Clinical trials: Children With Autism
Autism Spectrum Disorder, Autism
In-Person Mindfulness-based Intervention for Adolescents With Autism Spectrum Disorder and Their Caregivers
Adolescents with ASD often have co-occurring mental health symptoms like stress, anxiety, and depression. The investigators are conducting this research study to develop interventions for adolescents with ASD that will improve…
- Trial name
- NCT06577623
- Testing
- MINDful TIME
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- Southwest Autism Research & Resource Center
Visual Rehabilitation, Visual Impairment, Autism Spectrum Disorder, Developmental Disabilities, Intellectual Disability, Behavioral Symptoms
Evaluation of a Program to Enhance Ophthalmic Compliance in Children and Adolescents With Special Needs
The goal of this clinical trial is to learn about the effects of the structured program incorporating contextual, behavioral, and cognitive strategies to improve compliance of children and adolescents with special needs during…
- Trial name
- NCT06717282
- Testing
- visual rehabilitation for ophthalmic compliance, Using contextual, behavioral, and cognitive-based stragegies to develop training programs
- Where
- Taiwan
- Volunteers
- 20 people
- Sponsor
- National Taiwan University Hospital
Obsessive-Compulsive Disorder, Autism Spectrum Disorder
ICBT for OCD in Children With Autism
The purpose of this trial is to evaluate the clinical efficacy, the cost-effectiveness and the effect durability of a therapist-guided, internet-delivered cognitive-behavior therapy intervention for obsessive-compulsive disorder…
- Trial name
- NCT06582225
- Testing
- Internet-delivered exposure and response prevention (I-ERP), Internet-delivered stress management (I-SM)
- Where
- 3 sites in Sweden
- Volunteers
- 220 people
- Sponsor
- Karolinska Institutet
Autism Spectrum Disorder, Executive Dysfunction
Transcranial Direct Current Stimulation in Children With Autism
Although many children diagnosed with autism spectrum disorder (ASD) make significant progress in learning and their cognitive skills improve with applied behavior analysis (ABA), there are a significant number of children who…
- Trial name
- tDCS (NCT07092280)
- Testing
- Active tDCS
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- New York State Institute for Basic Research
Autism, Autism Spectrum Disorder
Neural and Behavioral Outcomes of Social Skills Groups in Children With Autism Spectrum Disorder (ASD)
The purpose of this study is to compare two different treatment approaches to social skills groups for high-functioning children with Autism Spectrum Disorder (ASD).
- Trial name
- NCT01190917
- Testing
- Cognitive Behavioral Therapy (CBT), Play Therapy
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Autism Spectrum Disorder
Parent Training to Enhance Social Success for Children With Autism Spectrum Disorder
Children with autism spectrum disorder (ASD) exhibit characteristic deficits in social initiation and there are no empirically validated treatments specifically for this core deficit.
- Trial name
- NCT03177525
- Testing
- Social SUCCESS, Wait List
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Stanford University
Autism
Fluoxetine Essay in Children With Autism
This study is a comparative, double blind, placebo controlled trial of 6-months duration designed to evaluate 1) the effects of fluoxetine in 5 to 12 years old autistic children, 2) the effects of fluoxetine on serotoninergic…
- Trial name
- FAIR (NCT00873834)
- Testing
- fluoxetine
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Autism Spectrum Disorder, Movement Disorders
Database Of Clinical Data For Individuals With Variants In The IRF2BPL Gene
This protocol serves as a data collection tool for individuals with variants (missense, nonsense, frameshifts) in the IRF2BPL gene (MIM 611720), which causes Neurodevelopmental Regression, Seizures, Autism and Developmental Delay…
- Conditions
- Autism Spectrum Disorder, Movement Disorders, Seizures, Dystonia
- Trial name
- IRF2BPL (NCT03892798)
- Testing
- No interventions are planned
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Dystrophinopathies
Decoding Central Defects in Dystrophinopathies From Diagnostic to Remediation
The study aims to identify a genotype/phenotype correlation by analyzing more finely the neurodevelopmental disorders in DMD patients.
- Trial name
- DECODYS (NCT07125898)
- Where
- France
- Volunteers
- 110 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Autism
Long-Term Olanzapine Treatment in Children With Autism
This study will determine the short- and long-term safety and effectiveness of the drug olanzapine (Zyprexa®) for reducing symptoms of autism in children.
- Trial name
- NCT00183404
- Testing
- Olanzapine
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Drexel University
Autism Spectrum Disorder
Enhancing Social Competence in Adults With Autism
SENSE Theatre®, combines several well-documented, effective behavioral strategies, such as the inclusion of trained peer models, theatre play techniques involving predictable (i.e., scripted) and flexible (improvised) role-play…
- Trial name
- NCT04349644
- Testing
- SENSE Theatre
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- Vanderbilt University Medical Center
Autism Spectrum Disorder
Effectiveness of a 6-week Hippotherapy Program in Children With Autism Spectrum Disorder
The prevalence of autism spectrum disorders (ASD) has increased dramatically in the last decade. The increasing occurrence of ASD creates an imperative need to test the effectiveness and efficacy mechanisms of appropriate…
- Trial name
- NCT04772898
- Testing
- Hippotherapy
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Creighton University
ADHD, Asperger Syndrome
A Prospective Observational Study of Family-based Interventions for Children With Neuropsychiatric and/or Psychiatric Disorders
The purpose of this study is to examine the feasibility and the effects of family-based interventions for children (aged 5-12) with neuropsychiatric and psychiatric disorders in Finnish health care settings.
- Conditions
- ADHD, Asperger Syndrome, Child Behavior Disorders
- Trial name
- NCT02250339
- Testing
- LAKU family program, Etä-LAKU family program, Family therapy
- Where
- Finland
- Volunteers
- 230 people
- Sponsor
- Social Insurance Institution, Finland
Autistic Disorder
A Study of Pregnenolone in the Treatment of Individuals With Autism
This study will assess the tolerability and effectiveness of pregnenolone in the treatment of behavioral deficits in adults with autism.
- Trial name
- NCT01881737
- Testing
- Pregnenolone
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Stanford University
Developmental Disability, Development Delay
Early Detection of Children With Developmental Disabilities in Assiut Governorate
The study aimed to determine the effectiveness of a designed training program for nurses toward early detection of developmental disabilities among children (0-3 years).
- Conditions
- Developmental Disability, Development Delay, Motor Delay, Down Syndrome
- Trial name
- NCT06263777
- Testing
- Nurses training program on early detection of disability
- Where
- Egypt
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Beni-Suef University
Autism Spectrum Disorder, Transition
Evaluating the Efficacy and Effectiveness of SCOPE - RCT
The study will entail an evaluation of the feasibility, acceptability, efficacy and effectiveness of SCOPE coach supported internet-delivered psychoeducative program using a randomized controlled design in a clinical health care…
- Trial name
- SCOPERCT (NCT03665363)
- Testing
- SCOPE, Self-study
- Where
- Sweden
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Autism Spectrum Disorder
A Study to Evaluate the Efficacy and Safety of Lactococcus Lactis KD10 Powder for Improving Autism Spectrum Symptoms in Children With Autism Spectrum Symptoms.
This human study aims to evaluate the efficacy and safety of Lactococcus lactis KD10 powder for improving autism spectrum disorder symptoms in patients with autism spectrum disorder.
- Trial name
- NCT06650644
- Testing
- Lactococcus lactis KD10 (health food)
- Where
- 2 sites in South Korea
- Volunteers
- 48 people
- Sponsor
- Miae Oh
Physical Exercise Condition, Control Condition
Physical Exercise to Reduce Anxiety in Underserved Children With ASD
Anxiety is one of the most frequent comorbidities in children with ASD leading to poor clinical outcomes. Physical exercise has been shown to be a promising and easy to implement intervention for reducing anxiety.
- Trial name
- PETRA (NCT02902952)
- Testing
- Physical Exercise, Control Intervention
- Where
- 2 sites in United States
- Volunteers
- 148 people, healthy volunteers welcome
- Sponsor
- University of California, Irvine
Autism Spectrum Disorder
Impact of Early Interventions on Neurocognitive Profile of Children With Autism Spectrum Disorder
The Early start Denver model (Rogers, 2010; Dawson, 2010) is a developmental and behavioral model that aim to enhance socio-comunicative abilities and also global development of children with Autism spectrum disorder (ASD).
- Trial name
- IDEAEYE (NCT03254264)
- Testing
- Early Start Denver Model, 'as-usual' intervention
- Where
- France
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Hôpital le Vinatier
PTEN Gene Mutation, PTEN Hamartoma Tumor Syndrome
RAD001 and Neurocognition in PTEN Hamartoma Tumor Syndrome
Phosphatase and TENsin homolog (PTEN) gene germline mutations are associated with a spectrum of clinical manifestations characterized by neurocognitive deficits, intellectual disability, autism symptomatology, skin lesions…
- Trial name
- NCT02991807
- Testing
- RAD001
- Where
- 3 sites in United States
- Volunteers
- 46 people
- Sponsor
- Boston Children's Hospital
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