Clinical trials: Children, Adolescents
Psychiatric Hospitalization, Mental Disorders
Character Strengths Intervention Among Psychiatrically Hospitalized Youth
Research has shown that identifying and using one's character strengths in new ways decreases depressive symptoms and increases happiness in adults in the general population.
- Conditions
- Psychiatric Hospitalization, Mental Disorders, Child/Adolescent Problems
- Trial name
- NCT02674932
- Testing
- Identifying and Using Signature Strengths, Identifying and Writing Down Coping Skills, Treatment as Usual
- Volunteers
- 153 people
- Sponsor
- University of Michigan
Primary Mediastinal Large B Cell Lymphoma
Intergroup Trial for Children or Adolescents With Primary Mediastinal Large B-Cell Lymphoma: DA-EPOCH-Rituximab Evaluation
Phase II trial to determine the efficacy of Dose Adjusted-EPOCH-Rituximab regimen in children and adolescent with primary mediastinal large B cell lymphoma in terms of event free survival.
- Trial name
- NCT01516567
- Testing
- Etoposide, Doxorubicin, Vincristine, Cyclophosphamide, Rituximab
- Where
- 9 sites in Belgium, Canada and 7 more
- Volunteers
- 47 people
- Sponsor
- Gustave Roussy, Cancer Campus, Grand Paris
ADHD - Attention Deficit Disorder With Hyperactivity, Irritability
Predictors of Improvements in Irritability and Aggression in Children With ADHD Treated With CNS Stimulants
Impulsive Aggression and chronic irritability (IACI) often occur together and are one of the most common reasons children present for behavioral health (BH) care.
- Conditions
- ADHD - Attention Deficit Disorder With Hyperactivity, Irritability, Aggression Childhood
- Trial name
- NCT06871488
- Testing
- CNS Stimulant, CNS Stimulant open label first phase
- Where
- United States
- Volunteers
- 136 people
- Sponsor
- Milton S. Hershey Medical Center
Non-Alcoholic Fatty Liver Disease
Effect of Indo-Mediterranean Diet on Hepatic Steatosis and Fibrosis in NAFLD Children
NAFLD encompasses the entire spectrum of Fatty liver disease in individuals without significant alcohol consumption, ranging from fatty liver to steatohepatitis to cirrhosis.
- Trial name
- NCT05073588
- Testing
- Indo Mediterranean diet, Calorie restricted diet
- Where
- India
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Institute of Liver and Biliary Sciences, India
Psychosis
Psychosis Associated With Methylphenidate in Children and Adolescents
perform a study in VigiBase® to assess if methylphenidate was associated with an over-reporting of psychosis including hallucinations in children and adolescents and to characterize those psychosis.
- Trial name
- NCT06518330
- Testing
- Intake of Methylphenidate
- Where
- France
- Volunteers
- 46,233 people
- Sponsor
- University Hospital, Caen
Obsessive-Compulsive Disorder
Smart Sensory Technology in Psychotherapy for Pediatric OCD
Telemedicine interventions enable the improvement of behavioral state-of-the-art treatment of OCD, as therapy can be delivered in the patients' immediate home environment, allowing for more valid symptom actualization.
- Trial name
- SSTeP-KiZ (NCT05291611)
- Testing
- Online-based Cognitive-behavioral Therapy for OCD
- Where
- Germany
- Volunteers
- 20 people
- Sponsor
- University Hospital Tuebingen
Adolescents, Mobile Application
The Effect of Mobile Application Supported Health Promotion Program on Obesity of Adolescents
The aim of the study is to evaluate the effectiveness of the Child Obesity Program (COP), which is a school-based, parent-based, weight management program aimed mobile application at preventing overweight and obesity in childhood.
- Conditions
- Adolescents, Mobile Application, School Health, Physical Activity
- Trial name
- obesity (NCT06427525)
- Testing
- Mobile application-based adolecent obesity education
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Epilepsy
Pharmacokinetics, Efficacy and Tolerability of BIA 2-093
The purpose of this study is to characterize the pharmacokinetics of Eslicarbazepine acetate in children and adolescents with epilepsy.
- Trial name
- NCT02170064
- Testing
- BIA 2-093 (Eslicarbazepine acetate)
- Where
- Romania
- Volunteers
- 35 people
- Sponsor
- Bial - Portela C S.A.
Hepatoblastoma
A Prospective Multicenter Clinical Study of SCCG Protocol and ctDNA 5hmc in Predicting the Chemotherapy Sensitivity and Monitoring the Recurrence and Metastasis of Hepatoblastoma in Children and Adolescents
Hepatoblastoma is the most common malignant liver tumor in infants and preschool children, comprising 65% of pediatric liver malignancies in those under 15, with its incidence on the rise in recent years [1].
- Trial name
- NCT07300449
- Testing
- Very low-risk group, Low-risk group, Intermediate-risk group
- Where
- 2 sites in China
- Volunteers
- 100 people
- Sponsor
- Sun Yat-sen University
Autism Spectrum Disorder
Sleep, Mood, and Quality of Life Issues in ASD Adolescents and Adults.
Autism Spectrum Disorder (ASD) presents unique challenges, particularly in sleep, mood, and quality of life for adolescents and adults.
- Trial name
- NCT07033078
- Where
- Taiwan
- Volunteers
- 166 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
End Stage Renal Disease on Dialysis
Pulmonary Function Tests in Children and Adolescents With End Stage Renal Disease On Regular Hemodialysis
to study pulmonary function tests in children with ESRD on regular HD and its correlation with dialysis duration and other various risk factors
- Trial name
- NCT06106438
- Volunteers
- 40 people
- Sponsor
- Assiut University
Marijuana Abuse
Efficacy of Contingency Management in the Treatment of Adolescents With Cannabis Use Disorders
Cannabis use among Spanish adolescents has been increasing in the last decade. It has been related to poor school achievement, delinquency, substance use and psychiatric disorders.
- Trial name
- NCT00878852
- Testing
- Standard treatment, Standard Treatment Plus Contingency Management Program
- Where
- Spain
- Volunteers
- 30 people
- Sponsor
- Hospital Clinic of Barcelona
Pre-Diabetes
Detection of Pre-Diabetes in Overweight and Obese Children
Descriptive cross section study To detect prediabetes in overweight and obese children and adolescents in Assiut Governorate and to find out the possible risk factors.
- Trial name
- NCT06117358
- Volunteers
- 100 people
- Sponsor
- Assiut University
Childhood Obesity
Motivational Interviewing for Weight Loss
The investigators studied the effect of motivational interviewing (MI) on self-efficacy, health behaviors, and health outcomes in overweight children and adolescents (ages ranging from 10 to 18 years).
- Trial name
- NCT01246349
- Testing
- Motivational Interviewing (Treatment Group), Social Skills Training (Control Group)
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- The Hospital for Sick Children
Pediatric Bipolar Disorder
Invega (Paliperidone) for the Treatment of Mania in Children and Adolescents Ages 6-17 With Bipolar Disorder
This will be an 8-week open-label trial, using daily doses of paliperidone (Invega) in the treatment of children and adolescents who meet DSM-IV criteria of Bipolar I, Bipolar II, or Bipolar Spectrum Disorder.
- Trial name
- NCT00592358
- Testing
- paliperidone
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Massachusetts General Hospital
Autism Spectrum Disorder, Transition
Evaluating the Efficacy and Effectiveness of SCOPE - RCT
The study will entail an evaluation of the feasibility, acceptability, efficacy and effectiveness of SCOPE coach supported internet-delivered psychoeducative program using a randomized controlled design in a clinical health care…
- Trial name
- SCOPERCT (NCT03665363)
- Testing
- SCOPE, Self-study
- Where
- Sweden
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Myopia
Effectiveness of Myopia Control Interventions : A Comparison of Myopia Control in European Children, Adolescents and Young Adults With Defocus Incorporated Multiple Segments (DIMS) and Highly Aspherical Lenslets (HAL) Spectacles, Atropine, Lenses and Combined Treatments
The prevalence of myopia and its complications has risen considerably in recent decades, particularly among children and teenagers.
- Trial name
- NCT07120165
- Testing
- Demographic data collection, Ophthalmological history, Ophthalmological data at each examination
- Where
- France
- Volunteers
- 114 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Bereavement
Long-term Consequences of Bereavement in Children, Adolescents and Young Adults
The purpose of this study is to examine how the death of a parent as a child, adolescent or young adult affects health and psychosocial wellbeing in adult life and to evaluate the impact in adult life of counseling to children…
- Trial name
- NCT01453699
- Where
- Denmark
- Volunteers
- 1,225,660 people, healthy volunteers welcome
- Sponsor
- Danish Cancer Society
Autistic Disorder, Child Development Disorders, Pervasive
Social Skills and Anxiety Reduction Treatment for Children and Adolescents With Autism Spectrum Disorders
This study will develop and test a treatment aimed at reducing anxiety in social situations for children and adolescents with autism spectrum disorders.
- Trial name
- NCT00926471
- Testing
- Cognitive Behavioral Therapy (CBT) Program
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Virginia Polytechnic Institute and State University
Type 1 Diabetes
Study of Insulin Therapy Augmented by Real Time Sensor IN Type 1 Children and Adolescents (START-IN!)
Glycemic control in children and adolescent with type 1 diabetes remains inadequate, exposing them to the risk of vascular complications in adulthood.
- Trial name
- START-IN (NCT00949221)
- Testing
- monitor Paradigm 754 VEO, MINILINK Real Time, Medtronic, CE
- Where
- France
- Volunteers
- 150 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
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