Clinical trials: Childhood Cancer Survivors
Long-term Effects Secondary to Cancer Therapy in Adults, Pediatric Cancer
Exercise Intervention in Adolescent and Young Adult Cancer Survivors
Adolescent and young adult (AYA) survivors of cancer face a future of persistent medical issues across a wide spectrum of diseases One study examining health data from this cohort (ages 15-29) reported significantly higher rates…
- Trial name
- NCT04265638
- Testing
- Exercise
- Where
- 3 sites in United States
- Volunteers
- 66 people
- Sponsor
- Indiana University
Leukemia, Lymphoma
Quality of Life in Children Treated for Cancer
RATIONALE: Questionnaires that measure quality of life may improve the ability to plan treatment for children with cancer. PURPOSE: This randomized clinical trial is studying the quality of life in children treated for cancer.
- Conditions
- Leukemia, Lymphoma, Unspecified Childhood Solid Tumor, Protocol Specific
- Trial name
- NCT00005881
- Testing
- Quality of Life Forms
- Where
- 17 sites in United States
- Volunteers
- 538 people
- Sponsor
- Children's Oncology Group
Malignant Childhood Neoplasm
Effectiveness of an Integrated Programme in Promoting the Regular Physical Activity Among Childhood Cancer Survivors
Background.There is some evidence that engaging in regular moderate-intensity physical activity may help ameliorate cancer-related fatigue experienced by childhood cancer survivors, which eventually improve their quality of life.
- Trial name
- NCT01803672
- Testing
- health talk and adventure-based training
- Where
- China
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Cancer Survivor, Pediatric Cancer
Vascular Endothelial Inflammation and Dysfunction in Pediatric Long-term Cancer Survivors
Survivors of childhood cancer have an increased risk of death from cardiovascular disease due to both the therapies they received while undergoing treatment and diet and lifestyle factors.
- Trial name
- NCT02032121
- Testing
- Blood specimen, Echocardiography
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- University of Miami
Cancer, Pediatric Cancer
Digital Art Therapy for Young Cancer Survivors
This is a single-site, single-arm, interventional study assessing the feasibility of the ARTCan Therapy Application (App) and whether it is an acceptable means of administering art therapy to young adult cancer survivors.
- Conditions
- Cancer, Pediatric Cancer, Pediatric Malignancies, Pediatric Sarcoma of Soft Tissue
- Trial name
- NCT06789666
- Testing
- ARTCan App
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- UNC Lineberger Comprehensive Cancer Center
Intracranial Germ Cell Tumor, Intracranial Germ Cell CNS Tumor, Childhood
Surveillance of Association of Immune Status and Prognosis of CNS Germ Cell Tumor Survivors
Platinum-based chemotherapy, alternating at 21-days intervals with cycles of ifosfamide, cisplatin, and etoposide (ICE) and subsequently received radiotherapy were considered as standard treatment for intracranial germ cell…
- Conditions
- Intracranial Germ Cell Tumor, Intracranial Germ Cell CNS Tumor, Childhood, Surgery
- Trial name
- NCT04909307
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Chengcheng Guo
Hematopoietic and Lymphoid Cell Neoplasm, Malignant Solid Neoplasm
Carvedilol in Preventing Heart Failure in Childhood Cancer Survivors
This phase IIb trial studies how well low-dose carvedilol works in preventing heart failure in cancer survivors exposed to high dose anthracyclines for management of childhood cancer.
- Trial name
- NCT02717507
- Testing
- Carvedilol, Laboratory Biomarker Analysis, Pharmacogenomic Study
- Where
- 91 sites in United States, Australia and 2 more
- Volunteers
- 196 people
- Sponsor
- Children's Oncology Group
Brain Neoplasms, Child
Effectiveness of Musical Training in Hong Kong Chinese Childhood Brain Tumor Survivors
This study aims to work out the effectiveness (effect size) of the musical training intervention in reducing depressive symptoms, improving self-esteem and quality of life among childhood brain tumour survivors and to examine the…
- Trial name
- NCT03399864
- Testing
- musical training, usual care
- Where
- China
- Volunteers
- 60 people
- Sponsor
- The University of Hong Kong
Brain Tumor, Pediatric, Cancer-related Fatigue
Methylphenidate in Pediatric Brain Tumor Survivors With Cancer-related Fatigue
Cancer-related fatigue is a common and debilitating late effect in pediatric brain tumor survivors. Currently, evidence-based recommendations to ameliorate this condition are lacking.
- Conditions
- Brain Tumor, Pediatric, Cancer-related Fatigue, Methylphenidate
- Trial name
- EMBRAIN (NCT06905587)
- Testing
- Methylphenidate (MPH)
- Where
- 4 sites in Denmark
- Volunteers
- 50 people
- Sponsor
- Odense University Hospital
Cancer, Parent
Adapting The Fear Of Recurrence Therapy (FORT) for Parents and Establishing Acceptability and Feasibility
Clinical levels of fear of cancer recurrence (FCR) affect up to 59% of adult cancer survivors. Family caregivers experience equal or greater levels of FCR, which has been linked to lower quality of life and increased distress.
- Conditions
- Cancer, Parent, Fear of Cancer Recurrence, CBT
- Trial name
- Parent-FORT (NCT06872840)
- Testing
- Parent Fear of Recurrence Therapy (Parent-FORT)
- Where
- Canada
- Volunteers
- 36 people
- Sponsor
- University of Ottawa
Congenital Heart Disease (CHD), Hematologic Malignancy
Impact of Congenital Heart Disease on the Prognosis of Childhood Hematological Neoplasms: A Multicenter Cohort Study
This study aims to determine whether congenital heart disease increases chronic health risks and mortality in childhood hematological tumor survivors, explore potential shared genetic factors between these conditions, identify…
- Trial name
- NCT07249138
- Where
- 18 sites in China
- Volunteers
- 800 people
- Sponsor
- Children's Hospital of Fudan University
Childhood Cancer, Mobility Limitation
Telehealth Based Intervention to Improve Functional Capacity in Survivors of Childhood Cancer With Significantly Limited Exercise Tolerance
The participants are asked to take part in this clinical trial, a type of research study. The participants are SJLIFE study participants and may have a hard time exercising (exercise intolerance) due to side effects of cancer…
- Trial name
- NCT04714840
- Testing
- Exercise testing results, Individually tailored exercise program (INT), Generalized exercise recommendations (AC)
- Where
- United States
- Volunteers
- 181 people
- Sponsor
- St. Jude Children's Research Hospital
Childhood Cancer, Survivorship
Sexual Function Screening in Childhood Cancer Survivors
This is a qualitative research study involving semistructured interviews and Think-Aloud methodology during completion of a clinical screening tool. All participants will undergo the same semistructured interviews.
- Conditions
- Childhood Cancer, Survivorship, Sexual Dysfunction
- Trial name
- NCT04066218
- Testing
- Interviews
- Where
- 2 sites in United States
- Volunteers
- 24 people
- Sponsor
- University of Colorado, Denver
Brain Neoplasms, Endocrine System Diseases
Assessment of Endocrine and Metabolic Late Effects After Childhood Brain Tumor Treatment
This prospective, single-group interventional study evaluates endocrine and metabolic late effects in survivors of primary brain tumors treated during childhood.
- Conditions
- Brain Neoplasms, Endocrine System Diseases, Metabolic Diseases
- Trial name
- NCT07716579
- Testing
- Study-Specific Endocrine and Metabolic Late-Effects Assessment
- Where
- Slovenia
- Volunteers
- 12 people
- Sponsor
- Institute of Oncology Ljubljana
Cardiovascular Risk, Pediatric Cancer
Vascular Assessment in Adult Survivors of Childhood Cancer
This is an observational study that will collect data from adult survivors of childhood cancer and compare it to data collected from age- and gender-matched controls for the purpose of assessing vascular risk among cancer…
- Trial name
- NCT02010190
- Where
- United States
- Volunteers
- 394 people, healthy volunteers welcome
- Sponsor
- St. Jude Children's Research Hospital
Childhood Cancer Survivors
Lifestyle Medicine Adherence, Mental Wellbeing, and Quality of Life in Pediatric Oncology in Ecuador
Background: Advances in pediatric oncology have significantly improved survival rates; however, many children and adolescents with cancer experience persistent physical and psychological challenges that negatively affect their…
- Trial name
- NCT07490548
- Where
- 4 sites in Ecuador
- Volunteers
- 62 people
- Sponsor
- Universidad de Especialidades Espiritu Santo
Childhood Cancer
Preparing for Life and Academics for Young Childhood Cancer Survivors
The goal of this clinical trial is to test and improve an online program for caregivers of young childhood cancer survivors called the Preparing for Life and Academics for Young Survivors program (PLAY).
- Trial name
- PLAY (NCT06769334)
- Testing
- PLAY Program
- Where
- United States
- Volunteers
- 105 people
- Sponsor
- Nationwide Children's Hospital
Hematopoietic and Lymphoid Cell Neoplasm, Malignant Solid Neoplasm
Mobile Health and Social Media Physical Activity Intervention Among Adolescent and Young Adult Childhood Cancer Survivors, the StepByStep Study
This phase III trial compares a multi-component mobile health and social media physical activity intervention versus wearing a physical activity tracker alone among adolescent and young adult childhood cancer survivors.
- Trial name
- NCT04089358
- Testing
- Educational Intervention, FitBit, Goal Setting
- Where
- 116 sites in United States, Canada
- Volunteers
- 387 people
- Sponsor
- Children's Oncology Group
Survivors of Childhood Cancer
Behavioral Reinforcement Intervention for Greater Health Trajectories After Childhood Cancer (BRIGHT)
Survivors of childhood cancer have a substantially increased risk of long-term health problems in adulthood, including cardiovascular disease, metabolic disorders, psychological morbidity, and impaired health-related quality of…
- Trial name
- BRIGHT (NCT07384286)
- Testing
- Lifestyle Management
- Where
- Sweden
- Volunteers
- 900 people
- Sponsor
- Vastra Gotaland Region
HPV Vaccination
Microvideos for Improving HPV Vaccination Among Childhood Cancer Survivors
This exploratory mixed-methods study aims to examine receipt of treatment and decision-making among rural cancer patients in Utah.
- Trial name
- NCT07648953
- Testing
- Microvideos: HPV Vaccination Education
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- University of Utah