Clinical trials: Children, Adolescents
Epilepsy (Treatment Refractory), Epilepsy in Children
OPM MEG in Pre-surgical Mapping for Patients With Epilepsy
Magnetoencephalography, or "MEG", is a brain-scanning method which has been available for many years. It is used in the UK and worldwide to help patients with epilepsy, who need surgery to resolve their seizures.
- Conditions
- Epilepsy (Treatment Refractory), Epilepsy in Children, Epilepsy in Youth
- Trial name
- NCT07378397
- Where
- United Kingdom
- Volunteers
- 20 people
- Sponsor
- Aston University
Mental Health Issue, Family Relations
An Evaluation of a Family Counseling Intervention ("Tuko Pamoja") in Kenya
The purpose of this study is to evaluate a family counseling intervention, entitled "Tuko Pamoja" (Translation "We are Together" in Kiswahili).
- Conditions
- Mental Health Issue, Family Relations, Family Conflict, Child Mental Disorder
- Trial name
- C0058 (4C) (NCT06417918)
- Testing
- Tuko Pamoja, "We are Together" in Kiswahili
- Where
- Kenya
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Duke University
Sedentary Behavior, Affect
Effects of Multi-day Interruptions in Sitting on Type 2 Diabetes-relevant Outcomes in Children
The overall objective of this in-lab randomized controlled trial is to test the efficacy of multi-day interruptions in sedentary behavior vs.
- Conditions
- Sedentary Behavior, Affect, Metabolic Disturbance, Anxiety
- Trial name
- NCT04469790
- Testing
- SIT+WALK, EX
- Where
- United States
- Volunteers
- 188 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Child Development
Randomized Trial of the Effects of Musical Training on Child Development in the Venezuela Orchestra Program (El Sistema)
This study evaluates Venezuela's National System of Child and Youth Orchestras, better known as "El Sistema".
- Trial name
- NCT02369315
- Testing
- Treatment (Invited entry 2012), Control (Invited entry 2013)
- Volunteers
- 2,914 people
- Sponsor
- Inter-American Development Bank
Substance Use, Parenting
Feasibility Study of a Web-based Program to Help Parents of Middle School Students Effectively Communicate With Their Children About Substance Use
The goal of this study is to test the feasibility of a web-based program for parents of middle school aged students. 286 parents and their child in 6th, 7th, or 8th grade will be asked to each complete two online questionnaires…
- Conditions
- Substance Use, Parenting, Communication
- Trial name
- NCT05900115
- Testing
- Media Ready Parent, Active Control Program
- Where
- United States
- Volunteers
- 576 people, healthy volunteers welcome
- Sponsor
- Innovation Research & Training
Flexible Flatfoot
Early Warning and Intervention Mechanism of Foot Health Risk in Children and Adolescents
This clinical study was a prospective intervention study. The growth and development parameters and kinematic parameters of 120 children were planned to be collected for an observational study, and then the sensors were used to…
- Trial name
- NCT06581978
- Testing
- Whole-Body Vibration Intervention, Exercise Intervention Group
- Where
- China
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Nanfang Hospital, Southern Medical University
Facial Expression
Recording Facial Expressions to Assess Taste in Children and Teenagers
The study is designed to see if, after tasting specific things, whether a child's facial pattern and voice pattern can determine the difference in something that has a sweet taste, no taste, and a bitter taste.
- Trial name
- NCT02923908
- Testing
- Noldus Facereader 7, Voice Recording, 5-Point Facial Hedonic Scale
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Arkansas Children's Hospital Research Institute
Endstage Renal Disease
Randomized Multicenter Cross-over Study to Compare the Effect of Physioneal 35 to 40 on the Protein Metabolism
The purpose of this study is to demonstrate an increase in protein metabolism during treatment with Physioneal 35® (containing lactate 10 mmol/l, calcium 1.75 mmol/l) compared to treatment with Physioneal 40® (containing lactate…
- Trial name
- NephropaedPD01 (NCT00776191)
- Testing
- Physioneal 35, Physioneal 40
- Where
- 5 sites in Germany
- Volunteers
- 5 people
- Sponsor
- University of Erlangen-Nürnberg Medical School
Bipolar Disorder
Open-Label Study of N-Acetylcysteine in Children and Adolescents 5-17 With Bipolar Spectrum Disorders
Children between the ages of 5-17 years old who have or display symptoms of emotional dysregulation (explosiveness, mood swings, irritability, and/or violent behavior) are invited to participate in a 12-week research study to…
- Trial name
- NCT02357290
- Testing
- Open-label Treatment with N-Acetylcysteine
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Massachusetts General Hospital
Chronic Hepatitis B
Study of Efficacy and Safety, Tolerability and Pharmacokinetics of Telbivudine in Children and Adolescents With Compensated Chronic Hepatitis B Virus Infection
The purpose of the study was to assess the efficacy and safety of telbivudine at a dose of 20 mg/kg up to a maximum of 600 mg q.d.
- Trial name
- NCT02058108
- Testing
- Telbivudine
- Where
- 29 sites in Bulgaria, Greece and 5 more
- Volunteers
- 53 people
- Sponsor
- Novartis Pharmaceuticals
Epilepsy
STEP: Enhanced Physical Activity in Children and Youth With Epilepsy
Epilepsy is common in childhood. Children with epilepsy are at increased risk of impaired health, functioning, psychological well-being, and quality of life.
- Trial name
- STEP (NCT01550874)
- Testing
- Physical activity behavior-change counselling
- Where
- 2 sites in Canada
- Volunteers
- 122 people
- Sponsor
- McMaster University
Pain
Comparing Gabapentin and Amitriptyline for the Treatment of Neuropathic Pain in Children and Adolescents
The objective of the study is to compare the efficacy of gabapentin and amitriptyline for treating neuropathic pain in children in a randomized controlled trial.
- Trial name
- NCT00312260
- Testing
- Gabapentin, Amitriptyline
- Where
- Canada
- Volunteers
- 34 people
- Sponsor
- The Hospital for Sick Children
Ulcerative Colitis, Ulcerative Colitis Chronic
A Master Protocol (AMAZ): A Study of Mirikizumab (LY3074828) in Pediatric Participants With Ulcerative Colitis or Crohn's Disease (SHINE-ON)
The main purpose of this study is to evaluate the long-term efficacy of mirikizumab in pediatric participants with ulcerative colitis (UC) or Crohn's disease (CD).
- Conditions
- Ulcerative Colitis, Ulcerative Colitis Chronic, Inflammatory Bowel Diseases, Crohn's Disease
- Trial name
- SHINE-ON (NCT04844606)
- Testing
- Mirikizumab
- Where
- 69 sites in United States, Austria and 14 more
- Volunteers
- 150 people
- Sponsor
- Eli Lilly and Company
Autism
Learning Enhancement Through Neurostimulation in Autism
This study will examine whether brain stimulation paired with social skills learning can help teenage boys with autism learn how to make and keep friends. Brain stimulation can enhance learning in some people.
- Trial name
- LENS (NCT02998684)
- Testing
- Active Transcranial Direct Current Stimulation, PEERS Social Skills Training
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Fragile X Syndrome (FXS), Autism Spectrum Disorder
Group CBT in Adolescents With Fragile X Syndrome and in Adolescents With Autism Spectrum Disorder
Fragile X Syndrome (FXS) is a rare genetic syndrome, caused by a mutation in the FMR1 gene located on the X chromosome. It is considered the leading hereditary cause of intellectual disability (ID) and the primary cause of Autism…
- Trial name
- NCT06677866
- Testing
- Cognitive behavioral therapy, Waiting List
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- Bambino Gesù Hospital and Research Institute
Acute Febrile Illness
Advancing Access to Diagnostic Innovation Essential for UHC and AMR Prevention
This study aims to evaluate clinical outcomes and antibiotic prescription patterns following the use of diagnostic algorithms, point of care (PoC) rapid diagnostic tests, and behaviour change interventions in cases of acute…
- Trial name
- Accelerator (NCT04081051)
- Testing
- diagnostic algorithm+Point of care rapid diagnostic tests+ Behavior change ( assessed together as a single package of interventions)
- Where
- 8 sites in Burkina Faso, Ghana and 3 more
- Volunteers
- 17,294 people
- Sponsor
- Foundation for Innovative New Diagnostics, Switzerland
Dermatitis, Contact
Clinical Evaluation of T.R.U.E. TEST in Children and Adolescents
Open, prospective, single-site, non-randomized study of the efficacy and safety of T.R.U.E. TEST allergens in children and adolescents ages 6-18.
- Trial name
- NCT00795951
- Testing
- T.R.U.E. Test
- Where
- United States
- Volunteers
- 102 people
- Sponsor
- Allerderm
Normal Values of Peripheral Nerves in Healthy Children
Ultrasonographic Reference Values for Peripheral Nerves in Children
The purpose of this clinical trial is to assess normal values of the cross-sectional area of peripheral nerves and nerve roots in children and adolescents between 2 and 18 years.
- Trial name
- NCT02570802
- Testing
- Ultrasonographic examination
- Where
- Switzerland
- Volunteers
- 255 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Schizophrenia, Psychotic Disorders
Dimensional and Developmental Profiles of Psychosis in Children and Adolescents
Five collaborating sites in France will study the broad spectrum of schizophrenia in children and adolescents. Patients will be studied with diagnostic interviews, developmental histories, dimensional clinical ratings…
- Trial name
- PSYDEV (NCT04370730)
- Testing
- clinical, neuroimaging and DNA assessments
- Where
- 6 sites in France
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Binge Eating Disorder, Binge Eating
Effectiveness of a 10-week Multicomponent Intervention Combined With Parent Education on Binge Eating Behavior in Children and Adolescents
The main purpose is to investigate the effectiveness of a 10-week multicomponent camp intervention to reduce BE behavior in children and adolescents and explore in a randomized controlled setting if a parent-based…
- Conditions
- Binge Eating Disorder, Binge Eating, Loss of Control Eating, Overweight , Obesity
- Trial name
- STOB (NCT07301541)
- Testing
- A 10-week multicomponent camp intervention for children, A BED intervention for parents
- Where
- 2 sites in Denmark
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
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