Clinical trials: Children, Adolescents
Type 1 Diabetes
Risk Factors of Metabolic Control in Children and Adolescents With Type 1 Diabetes
Background: Type 1 diabetes is one of the most common chronic illnesses among children and adolescents. Although, intensive medical care is provided for these patients, some of them have poor metabolic control.
- Trial name
- NCT03642470
- Where
- Switzerland
- Volunteers
- 197 people
- Sponsor
- University Children's Hospital, Zurich
Attention Deficit Hyperactivity Disorder
Safety and Efficacy of Switching From a Stimulant Medication to Atomoxetine in Children and Adolescents With ADHD
The purpose of this study is to assess changes in ADHD symptoms and tolerability of medication in children and adolescents switching from a stimulant to atomoxetine.
- Trial name
- NCT00485875
- Testing
- Atomoxetine Hydrochloride
- Where
- United States
- Volunteers
- 62 people
- Sponsor
- Eli Lilly and Company
Acute Lymphoblastic Leukaemia
Allogeneic Stem Cell Transplantation for Children and Adolescents With Acute Lymphoblastic Leukaemia
The ALL SCTped 2012 FORUM is a multinational, multi-centre, controlled, prospective phase III study for the therapy and therapy optimisation for children and adolescents with ALL in complete morphological remission (CR, less than…
- Trial name
- NCT01949129
- Testing
- VP16, TBI, Thiotepa
- Where
- 119 sites in Argentina, Australia and 29 more
- Volunteers
- 1,800 people
- Sponsor
- St. Anna Kinderkrebsforschung
Solid Tumors, Children
A Prospective, Single-arm Clinical Study of Liposomal Mitoxantrone Combination Regimen in the Treatment of Relapsed and Refractory Solid Tumors in Children, Adolescents and Young Adults
The aim of this clinical study is to determine the efficacy and safety of the liposomal mitoxantrone combination regimen in treating relapsed and refractory solid tumors among children, adolescents, and young adults.
- Conditions
- Solid Tumors, Children, Adolescents
- Trial name
- NCT06761417
- Testing
- Mitoxantrone liposome, Capecitabine, Anlotinib
- Where
- China
- Volunteers
- 49 people
- Sponsor
- Cancer Institute and Hospital, Chinese Academy of Medical Sciences
Antibiotic Associated Diarrhea, Clostridium Difficile Infection
Probiotic Lactobacillus Reuteri to Prevent Antibiotic-associated Diarrhea and Clostridium Difficile-related Infections in Hospitalized Children
The purpose of this study is to determine if the daily intake of the probiotic Lactobacillus reuteri prevents antibiotic-associated diarrhoea and related Clostridium difficile infections in children and adolescents.
- Conditions
- Antibiotic Associated Diarrhea, Clostridium Difficile Infection, Gastroenteritis
- Trial name
- AADreuter (NCT01295918)
- Testing
- L reuteri in children on antibiotics
- Where
- 2 sites in Bulgaria
- Volunteers
- 100 people
- Sponsor
- St Marina University Hospital, Varna, Bulgaria
Fish Allergy
Allergy Against Different Species of Fish in Children and Adolescents Allergic to Fish
Study hypothesis: Some children and adolescents with fish allergy can tolerate eating some species of fish Purpose of the study: The purpose of this study is to determine to which degree fish allergic children and adolescents can…
- Trial name
- TRO-FAST (NCT02365168)
- Where
- 2 sites in Norway
- Volunteers
- 44 people
- Sponsor
- University Hospital of North Norway
Sarcoma, Soft Tissue
a Multicenter Clinical Trial for the Treatment of Children and Adolescents With Soft Tissue Sarcoma Stage 4
Phase II Study to evaluate the response on two blocks of topotecan and carboplatin
- Trial name
- NCT00130858
- Testing
- Topotecan, Carboplatin
- Where
- 38 sites in Germany
- Volunteers
- 90 people
- Sponsor
- Cooperative Weichteilsarkom Study Group
Anxiety Disorders, Depressive Disorders
Antidepressant Safety in Kids Study
This study will evaluate the risks and benefits of treatment with a selective serotonin reuptake inhibitor or serotonin-norepinephrine reuptake inhibitor in children and adolescents with a pre-specified anxiety disorder…
- Conditions
- Anxiety Disorders, Depressive Disorders, Eating Disorders, Obsessive Compulsive Disorder
- Trial name
- ASK (NCT00395213)
- Testing
- Selective serotonin reuptake inhibitor (SSRI) and serotonin-norepinephrine reuptake inhibitor (SNRI) medications
- Where
- United States
- Volunteers
- 569 people
- Sponsor
- Duke University
Healthy
Brain Maturation and Sleep
In this study, the investigator evaluates whether there are age-specific diurnal changes in markers of cortical plasticity in children, adolescents and adults.
- Trial name
- BMS (NCT02685891)
- Testing
- Playing tones during deep sleep
- Where
- Switzerland
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University Children's Hospital, Zurich
ADHD - Combined Type
A School-Based Intervention to Improve Social Functioning
Evaluating interventions for children/adolescents with Attention Deficit Hyperactivity Disorder (ADHD) is a field that offers many challenges.
- Trial name
- NCT03313349
- Testing
- Psychotherapy: 1. cognitive therapy 2.family intervention
- Where
- Denmark
- Volunteers
- 32 people
- Sponsor
- Behandlingsskolerne
Bowel Dysfunction
An Evaluation of Navina Mini, a New Trans-anal Irrigation (TAI) Device in Children and Adolescents
The study is designed to deliver further information on clinical benefit, patients' satisfaction, and perception of handling and to confirm safety of Navina Mini when used in children and adolescents.
- Trial name
- NCT06385249
- Testing
- Navina Mini
- Where
- Sweden
- Volunteers
- 27 people
- Sponsor
- Wellspect HealthCare
Parent-Child Relations, Parenting
A Pilot Efficacy and Implementation Study of the Strengths Intervention Project
The purpose of this study is to test a strengths-based intervention to be delivered in a primary care setting with adolescents and a parent.
- Conditions
- Parent-Child Relations, Parenting, Adolescent Behavior, Communication
- Trial name
- SIP (NCT03496155)
- Testing
- Build and Support Your Teen's Strengths
- Where
- United States
- Volunteers
- 174 people
- Sponsor
- Children's Hospital of Philadelphia
High Myopia, Axial Length
Repeated Low-Level Red-Light Therapy Shortens Axial Length
The purpose of this clinical trial is to investigate the incidence and magnitude of axial length shortening after repeated low-level red-light therapy in high myopia children and teenagers.
- Conditions
- High Myopia, Axial Length, Eye Diseases
- Trial name
- NCT05768152
- Testing
- RLRL
- Where
- China
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- The Second People's Hospital of Foshan
Obesity, Childhood, Vitamin D Deficiency
The Changes of Body Composition, Glucolipid Metabolism and Bone Metabolism in Obese Children After Weight Loss
Vitamin D plays a significant role in calcium and phosphorus homeostasis for maintaining structural integrity and function of musculoskeletal system.
- Trial name
- NCT03490448
- Testing
- aerobic exercise and appropriate caloric control
- Where
- China
- Volunteers
- 53 people
- Sponsor
- Xinhua Hospital, Shanghai Jiao Tong University School of Medicine
HIV Infections With Multi Drug Resistant Virus
Safety and Pharmacokinetics Evaluation of Fostemsavir + (OBT) in HIV-1 Infected Children and Adolescents Who Are Failing Their cART and Have Dual- or Triple-class Antiretroviral Resistance
In the SHIELD study, the study sponsor seeks to assess safety, PK and antiviral activity for children and adolescents with dual or triple class resistance.
- Trial name
- NCT04648280
- Testing
- Fostemsavir
- Where
- 8 sites in United States, Brazil and 1 more
- Volunteers
- 60 people
- Sponsor
- PENTA Foundation
Inflammatory Bowel Diseases
The Effect of Exclusion Diet for Crohn's Disease Plus Enteral Nutrition on Children and Adolescents With Crohn's Disease
In this study, children and adolescents with active Crohn's disease are placed in two intervention groups, the first group receives only an exclusion diet and the second group receives an exclusion diet plus formula.
- Trial name
- NCT06353633
- Testing
- formula, exclusion diet
- Volunteers
- 44 people
- Sponsor
- National Nutrition and Food Technology Institute
Type 1 Diabetes Mellitus
Hypoglycemia Fear Affect Autonomic Function, Physical Activity, and Exercise Capacity in Type I Diabetes
This cross-sectional study aims to investigate whether fear of hypoglycemia affects autonomic function, physical activity levels, and exercise capacity in children and adolescents with T1DM.
- Trial name
- HypoFear-T1DM (NCT07527676)
- Testing
- No intervention (observational study)
- Where
- Turkey (Türkiye)
- Volunteers
- 67 people
- Sponsor
- Ordu University
Obesity, Metabolic Disease
Beijing Children and Adolescents Metabolic Syndrome Study (BCAMS Study)
Base on enriched resources from the Metabolic Syndrome cohort in children, a long-term prospective cohort study will be carried out.
- Trial name
- BCAMS (NCT03421444)
- Testing
- No intervention
- Volunteers
- 19,593 people, healthy volunteers welcome
- Sponsor
- Peking Union Medical College Hospital
Pediatric Obesity, Lower Extremity Biomechanics
Training Induced Reduction of Lower-limb Joint Loads During Locomotion in Obese Children
Childhood obesity is one of the most critical and accelerating health challenges throughout the world. It is a major risk factor for developing varus/valgus misalignments of the knee joint.
- Trial name
- NCT02545764
- Testing
- Strength and neuromuscular exercise programme
- Where
- Austria
- Volunteers
- 48 people
- Sponsor
- St. Pölten University of Applied Sciences
Irritability
Psychological Treatments for Youth With Severe Irritability.
Background: When children have severe irritability and temper outbursts, they can be so cranky or angry that it leads to problems at home, in school, and with friends.
- Trial name
- NCT02531893
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- National Institute of Mental Health (NIMH)
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.