Clinical trials: Children, Adolescents
Child, Preschool, Child
Monitoring Activity And Gait In Children
COHORT A: To study whether a digital health tool called Actigraph can be used to collect information on gait and physical activity in healthy children aged 3-17.
- Conditions
- Child, Preschool, Child, Adolescent
- Trial name
- MAGIC (NCT04823650)
- Testing
- COHORT A: Actigraph, Panoramic Bracelet and GENEActiv
- Where
- United States
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- Pfizer
Inflammatory Bowel Diseases, Functional Gastrointestinal Disorders
Functional Gastrointestinal Disorders in Pediatric IBD
Background: Persistent gastrointestinal symptoms have been described in patients who are considered in remission of their inflammatory bowel disease (IBD).
- Conditions
- Inflammatory Bowel Diseases, Functional Gastrointestinal Disorders, Pediatric Disorder, Anxiety Depression
- Trial name
- TFI-MICI (NCT03565263)
- Where
- France
- Volunteers
- 350 people
- Sponsor
- University Hospital, Caen
Smokeless Tobacco Cessation
Improvement in Knowledge and Perception About Hazards of Smokeless Tobacco
Oral cancer is a serious and growing problem in many parts of the globe. Oral cancer is the eighth most common cancer worldwide.The annual estimated incidence is around 275,000 for oral and 130,300 for pharyngeal cancers…
- Trial name
- NCT03418506
- Testing
- SMOKELESS TOBACCO AWARENESS PROGRAM
- Where
- Pakistan
- Volunteers
- 1,327 people
- Sponsor
- Aga Khan University
Physical Activity, Asthma
Physical Activity of Asthmatic Children
Physical activity is mandatory to the optimal development and health of children. The presence of asthmatic manifestations may influence the comportment of children and its family toward exercise and practice of sports.
- Conditions
- Physical Activity, Asthma, Child Development
- Trial name
- Asthmeact (NCT03232606)
- Where
- France
- Volunteers
- 90 people
- Sponsor
- Central Hospital, Nancy, France
Insomnia
Digital Cognitive Behavioral Treatment of Insomnia in Youth: An RCT Examining Feasibility, Acceptability, and Efficacy of NiteCAPP Jr
The proposed pilot will examine feasibility, acceptability, and preliminary efficacy of a digital CBT-I tailored for school-aged children.
- Trial name
- NiteCAPP JR (NCT07091149)
- Testing
- CBT-I
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of South Florida
Spina Bifida, Cerebral Palsy
Assessing Transition Practices for Children With Disabilities: Pathways to a Successful Adulthood
Transition to adult care is a purposeful and structured movement of youth with complex disabilities from child centered to adult oriented services. This complex and potentially challenging period requires careful planning.
- Conditions
- Spina Bifida, Cerebral Palsy, Spinal Cord Injury, Spastic Paraplegia
- Trial name
- NCT07706517
- Testing
- Chart review, Semi-structured interview
- Where
- France
- Volunteers
- 128 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Asthma
Evaluation of an Asthma Treatment Strategy Based on Exhaled Nitric Oxide Measurements in Adolescents
The purpose of ICAC-01 is to determine whether an asthma treatment strategy that measures exhaled nitric oxide (eNO) to indicate disease progression is more effective in treating asthma symptoms when combined with existing asthma…
- Trial name
- NCT00114413
- Testing
- Inhaled corticosteroids, eNO measurement
- Where
- 12 sites in United States
- Volunteers
- 547 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Obesity, Childhood, Obesity, Adolescent
Cognitive Function and Body Mass Index in Children and Adolescents
The child will complete computerized tasks and paper-pencil test, and will be presented with symbols, letters, or numbers on a computer screen and asked to respond by pressing a button on the computer.
- Conditions
- Obesity, Childhood, Obesity, Adolescent, Cognitive Orientation
- Trial name
- NCT03963557
- Where
- United Arab Emirates
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Imperial College London Diabetes Centre
Attention Deficit Disorder With Hyperactivity
A Noninterventional Genotype/Phenotype Study of mGluR Mutations in Children and Adolescents With ADHD
This noninterventional study will assess genomic changes in the metabotropic glutamate receptor (mGluR) network in children and adolescents with ADHD.
- Trial name
- NCT02811211
- Where
- United States
- Volunteers
- 1,894 people
- Sponsor
- Aevi Genomic Medicine, LLC, a Cerecor company
Diffuse Large Cell Lymphoma, Burkitt's Lymphoma
Treatment for Advanced B-Cell Lymphoma
To safely reduce the burden of therapy in children, adolescents and young adults with mature B-NHL by reducing the number of intrathecal (IT) injections by the introduction of IT Liposomal Cytarabine (L-ARA-C, [Depocyt®]) and…
- Conditions
- Diffuse Large Cell Lymphoma, Burkitt's Lymphoma, High Grade B-cell Lymphoma
- Trial name
- REBOOT (NCT01859819)
- Testing
- Rituximab, IT Cytarabine
- Where
- 5 sites in United States
- Volunteers
- 45 people
- Sponsor
- New York Medical College
Transcranial Direct Current Stimulation, Autistic Disorders Spectrum
A Machine Learning Approach for Predicting tDCS Treatment Outcomes of Adolescents With Autism Spectrum Disorders
Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by disturbances in communication, poor social skills, and aberrant behaviors.
- Conditions
- Transcranial Direct Current Stimulation, Autistic Disorders Spectrum, Electroencephalography, Machine Learning
- Trial name
- NCT05035511
- Testing
- tDCS
- Where
- Hong Kong
- Volunteers
- 90 people
- Sponsor
- The Hong Kong Polytechnic University
Adolescent Cancer Survivors, Childhood Cancer Survivors
IMpact of Mind-body Therapies (HYpnosis and Relaxation) on Anxiety in Children, Adolescents and Young Adults Who Had Been Treated in ONcology. Multicenter Study.
In France today, it is estimated that one in 850 people aged between 20 and 45 has been cured of cancer in childhood. Some descriptive studies have established that cancer diagnosis and treatment can affect psychological health…
- Conditions
- Adolescent Cancer Survivors, Childhood Cancer Survivors, Anxiety
- Trial name
- HARMONY-Impact (NCT07380672)
- Testing
- 10 mind-body therapy sessions (hypnosis or relaxation, depending on the patient's choice), 9 sessions of standard psychological care
- Where
- 5 sites in France
- Volunteers
- 558 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Monogenic Obesity
A Study Evaluating Mibavademab Treatment of Obesity Due to Leptin (LEP) Gene Mutations in Children, Adolescents and Adults
This study is researching an experimental drug called mibavademab. The study is focused on patients with a condition called monogenic obesity.
- Trial name
- NCT07220772
- Testing
- Mibavademab
- Where
- 3 sites in Germany, Turkey (Türkiye)
- Volunteers
- 4 people
- Sponsor
- Regeneron Pharmaceuticals
Autism Spectrum Disorder
Investigating Social Competence in Youth With Autism
Our treatment, SENSE Theatre, combines several well-documented, effective behavioral strategies and theatre techniques. The proposed project will extend previous findings showing improving improvement in memory for faces.
- Trial name
- NCT03368001
- Testing
- SENSE Theatre, Tackling Teenage Together
- Where
- 3 sites in United States
- Volunteers
- 318 people
- Sponsor
- Vanderbilt University Medical Center
Hypertension
Evaluation of the Safety, Efficacy and Pharmacokinetics of MICARDIS® (Telmisartan) in Children and Adolescents With Hypertension
Study to assess the blood pressure lowering effects of two doses of telmisartan over a four-week treatment period; to determine potentially effective doses for pediatric patients for future studies; to assess the safety and…
- Trial name
- NCT02242344
- Testing
- Telmisartan
- Volunteers
- 77 people
- Sponsor
- Boehringer Ingelheim
Hyperprolactinemia, Puberty Disorders
PROSA: Prolactin, Sex Hormones, Growth and Metabolic Biomarkers in Children and Adolescents on Antipsychotics
The objectives of this study are: 1. To determine the prevalence and degree of hyperprolactinemia in children and adolescents aged 7-18 years receiving antipsychotic medications 2.
- Conditions
- Hyperprolactinemia, Puberty Disorders, Metabolic Syndrome, Growth Disorders
- Trial name
- PROSA (NCT05033119)
- Where
- 3 sites in Denmark
- Volunteers
- 90 people
- Sponsor
- Ulla Schierup Nielsen
Respiratory Infection
A Randomized Trial of Vitamin D to Reduce Respiratory Infection
The goal of this study is to assess the effectiveness of vitamin D in reducing laboratory-confirmed influenza and in reducing non-influenza viral respiratory tract infections.
- Trial name
- NCT01705314
- Testing
- vitamin D supplements
- Where
- Vietnam
- Volunteers
- 1,300 people, healthy volunteers welcome
- Sponsor
- McMaster University
Quality of Life, Body Mass Index
Study of Parental Ratings of Quality of Life and Body Composition in 5-19 Year Olds While Participating in the Good NEWS 4 Kids Program
This study will compare changes in body composition (lean mass, fat, and bone)and parent ratings of quality of life in 5-19 Year Olds as a function of participation in one of four versions of the Good NEWS 4 Kids Program (GN4K).
- Trial name
- NCT01855009
- Testing
- MannaBears, AlgaeCal Calcium, Calcium carbonate
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Integrative Health Technologies, Inc.
Primary Headache, Migraine in Adolescence
nVNS for the Prevention and Treatment of Primary Headache
This study is a single-center, single-arm study. All subjects will receive the same treatment. Children and adolescents (7-20 years old) with migraine who met the inclusion criteria will be enrolled as subjects in the…
- Conditions
- Primary Headache, Migraine in Adolescence, Migraine in Children, Cluster Headache
- Trial name
- NCT06277063
- Testing
- Transcutaneous auricular vagus nerve stimulation
- Where
- China
- Volunteers
- 15 people
- Sponsor
- Nanfang Hospital, Southern Medical University
Diffuse Intrinsic Pontine Glioma
Biological Medicine for Diffuse Intrinsic Pontine Glioma (DIPG) Eradication
Diffuse Intrinsic Pontine Gliomas (DIPG) appear almost exclusively in children and adolescents, representing 15 to 20% of posterior fossa tumours.
- Trial name
- BIOMEDE (NCT02233049)
- Testing
- Erlotinib, Everolimus, Dasatinib
- Where
- France
- Volunteers
- 250 people
- Sponsor
- Gustave Roussy, Cancer Campus, Grand Paris
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