Clinical trials: Children With Disabilities
Mental Disorders
Effects of Emotion on Episodic Memory in Typically Developing Children and Children With Williams-Beuren Syndrome
It's well established in the literature that emotional events are more likely to be remembered than neutral events. Although this Emotional Enhancement of Memory (EEM) has been well demonstrated in the adult literature, little is…
- Trial name
- EEM-TAdev (NCT03688516)
- Testing
- Manipulation of valence and modality, Spatial and recognition memory, Source and content memory
- Where
- France
- Volunteers
- 280 people, healthy volunteers welcome
- Sponsor
- Hôpital le Vinatier
Development Coordination Disorder, Motor Coordination or Function; Developmental Disorder
The Effects of Yoga on Sensory, Motor, Cognitive Skills, and Perceived Stress in Children With Developmental Coordination Disorder
This clinical study aims to investigate the effects of yoga on children with Developmental Coordination Disorder (DCD). DCD is a condition that can make it difficult for children to perform everyday activities, as it affects…
- Conditions
- Development Coordination Disorder, Motor Coordination or Function; Developmental Disorder, Sensory Integration Disorder, Perceived Stres Level
- Trial name
- NCT07547514
- Testing
- Yoga intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Fenerbahce University
Down Syndrome
Effects of Orofacial Therapy and Therapeutic Yoga in Children With Down Syndrome
The study aims to compare the effects of orofacial therapy and therapeutic yoga on swallowing, sleep habits, and quality of life in children with Down syndrome.
- Trial name
- NCT06352151
- Testing
- Routine Physiotherapy Group, Orofacial Treatment Group, Therapeutic Yoga Group
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Hasan Kalyoncu University
Quality of Life
Assessment of Oral Health Related Quality of Life After Full Mouth Rehabilitation Under GA
To assess Oral health related quality of life (OHRQOL) after full mouth rehabilitation under GA in a group of Egyptian children with special healthcare need.
- Trial name
- NCT03497312
- Testing
- full mouth rehabilitation
- Volunteers
- 14 people
- Sponsor
- Cairo University
Silver Russell Syndrome, Prader-Willi Syndrome
Aromatase Inhibitor in Bone Maturation, Children With Silver Russell or Prader-Willi Syndrome
There is currently no drug with pediatric marketing authorization capable of limiting the advance in bone maturation of children with aggressive adrenarche.
- Trial name
- ANASILPRA (NCT01520467)
- Testing
- Anastrozole
- Where
- France
- Volunteers
- 27 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Developmental Delay
Effects of Power Ball on Proximal Muscle and Refractive Errors in Developmental Delay.
When a child does not meet developmental milestones at the anticipated times, it is referred to as having a developmental delay. These benchmarks cover social, emotional, cognitive, physical, and communication abilities.
- Trial name
- NCT06461572
- Testing
- conventional therapy, conventional therapy along with standard therapy and stability exercises.
- Where
- Pakistan
- Volunteers
- 32 people
- Sponsor
- Riphah International University
Major Depression, Mania
Reliability and Validity of the MINI International Neuropsychiatric Interview for Children and Adolescents (MINI-KID)
The primary aims of this study are to assess: 1. The inter-rater and test-retest reliability of the MINI-KID 2. The validity of the standard MINI-KID interview in relation to the parent rated pencil/paper version (MINI-KID-P) and…
- Conditions
- Major Depression, Mania, Anxiety Disorders, Psychotic Disorder
- Trial name
- NCT00579267
- Testing
- MINI-KID
- Where
- United States
- Volunteers
- 230 people, healthy volunteers welcome
- Sponsor
- University of South Florida
Microcephaly, Hyperkinesis With Developmental Delay
Intensive Therapy for Children With Microcephaly, Hyperkinetic Movements, or Global Developmental Delay
This trial will consist of a clinical series of up to 50 children with Global Developmental Delay and concomitant microcephaly or hyperkinetic movements.
- Conditions
- Microcephaly, Hyperkinesis With Developmental Delay, Global Developmental Delay
- Trial name
- NCT04816175
- Testing
- Acquire Therapy
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Virginia Polytechnic Institute and State University
Dyslexia
Study of Hierarchy of Afferents in Postural Control of Children With Dyslexia
The purpose is to determine the hierarchy of sensory afferents according to different forms of dyslexia in children. The secondary purpose is to determine sensitive and sufficiently specific posturographic indexes for standard…
- Trial name
- EQUIDYS (NCT02879786)
- Testing
- Posturographic tests, Questionnaire of motion sickness susceptibility
- Where
- France
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Central Hospital, Nancy, France
Intellectual Disabilities (F70-F79)
Virtual Reality for Dental Anxiety in Children With Mild Intellectual Disability
Virtual reality (VR) is a promising non-pharmacological approach to reduce dental anxiety in children with neurodevelopmental disorders.
- Trial name
- VR-MID (NCT07249359)
- Testing
- Virtual Reality Distraction - immersive VR software delivered through Meta Quest 3® headset during dental procedure, Control: Monitor-Based Distraction
- Where
- Italy
- Volunteers
- 56 people
- Sponsor
- Oasi Research Institute-IRCCS
Developmental Delay Disorder, Repetitive Transcranial Magnetic Stimulation (rTMS)
Repetitive Transcranial Magnetic Stimulation Combined With Language Training for Language Disorders in Children With Global Developmental Delay
This study explores a safe and effective new approach to improve language function in children with Global Developmental Delay (GDD).
- Conditions
- Developmental Delay Disorder, Repetitive Transcranial Magnetic Stimulation (rTMS), Global Developmental Delay, Language Disorders in Children
- Trial name
- NCT07369960
- Testing
- Transcranial magnetic stimulation, individualized language training
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Xiangya Hospital of Central South University
Developmental Disability
Oral Health Education for Caregivers of Children With Disabilities
Considering the impact of caregivers' oral health knowledge, attitudes and practices on the oral health of their children; we introduced an educational program to the parents and caregivers of children with developmental…
- Trial name
- NCT03157596
- Testing
- Oral Health Educational Program for Caregivers of Children with developmental disabilities
- Volunteers
- 61 people
- Sponsor
- ElTyeb, Sara Amir Hassan, M.D.
Urologic Diseases, Gastrointestinal Diseases
PACT Programme for Parents of Children With SHCN
This randomised controlled trial aims to determine the efficacy of a 12-week, smartphone-based Prosocial-orientated Acceptance and Commitment Training (PACT) programme plus age-appropriate positive parenting advice on the…
- Conditions
- Urologic Diseases, Gastrointestinal Diseases, Vascular Diseases, Cleft Lip and Palate
- Trial name
- NCT05467527
- Testing
- Prosocial-orientated Acceptance and Commitment Training plus positive parenting advice, Positive parenting advice
- Where
- 2 sites in Hong Kong
- Volunteers
- 196 people
- Sponsor
- Chinese University of Hong Kong
Parent-Child Relations
Effects of Infant Massage on Acceptance, Commitment and Conscience of Influence of Parents With Down Syndrome Babies
This study aims to analyze whether the course of infant massage serves as a tool to improve acceptance, commitment and awareness of influence of parents of babies with Down syndrome.
- Trial name
- NCT03126734
- Testing
- Infant Massage course
- Where
- Spain
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Seville
Down Syndrome, Sleep Disordered Breathing
Healthy Sleep for Children With Down Syndrome
The purpose of this multi-center observational study (utilizing the sites enrolling patients for the Pediatric Adenotonsillectomy Trial for Snoring (PATS) [1U011HL125307-O1A1]) is to gather data regarding children with Down…
- Trial name
- HELP-DS (NCT03922165)
- Testing
- Adenotonsillectomy
- Where
- 6 sites in United States
- Volunteers
- 26 people
- Sponsor
- Brigham and Women's Hospital
Autism, Developmental Delay Disorders
Project EARLY: Engagement, Assessment, Referral, & Linkage for Young Children
Emerging evidence demonstrates that Autism Spectrum Disorder (ASD) can be reliably diagnosed by age two, and that early identification and intervention can improve outcomes.
- Trial name
- NCT02359084
- Testing
- Family Navigation, Conventional Care Management
- Where
- 10 sites in United States
- Volunteers
- 340 people
- Sponsor
- Boston University
Global Developmental Delay
Umbilical Cord Blood Therapy for Global Developmental Delay
This open-label study aims to evaluate the safety and efficacy of autologous or allogeneic umbilical cord blood therapy for children with global developmental delay.
- Trial name
- NCT01769716
- Testing
- Umbilical cord blood transplantation
- Where
- South Korea
- Volunteers
- 14 people
- Sponsor
- MinYoung Kim, M.D.
Developmental Dysphasia, Epileptic Encephalopathy, Childhood-Onset
CNKSR2 Natural History Study
This prospective natural history study is being conducted to define the electroclinical, neurodevelopmental, and behavioral characteristics of CNKSR2 epilepsy aphasia syndrome (EAS) and intellectual disability (ID) in children…
- Conditions
- Developmental Dysphasia, Epileptic Encephalopathy, Childhood-Onset, X-Linked Intellectual Disability
- Trial name
- CNKSR2 (NCT06500260)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of California, San Francisco
Down Syndrome
Exercise Intensity for Down Syndrome Children
The current study aimed to determine the appropriate exercise intensity for the rehabilitation of children with down syndrome.
- Trial name
- NCT05271201
- Testing
- treadmill exercise (mild), treadmill exercise (moderate)
- Where
- Saudi Arabia
- Volunteers
- 34 people
- Sponsor
- Taif University
Micturition Disorder
Prevalence, Etiology and Therapy of Micturition Disorders of Children With a Mental and/or Motoric Disability
Investigation of the prevalence etiology and therapy of micturition disorders of children with a mental and/or motoric disability
- Trial name
- NCT00148005
- Testing
- Questionnaire and micturition and drinking diaries, Clinical and functional examination (uroflowmetry, bladder scan and video-urodynamic examination), Adaptation of the drinking scheme
- Where
- Belgium
- Volunteers
- 250 people
- Sponsor
- University Hospital, Ghent