Clinical trials: Childhood Vaccination
Immunization; Infection
Evaluation of Conditional Cash Transfers (CCTs) for Immunization
Like many developing countries, Pakistan faces a public health challenge of low and incomplete immunization rates of children, only 54% of children aged 12 to 24 months are fully immunized, which leaves children susceptible to…
- Trial name
- NCT03355989
- Testing
- Conditional Cash Transfer, SMS Reminder
- Where
- Pakistan
- Volunteers
- 11,197 people, healthy volunteers welcome
- Sponsor
- Interactive Research and Development
Immunization
mHealth-Assisted Conditional Cash Transfers to Improve Timeliness of Vaccinations (D0271)
Vaccination is a cost-effective strategy for conferring immunity against a host of preventable diseases, however, rates of timely childhood vaccinations remain inadequate in resource-limited settings.
- Trial name
- MINT (NCT03252288)
- Testing
- Reminders, Conditional financial transfers
- Where
- Tanzania
- Volunteers
- 412 people
- Sponsor
- Duke University
Vaccine Hesitancy, Childhood Vaccination
Intervention to Promote Childhood Vaccinations and Influence Vaccination Attitudes
This study aims to determine the effect of pregnant women aged 18 years and older who have completed their 28th week of pregnancy and received intervention based on the Health Belief Model, on encouraging childhood vaccinations…
- Trial name
- NCT05425823
- Testing
- Health Belief Model Based Intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Necmettin Erbakan University
Vaccination
Text Message Reminder-Recalls For Early Childhood Vaccination
Although the investigators have reached the Healthy People 2010 goal of 80% coverage among U.S. children 19-35 months of age for the primary immunization series, 20% of children still remain underimmunized.
- Trial name
- NCT01199666
- Testing
- Text message
- Where
- United States
- Volunteers
- 2,586 people
- Sponsor
- Columbia University
Childhood Influenza Vaccination, School-located Influenza Vaccination
School-located Influenza Vaccination Clinics for Adolescents
A cluster-randomized trial (clustering by school) was conducted in Monroe County, NY. Twenty middle and high schools were paired based on several characteristics and randomized within pairs to receiving a school-based influenza…
- Trial name
- SKIPP RCT2 (NCT03137667)
- Testing
- School-located Influenza Vaccination
- Volunteers
- 17,650 people
- Sponsor
- University of California, Los Angeles
Meningococcal Disease
Persistence of Immunogenicity of MenACWY Conjugate Vaccine 5 Years After Childhood Vaccination, and Immune Response to a Booster Dose
In this extension study, V59P20E1, the sponsor was planning to assess 5-year antibody persistence in subjects who received one or two doses of MenACWY conjugate vaccine at 2 to 10 years of age, and to evaluate response to a…
- Trial name
- NCT01823536
- Testing
- Meningococcal (groups A, C, W, and Y) oligosaccharide diphtheria CRM-197 conjugate vaccine
- Where
- 16 sites in United States, Ukraine
- Volunteers
- 465 people, healthy volunteers welcome
- Sponsor
- Novartis Vaccines
Rotavirus Infection
Reactogenicity, Safety and Immunological Efficacy of the Live, Pentavalent Rotavirus Vaccine in Childhood Immunization
The first multicenter prospective, randomized, double-blind, placebo-controlled clinical trial of the pentavalent live vaccine for RVI prevention was conducted in Russia among healthy infants aged 2 months at the time of the…
- Trial name
- NCT05032391
- Testing
- The pentavalent rotavirus vaccine (live attenuated oral, freeze-dried)
- Where
- 2 sites in Russia
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Limited Liability Company Pharm Aid
Evaluating Impact of PACV on Vaccine Hesitancy Among Parents of Newborns
Impact of PACV Administration on Vaccine Hesitancy
Our objective is to assess the impact of administering the PACV to parents of newborns. We also sought to assess the prevalence of vaccine hesitancy among parents of newborns in Houston, TX and to characterize the demographics of…
- Trial name
- NCT04450940
- Testing
- PACV survey
- Volunteers
- 1,705 people, healthy volunteers welcome
- Sponsor
- Baylor College of Medicine
Apnea, Apnea Neonatal
Apnea in Hospitalized Preterm Infants Following the Administration of Routine Childhood Vaccines
A prospective, randomized open-label clinical trial will be conducted from July 2018 to October 2020. Approximately 300 preterm infants will be enrolled across three sites: Duke University Medical Center, the University of North…
- Conditions
- Apnea, Apnea Neonatal, Prematurity
- Trial name
- NCT03530124
- Testing
- PCV13, DTaP, HBV
- Where
- 4 sites in United States
- Volunteers
- 223 people
- Sponsor
- Duke University
Influenza, Human
Childhood Influenza Immunisation Invitation Trial in Schools
This study will investigate whether influenza vaccine uptake by school-age children (in school-based clinics) can be increased by making behavioural-insight informed changes to the invitation process which encourage parents to…
- Trial name
- NCT02883972
- Testing
- Intervention letter, Control letter, Reminder
- Volunteers
- healthy volunteers welcome
- Sponsor
- Public Health England
Cryopyrin-associated Periodic Syndromes, Familial Cold Autoinflammatory Syndrome
Efficacy, Safety and Tolerability of ACZ885 in Pediatric Patients With the Following Cryopyrin-associated Periodic Syndromes: Familial Cold Autoinflammatory Syndrome, Muckle-Wells Syndrome, or Neonatal Onset Multisystem Inflammatory Disease
This trial will provide long-term safety, efficacy and tolerability of ACZ885 in CAPS patients that completed the CACZ885D2307 study
- Conditions
- Cryopyrin-associated Periodic Syndromes, Familial Cold Autoinflammatory Syndrome, Muckle-Wells Syndrome, Neonatal Onset Multisystem Inflammatory Disease
- Trial name
- NCT01576367
- Testing
- ACZ885
- Where
- 12 sites in Belgium, Canada and 5 more
- Volunteers
- 17 people
- Sponsor
- Novartis Pharmaceuticals
Hepatitis B
Adolescents' Response to Hepatitis B Vaccine Booster Dose
The aims of this study are to determine: 1. the degree of immunity against hepatitis B, 2. factors associated with immunity against hepatitis B, 3.
- Trial name
- REACH (NCT01341275)
- Testing
- hepatitis B vaccine
- Where
- 2 sites in United States
- Volunteers
- 400 people
- Sponsor
- Baylor College of Medicine
Breast Feeding, Vaccination Refusal
The Effect of Education Given to Postpartum Women on Their Attitudes Towards Childhood Vaccinations and Breastfeeding
Introduction:Breastfeeding and childhood vaccinations are the two most important public health practices for the healthy growth and development of the newborn.
- Conditions
- Breast Feeding, Vaccination Refusal, Training Group, Sensitivity
- Trial name
- NCT05923320
- Testing
- training
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Amasya University
B-Cell ALL, B-Cell Acute Lymphoblastic Leukaemia
A Multi-site Study to Evaluate the Persistence of Protective Immunity to Routine Childhood Vaccinations in Participants With B-ALL/Ly Who Have Received Blinatumomab
The goal of this observational study is to establish a clear vaccination protocol for pediatric patients (less than 21 years old) who have received treatment for B-cell Acute Lymphoblastic Leukemia/Lymphoma.
- Conditions
- B-Cell ALL, B-Cell Acute Lymphoblastic Leukaemia, B-Cell Lymphoblastic Leukemia, B-Cell Lymphoblastic Leukemia/Lymphoma
- Trial name
- BOOSTER (NCT07422337)
- Where
- 2 sites in United States
- Volunteers
- 300 people
- Sponsor
- Arkansas Children's Hospital Research Institute
Infections, Rotavirus
Vaccine Efficacy Against Rotavirus Diarrhea; Vaccine Given With Routine Childhood Vaccinations in Healthy African Infants
The primary objective of this study is to determine if the GSK Biologicals' human rotavirus (HRV) vaccine (pooled HRV groups) given concomitantly with routine expanded program on immunisation (EPI) vaccinations can prevent severe…
- Trial name
- NCT00241644
- Testing
- Rotarix™
- Where
- 13 sites in Malawi, South Africa
- Volunteers
- 2,089 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Childhood Immunization
Effects of Individual and Group Education on Mothers' Attitudes and Decisions About Childhood Vaccination
This study was planned to determine the effect of face-to-face and group education given to mothers regarding childhood vaccinations on their vaccination attitudes and decisions.
- Trial name
- NCT07324356
- Testing
- Vaccination attitude
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people
- Sponsor
- Istanbul University - Cerrahpasa
Childhood Influenza Vaccination, School-located Influenza Vaccination
Evaluation of the School Kids Influenza Prevention Project
Children whose parents receive text reminders are more likely to be consented to participate in the school located influenza vaccination clinic than children whose parents do not receive text reminders.
- Trial name
- SKIPP (NCT03307642)
- Testing
- Text message notification
- Where
- United States
- Volunteers
- 18,540 people
- Sponsor
- University of Rochester
Fever, Adverse Event Following Immunisation
Safety of RSV Preventive Monoclonal Antibody
This is a prospective, randomized, open-label clinical trial to evaluate the safety of administration of respiratory syncytial virus (RSV) preventive monoclonal antibody and other routine childhood vaccines given simultaneously…
- Trial name
- NCT07158814
- Testing
- Respiratory Syncytial Virus (RSV) Preventive Monoclonal Antibody
- Where
- 6 sites in United States
- Volunteers
- 524 people, healthy volunteers welcome
- Sponsor
- Duke University
Immunization
Immunization Schedule Alert Platform
The ISAP study is investigating the efficacy of SMS messages in improving routine childhood Immunization timeliness and completeness in Nigeria.
- Trial name
- ISAP (NCT03705455)
- Testing
- ISAP SMS
- Where
- Nigeria
- Volunteers
- 1,800 people, healthy volunteers welcome
- Sponsor
- Lifespan Healthcare Resource Limited
Human Papillomavirus
Human Papillomavirus (HPV) Vaccination Among Survivors of Childhood Cancer
This study will focus on the primary objectives: To estimate the prevalence of HPV vaccination among a large cohort of childhood cancer survivors and an acquaintance control group.
- Trial name
- NCT01117389
- Where
- United States
- Volunteers
- 587 people
- Sponsor
- St. Jude Children's Research Hospital