Clinical trials: Children With Autism
Autism Spectrum Disorder
Efficacy of Bumetanide in Children With Autism Spectrum Disorder Guided by Peripheral Blood Biomarkers and Machine Learning Models
The objective of this study is to learn if bumetanide could alleviate the clinical symptoms in children with autism spectrum disorder (ASD), who has been predicted as high responders to bumetanide via a cytokine-based predictive…
- Trial name
- NCT07005414
- Testing
- Bumetanide, Treatment as usual (TAU)
- Where
- China
- Volunteers
- 66 people
- Sponsor
- Fei Li
Autism
Improving Working Memory of Children With Autism
Existing findings suggest that challenges in working memory (WM) of children with autism are common (Habib, Pollick, Melville, \& 2019).
- Trial name
- NCT04209452
- Testing
- Rehearsal strategy, Reinforcement, Rehearsal strategy and reinforcement
- Where
- 3 sites in China
- Volunteers
- 15 people
- Sponsor
- Arizona State University
Autism Spectrum Disorder
Evaluation of Behavioural Psycho & Physiological Responses in People With ASD During a Blood Test in Routine Care Practice
The project is a prospective study designed to characterize behaviour and its psycho-physiological correlates of participants with ASD (children and adults) in comparison with subjects without ASD matched in age during blood test…
- Trial name
- AUTICOPP (NCT04638452)
- Testing
- Video & movements recording, Questionnaires
- Where
- France
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Charles Perrens, Bordeaux
Autism Spectrum Disorder, Caregiver Burden
Caregivers of Children With Autism Spectrum Disorder
This study aims to examine the relationship between caregiving burden and physical activity, exercise self-efficacy, and perceived exercise benefits and barriers in caregivers of Caregivers of children with autism spectrum…
- Conditions
- Autism Spectrum Disorder, Caregiver Burden, Exercise, Physical Activity
- Trial name
- NCT06518109
- Testing
- Zarit Caregiver Burden Scale
- Where
- Turkey (Türkiye)
- Volunteers
- 55 people
- Sponsor
- Gulhane School of Medicine
Autism Spectrum Disorder
Impact of Early Interventions on Neurocognitive Profile of Children With Autism Spectrum Disorder
The Early start Denver model (Rogers, 2010; Dawson, 2010) is a developmental and behavioral model that aim to enhance socio-comunicative abilities and also global development of children with Autism spectrum disorder (ASD).
- Trial name
- IDEAEYE (NCT03254264)
- Testing
- Early Start Denver Model, 'as-usual' intervention
- Where
- France
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Hôpital le Vinatier
Autism, Intellectual Disabilities With Other Behavioral Symptoms
Regulating Together for Intellectual Disability and Autism: A Group Behavioral Therapy for for Emotion Dysregulation
The goal of this study is to help children with autism and a co-occurring intellectual disability and their families learn practical strategies for managing issues like irritability, aggression, and other challenging behaviors.
- Conditions
- Autism, Intellectual Disabilities With Other Behavioral Symptoms, Intellectual Disability
- Trial name
- RT-ID (NCT07624448)
- Testing
- Regulating Together group therapy
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Children's Mercy Hospital Kansas City
Autism Spectrum Disorders
A Comparative Study of Driving Performance Among Adolescents With Autism Spectrum Disorder and Neurotypical Adolescents
The primary objective of this study is to compare the number of driving errors made by novice adolescents (0-5 hours of driving instruction) with ASD to those made by neurotypical adolescents during a standardized driving…
- Trial name
- Perf-TSA (NCT07630298)
- Testing
- Assessment of executive functions and attention, Evaluation on a driving simulator, Evaluation on-road
- Where
- France
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Hopital La Musse
Autism
Safety and Efficacy of Stem Cell Therapy in Patients With Autism
Autism is one of those disorders in Autism spectrum disorders (ASD), which characterized by social interaction abnormalities, impaired verbal and non-verbal communication, and repetitive, obsessive behavior, while the therapeutic…
- Trial name
- NCT01343511
- Testing
- human cord blood mononuclear cells, human cord blood mononuclear cells and human umbilical cord mesenchymal stem cells
- Where
- China
- Volunteers
- 37 people
- Sponsor
- Shenzhen Beike Bio-Technology Co., Ltd.
Autism Spectrum Disorder
Home-based Augmented Reality Storybook Training Modules for Children With Autism Spectrum Disorder
Autism spectrum disorder (ASD) is a lifelong neurodevelopmental disability with increasing prevalence worldwide. The main difficulties include poor social interaction and self-regulation skills.
- Trial name
- NCT05666934
- Testing
- Augmented Reality Storybook
- Where
- Taiwan
- Volunteers
- 15 people
- Sponsor
- National Cheng Kung University
Autism Spectrum Disorder
Effectiveness of the Care Coordination, Assessment, and Responsive Engagement Program for Transition-aged Adolescents (t-CARE) With ASD
An analysis of data for adolescents and young adults diagnosed with Autism Spectrum Disorders (ASDs) who are evaluated as part of the Care Coordination, Assessment, and Responsive Engagement for transition-aged adolescents…
- Trial name
- t-CARE (NCT03019952)
- Testing
- Care Coordination Visit
- Where
- United States
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Milton S. Hershey Medical Center
Anxiety Disorders in Youth With Autism, Asperger's Syndrome, and Pervasive Developmental Disorder Not Otherwise Specified
Cognitive Behavioral Therapy (CBT) for Anxiety Disorders in Autism: Adapting Treatment for Adolescents
Comorbid anxiety disorders affect as many as 80% of youth with autism spectrum disorders, causing substantial distress and impairment over and above the autism spectrum diagnosis alone.
- Trial name
- NCT01177969
- Testing
- Cognitive-Behavioral Therapy, Wait-list
- Where
- 2 sites in United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- University of South Florida
Autism Spectrum Disorder
The Westmead Feelings Program Intervention for Chinese Children With Autism Spectrum Disorder in Hong Kong
The goal of this intervention is to evaluate the effectiveness of delivering the Westmead Feelings Program 2 to children with Autism Spectrum Disorder in primary schools in Hong Kong.
- Trial name
- NCT06206070
- Testing
- The Hong Kong version of Westmead Feeling Program 2
- Where
- Hong Kong
- Volunteers
- 85 people
- Sponsor
- The University of Hong Kong
Mental Health Issue, Anxiety Disorders
Arts-based Social Prescribing for Mental Health
This is a parallel-group randomised-controlled trial aiming to assess the effect of exposure to the arts on mental health and wellbeing of community dwelling recipients of mental health care.
- Conditions
- Mental Health Issue, Anxiety Disorders, Affective Disorders, Affective Disorders, Psychotic
- Trial name
- AoP-II (NCT07137572)
- Testing
- Art Prescription
- Where
- Greece
- Volunteers
- 541 people
- Sponsor
- KAVADIA ELENI
Autism Spectrum Disorder
Tracking Intervention Effects With Eye Tracking
This pilot study examines concurrent and predictive relationships between eye tracking and clinical outcomes during a 16-week behavioral intervention (PRT) for children with ASD.
- Trial name
- NCT02856061
- Testing
- Pivotal Response Treatment
- Where
- United States
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Yale University
Specific Learning Disorder, Intellectual Disability, Mild to Moderate
SWELE Program: An Unstructured Outdoor Play With Mindfulness-based Interventions to Promote Mental Health Among Students With Special Education Needs
This is an observational study with the aim of SWELE Programme is to raise mental health knowledge and awareness by implementing a play-based approach on Supporting Wellness in E-Child Learning Environments (SWELE) programme…
- Conditions
- Specific Learning Disorder, Intellectual Disability, Mild to Moderate, Autism Spectrum Disorder, Attention Deficit Hyperactivity Disorder
- Trial name
- SEN (NCT06112483)
- Testing
- SWELE Programme
- Volunteers
- 1,064 people
- Sponsor
- Chinese University of Hong Kong
Autistic Disorders Spectrum
The Efficacy of Robot-enhanced Therapy for Children With Autism Spectrum Disorders
This trial will test the efficacy of robot-enhanced interventions for developing social skills in children with Autism Spectrum Disorders (ASD).
- Trial name
- DREAM-RCT (NCT03323931)
- Testing
- (2) robot--enhanced intervention, (1) discrete trial training / cognitive-behavior therapy
- Where
- Romania
- Volunteers
- 70 people
- Sponsor
- Babes-Bolyai University
Autistic Disorder
A Study of N-Acetyl Cysteine in Children With Autism
The purpose of the study is to test the tolerability and efficacy of N-Acetyl Cysteine (NAC) in children with Autism. NAC is a compound that increases the levels of Glutathione, the body's main antioxidant.
- Trial name
- NCT00627705
- Testing
- N-Acetyl Cysteine
- Where
- United States
- Volunteers
- 43 people
- Sponsor
- Stanford University
Autism Spectrum Disorder, Autism in Children
Abdominal Transcutaneous Electrical Acupoint Stimulation on Children With Autism Spectrum Disorder
The goal of this clinical trial is to learn if abdominal transcutaneous electrical acupoint stimulation (abdominal TEAS) works to treat autism spectrum disorder (ASD) in children.
- Trial name
- TEAS/ASD (NCT06763237)
- Testing
- abdominal transcutaneous electrical acupoint stimulation (abdominal TEAS)
- Where
- 2 sites in China
- Volunteers
- 42 people
- Sponsor
- First Affiliated Hospital Xi'an Jiaotong University
Autism Spectrum Disorder, Self-Injurious Behavior
Deep Brain Stimulation in Children With Autism
The purpose of this study is to evaluate the safety and possible effectiveness of deep brain stimulation (DBS) of the nucleus accumbens in children with autism spectrum disorder and treatment-refractory, repetitive self-injurious…
- Trial name
- NCT03982888
- Testing
- Deep Brain Stimulation, DBS
- Where
- Canada
- Volunteers
- 6 people
- Sponsor
- The Hospital for Sick Children
Autism Spectrum Disorder
Occupational Therapy Intervention in Children Diagnosed With Early and Late Autism Spectrum Disorder
Occupational Therapy Intervention in Children Diagnosed with Early and Late Autism Spectrum Disorder
- Trial name
- NCT07740863
- Testing
- Occupational Therapy Intervention
- Volunteers
- 30 people
- Sponsor
- SEDANUR GÜRLEK
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