Clinical trials: Children, Adolescents
Cerebral Palsy
Adaptive Dance Exercise Program on Trunk Control, Balance and Functional Mobility in Cerebral Palsy
The human body needs a system to control and coordinate its action plan in order to perform an effective action. This system works irregularly or inappropriately in people with Cerebral Palsy (CP).
- Trial name
- NCT04884724
- Testing
- Adaptive Dance Exercise Program
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 27 people
- Sponsor
- Istanbul University - Cerrahpasa
Intraoperative Neurophysiological Monitoring, Pain Management
Effect of a Bolus of Clonidine Systemically Administered on the Excitability of the Spinal Motoneurons of the Lower Extremity
The purpose of this study is to assess the effect of IV clonidine administration on lower limb spinal motoneuron excitability during standardized total intravenous anesthesia (propofol and remifentanil).
- Trial name
- EXCICLON (NCT02592915)
- Testing
- Clonidine hydrochloride, Single bolus of physiologic sodium chloride serum administered IV after induction and obtaining a stable anaesthetic level
- Where
- Belgium
- Volunteers
- 40 people
- Sponsor
- Queen Fabiola Children's University Hospital
COVID-19
A Study to Evaluate the Safety and Immunogenicity of Ad5-nCoV and Ad5-nCoV-IH in CoronaVac Immunized Children and Adolescents
This is a multicenter, randomized, and open-label study to evaluate the immune responses and safety profiles of children aged 6-12 years and adolescents aged 13-17 years receiving Ad5-nCoV (intramuscular injection) or Ad5-nCoV-IH…
- Trial name
- NCT05169008
- Testing
- Recombinant Novel Coronavirus Vaccine (Adenovirus Type 5 Vector), Recombinant COVID-19 vaccine (adenovirus type 5 vector) for Inhalation (Ad5-nCoV-IH)
- Where
- 2 sites in Chile
- Volunteers
- 91 people, healthy volunteers welcome
- Sponsor
- CanSino Biologics Inc.
Bipolar Disorder, Bipolar I Disorder
Children's Bipolar Network Treatment Trial I
This is a naturalistic treatment and follow-up study of youth with bipolar spectrum disorders (BSDs) across four US sites of The Childhood Bipolar Network (CBN).
- Conditions
- Bipolar Disorder, Bipolar I Disorder, Bipolar II Disorder, Other Specified Bipolar and Related Disorder
- Trial name
- CBN (NCT05427123)
- Testing
- Medication or psychosocial treatment
- Where
- 4 sites in United States
- Volunteers
- 80 people
- Sponsor
- University of California, Los Angeles
Type 1 Diabetes Mellitus
Impact of ELKa, the Toolset for Food Exchanges Calculation on Metabolic Control in Pediatric Diabetic Patients.
ELKa system is an advanced toolset which helps performing calculation of carbohydrate (CHO) and fat/protein (FP) exchanges. It consists of ELKa software including database of various meals and nutrients and ELKaPlus digital…
- Trial name
- NCT02194517
- Testing
- ELKa
- Where
- Poland
- Volunteers
- 106 people
- Sponsor
- Medical University of Warsaw
Hematologic Diseases, Acute Leukemia in Remission
Vorinostat for Graft vs Host Disease Prevention in Children, Adolescents and Young Adults Undergoing Allogeneic Blood and Marrow Transplantation
The purpose of this study is to determine the recommended phase 2 dose of the drug Vorinostat in children, adolescents and young adults following allogeneic blood or marrow transplant (BMT) and determine whether the addition of…
- Conditions
- Hematologic Diseases, Acute Leukemia in Remission, Chronic Myelogenous Leukemia - Chronic Phase, Chronic Myelogenous Leukemia, Accelerated Phase
- Trial name
- NCT03842696
- Testing
- Vorinostat, Blood and Marrow Transplant (BMT), Tacrolimus (or cyclosporine)
- Where
- 7 sites in United States
- Volunteers
- 43 people
- Sponsor
- University of Michigan Rogel Cancer Center
Anxiety Disorders and Symptoms, Depressive Symptoms
Transdiagnostic, Indicated Preventive Intervention for Adolescents At High Risk of Emotional Problems W/Add-On Modules
PROCARE is a preventive intervention that has shown its effectiveness in selective prevention to reduce young people's risk of developing emotional problems.
- Trial name
- PROCARE-I+ (NCT06350760)
- Testing
- Active control condition, PROCARE-I+ 8-session
- Where
- 3 sites in Spain
- Volunteers
- 139 people, healthy volunteers welcome
- Sponsor
- University of Jaén
Depression, Bipolar Disorder
Bupropion SR for Major Depression and Depression NOS in Children and Adolescents With Bipolar Disorder
This is an 8-week open label study of bupropion SR in the treatment of youth with bipolar depression with adequate mood stabilization.
- Trial name
- NCT00181896
- Testing
- bupropion SR
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Massachusetts General Hospital
Social Skills, Transition
The ASSET Program for Youth With ASD
The purpose of this project is to evaluate the effectiveness of a work-related social skills training intervention for transition-age youth with Autism Spectrum Disorder (ASD; ages 14-22) that is designed to improve social…
- Conditions
- Social Skills, Transition, Autism Spectrum Disorder, Confidence, Self
- Trial name
- ASSET (NCT06535191)
- Testing
- Assistive Soft Skills and Employment Training (ASSET)
- Where
- United States
- Volunteers
- 85 people
- Sponsor
- Michigan State University
Myopia
A Real-world Study of 650nm Low-intensity Single-wavelength Red Light for Children and Adolescents
To evaluate the efficacy and safety of 650nm low-level red-light irradiation for myopia control and prevention in children under less restrictive conditions than randomized controlled trials.
- Trial name
- NCT05832723
- Testing
- 650 nm low-level red-light
- Where
- China
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Beijing Tongren Hospital
Aggressive Behavior
Brain Changes in Adolescents While Imagining and Observing Aggressive Behavior
This study will use functional magnetic resonance imaging (fMRI) to examine what happens in the brains of adolescents when they are exposed to violent media and how imagining aggressive behavior affects brain function.
- Trial name
- NCT00267891
- Where
- United States
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Suicidal Ideation, Suicidal and Self-injurious Behavior
A Comparison of Two Brief Suicide Prevention Interventions Tailored for Youth on the Autism Spectrum
Rates of suicide have increased significantly over the past two decades, particularly among youth. Compared to the general population, autistic people are significantly more likely to think about suicide, attempt suicide, and die…
- Conditions
- Suicidal Ideation, Suicidal and Self-injurious Behavior, Suicide, Autism Spectrum Disorder
- Trial name
- NCT05398250
- Testing
- Safety Planning Intervention tailored for Autistic Individuals, Safety Planning Intervention Tailored for Autistic Individuals Plus Structured Follow-Up Contacts
- Where
- 5 sites in United States
- Volunteers
- 1,665 people
- Sponsor
- University of North Carolina, Chapel Hill
Mental Disorders Diagnosed in Childhood
Psychosocial Training for Pediatric Health Care Providers
This study will provide psychosocial training to general health care providers to help them provide better care to children with mental health problems.
- Trial name
- NCT00070876
- Testing
- Mental health communication skills training
- Where
- United States
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Attention Deficit Hyperactivity Disorder
Study of Broader Efficacy of Atomoxetine in the Treatment of ADHD in Children/Adolescents
To test the hypothesis that children/adolescents with ADHD, who are treated with atomoxetine hydrochloride in comparison to standard current therapies have greater improvements in their quality of life.
- Trial name
- NCT00191659
- Testing
- Atomoxetine Hydrochloride
- Where
- United Kingdom
- Volunteers
- 200 people
- Sponsor
- Eli Lilly and Company
Autism Spectrum Disorder
ML-004 Open-Label Extension Study in Adults and Adolescents With Autism Spectrum Disorders (ASD)
ML-004-003 is a multi-center, open-label extension study that will enroll approximately 120 adolescent and adult subjects with ASD that have completed study ML-004-002.
- Trial name
- NCT05889273
- Testing
- ML-004 (IR)/(ER) tablet
- Where
- 21 sites in United States, Australia and 1 more
- Volunteers
- 120 people
- Sponsor
- MapLight Therapeutics
Emotional Problem, Mental Health Issue
REThinkWELL- the Use of Therapeutic Game to Reduce Mental Health Symptoms in Children and Adolescents
To test the effect of a game-based intervention in reducing clinical and subclinical symptoms of children and adolescents.
- Trial name
- NCT06529510
- Testing
- REThink therpeutic game
- Where
- Romania
- Volunteers
- 279 people, healthy volunteers welcome
- Sponsor
- Babes-Bolyai University
Sleep Disorder (Disorder), Autism Spectrum Disorder
"Sleep Patterns and EEG Structure in Youth With Autism: Links With Behavior and Parental Stress"
This retrospective observational study is designed to investigate sleep patterns, as well as both the macrostructure and microstructure of sleep, in a large cohort of children and adolescents diagnosed with Autism Spectrum…
- Trial name
- NCT07122388
- Testing
- Questionnaires about autism spectrum disorders and sleep and PSG., ADOS-2, ADI-R, SRS-2, PSG
- Where
- Italy
- Volunteers
- 187 people, healthy volunteers welcome
- Sponsor
- University of Campania Luigi Vanvitelli
Child Behavior Disorders, Child Mental Disorder
Epidemiology of Psychiatric Disorders in Children and Adolescent at Egypt
Pediatric, developmental and mental health problems are more common than renal, cardiac and renal problems. Compartmental problems were often conceptualised across two broad spectrums: internalising intrapersonal problems like…
- Conditions
- Child Behavior Disorders, Child Mental Disorder, Adolescent Behaviour Disorder
- Trial name
- NCT04762394
- Testing
- The Child Behavior Checklist (CBCL),
- Where
- Egypt
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Assiut University
Scoliosis Correction, Iron Deficiency
IntraVenous Iron in Kids With Iron Deficiency and Scoliosis Study
Adolescents and young adults undergoing spinal fusion surgery for the correction of scoliosis and other spinal deformity are at high risk of perioperative iron deficiency and anemia, yet the means and evidence for optimizing iron…
- Conditions
- Scoliosis Correction, Iron Deficiency, Transfusion Blood, Surgery Complications
- Trial name
- IV-KIDS (NCT07217873)
- Testing
- Ferric carboxymaltose IV
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Columbia University
Scoliosis; Adolescence, Anesthesia Recovery Period
IV Lidocaine Analgesia in Pediatric Scoliosis Surgery
Surgical correction of scoliosis in children is a long procedure, with an equivalently long recovery time, that is commonly performed at BC Children's Hospital.
- Trial name
- P-IVLT (NCT04069169)
- Testing
- Lidocaine, Saline Solution
- Where
- Canada
- Volunteers
- 48 people
- Sponsor
- University of British Columbia
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