Clinical trials: Children Development
Growth Hormone Disorder, Adult Growth Hormone Deficiency
First Human Dose Trial of NNC0195-0092 (Somapacitan) in Healthy Subjects
This trial is conducted in Europe. The aim of this trial is to assess safety, tolerability, pharmacokinetics (the exposure of the trial drug in the body) and pharmacodynamics (the effect of the investigated drug on the body) of…
- Conditions
- Growth Hormone Disorder, Adult Growth Hormone Deficiency, Growth Hormone Deficiency in Children, Healthy
- Trial name
- NCT01514500
- Testing
- somapacitan
- Where
- Germany
- Volunteers
- 105 people
- Sponsor
- Novo Nordisk A/S
Down Syndrome, Child Obesity
HomeGrown: A Family-based Lifestyle Intervention to Support Healthy Development of Young Children With Down Syndrome
The goal of this project is to evaluate an adapted health promotion program, HomeGrown, designed to improve the health of young children with Down syndrome by supporting families in making healthy home environmental changes.
- Trial name
- HomeGrown (NCT07296861)
- Testing
- The HomeGrown, Waitlist
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- UNC Lineberger Comprehensive Cancer Center
Intellectual Disabilities (F70-F79), Autism
Optimizing Dimensions of Reinforcement
This study is designed to better understand how certain features of reinforcement affect learning and motivation in individuals with intellectual and developmental disabilities (IDD).
- Trial name
- NCT07137273
- Testing
- Operant Conditioning Tasks with Reinforcement Manipulations
- Where
- 3 sites in United States
- Volunteers
- 30 people
- Sponsor
- Auburn University
Acute Lymphoblastic Leukemia, Leukemia, Acute Myeloid (AML), Child
Safety Study of Gene Modified Donor T-cells Following TCRαβ+ Depleted Stem Cell Transplant
This study will evaluate pediatric patients with malignant or non-malignant blood cell disorders who are having a blood stem cell transplant depleted of T cell receptor (TCR) alfa and beta cells that comes from a partially…
- Conditions
- Acute Lymphoblastic Leukemia, Leukemia, Acute Myeloid (AML), Child, Lymphoma, Non-Hodgkin, Myelodysplastic Syndrome
- Trial name
- NCT02065869
- Testing
- BPX-501 T cells, Rimiducid
- Where
- 4 sites in Italy, United Kingdom
- Volunteers
- 187 people
- Sponsor
- Bellicum Pharmaceuticals
Molar Incisor Hypomineralization
Restoration of Permanent Molars Affected With (MIH) Using Composite Restorations or Preformed Metal Crowns
The aim of this study is to compare clinical outcome of using direct esthetic composite restorations in managing MIH cases and the use of preformed metal crowns.
- Trial name
- NCT04658602
- Testing
- Preformed stainless steal crown cemented by glass ionomer lutting cement (Ketac cem,3M Espe)
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Nada Mahmoud Abd El-Azim Mohamed
Autism Spectrum Disorder, Wandering Behavior
A Pilot Study to Characterize the Household Impact of Locating Devices for Children With ASD Who Wander
This pilot study will obtain preliminary data about the impact of wearable electronic tracking devices (ETDs) as an intervention for children with autism spectrum disorders (ASD) who wander.
- Trial name
- CHILD (NCT03814902)
- Testing
- Electronic Tracking Device
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- Northwell Health
Congenital Hypothyroidism, Metabolic Syndrome
Metabolic Risk Assessment in Prepubertal Children With Congenital Hypothyroidism
We propose a multicenter prospective study to define the prevalence and severity score of metabolic syndrome in a prepubertal pediatric cohort with congenital hypothyroidism, compared to a healthy and normal-weight pediatric…
- Trial name
- IpoMet (NCT07126353)
- Testing
- prospective observational study (clinical, hormonal and auxological data)
- Where
- Italy
- Volunteers
- 170 people, healthy volunteers welcome
- Sponsor
- Buzzi Children's Hospital
Autism Spectrum Disorder, Developmental Delay
Can Novel Telemedicine Tools Reduce Disparities Related to Early Identification of Autism
In this study, the investigators are trying to find new ways to screen for autism spectrum disorder (ASD) in young children. The investigators want to see if people like pediatricians can screen children for ASD while a…
- Trial name
- NCT03847337
- Testing
- Telehealth-Screening Tool for Autism in Toddlers (STAT), Telehealth-Autism Spectrum Disorder-Pediatrics (ASD-PEDS)
- Where
- United States
- Volunteers
- 144 people
- Sponsor
- Vanderbilt University Medical Center
Attention-Deficit/Hyperactivity Disorder (ADHD), Autism Spectrum Disorder
Home Play-based Intervention for Parents and Infants
The goal of this clinical trial is to learn whether a 12-week home-based intervention (Sociometric Play-based Remediation of Individual Neurodevelopmental Trajectories (SPRINT)) helps support parenting and the development of…
- Conditions
- Attention-Deficit/Hyperactivity Disorder (ADHD), Autism Spectrum Disorder, Premature Birth, Global Developmental Delay
- Trial name
- SPRINT (NCT07716072)
- Testing
- SPRINT Intervention, Waitlist Protocol
- Where
- Singapore
- Volunteers
- 120 people
- Sponsor
- Nanyang Technological University
NVP Plasma Level, NVP Related Mutation
Nevirapine Clearance After Short-term Highly Active Antiretroviral Therapy (HAART) for Prevention of Mother to Child Transmission of HIV (PMTCT)
Three-drug combination of antiretroviral regimens has been used increasingly in HIV-infected pregnant women worldwide, both for the prevention of mother to child transmission of HIV (PMTCT) and for women's own health.
- Conditions
- NVP Plasma Level, NVP Related Mutation, 3TC Related Mutation
- Trial name
- NCT00872872
- Testing
- AZT/3TC 2 weeks after delivery
- Where
- Thailand
- Volunteers
- 30 people
- Sponsor
- Thai Red Cross AIDS Research Centre
Weaning
Complementary Weaning With Adult Food Typical of the Mediterranean Diet
A Randomized Controlled Clinical Trials was conducted to study the medium-long term impact of a complementary weaning using adult foods typical of Mediterranean Diets (MD) on children taste development and eating habits, and on…
- Trial name
- NCT05297357
- Testing
- Mediterranean Diet weaning scheme
- Volunteers
- 394 people, healthy volunteers welcome
- Sponsor
- Federico II University
Prematurity, Speech Sound Disorder
Early Intervention in Very Preterm Children
The aim of the present study is to examine the effectiveness of a short, highly structured parent based speech intervention program on speech development in very preterm children with a Speech Sound Disorder (SSD) at 2 years of…
- Trial name
- NCT01352481
- Testing
- Early parent-based speech intervention program
- Where
- Netherlands
- Volunteers
- 25 people
- Sponsor
- Erasmus Medical Center
Autism, Autism Spectrum Disorder
Promoting Emotional and Autonomic Control Through Guided Breathing Exercises for Emerging Adults With Autism
This study examines the impact of guided breathing exercises on stress and heart rate variability (HRV) in autistic young adults.
- Trial name
- PEACE-A (NCT07238153)
- Testing
- Guided breathing exercise - SPB, Guided breathing exercise - HRV-BF
- Where
- 2 sites in Belgium
- Volunteers
- 68 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Autism Spectrum Disorder
Ball Exercises and Stereotypic Behavior in Autism Spectrum Disorder
Autism spectrum disorder (ASD) is a neuro-behavioral disorder associated with repetitive movements. The role of physical therapist towards an autistic child is most neglected one.
- Trial name
- NCT05045339
- Testing
- Ball Exercises
- Where
- Pakistan
- Volunteers
- 30 people
- Sponsor
- University of Faisalabad
Autism Spectrum Disorder
Sulforaphane Treatment of Children With Autism Spectrum Disorder (ASD)
ASD is a diverse disorder starting in early childhood and characterized by social communication impairment as well as restricted interests and repetitive behaviors.
- Trial name
- NCT02561481
- Testing
- Sulforaphane
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Massachusetts, Worcester
Delayed;Development;Physical, Delayed; Development, Intellectual
Etiology of Motor Developmental Delay in Children
This study aims to identify the etiology of children with motor developmental delay, in association with the results of magnetic resonance imaging and genetic analysis.
- Trial name
- MDD (NCT03130972)
- Volunteers
- 1,355 people
- Sponsor
- Bundang CHA Hospital
Autism Spectrum Disorder, Obesity, Childhood
A YouTube Curriculum for Children With Autism and Obesity
Parents as primary caregivers play an important role in shaping children's mealtime and eating behaviors; and in preventing weight gain.
- Trial name
- NCT06259539
- Testing
- YouTube nutrition education
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Texas Woman's University
Autism Spectrum Disorder, Visual Function
Characteristics of Eye Diseases in Children and Adolescents With Autism Spectrum Disorders and the Effect of Corresponding Treatment on the Quality of Life of Children and Adolescents With Autism and Their Caregivers
This study mainly investigated the incidence of eye diseases in children with autism spectrum disorder(ASD) in Tianjin area, and analyzed related risk factors, so as to raise attention to eye diseases in children with ASD.
- Trial name
- NCT06122519
- Where
- China
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Tianjin Eye Hospital
Developmental Disabilities
The Experiences of Parents Learning Physiotherapy Techniques for Their Child
The experiences of learning from paediatric physiotherapists were explored through unstructured interviews applying Colazzi's method to interpret the data.
- Trial name
- NCT02090946
- Where
- United Kingdom
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Western Sussex Hospitals NHS Trust
Autism Spectrum Disorder
A Trial of Project ImPACT in Early Intervention
Our pilot study will address a number of pressing questions, including: Can community clinicians successfully coach parents of children with ASD in evidence-based practice to achieve positive outcomes for their children and…
- Trial name
- NCT04729127
- Testing
- Project ImPACT
- Where
- United States
- Volunteers
- 79 people
- Sponsor
- University of Pennsylvania