, Germany and 4 more
- Volunteers
- 750 people
- Sponsor
- AstraZeneca
Asthma in Children
N-WATCH: Nottingham Wheeze Assessment in Tidal Children
Children with long-term lung diseases like asthma need better techniques for diagnosis and monitoring of their disease. With better monitoring, it is anticipated that children and their carers will be able to manage their disease…
- Trial name
- N-WATCH (NCT07833826)
- Testing
- N-Tidal
- Where
- 2 sites in United Kingdom
- Volunteers
- 340 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Asthma
To Evaluate the Efficacy of Supplementation With L. Reuteri + Vit. D3 in Asthmatic Children
The purpose of this project is to evaluate in a randomized clinical trial, double-blind, controlled, the effects of a dietary supplement containing Lactobacillus reuteri DSM 17938 and vitamin D3 in reducing bronchial inflammation…
- Trial name
- NCT02734446
- Testing
- Reuterin D3 drops
- Where
- Italy
- Volunteers
- 52 people
- Sponsor
- University of Campania Luigi Vanvitelli
Asthma in Children
Digital Respiratory Game in Asthma
This study aims to examine the effects of a digital game designed for respiratory training in childhood asthma. Fifteen children aged 8-14 years with asthma were included in the study.
- Trial name
- NCT05930847
- Testing
- Digital Game Application, Use of medication for asthma
- Where
- Turkey (Türkiye)
- Volunteers
- 15 people
- Sponsor
- Ege University
Asthma (Diagnosis)
Pediatric Asthma Trial of Corticosteroid Heterogeneity (PATCH): Trial of Dexamethasone Versus Methylprednisolone for Pediatric Critical Asthma
Acute asthma exacerbation is caused by dysregulated pulmonary inflammatory pathways such that standard treatment includes prompt administration of exogenous systemic corticosteroids (SCs), but there remains an ongoing dialogue…
- Trial name
- PATCH (NCT07455396)
- Testing
- Dexamethasone (0.6mg/kg; Max 16mg) Once Daily, Dexamethasone (0.25 mg/kg/dose, Max dose 16mg) every 6-hours, Methylprednisolone
- Where
- United States
- Volunteers
- 159 people
- Sponsor
- Johns Hopkins All Children's Hospital
Asthma
Pilot Study of Magnesium Infusions in Pediatric Asthma
This is a prospective randomized pilot study that seeks to address the research question: In children with moderate-to-severe asthma, do intravenous magnesium infusions added to standard Pediatric intensive care unit (PICU)-level…
- Trial name
- NCT01522040
- Testing
- Magnesium Sulfate
- Where
- United States
- Sponsor
- University of Louisville
Asthma in Children, Bronchitis
Clinical Validation of Omron WheezeScan
The WheezeScan sensitivity and specificity are set to statistically prove equal to or higher values than the predicate PulmoTrack device model 2020.
- Conditions
- Asthma in Children, Bronchitis, Bronchiolitis
- Trial name
- NCT04144699
- Where
- 15 sites in United States
- Volunteers
- 240 people
- Sponsor
- Omron Healthcare Co., Ltd.
Asthma
Childhood Asthma Management in Primary Care: Implementation Of Exhaled Nitric Oxide and Spirometry Testing
What are the capacity and training needs in general practice to implement routine spirometry and eNO testing in children aged 5-16 years? Asthma is the commonest long-term disease of childhood in the United Kingdom (UK).
- Trial name
- CHAMPIONS (NCT02913872)
- Where
- 2 sites in United Kingdom
- Volunteers
- 613 people
- Sponsor
- University of Leicester
Asthma in Children, Vaccine Adverse Reaction
Safety of LAIV4 in Children With Asthma
This is a prospective randomized, open label clinical trial in approximately 300 children aged 5-11 years with a physician diagnosis of persistent asthma.
- Conditions
- Asthma in Children, Vaccine Adverse Reaction, Vaccine Reaction, Asthma
- Trial name
- NCT03600428
- Testing
- Live Attenuated Influenza Vaccine (LAIV), Inactivated Influenza Vaccine (IIV)
- Where
- 3 sites in United States
- Volunteers
- 152 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Hernia, Diaphragmatic
Early Childhood Follow-up of Congenital Diaphragmatic Hernia Survivors
The primary objective of this study is to determine the medical and neurodevelopmental outcomes of congenital diaphragmatic hernia (CDH) survivors at school-age (4-6 years) follow-up.
- Trial name
- CDH (NCT01029665)
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Duke University