Clinical trials: China
Ischemic Heart Disease, Cardiac Arrest
Registry of Multicenter Brain-Heart Comorbidity in China
This study is a multi-center, prospective, registry study. This research was supported by the National Key Research and Development Program.
- Conditions
- Ischemic Heart Disease, Cardiac Arrest, Atrial Fibrillation, Heart Failure
- Trial name
- BHC-C (NCT05961748)
- Testing
- Multi-disciplinary assessment
- Where
- 14 sites in China
- Volunteers
- 100,000 people
- Sponsor
- Beijing Tiantan Hospital
Lung Neoplasms
China Lung Cancer Screening (CLUS) Study Version 2.0
Our previous study, china lung cancer screening study version 1.0, had proven that LDCT led to a 74.1% increase in detecting early-stage lung cancer compare to usual care (NCT02898441).
- Trial name
- NCT03975504
- Testing
- Low Dose Computed Tomography, artificial intelligence (AI), autofluorescence imaging (AFI)
- Where
- China
- Volunteers
- 6,000 people, healthy volunteers welcome
- Sponsor
- Shanghai Chest Hospital
Tuberculosis (TB)
Research on Key Interventional Technologies for Controlling the Epidemic in High-prevalence Areas of Tuberculosis in Guangxi, China
The goal of this study is to find out if using mobile vans with advanced technology can help reduce tuberculosis (TB) in rural Guangxi, China. The study will also examine how practical and cost-effective this approach is.
- Trial name
- NCT06702774
- Testing
- Active case finding
- Where
- China
- Volunteers
- 43,067 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Advanced or Metastatic ROS1-Positive Non-Small Cell Lung Cancer
A Study of Lorlatinib in Subjects With ROS1-Positive Non-Small Cell Lung Cancer
A Phase 2, Multi-Center, Open-Label, Single-Arm Study to Evaluate the Efficacy and Safety of Lorlatinib Monotherapy in Crizotinib and Platinum-based Chemotherapy Treated Locally Advanced or Metastatic ROS1-Positive Non-Small Cell…
- Trial name
- NCT05297890
- Testing
- Lorlatinib
- Where
- 31 sites in China
- Volunteers
- 70 people
- Sponsor
- CStone Pharmaceuticals
Epidemiological Investigation, Malocclusion
Epidemiological Investigation of Malocclusion in China
Malocclusion is a kind of craniomaxillofacial complex deformity caused by heredity, environment, bad habits, trauma, inflammation, tumor and aging.
- Trial name
- NCT06352385
- Volunteers
- 19,847 people
- Sponsor
- Shanghai Jiao Tong University School of Medicine
Proliferative Diabetic Retinopathy
25-Gauge Vitrectomy With Ranibizumab or Triamcinolone Acetonide on Proliferative Diabetic Retinopathy in China
Proliferative diabetic retinopathy(PDR) is the leading cause of visual loss in diabetic patients. Operation is an efficient method to treat PDR.
- Trial name
- RaTAPDR (NCT02328118)
- Testing
- Ranibizumab, Triamcinolone Acetonide
- Where
- China
- Volunteers
- 120 people
- Sponsor
- JUNYAN ZHANG
Lung Diseases, Interstitial
A Study to Test How Well a Medicine Called Nintedanib Helps People in China With Progressive Lung Fibrosis
This study in China is open to people with progressive lung fibrosis (chronic fibrosing ILDs with progressive phenotype) who are at least 18 years old.
- Trial name
- NCT05065190
- Testing
- Nintedanib
- Where
- 16 sites in China
- Volunteers
- 81 people
- Sponsor
- Boehringer Ingelheim
Emphysema
REACH SVS Control Patient Cross-Over Study
This is a multicenter, prospective study designed to evaluate performance of the SVS in the REACH SVS control patients. The study is expected to enroll up to 20 patients at up to 12 sites with up to 6 patients per site.
- Trial name
- NCT02914340
- Testing
- Spiration Valve System
- Where
- China
- Volunteers
- 9 people
- Sponsor
- Olympus Corporation of the Americas
Psoriasis
An Investigational Study to Evaluate Experimental Medication BMS-986165 Compared to Placebo in Participants With Plaque Psoriasis (POETYK-PSO-3) in Mainland China, Taiwan, and South Korea
The purpose of this study is to investigate the experimental medication BMS-986165 compared to placebo in participants with moderate to severe plaque psoriasis in mainland China, Taiwan, and South Korea
- Trial name
- POETYK-PSO-3 (NCT04167462)
- Testing
- BMS-986165
- Where
- 34 sites in China, South Korea and 1 more
- Volunteers
- 220 people
- Sponsor
- Bristol-Myers Squibb
Metastatic Castration-resistant Prostate Cancer, Bone Metastases
A Research Called CREDIT Studies How Safe the Study Treatment Radium-223 is and How Well it Works in Chinese Men With Advanced Prostate Cancer That Has Spread to the Bones and Does Not Respond to Treatments for Lowering Testosterone Levels
This is an observational study in which data from Chinese men with metastatic castration-resistant prostate cancer that has spread to the bones and who start Radium-223 therapy is studied.
- Trial name
- CREDIT (NCT05301062)
- Testing
- Radium-223 dichloride (Xofigo, BAY88-8223)
- Where
- China
- Volunteers
- 8 people
- Sponsor
- Bayer
Chronic Obstructive Pulmonary Disease COPD
Realize the Current Situation of COPD Patients in China
This is a multi-centre, prospective, observational study to realize the current situation of COPD patients in China. About 5000 COPD patients will be enrolled from 50 participating sites around China and followed up for one year.
- Trial name
- REAL (NCT03131362)
- Where
- China
- Volunteers
- 5,020 people
- Sponsor
- AstraZeneca
Breast Cancer, Solid Tumor
A Study of TY-302 in Patients With Advanced Solid Tumors
The primary objective of this study is to evaluate the safety and tolerability of TY-302 single and the combination with Tamoxifen in dose-escalation and dose-expansion study.The drugs involved in this study are: TY-302 Tamoxifen
- Trial name
- NCT04433494
- Testing
- TY-302: capsule, 25mg/50mg ; Tamoxifen: tablet,10mg
- Where
- China
- Volunteers
- 60 people
- Sponsor
- TYK Medicines, Inc
HIV-1 Infections
Clinical, Virological and Safety Outcomes of a Lopinavir/Ritonavir-Based Regimen in HIV-1 Infected Patients in Routine Clinical Use in China
This post-marketing observational study is conducted for obtaining data on clinical, biological and virological outcomes, compliance and tolerability of using a lopinavir/ritonavir (LPV/r) -containing regimen for the treatment of…
- Trial name
- NCT01074931
- Testing
- Lopinavir/ritonavir (Kaletra)
- Where
- 5 sites in China
- Volunteers
- 98 people
- Sponsor
- Abbott
Malaria, Arbovirus Infections
Field Evaluation of Plant-based Mosquito Control
Isolated minority communities in China use traditional plant-based methods of mosquito control. This study is evaluating 4 plants used in this way by monitoring mosquitoes entering houses on nights when the plants are being used…
- Trial name
- NCT00116766
- Testing
- anti-mosquito plant use
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- London School of Hygiene and Tropical Medicine
HIV Infections
A Cluster-Randomized Intervention Trial to Improve Quality of Life for HIV-Infected Individuals in Anhui, China
The HIV epidemic in China has reached a phase of exponential growth; the number of new infections has been steadily increasing over the past decade.
- Trial name
- NCT00479141
- Testing
- HIV skills training, Popular Opinion Leaders training
- Where
- China
- Volunteers
- 3,199 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Heathly Subjects
A Phase I Clinical Study of Flonoltinib Maleate Tablets in Healthy Subjects
Evaluate the safety , tolerability and pharmacokinetics of Flonoltinib Maleate tablets in a single increasing dose oral administered to healthy adult Chinese subjects.Subjects will divide into experimental group and placebo…
- Trial name
- NCT06387966
- Testing
- Flonoltinib Maleate Tablets
- Where
- China
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Chengdu Zenitar Biomedical Technology Co., Ltd
Morality, Risk Factor, Sepsis
Mathematical Modeling and Risk Factor Analysis for Mortality of Sepsis
The purpose of this study was to investigate the risk factors for mortality of sepsis and to create mathematical models to predict the survival rate based on electronic health records that extracted from hospital information…
- Conditions
- Morality, Risk Factor, Sepsis, Predictive Model
- Trial name
- NCT03883061
- Testing
- regular medical treatment
- Where
- China
- Volunteers
- 2,000 people
- Sponsor
- Shanghai Tongji Hospital, Tongji University School of Medicine
Mobile Health Intervention to Promote HIV Self-testing
mHealth and HIV Self-testing
The investigators will pilot test an intervention to use a mobile application ("app") to improve HIV self-testing (HST) with high-risk men in China.
- Trial name
- NCT03569462
- Testing
- Mobile "WeChat" intervention, Control condition
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Brown University
Pneumococcal Disease
Pneumoniae Epidemiology Study in China
To determine the proportion of hospitalized pneumonia cases in children aged 60 months or less associated with vaccine-preventable Streptococcus pneumoniae serotypes (4, 6B, 9V, 14, 18C, 19F, 23F).
- Trial name
- NCT00471770
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- Wyeth is now a wholly owned subsidiary of Pfizer
Urolithiasis
Parents' Health-Education Handbook in Preventing Pediatric Urolithiasis Formation
The aim of this study is to estimate the role of Parents' Health-Education Handbook in preventing pediatric urolithiasis. This study is designed as an unmatched clusters randomized intervention trial.
- Trial name
- NCT04284241
- Testing
- Parents'Health-Education Handbook
- Where
- China
- Volunteers
- 2,500 people, healthy volunteers welcome
- Sponsor
- Guohua Zeng