Clinical trials: Chlorhexidine
Periodontitis, Periodontitis Stage II
Comparative Effects of Two Oral Antiseptics Used as an Adjuvant in the Treatment of Periodontitis
The focus of this study is on two types of mouthwashes - one containing a chlorhexidine (CHX) at 0.2% (CHX), and the other one containing CHX at a lower concentration of 0.12% with cetylpyridinium chloride (CPC).
- Conditions
- Periodontitis, Periodontitis Stage II, Periodontitis Stage III
- Trial name
- NCT06967402
- Testing
- Experimental (chlorhexidine), Control (chlorhexidine with cetylpyridinium chloride)
- Where
- Hong Kong
- Volunteers
- 60 people
- Sponsor
- The University of Hong Kong
Periodontitis, Type 2 Diabetes Mellitus (T2DM)
Para-Probiotic Oral Care in Periodontal Patients With Type 2 Diabetes
This randomized controlled clinical trial aims to evaluate the effectiveness of a para-probiotic-based oral care protocol in improving periodontal health and glycemic control in patients with type 2 diabetes mellitus (T2DM).
- Trial name
- PPDM2 (NCT07069166)
- Testing
- Para-probiotic oral care, Chlorhexidine oral care
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- University of Pavia
Apical Periodontitis
2% Chlorhexidine (CHX) vs CaOH2 (CH) Calcium Hydroxide Paste as an Intracanal Medicament
This is a Pilot Phase III single-blind randomized controlled clinical trial in patients, aged 18 years and older, presenting with symptoms of apical periodontitis.
- Trial name
- NCT03700788
- Testing
- Chlorhexidine, Calcium Hydroxide
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Ventilator Associated Pneumonia
Role of Oral Chlorhexidine Gel in Prevention of Ventilator Associated Pneumonia
The purpose of this study is to determine if oral mucosal application of chlorhexidine gel will prevent the development of ventilator associated pneumonia in children.
- Trial name
- NCT00597688
- Testing
- Chlorhexidine gel
- Where
- India
- Volunteers
- 86 people
- Sponsor
- All India Institute of Medical Sciences
Human Microbiome
Cultures Before and After Decolonization in Community Dwelling Adults With Current S. Aureus Colonization
The investigators propose to study the microbiome of the nose, throat and three skin sites in a population without current exposure to the healthcare environment: 80 community dwelling adults.
- Trial name
- NCT04222699
- Testing
- Mupirocin calcium ointment, 2%, Topical Chlorhexidine, 4%
- Where
- United States
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Device Related Infection, Vascular Access Complication
The IVCare Adaptive Platform Trial
The IVCare trial is a multicentre adaptive platform study evaluating interventions to prevent infections and other complications associated with central venous access devices (CVADs) in patients with newly inserted or existing…
- Conditions
- Device Related Infection, Vascular Access Complication, Device Related Sepsis, Catheter Infection
- Trial name
- NCT07587593
- Testing
- Connectors/Caps Domain - Standard of Care, Curos™, ClearGuard™ HD
- Volunteers
- 2,500 people
- Sponsor
- The University of Queensland
Gingivitis
Effectiveness of Black Tea Mouthwash on Plaque Formation
The study was conducted to measure the effectiveness of Black Tea in reducing the deposits on teeth. It also compares the effect between use of black tea mouthwash and green tea mouthwash to that of chlorhexidine in reducing…
- Trial name
- Blacktea (NCT02545244)
- Testing
- Black Tea, Green Tea, 0.12% Chlorhexidine Mouthwash.
- Where
- India
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Sri Hasanamba Dental College and Hospital
Catheter-Related Infections
Comparison of Chlorhexidine Impregnated Dressing and Standard Dressing
Investigators have designed a single-center randomized controlled trial to compare chlorhexidine gluconate (CHG)-impregnated dressing and standard dressing with respect to their effects on the infection outcomes.
- Trial name
- NCT04794231
- Testing
- Standard dressing, Chlorhexidine gluconate -impregnated dressing group
- Where
- Turkey (Türkiye)
- Volunteers
- 307 people
- Sponsor
- Istanbul Medeniyet University
Gingivitis Infection, Dental Plaque
Chlorhexidine vs Essential Oil Mouthwash for Plaque Control
Dental plaque is a sticky film of bacteria that forms on teeth and can lead to gum disease if it is not removed regularly. Brushing and flossing help control plaque, but many people also use a mouthwash to help clean areas that…
- Trial name
- NCT07822256
- Testing
- Chlorhexidine Gluconate Mouthwash, Essential Oil mouthwash
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Rehman Medical Institute - RMI
Surgical Site Infections, Lumbar Disc Herniation
The Effect of Number of Showers With 4% Chlorhexidine Gluconate on Prevention of Surgical Site Infections
Surgical site infections (SSIs) are the most common type of nosocomial infection in surgical departments. Although lumbar disc herniation (LDH), which is one of the common cases in neurosurgery, is a serious problem affecting…
- Trial name
- SSI (NCT06801275)
- Testing
- 1 shower with 4% chlorhexidine gluconate, 2 shower with 4% chlorhexidine gluconate
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Çanakkale Onsekiz Mart University
Periimplant Diseases, Dental Implant Failure
Microbiological Evaluation of the Effectiveness of Different Surface Decontamination Protocols for Dental Implants
The purpose of this prospective clinical study is to evaluate and compare the effectiveness of different cleaning (decontamination) methods for dental implants affected by peri-implantitis.
- Conditions
- Periimplant Diseases, Dental Implant Failure, Dental Implant Complications
- Trial name
- NCT07529444
- Testing
- Laser Photodynamic Therapy (PDT), GalvoSurge Electrolytic Cleaning, 0.2% Chlorhexidine Gluconate
- Where
- Croatia
- Volunteers
- 90 people
- Sponsor
- University of Zagreb
Abscess
The Effect Of Wound Irrigation With Irrisept™ Delivery System On Abscess Healing In Patients Presenting To The Emergency Department
The purpose of this study is to determine if wound cleansing and irrigation using the IRRISEPT Chlorhexidine Gluconate(CHG)solution, applying a given volume with a pressurized stream, will improve the outcome for infected…
- Trial name
- NCT01302548
- Testing
- IRRISEPT, Usual Care
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- University of Florida
Catheter-Related Infections
Chlorhexidine-Impregnated Sponge Dressing: A Clinical Trial
The purpose of this study is to compare the use of chlorhexidine-gel-impregnated dressing and the transparent polyurethane film dressing as coverage of the site of insertion of central venous catheter, in the evaluation of…
- Trial name
- CISDCT (NCT02472158)
- Testing
- chlorhexidine-gel-impregnated dressing, Polyurethane film dressing
- Where
- Brazil
- Volunteers
- 120 people
- Sponsor
- University of Sao Paulo
Preterm Premature Rupture of Membrane
Vaginal Cleansing With Chlorhexidine Gluconate in Women With Preterm Pre-labor Rupture of Membranes
Randomized controlled trial studying the use of vaginal cleansing with chlorhexidine gluconate for pregnant women with PPROM (preterm pre labor rupture of membranes). The primary outcome will be pregnancy latency.
- Trial name
- NCT04516226
- Testing
- Vaginal cleansing with chlorhexidine gluconate solution
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Albany Medical College
Plaque-Induced Gingivitis
Efficacy of Thymus Vulgaris Mouthwash in the Management of Biofilm-Induced Gingivitis
The goal of this clinical trial is to determine whether a mouthwash made from thyme (Thymus vulgaris) helps improve gum health in people with plaque-induced gingivitis.
- Trial name
- NCT07905456
- Testing
- 0.2% Thymus vulgaris mouthwash, Chlorhexidine 0,12%
- Where
- Iraq
- Volunteers
- 60 people
- Sponsor
- University of Sulaimani
Halitosis
Effect of a Mouthwash Containing Chlorhexidine and Chlorine Dioxide on Halitosis
Halitosis significantly impacts the quality of a patient's life. This randomized, double-blind crossover trial evaluates a mouthwash containing chlorhexidine (0.01%) and chlorine dioxide (0.05%) compared with placebo.
- Trial name
- CHX+CDO (NCT07265102)
- Testing
- CHX 0.01% + CDO 0.05% mouthwash
- Where
- Vietnam
- Volunteers
- 40 people
- Sponsor
- Can Tho University of Medicine and Pharmacy
Plaque Induced Gingival Disease
Role of Herbal Based Mouthwashes in Plaque Control
Herbal medicine has been used for thousands of years. Traditional herbal medicine is used by an estimated 80% of the world's population for primary health care.
- Trial name
- mouthwash (NCT06711263)
- Testing
- Mouthwash Product
- Volunteers
- 80 people
- Sponsor
- Ajman University
Stage II Periodontitis
Virgin Coconut Oil Versus Chlorhexidine Mouthwash in Non-Surgical Periodontal Therapy of Periodontitis Patients. A Randomized Controlled Clinical Trial With Biochemical Assessment.
This randomized controlled clinical trial will evaluate the effect of virgin coconut oil mouthwash compared with chlorhexidine mouthwash as an adjunct to non-surgical periodontal therapy in patients with stage II periodontitis.
- Trial name
- NCT07706387
- Testing
- Non-surgical periodontal therapy, Chlorhexidine mouthwash, Virgin coconut oil mouthwash
- Where
- Egypt
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Caries Class Ii
Effect of Nano Care Gold on Marginal Integrity of Resin Composite
The aim of this study to detect the effect of Nano Care Gold on marginal integrity of resin composite restoration
- Trial name
- NCT03669224
- Testing
- Nano Care Gold, No intervention, Chlorhexidine
- Where
- Egypt
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Cairo University
Diabetic Foot Ulcer
Preventing Diabetic Foot Ulcers Through Cleaner Feet
Foot complications are among the most serious and costly complications of diabetes. People with diabetes have a 10-fold increased risk for a leg or foot amputation compared to those that do not have diabetes.
- Trial name
- NCT03503370
- Testing
- Chlorhexidine
- Where
- United States
- Volunteers
- 175 people
- Sponsor
- VA Office of Research and Development