Clinical trials: Chiropractic Manipulation
Patellofemoral Pain Syndrome
Comparison Study of Two Chiropractic Treatment Protocols for Knee Pain Due to Patellofemoral Pain Syndrome
The purpose of this study is to compare outcomes of combined chiropractic care in anterior knee pain patients with patellofemoral pain syndrome.
- Trial name
- NCT00401050
- Testing
- chiropractic manipulative therapy, knee exercises, Graston Instrument Soft Tissue Mobilization (GISTM)
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- Cleveland Chiropractic College
Low Back Pain
Comparison of a Multiple Thrust Instrument to a Single Thrust Instrument in Treating the Low Back
The purposes of this study are to determine if there is a difference between two treatment methods of spine joints that are not moving as they should as determined by tenderness over the spine and activity of the muscles along…
- Trial name
- AECC (NCT01180686)
- Testing
- Activator IV single impulse instrument, Multiple thrust Impulse adjusting instrument
- Where
- United Kingdom
- Volunteers
- 40 people
- Sponsor
- Anglo-European College of Chiropractic
Back Pain
Comparison of Activator Manipulation Versus Manual Side Posture Manipulation in Patients With Low Back Pain
This study compared the treatment effect of Activator Methods Chiropractic Technique (AMCT) and manual Diversified type spinal manipulative therapy in a sample of patients with acute and sub-acute low back pain.
- Trial name
- NCT00497861
- Testing
- Activator Methods Chiropractic Technique
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Cleveland Chiropractic College
Musculoskeletal Equilibrium
Feasibility Study of Short-Term Effects of Chiropractic Manipulation on Older Adults With Impaired Balance
To study the effect of chiropractic care and a specific exercise program on balance in older adults.
- Trial name
- NCT00497510
- Testing
- Chiropractic manipulation
- Where
- 2 sites in United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Cleveland Chiropractic College
Acute Sciatica, Lumbar Disc Herniation
Chiropractic Spinal Manipulative Therapy for Acute Sciatica Secondary to Lumbar Disc Herniation
Comparisons of surgical and non-operative treatment of patients with acute sciatica secondary to lumbar intervertebral disc herniation (AS/LDH) have shown no appreciable difference in outcome.
- Trial name
- NCT01552486
- Testing
- Chiropractic Spinal Manipulative Therapy, Usual Care
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- Vancouver General Hospital
Colon Cancer Stage III, Colon Cancer Stage IV
The Effects of Chiropractic in Adults With Colon Cancer
The main objectives of this single-arm pilot trial are to investigate the feasibility of our protocol in terms of 1) recruitment, 2) adherence, 3) tolerability, 4) acceptability and 5) retention.
- Trial name
- CCX (NCT05310565)
- Testing
- HVLA cervical chiropractic adjustments
- Where
- United States
- Sponsor
- Life University
Acute Neck Pain
Chiropractic Spinal Manipulative Therapy for Acute Neck Pain
Acute neck is very common in the general population and often causes disability over shorter or longer time periods. Unfortunately, the efficacy of chiropractic spinal manipulative therapy (CSMT) and the efficacy of Non-steroidal…
- Trial name
- NCT05374057
- Testing
- Chiropractic spinal manipulative therapy (CSMT), Ibuprofen
- Where
- Norway
- Volunteers
- 320 people
- Sponsor
- University Hospital, Akershus
Vertebral Artery Dissection, Traumatic, Neck Pain
Effects of Spinal Manipulation on Vertebrobasilar and Internal Carotis Arteries in Healthy Population
After lumbar pain, neck pain is the most common cause of patients needing chiropractic care; the second most common cause of spinal manipulation use (1).
- Trial name
- NCT03435159
- Testing
- Doppler Ultrasonography, Manual Chiropractic Spinal Manipulation, Instrumental Chiropractic Spinal Manipulation
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Bahçeşehir University
Metabolic Syndrome
The Effects of Chiropractic in Adults With Metabolic Syndrome
The purpose of this study is to assess the feasibility of our study procedures/protocols and to look at the potential effects of chiropractic care on people with metabolic syndrome.
- Trial name
- MET (NCT05884437)
- Testing
- Chiropractic adjustment
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Life University
Osteoarthritis, Hip
Clinical Assessment of Two Manipulative Protocols in Treatment of Hip Osteoarthritis
Purpose of this study is to examine the effect of chiropractic adjusting (manipulative therapy) and rehabilitation on hip osteoarthritis (hip OA) in older adults.
- Trial name
- NCT00523172
- Testing
- manual or manipulative therapy, Manual / Manipulative Therapy, Supportive Care
- Where
- 3 sites in United States, Australia and 1 more
- Volunteers
- 120 people
- Sponsor
- Cleveland Chiropractic College
Cervicogenic Headache
Is Chiropractic Spinal Manipulative Therapy an Efficient Treatment Option in Cervicogenic Headache
This study will highlight and validate chiropractic spinal manipulative therapy (CSMT) for cervicogenic headache (CEH). If the method proves to be effective, it will provide a new non-pharmacological treatment option for CEH.
- Trial name
- NCT01687881
- Testing
- Chiropractic
- Where
- Norway
- Volunteers
- 19 people
- Sponsor
- University Hospital, Akershus
Weightlifting, Breathing
The Effects of Cervical and Thoracic Manipulation Therapy Applied to Weightlifting Athletes
The effects of manipulation therapy on the autonomic nervous system have been examined in the literature and while no sympathetic or parasympathetic changes were found after upper thoracic manipulation, a decrease in sympathetic…
- Conditions
- Weightlifting, Breathing, Breath Tests, Athlete
- Trial name
- NCT06606795
- Testing
- Spinal Manipulation
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Selcuk University
Cervicogenic Headache
Cervicogenic Headache Dose-Response
This study will determine the number of visits to a chiropractor for spinal manipulation and light massage necessary for the optimal relief of cervicogenic headache (headache with associated neck pain).
- Trial name
- CGH D-R (NCT01530321)
- Testing
- Spinal Manipulation, Light Massage
- Where
- 2 sites in United States
- Volunteers
- 256 people
- Sponsor
- University of Western States
Safety Issues
MIST3: Active Patient Safety Reporting
This study will seek to describe and understand adverse events (AE) severity ratings.
- Trial name
- MIST3 (NCT04161677)
- Where
- United States
- Volunteers
- 161 people, healthy volunteers welcome
- Sponsor
- Parker University
Ankle Inversion Sprain
Changes in the Ankle Range of Motion Following Subtalar Joint Manipulation
The purpose of the study is to determine whether manipulation of the subtalar joint (one of the two joints of the ankle) has an effect on ankle range of motion in a group of ankles that have sustained a subacute inversion ankle…
- Trial name
- NCT00981331
- Testing
- Subtalar joint manipulation
- Where
- 2 sites in Canada
- Volunteers
- 28 people
- Sponsor
- Canadian Memorial Chiropractic College
Athletic Performance, Neuromuscular Adaptations
Squat Jump Performance and Chiropractic Ankle Manipulation
The goal of this clinical trial is to learn if chiropractic ankle manipulation can improve squat jump performance. It will also learn about the relationship among chiropractic ankle manipulation, ankle range of motion, and squat…
- Conditions
- Athletic Performance, Neuromuscular Adaptations, Lower Limb, Chiropractic Manipulation
- Trial name
- NCT07641621
- Testing
- Manual Therapy Procedure: Chiropractic Ankle Manipulation
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Northeast College of Health Sciences
Low Back Pain
Heart Rate Variability Modulation Following a Manipulation in Pain Free Patients Versus Patients in Pain
Background The purpose of this study was to examine the heart rate variability (HRV) in the presence or the absence of pain in the lower back (L5), while receiving chiropractic care.
- Trial name
- NCT00740558
- Testing
- Activator methods technique, Traditional chiropractic adjustment
- Where
- 2 sites in Canada
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Université du Québec a Montréal
Migraine With Aura, Migraine Without Aura
Is Chiropractic Spinal Manipulative Therapy an Efficient Treatment Option for Migraine
This study will highlight and validate chiropractic spinal manipulative therapy (CSMT) for migraine. If the method proves to be effective, it will provide a new non-pharmacological treatment option for migraine.
- Trial name
- NCT01741714
- Testing
- Chiropractic spinal manipulative therapy
- Where
- Norway
- Volunteers
- 104 people
- Sponsor
- University Hospital, Akershus
Headache Disorders
Spinal Manipulation for Treatment of Chronic Headaches
This study will determine the effectiveness of spinal manipulation in reducing pain in people with chronic headaches accompanied by neck pain.
- Trial name
- NCT00246350
- Testing
- massage, spinal manipulation
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- University of Western States
Patient Safety, Manipulation, Spinal
(MIST2)-Part2: AEs Following DC Care at DC Teaching Clinic: Electronic
This study aims to compare different ways to establish severity from patients reporting a new or worsening symptom (adverse event) following a chiropractic treatment at a teaching clinic using an electronic platform.
- Trial name
- MIST2 (NCT03412110)
- Testing
- active surveillance: electronic platform
- Where
- United States
- Volunteers
- 416 people, healthy volunteers welcome
- Sponsor
- Parker University