Clinical trials: Children, Adolescents
Generalized Anxiety Disorder, Separation Anxiety Disorder
Treatment of Pediatric Anxiety Disorders by Predicting Treatment Response Through Biocellular Markers and Sleep
1 out of 8 children, adolescents, and young adults suffer from an anxiety disorder. Studies over the past decade show that selective serotonin-reuptake inhibitors (SSRIs), a class of medication that treats anxiety in adults, also…
- Conditions
- Generalized Anxiety Disorder, Separation Anxiety Disorder, Social Phobia
- Trial name
- NCT02189213
- Testing
- Sertraline
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- New York State Psychiatric Institute
Autism Spectrum Disorder (ASD), Motivation
Motivation for Daily Living Skills
The goal of this clinical trial is to enhance motivation to complete daily living skills among 16 to 25-year-old autistic teens and young adults.
- Trial name
- NCT07159308
- Testing
- Intrinsic Motivation Treatment, Extrinsic Motivation Treatment, Combined Intrinsic and Extrinsic Motivation Treatment
- Where
- United States
- Volunteers
- 180 people
- Sponsor
- Children's Hospital of Philadelphia
Depression, Depressive Disorder
Manual-based Art Therapy for Adolescents With Depression
There is a need to evaluate different interventions in order to meet young people's needs of treatment. The study's goal is to find out if manual-based art therapy is a useful method for young people with depression and thus…
- Trial name
- NCT04603235
- Testing
- Manual-based Art Therapy
- Where
- Sweden
- Volunteers
- 10 people
- Sponsor
- Vastra Gotaland Region
Overweight and Obesity, Overweight Adolescents
Enhancing BodyWorks: A Canine Health Literacy Module
Dog ownership can serve as a vehicle for large-scale multi-level public health interventions, especially for pediatric overweight and obesity, due to dogs' unique place in children and adolescents' social networks.This study…
- Trial name
- BW (NCT04516252)
- Testing
- BodyWorks Intervention, Canine Curriculum, Ecological Momentary Assessment
- Where
- United States
- Volunteers
- 202 people
- Sponsor
- Children's Hospital Los Angeles
Hepatitis C Virus Infection
Study to Investigate Pharmacokinetics, Safety and Efficacy of Sofosbuvir/Velpatasvir/Voxilaprevir (SOF/VEL/VOX) Fixed Dose Combination (FDC) in Adolescents and Children With Chronic Hepatitis C Virus (HCV) Infection
The primary objective of this study is to evaluate the steady-state pharmacokinetics (PK) and confirm the age-appropriate dose of sofosbuvir/velpatasvir/voxilaprevir (SOF/VEL/VOX) fixed-dose combination (FDC) in pediatric…
- Trial name
- NCT03820258
- Testing
- SOF/VEL/VOX
- Where
- 10 sites in Italy, Poland and 1 more
- Volunteers
- 21 people
- Sponsor
- Gilead Sciences
Autoimmune Thyroiditis
Oxidative Status in Children With Autoimmune Thyroiditis
Oxidative status in autoimmune thyroiditis was not investigated previously in children and adolescents. We investigated oxidant and antioxidant systems in a cohort of Egyptian children and adolescents with AIT to explore their…
- Trial name
- NCT02318160
- Testing
- measurement of oxidant status in AIT
- Volunteers
- 64 people
- Sponsor
- Assiut University
Myopia Progressing
Light Diffraction Glasses in Preventing and Controlling Myopia in Adolescents
This study aims to evaluate the effectiveness of lenses with light diffraction glasses in controlling the progression of myopia in children and adolescents, and to explore the feasibility of effective design, and apply…
- Trial name
- NCT06927414
- Testing
- Functional lens
- Where
- China
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Shanghai Eye Disease Prevention and Treatment Center
Obesity, Obesity, Childhood
Community Based Obesity Prevention and Treatment Programme "6-10-14 for Health"
"6-10-14 for Health" is an integrated weight-loss intervention programme for obese children from Gdansk municipality. Both participants of the programme and their family members are offered a 12-month integrated intervention…
- Conditions
- Obesity, Obesity, Childhood, Health Program, Body Weight Changes
- Trial name
- NCT04143074
- Testing
- multidisciplinary behavioral intervention
- Where
- Poland
- Volunteers
- 6,000 people, healthy volunteers welcome
- Sponsor
- Michał Brzeziński
Overweight, Obesity
A Research Study on How Well Cagrilintide and CagriSema Work in Children and Adolescents With Excess Body Weight
This study will look at how well CagriSema and cagrilintide help children and adolescents with excess body weight lose weight. The study has 2 parts: main and extension study.
- Trial name
- NCT07253285
- Testing
- Cagrilintide, Semaglutide
- Where
- 121 sites in United States, Australia and 24 more
- Volunteers
- 460 people
- Sponsor
- Novo Nordisk A/S
Tic Disorders
Mobile App-assisted Behavioral Treatment in Children and Adolescents With Tics
Chronic tic disorders are neurodevelopmental disorders affecting 0.5-1% of children and adolescents. Tics present as sudden, rapid, repetitive non-rhythmic movements or vocalizations or a combination.
- Trial name
- NCT05390268
- Testing
- Mobile app-assisted behavioral treatment, Mobile app-assisted psychoeducation
- Where
- Denmark
- Volunteers
- 60 people
- Sponsor
- Aarhus University Hospital
Supportive Care, Childhood Cancer
Home Chemotherapy Intervention for Children With Cancer - a Feasibility Study
Children with cancer undergo intensive treatment with many serious side effects and frequent in- and outpatient visits. Studies show that the frequent hospitalizations are very disruptive to children and their families, who…
- Trial name
- INTACTatHome (NCT05372536)
- Testing
- parent-led home-administered low-dose Cytarabine
- Where
- Denmark
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Problem Behavior
Culturally Modified Family Based Therapy for Haitian Youth in South Florida
The CIFFTA study is a unique intervention that will develop and implement a culturally-specific, family-based individual, drug use, sexual risk and delinquency risk reduction program for Haitian youth ages 13-17 in Miami-Dade…
- Trial name
- NCT03876171
- Testing
- Haitian youth family-based intervention study: family functioning, Haitian youth intervention study: youth psychoeducational, Haitian family-based intervention study: psychoeducational
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- University of Miami
Overweight, Obesity
Electronic Health Technology for Assessment of Physical Activity and Eating Habits in Children and Adolescents Who Are Overweight and Those With Obesity
Aims: During the last decades overweight/obesity has increased markedly. They are associated with a high risk for diabetes and death. Effective intervention is mandatory.
- Trial name
- NCT01138293
- Testing
- motion detection with a motion sensor
- Where
- Germany
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- MEDIGREIF Inselklinik Heringsdorf
Attention Deficit Hyperactivity Disorder
Atomoxetine to Treat Korean Children and Adolescents With Attention-Deficit/Hyperactivity Disorder (ADHD)
The purpose of this study is to provide information regarding the relative effectiveness of three different atomoxetine doses in the treatment of Korean children and adolescents with Attention-Deficit/Hyperactivity Disorder (ADHD)
- Trial name
- NCT00568685
- Testing
- Atomoxetine Hydrochloride
- Where
- 3 sites in South Korea
- Volunteers
- 153 people
- Sponsor
- Eli Lilly and Company
Dravet Syndrome (DS), Lennox-Gastaut Syndrome (LGS)
A Study to Gather Information About Overall Occurrence and New Cases of Dravet and Lennox-Gastaut Syndromes in Children, Teenagers and Adults in Spain
The main aims of this study are to gather information about how many children, teenagers and adults in Spain have been diagnosed with Dravet syndrome and Lennox-Gastaut syndrome as well as to learn about the number of new Dravet…
- Trial name
- DRALEGA (NCT05982717)
- Testing
- No intervention
- Where
- 4 sites in Spain
- Volunteers
- 237 people
- Sponsor
- Takeda
Obesity
Effects of Mulberry Leaf Extract Formulation on Postprandial Glycemic Levels in Obese Children and Adolescents
The study entitled "Effects of mulberry leaf extract formulationon Postprandial Glycemic Peak in Obese Children and Adolescents: A Pilot Study" aims to evaluate the improvement in glycemic and insulinemic levels produced by a…
- Trial name
- PEDRED (NCT07494253)
- Testing
- Reducose
- Where
- Italy
- Volunteers
- 80 people
- Sponsor
- University of Bari Aldo Moro
Traumatic Brain Injury
Growth Hormone and Insulin Growth Factor 1 Deficiencies in Children/Adolescents Following Traumatic Brain Injury: The Impact on Growth and Neuropsychological Development
The purpose of this study is to look at the relationship between growth hormones, and recovery from a TBI - traumatic brain injury. It is believed that a TBI may interfere with the body's ability to produce growth hormones.
- Trial name
- NCT00929045
- Testing
- Growth Hormone Replacement
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Cardiometabolic Health, Gastro-intestinal Wellbeing
Effects of Wholegrains on Children's Health (KORN)
KORN investigates the effects of wholegrain oat and rye intake on health and cognitive wellbeing in children with overweight.
- Conditions
- Cardiometabolic Health, Gastro-intestinal Wellbeing, Cognitive Function, Overweight
- Trial name
- NCT04430465
- Testing
- Grain products high in wholegrains from oat and rye, Grain products low in wholegrains
- Where
- Denmark
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Asthma
Viapaed Study In Children And Adolescents With Asthma
Asthmatic children who remain symptomatic on inhaled corticosteroids (ICS) require an adjustment of their asthma therapy. Current guidelines suggest that the treatment options are either an increased dose of inhaled…
- Trial name
- NCT00315744
- Testing
- Salmeterol/fluticasone, Fluticasone propionate, Salbutamol
- Where
- 98 sites in Germany
- Volunteers
- 285 people
- Sponsor
- GlaxoSmithKline
Problem Behavior, Aggression
Mind-Body Skills Groups for Behavioral and Emotional Problems in War-Traumatized Male Adolescents in Gaza
The purpose of this study is to determine whether war-traumatize male adolescents with behavioral and emotional problems who participate in mind-body skills groups will have improvement in behavioral and emotional problems…
- Conditions
- Problem Behavior, Aggression, Posttraumatic Stress Disorder
- Trial name
- NCT02671487
- Testing
- Mind-Body Skills Groups
- Where
- Palestinian Territories
- Volunteers
- 115 people, healthy volunteers welcome
- Sponsor
- The Center for Mind-Body Medicine
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