Clinical trials: Children, Adolescents
Acquired Brain Injury
Exploring the Use of the Cognitive Orientation to Daily Occupational Performance Approach (CO-OP) With Children, Teenagers and Young Adults With Executive Functions Deficits Following Severe Acquired Brain Injury
Acquired brain injury (ABI) in childhood are the cause of disabling motor, cognitive and behavioural disorders, with severe consequences on the later development of autonomy and learning, with long-term repercussions on…
- Trial name
- REFECO-OP (NCT04560777)
- Testing
- CO-OP intervention
- Where
- 2 sites in France
- Volunteers
- 12 people
- Sponsor
- Hopitaux de Saint-Maurice
Autism Spectrum Disorder
A Study to Evaluate Scales for Repetitive and Restricted Behaviors in Children, Adolescents, and Adults With Autism Spectrum Disorder (ASD)
This is a non-drug study seeking to characterize different scales to measure repetitive and restrictive behaviors in different ASD sub-populations over time. This study will also explore the use of digital biomarkers.
- Trial name
- NCT03611075
- Testing
- No Intervention
- Where
- 18 sites in United States, Canada and 1 more
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- Hoffmann-La Roche
Adolescent Idiopathic Scoliosis
Effect of VRGs on Changing the Center of Gravity Location in AIS
The purpose of this clinical trial is to examine the effect of virtual reality games (VRG) on changing the location of the center of gravity in children with adolescent idiopathic scoliosis (AIS).
- Trial name
- NCT05901792
- Testing
- Virtual Reality Games, Waiting List
- Where
- Turkey (Türkiye)
- Volunteers
- 28 people
- Sponsor
- Istanbul University - Cerrahpasa
Anxiety Disorders
Fluoxetine for Anxious Children
The purpose of this study is to see if it is safe and effective to use fluoxetine to treat children and adolescents with Generalized Anxiety Disorder (GAD).
- Trial name
- NCT00000381
- Testing
- Fluoxetine
- Sponsor
- University of Pittsburgh
Social Anxiety Disorder, Separation Anxiety Disorder
Stepped Versus Stratified Care for Anxiety Disorders in Youth
The goal of this clinical trial is to compare stepped care to stratified care as overall healthcare models for children and adolescents aged 8-17 with anxiety disorders.
- Conditions
- Social Anxiety Disorder, Separation Anxiety Disorder, Specific Phobia, Panic Disorder
- Trial name
- NCT06942429
- Testing
- Internet-delivered cognitive-behavioral therapy, Personalized in-person cognitive-behavioral therapy
- Where
- Sweden
- Volunteers
- 556 people
- Sponsor
- Region Skane
Hypertriglyceridemia
Fish Oil Study for High Triglyceride Levels in Children
High triglyceride levels are increasingly recognized in children, particularly those who are overweight. There are no studies of treatment of high triglycerides in children and adolescents.
- Trial name
- NCT00915902
- Testing
- Omega-3-acid ethyl esters
- Where
- 3 sites in United States
- Volunteers
- 42 people
- Sponsor
- Babu Balagopal
Anxiety Disorders
Investigating the Effects of Parent Component to Cognitive Behavior Therapy (CBT) for Youth With Anxiety Disorders
Investigation is designed to determine whether the gold standard for treating anxious youth is enhanced by teaching parents to become their anxious child's CBT coach.
- Trial name
- NCT02160444
- Testing
- CBT plus Parent as CBT Coach Training
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- University of Texas at Austin
Dup15Q Syndrome
A Phase II Study of Basmisanil in Children and Adolescents With Dup15q Syndrome
The primary goal of this Phase 2 clinical trial is to determine the effects of a selective negative allosteric modulator (NAM) of GABAA α5 receptor, Basmisanil (NTX-1511), on brain wave (EEG) characteristics in children and…
- Trial name
- NCT07846215
- Testing
- Basmisanil
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Newleos Therapeutics, Inc.
Cognitive Deficit in Attention, Executive Dysfunction
Maternal Choline Supplementation and Offspring Cognition in Adolescence
The goal of this 13-year follow up of a randomized control trial is to study the effect of maternal choline supplementation on offspring cognition in adolescence.
- Conditions
- Cognitive Deficit in Attention, Executive Dysfunction, Emotional Regulation
- Trial name
- CholTeens (NCT05859126)
- Testing
- Maternal Choline Supplementation 930 mg/d, Maternal Choline Supplementation 480 mg/d
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Cornell University
Attention-Deficit/Hyperactivity Disorder, Comorbid Dyslexia
Treatment With Atomoxetine Hydrochloride in Children and Adolescents With ADHD
The purpose of this study is to assess the efficacy and safety of atomoxetine administered once daily in the treatment of children and adolescents with ADHD and comorbid dyslexia.
- Trial name
- NCT00191048
- Testing
- Atomoxetine
- Where
- 8 sites in United States
- Volunteers
- 105 people
- Sponsor
- Eli Lilly and Company
Non-verbal Learning Disorder, Autism Spectrum Disorder
Natural Treatments for the Management of Emotional Dysregulation in Youth With Non-verbal Learning Disability (NVLD) and/or Autism Spectrum Disorders (ASD)
This study consists of a 6-week, open-label, randomized clinical trial study to compare efficacy and tolerability of the natural treatments omega-3 fatty acids, inositol, and N-acetylcysteine (NAC) in the treatment of mood…
- Conditions
- Non-verbal Learning Disorder, Autism Spectrum Disorder, Autism
- Trial name
- NCT03757585
- Testing
- Open-label Treatment with Omega-3 Fatty Acids + Inositol, Open-label Treatment with N-acetylcysteine
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- Massachusetts General Hospital
Diabetes Mellitus, Type 1
Neurocognitive Performance During Hyperglycemia , and Brain Tissue Integrity in Youth With Type 1 Diabetes and in Healthy
Study population : 90 Participants. 60 with T1DM , and 30 healthy controls. T1DM patients will be recruited by research publication in diabetes mellitus forums. Baseline visit: informed consent signing.
- Trial name
- T1DM (NCT02923323)
- Testing
- MRI including DTI , EEG, CGMS, Neurocognitive tests
- Where
- Israel
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Assaf-Harofeh Medical Center
Atopic Dermatitis
A Study of Baricitinib (LY3009104) in Children and Adolescents With Atopic Dermatitis
The reason for this study is to see if the study drug called baricitinib works and is safe in children and teenage participants with atopic dermatitis.
- Trial name
- BREEZE-AD-PEDS (NCT03952559)
- Testing
- Baricitinib, Topical corticosteroid
- Where
- 78 sites in Argentina, Australia and 15 more
- Volunteers
- 516 people
- Sponsor
- Eli Lilly and Company
Obesity, Atherosclerosis
Endothelial Dysfunction in Obese Children
The purpose of this study is to objectify the effect of diet and exercise on early markers of atherosclerosis in obese children.
- Trial name
- EDOC (NCT01461226)
- Testing
- Exercise training, Usual care
- Where
- 3 sites in Belgium
- Volunteers
- 61 people
- Sponsor
- University Hospital, Antwerp
Cystic Fibrosis, Cystic Fibrosis in Children
Program Of Exercises During The Hospitalization Of Children And Adolescents With Cystic Fibrosis
The objective of this study was to evaluate the effect of a physical exercise program on the functional capacity of children and adolescents with cystic fibrosis hospitalized at the Hospital de Clínicas of Porto Alegre (HCPA)…
- Conditions
- Cystic Fibrosis, Cystic Fibrosis in Children, Cystic Fibrosis Pulmonary Exacerbation, Cystic Fibrosis With Exacerbation
- Trial name
- NCT03273959
- Testing
- Exercise protocol
- Where
- Brazil
- Volunteers
- 50 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Vision Disorders
Unmet Needs, Barriers and Facilitators to Vision Services for Children and Adolescents With Special Vision
Children and adolescents with special needs, compared to those with general development, have a much higher incidence of visual impairments (10.5% vs. 0.16%).
- Trial name
- NCT05921240
- Testing
- observational study, no intervention
- Where
- Taiwan
- Volunteers
- 164 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Drug Hypersensitivity
A Study to Assess the Hypersensitivity to TAK-880 Compared to Gammagard S/D in Blood of Children, Teenagers and Adults
The aim of this study is to find out whether TAK-880 creates hypersensitivity reactions compared to Gammagard S/D by testing blood taken from participants who have a higher risk of becoming hypersensitive to immunoglobulin…
- Trial name
- NCT05269082
- Testing
- No intervention
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- Takeda
Asthma
Anti-Inflammatory Reliever South Africa
This is a Phase 3 single-centre open label randomised controlled trial with two equal sized groups to assess the efficacy of budesonide/formoterol 80/4.5 (6-11 years) and 160/4.5 (12-18 years) compared to the standard of care in…
- Trial name
- AIRSA001 (NCT06429475)
- Testing
- Budesonide/formoterol, standard of care
- Where
- 2 sites in South Africa
- Volunteers
- 1,038 people
- Sponsor
- University of KwaZulu
Autism Spectrum Disorders
Brain Imaging of Intranasal Oxytocin Treatment in Autism
This is a 4 part study: Phase 1a. -functional magnetic resonance imaging (fMRI) ( with oxytocin 24 IU vs. placebo = oxytocin 0 IU) - funded by grant #U54 HD079124-01, Phase 1b-eye-tracking(oxytocin 24 IU vs.
- Trial name
- NCT01945957
- Testing
- Oxytocin
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- University of North Carolina, Chapel Hill
Dental Anxiety
Children and Adolescents With Dental Anxiety - Randomized Controlled Study of Cognitive Behavioral Therapy
The purpose of this study is to determine whether cognitive behaviour therapy is effective in the treatment of children and adolescents with dental anxiety.
- Trial name
- NCT01798355
- Testing
- Cognitive Behavioral Therapy, Treatment As Usual
- Where
- Sweden
- Volunteers
- 30 people
- Sponsor
- Karolinska Institutet
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.