Clinical trials: Children With Autism
Autism Spectrum Disorder
A Multi-site Double-blind Placebo-controlled Trial of Memantine Versus Placebo in Children With Autism (MEM)
This study will attempt to study the effect of memantine, on memory, and motor praxis/expressive language skills in children with autism.
- Trial name
- NCT01372449
- Testing
- Memantine
- Where
- 2 sites in United States
- Volunteers
- 23 people
- Sponsor
- Evdokia Anagnostou
ASD, Child Behavior Problem
Autism and Disruptive Behavior Trial
Investigators seek to transform the delivery of health care to children with autism spectrum disorder (ASD) and behavioral health problems (and their families) by developing an innovative tiered set of interventions.
- Trial name
- NCT04204226
- Testing
- Social Worker, Autism Behavioral Health Navigation (ABHN), Social work + ABHN
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- Children's Hospital of Philadelphia
Autism Spectrum Disorder
A Longitudinal Follow-up Imaging Study on Children and Adolescents With Autism Spectrum Disorder
The significance of this project is the first longitudinal study to investigate the changes of neurocognitive functions of children and adolescents with ASD and to identify the potential neuroimaging endophenotype (biomarkers)…
- Trial name
- NCT02719067
- Where
- Taiwan
- Volunteers
- 140 people
- Sponsor
- National Taiwan University Hospital
Autism, Autism Spectrum Disorder
Evaluating Efficacy of a Digital Game Therapeutic for Children With Autism
The following study aims to assess the efficacy of the game-based digital therapeutic, GuessWhat, in improving adaptive socialization skills in children with Autism Spectrum Disorder (ASD).
- Trial name
- NCT06058104
- Testing
- Charades based mobile digital therapeutic
- Where
- United States
- Volunteers
- 1,000 people
- Sponsor
- Stanford University
Autism, Smell Dysfunction
Ultramicronized Palmitoylethanolamide for Smell, Taste in Children With Autism Spectrum Disorder.
Autism Spectrum Disorder (ASD) is frequently associated with atypical sensory processing across visual, auditory, olfactory, and gustatory domains, variably affecting quality of life and requiring personalized treatment.
- Conditions
- Autism, Smell Dysfunction, Taste Alterations, Sensorial Disturbance
- Trial name
- SmeTasAu (NCT07631455)
- Testing
- supplement (Paidinil® HD, Epitech Group SpA, Saccolongo, Padova, Italy) containing 12% umPEA, Lactobacillus and Omega Fatty acids
- Where
- Italy
- Volunteers
- 80 people
- Sponsor
- University of Campania Luigi Vanvitelli
Autism, Attention Deficit Hyperactivity Disorder
Transcranial Photobiomodulation Therapy for the Treatment of Autistic Traits in Children and Adolescents With ADHD
An open label trial to assess the safety and efficacy of transcranial photobiomodulation (tPBM) in improving autistic traits in ADHD youth.
- Trial name
- NCT04569058
- Testing
- Transcranial Photobiomodulation
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- Massachusetts General Hospital
Irritability Associated With Autism Spectrum Disorder
Extension Study of Pimavanserin in Irritability Associated With Autism Spectrum Disorder
52-week, open-label extension study of double-blind study ACP-103-069 to determine the long-term safety and tolerability of pimavanserin for the treatment of irritability associated with ASD in children and adolescents (aged 5 to…
- Trial name
- NCT05555615
- Testing
- Pimavanserin
- Where
- 48 sites in United States, Australia and 6 more
- Volunteers
- 209 people
- Sponsor
- ACADIA Pharmaceuticals Inc.
Autism Spectrum Disorder, Attention Deficit Hyperactivity Disorder
Eye Tracking as a Predictor of Methylphenidate Response in Autism With ADHD
The overall goal of this research is to use neurophysiological measures to profile strengths and deficits for Attention Deficit Hyperactivity Disorder co-morbidity in Autism Spectrum Disorder to clarify diagnosis and to predict…
- Trial name
- SAT (NCT02874690)
- Testing
- Methylphenidate
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Autism Spectrum Disorder, Child Autism
Assessment of the Benefit of Teleconsultations for Children With Autism Spectrum Disorders
The purpose of this study is to determine whether Teleconsultation would a)be effective and cost-effective by increasing the proportion of patients with Autism Spectrum Disorders having a correct follow-up, and less…
- Trial name
- NCT02996708
- Where
- 6 sites in France
- Volunteers
- 102 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Autism Spectrum Disorder
A Trial of Sertraline in Young Children With Autism Spectrum Disorder
This study is a control trial of sertraline (Zoloft) in children aged 2 to 5 years old inclusive with Autism Spectrum Disorder. The trial is six months long, and each participant will receive a series of tests at both the…
- Trial name
- Sert2 (NCT02385799)
- Testing
- Sertraline
- Where
- United States
- Volunteers
- 58 people
- Sponsor
- Randi J. Hagerman, MD
Autism Spectrum Disorder
Heart Voice: Starry Journey - A Digital ACT Intervention for ASD Caregivers
The goal of this clinical trial is to evaluate the effectiveness of the "Heart Voice: Starry Journey" program, a family-centric and Acceptance and Commitment Therapy (ACT)-based digital narrative intervention, in improving…
- Trial name
- NCT07319455
- Testing
- ACT-Based Mobile Application Intervention
- Where
- China
- Volunteers
- 52 people
- Sponsor
- Harbin Medical University
Autism Spectrum Disorder
MOTOR PROFICIENCY IN RELATION TO COGNITIVE FUNCTIONS AND SEVERITY IN CHILDREN WITH AUTISM SPECTRUM DISORDERS
To investigate the relationship between cognitive function, the severity of autism spectrum disorder (ASD), and the development of fine and gross motor skills in children with ASD
- Trial name
- NCT06889233
- Testing
- measuring cognitive functions, severity of autism , gross and fine motor skills
- Where
- Egypt
- Volunteers
- 64 people
- Sponsor
- Cairo University
Autism Spectrum Disorder
Preliminary Effects of the CO-OP Approach in Children With Autism Spectrum Disorder
Autism spectrum disorder may affect children's participation in daily occupations through difficulties related to motor planning, problem-solving, attention, behavioral regulation, and sensory processing.
- Trial name
- NCT07717853
- Testing
- Cognitive Orientation to Daily Occupational Performance Approach
- Where
- Turkey (Türkiye)
- Volunteers
- 10 people
- Sponsor
- Atlas University
Autism Spectrum Disorder, Depression
Feasibility and Efficacy of rTMS in Depression in Patients With Autism Spectrum Disorder (ASD)
Depression is a common complication of Autism Spectrum Disorder (ASD): it is four times more prevalent in people with ASD than in the general population.
- Conditions
- Autism Spectrum Disorder, Depression, Major Depressive Episode (MDE)
- Trial name
- DEPASS'R (NCT07258914)
- Testing
- rTMS, rTMS treatment with intermittent Theta Burst (ITBS)
- Where
- France
- Volunteers
- 25 people
- Sponsor
- Hospital Center Guillaume Régnier
Autism, Autism in Children
Developing a Novel Therapy for Aversive Sensory Experiences in Autism
The goal of this study is to assess whether a new psychological treatment can lead to changes in sensory experiences in autistic young people.
- Trial name
- NCT06682858
- Testing
- Group Cognitive Behavioural Therapy
- Where
- United Kingdom
- Volunteers
- 25 people
- Sponsor
- King's College London
Autism Spectrum Disorder
Folinic Acid as a Treatment for Autism Spectrum Disorder in Children
Autism spectrum disorder (ASD) is a neurodevelopmental condition that affects communication, behavior, and social interaction in children. Current treatments are limited and mainly focus on managing symptoms.
- Trial name
- FOLIN-A (NCT07630506)
- Testing
- Folinic Acid
- Where
- Singapore
- Volunteers
- 184 people
- Sponsor
- KK Women's and Children's Hospital
Autism Spectrum Disorder
Role of Folinic Acid in Improving the Adaptive Skills and Language Impairment in Children With Autism Spectrum Disorder
No such study has been conducted in Pakistan so the primary objective of this study was to determine the role of folinic acid in improving the speech and adaptive skills while secondary objective was improvement of stereotype…
- Trial name
- NCT05013164
- Testing
- Folinic Acid
- Where
- Pakistan
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Nishtar Medical University
Autism, Autism Spectrum Disorder
Optimizing Outcomes for Young Autistic Children
The overarching goal of the proposed study is to: (a) determine how best to sequence two parent-mediated interventions: a social communication intervention (Project ImPACT, Improving Parents as Communication Teachers) and a…
- Trial name
- NCT05926687
- Testing
- Social Communication, Disruptive Behavior, Social Communication + Reduce Frequency
- Where
- United States
- Volunteers
- 184 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Autism Spectrum Disorders
Replication of the The Multi-Media Social Skills Project for Adolescents With Autism Spectrum Disorders
The objective of this study is to validate a social skills training program manual for adolescents (ages 13-17) with Asperger's Syndrome or high functioning autism.
- Trial name
- NCT01836965
- Testing
- Social Skills Intervention
- Where
- United States
- Volunteers
- 155 people, healthy volunteers welcome
- Sponsor
- Milton S. Hershey Medical Center
Autism Spectrum Disorder
Acceptability and Efficacy of a Culturally Adapted, Low-Frequency Parent-Mediated Early Start Denver Model (ESDM) Versus Standard Care in Young Children With Autism
Early intervention is effective in improving developmental outcomes of children on the autism spectrum. However, cultural and contextual factors may influence parental acceptability of treatment models, highlighting a need for…
- Trial name
- NCT07840586
- Testing
- Early Start Denver Model
- Where
- Singapore
- Volunteers
- 58 people
- Sponsor
- National University Hospital, Singapore
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