Clinical trials: Children, completed
Cerebral Palsy, Traumatic Brain Injuries
Effects of an Adapted Ski/Snowboarding Program on Quality of Life in Children With Physical Disabilities
This study is assessing quality of life in children with a physical disability who participate in the Children's Hospital Colorado Hospital Sports Program (HSP), where children with physical disabilities are able to participate…
- Conditions
- Cerebral Palsy, Traumatic Brain Injuries, Spinal Cord Injuries, Physical Disability
- Trial name
- NCT02110290
- Where
- United States
- Volunteers
- 86 people
- Sponsor
- University of Colorado, Denver
Bipolar Spectrum Disorder
Open-Label Comparative Study of Risperidone Versus Olanzapine Versus Quetiapine for Mania in Children and Adolescents With Bipolar I and Bipolar II Disorder
The objective of this study is to compare the safety and effectiveness of Risperidone, Olanzapine, and Quetiapine in the treatment of mania in children and adolescents with Bipolar disorder over 8 weeks and then over an extension…
- Trial name
- NCT00182013
- Testing
- Risperidone, Olanzapine, Quetiapine
- Volunteers
- 106 people
- Sponsor
- Massachusetts General Hospital
Autism, Autistic Disorder
Use of Acupuncture In Children With Autistic Spectrum Disorder
This is a study of the efficacy of acupuncture in children with autism.
- Trial name
- NCT00352352
- Testing
- Tongue Acupuncture (Procedure)
- Where
- Hong Kong
- Volunteers
- 30 people
- Sponsor
- The University of Hong Kong
ADHD
KP415 Open-Label Safety Study in Children (6-12 Years of Age) With ADHD
This study is a multicenter, dose-optimized, open-label safety study with KP415 in children with Attention-Deficit/Hyperactivity Disorder (ADHD).
- Trial name
- NCT03460652
- Testing
- KP415 oral capsule
- Where
- 19 sites in United States
- Volunteers
- 282 people
- Sponsor
- Zevra Therapeutics
Cerebral Palsy
Correlation Between Clinical Measurement Scales for Gross Motor Function
Evaluating and applying an early and consistent rehabilitation approach to children with neurological impairments requires a multidisciplinary approach that involves different specialists, including pediatricians, pediatric…
- Trial name
- NCT06124352
- Testing
- Gross Motor Function Measurement - 66 (GMFM- 66), Bruininks- Oseretsky Motor Proficiency, the Peabody Developmental Motor Scale - Second Edition (PDMS-2
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Cairo University
BPG Intervention, Control
Neurodevelopmental Assessment of Children in Uganda and Malawi Using a Software Package
The investigators will use Brain Power Games as a neurocognitive "stress test" or medical "challenge" test, in order to evaluate or improve brain/behavior functional integrity in HIV-affected children.
- Trial name
- NCT03878147
- Testing
- Cognitive Games Training
- Where
- 2 sites in Malawi, Uganda
- Volunteers
- 599 people
- Sponsor
- Michigan State University
Dental Caries in Children, Knowledge, Attitudes, Practice
The Effect of Oral Health Education on Knowledge, Attitude, Practice and Dental Caries Among Egyptian School Children
Aim of the study Assessing the effect of an oral health education program on knowledge, attitude, practice, and dental caries among a group of school children in a governmental school in Fayoum, Egypt.
- Trial name
- KAP (NCT06280547)
- Testing
- Oral health education
- Where
- Egypt
- Volunteers
- 115 people, healthy volunteers welcome
- Sponsor
- Cairo University
Appendicitis, Children
Randomized Controlled Trial of a Patient Activation Tool in Pediatric Appendicitis (Antibiotics Alone vs. Appendectomy)
The purpose of this study is to determine if a patient activation tool (PAT) can improve decision making and patient centered outcomes in pediatric patients with appendicitis and their caregivers choosing between antibiotics…
- Trial name
- Appy-PAT (NCT02110485)
- Testing
- Patient Activation Tool
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Peter Minneci
SARS-CoV-2 Infection, COVID-19
Study to Evaluate the Safety, Tolerability, and Immunogenicity of an RNA Vaccine Candidate Against COVID-19 in Healthy Children
This is a Phase 1/2/3 study in healthy children. Dependent upon safety and/or immunogenicity data generated during the course of this study, and the resulting assessment of benefit-risk, the safety, tolerability, and…
- Trial name
- NCT04816643
- Testing
- Biological/Vaccine: BNT162b2 10mcg, BNT162b2 20mcg, BNT162b2 30mcg
- Where
- 128 sites in United States, Brazil and 4 more
- Volunteers
- 11,837 people, healthy volunteers welcome
- Sponsor
- BioNTech SE
Celiac Disease in Children, Pediatric Disorder
Serological Identification of Celiac Disease in Kids
The investigators aim to examine the feasibility of incorporating serological celiac disease (CD) screening into general pediatric outpatient clinics in Sweden and through structured monitoring examine the effects of diagnosing…
- Conditions
- Celiac Disease in Children, Pediatric Disorder, Health, Subjective, Growth Delay
- Trial name
- SICK (NCT03966625)
- Testing
- tissue transglutaminase autoantibodies
- Where
- 2 sites in Sweden
- Volunteers
- 496 people, healthy volunteers welcome
- Sponsor
- Sahlgrenska University Hospital
Hypotension
Dose-response Study of Sodium Nitroprusside in Children Requiring Controlled Hypotension in the Operating Room
Sodium nitroprusside (SNP) has been approved for control of blood pressure in adults, yet there are no controlled studies in children.
- Trial name
- NCT00135668
- Testing
- Nitroprusside
- Where
- United States
- Volunteers
- 211 people
- Sponsor
- The Emmes Company, LLC
Schizophrenia, Schizoaffective Disorder
Second-Generation Antipsychotic Treatment Indication Effectiveness And Tolerability In Youth (Satiety) Study
The purpose of this study is to get a better understanding of the side effect burden and identify predictors of psychotic, mood and aggressive disorders in children and adolescents.
- Conditions
- Schizophrenia, Schizoaffective Disorder, Schizophreniform Disorder, Psychotic Disorder, Not Otherwise Specified
- Trial name
- SATIETY (NCT01269710)
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- University of North Carolina, Chapel Hill
Disruptive Mood Dysregulation Disorder
Adapting DBT for Children With DMDD: Pilot RCT
This study examines feasibility and preliminary efficacy of Dialectical Behavior Therapy adapted to children (DBT-C). DBT-C as compared to treatment-as-usual (TAU) is hypothesized to have lower drop-out rate, and higher treatment…
- Trial name
- NCT01862549
- Testing
- Dialectical Behavior Therapy for children, Treatment as Usual
- Where
- United States
- Volunteers
- 43 people
- Sponsor
- Weill Medical College of Cornell University
Neurofibromatosis 1 and 2 (NF1 and NF2)
A Single Center Pilot Study to Assess the Intra-observer Reliability of Measuring Muscle Strength Using a Hand Held Dynamometer in Children and Adults With Neurofibromatosis Type 1 (NF1) and Type 2 (NF2)
Patients with clinically confirmed neurofibromatosis type 1 (NF1) or neurofibromatosis type 2 (NF2) or a known neurofibromatosis (NF) mutation aged 5 years and above will be eligible to participate and will be recruited from the…
- Trial name
- NCT03672838
- Testing
- hand-held dynamometer
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- NYU Langone Health
Physical Activity
An Intervention Study to Assess the Role of the Built Environment on Physical Activity and Active Transportation to School in Children and Youth
The purpose of this study is to evaluate if changes to the built environment influence physical activity and active transport to school in children and youth.
- Trial name
- ASAP-Jr (NCT01711138)
- Where
- Canada
- Volunteers
- 573 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Pain Management, Nonpharmalogical Pain Management
Impact of Buzzy and Finger Puppets on Children's Pain, Fear, and Anxiety During Venipuncture
This study evaluates the impact of the Buzzy device and finger puppet distraction on pain, fear, and anxiety in children aged 4-7 undergoing venipuncture in a pediatric emergency department.
- Conditions
- Pain Management, Nonpharmalogical Pain Management, Children Pain Management
- Trial name
- Pain Relief (NCT06849648)
- Testing
- The Buzzy Device, Finger Puppet
- Where
- Turkey (Türkiye)
- Volunteers
- 102 people
- Sponsor
- Kutahya Health Sciences University
MNRI, Development Delay
Effects of MNRI Therapy on Fine Motor Skills in Children With Developmental Delays.
Developmental delay refers to a child's failure to achieve age-appropriate developmental milestones and may affect multiple developmental domains.
- Trial name
- NCT07764926
- Testing
- MNRI, Conventional Physiotherapy without MNRI
- Where
- Pakistan
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Self Care
Evaluation of the Eversense Continuous Glucose Monitoring System in Type I Diabetic Youth
The purpose of this clinical investigation is to provide pilot clinical data to direct pivotal study development for the pediatric indication of the Senseonics Continuous Glucose Monitoring System (CGM) measurements when compared…
- Trial name
- FNH (NCT03815552)
- Testing
- Eversense Continuous Glucose Monitoring
- Where
- Germany
- Volunteers
- 15 people
- Sponsor
- Kinderkrankenhaus auf der Bult
Obesity
Virtual Sprouts: Web-based Gardening Games to Teach Nutrition and Combat Obesity
The purpose of this study is to develop, disseminate, and evaluate a web-based nutrition and gardening game using interactive, multiplatform and mobile gaming, rich narrative, a pedagogical agent, meaningful play, and…
- Trial name
- NCT02017158
- Testing
- Virtual Sprouts
- Where
- 2 sites in United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Autism
Open Label of Clinical Trial of Sulforaphane in Children With Autism
This is an open-label, 4-month study examining the effects of Sulforaphane (SF) on behavior in children with ASD and the correlation between behavior change and urinary metabolites.
- Trial name
- NCT02654743
- Testing
- Sulforaphane
- Volunteers
- 21 people
- Sponsor
- University of California, San Francisco