Clinical trials: Chlorhexidine
Bacteriuria, Intermittent Catheterization
Open Prospective Study on Reduction of Bacteriuria Following Bladder Irrigation With Chlorhexidine
This a prospective, non-controlled, open, multi-center study evaluating the reduction of bacteriuria after bladder irrigation with chlorhexidine in spinal cord injured patients with chronic bacteriuria practicing intermittent…
- Trial name
- NCT01782404
- Testing
- Chlorhexidine
- Where
- 4 sites in Sweden
- Volunteers
- 50 people
- Sponsor
- Wellspect HealthCare
Caries
Antibacterial Effect of Chlorhexidine Added to the Preventive Protocol in Adolescent Special Needs
This study ia conducted to know the antibacterial effect of chlorhexidine on the mouth flora speciallly in adolescent special needs who can't hold the tooth brush properly
- Trial name
- NCT04679558
- Testing
- Chlorhexidine varnish added to the preventive protocol, Preventive protocol
- Where
- Egypt
- Volunteers
- 22 people
- Sponsor
- Cairo University
Intratracheal Intubation, Surgery
Efficacy of Pre-intubation Chlorhexidine Oral Care on Health Outcomes
This single-centre, single-blind, randomised controlled study with parallel-group design was conducted in Yun Ling, Taiwan between May 2019 and August 2019.
- Conditions
- Intratracheal Intubation, Surgery, Anesthesia
- Trial name
- NCT04252469
- Testing
- Oral care
- Where
- Taiwan
- Volunteers
- 210 people
- Sponsor
- National Taiwan University Hospital
Surgical Flaps, Wound Healing
Periodontal Wound Healing With CHX and Hyaluronic Acid
Backround: No data on the adjunctive effects of hyaluronic acid (HA) in a post-surgery, chlorhexidine (CHX) - based plaque control regimen are available.
- Conditions
- Surgical Flaps, Wound Healing, Gingiva
- Trial name
- CHX+HA+ADS (NCT03465670)
- Testing
- CHX, CHX+HA+ADS
- Where
- Italy
- Volunteers
- 37 people
- Sponsor
- University Hospital of Ferrara
Omphalitis
Topical Application of Chlorhexidine to the Umbilical Cord for Prevention of Omphalitis and Neonatal Mortality in Rural District of Pakistan
The investigators hypothesize that application of 4% Chlorhexidine to the cord stump and meticulous hand washing by primary health care providers of newborn infants will reduce the incidence of Omphalitis and thereby Neonatal…
- Trial name
- Chlorhexidine (NCT00682006)
- Testing
- 4% Chlorhexidine, Hand washing Soap
- Where
- Pakistan
- Volunteers
- 9,800 people
- Sponsor
- Aga Khan University
Infection of Catheter Exit Site, Catheter Related Infection
Alcoholic Chlorhexidine Compared to Povidone Iodine to Limit Perineural Catheter Colonisation
Implementation of perineural catheters may lead to infection by catheter colonization. Catheters may be colonized by the bacteria present on the skin.
- Trial name
- CHLOVEPI (NCT02950246)
- Testing
- perineural catheterization implementation, 2% alcoholic chlorhexidine, povidon iodine
- Where
- France
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Hôpital Raymond Poincaré
Chronic Gingivitis
Efficacy of Cuminum Cyminum Herbal =Preparation in Inhibition of Plaque and Gingivitis.
Present work was to investigate the possible efficacy of 0.2% cuminum cyminum herbal preparation as an antiplaque and antigingivitis agent when compared with chlorhexidine.
- Trial name
- NCT04767269
- Testing
- Cuminum Cyminum, herbal Mouthwash
- Where
- India
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Maharishi Markendeswar University (Deemed to be University)
Periodontal Diseases
Comparative Evaluation of Propolis Mouthwash With 0.2% Chlorhexidine Mouthwash in Improving the Periodontitis
The goal of this clinical trial is to compare the efficacy of Propolis mouthwash with 0.2% Chlorhexidine mouthwash as an adjunct to mechanical therapy in improving the status of periodontal disease in peri-menopausal women.
- Trial name
- NCT05870059
- Testing
- Propolis mouthwash, Chlorhexidine mouthwash
- Where
- Pakistan
- Volunteers
- 102 people
- Sponsor
- Ziauddin University
Sepsis, Pregnancy
Chlorhexidine Vaginal and Infant Wash in Pakistan
Infection is a major health problem during birth in Pakistan. This study will look at the possibility of using a septic wash to help improve health during birth in Karachi, Pakistan.
- Trial name
- NCT00121394
- Testing
- Chlorhexidine vaginal and infant wash
- Where
- Pakistan
- Volunteers
- 5,008 people, healthy volunteers welcome
- Sponsor
- NICHD Global Network for Women's and Children's Health
Periodontal Diseases, Diabetes Mellitus Type 2
Microbiological Effect of 0.12% Chlorhexidine Digluconate and 0.05% Cetylpyridinium Chloride vs Probiotics (Lactobacillus Reuteri Prodentis) on Porphyromonas Gingivalis.
This randomized non-inferiority clinical trial aims to evaluate the microbiological effect of 0.12% chlorhexidine and 0.05% cetylpyridinium vs.
- Trial name
- NCT07489924
- Testing
- Mouthwash with chlorhexidine and cetylpyridine chloride, Probiotic (Lactobacillus reuteri Prodentis
- Where
- Mexico
- Volunteers
- 20 people
- Sponsor
- Universidad de Colima
Postoperative Pain, Pain, Dental
Influence of Intra Canal Medications on Postoperative Flare-up in Endodontic Re-treatment Cases
Is to evaluate the influence of the calcium hydroxide / chlorhexidine combination and calcium hydroxide alone as an intra-canal medication in postoperative flare-up in two visits endodontic retreatment cases
- Trial name
- NCT03064191
- Testing
- calcium hydroxide chlorhexidine combination, calcium hydroxide intra-canal medicament
- Where
- Egypt
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- rayan rabie dahab
Hand Washing
Optimization of Surgical Hand Preparation Using Sorbectol
Previous studies evaluated the efficacy of the hydroalcoholic solution of 3% digluconate of chlorhexidine, 0.3% potassium sorbate and 70% ethanol, "Sorbectol" (Spanish patent ES 2 784 275 B2) in the surgical hand preparation with…
- Trial name
- NCT06688890
- Testing
- Surgical hand rub with the reference product; n-propanol 60%., Surgical hand rub with the product P1; Sorbectol for 1 min., Surgical hand rub with the product P2; Sorbectol for 3 min.
- Where
- Spain
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Universidad Complutense de Madrid
Surgical Site Infections
Eliminate Risk of Cardiac Surgical Site Events
The purpose of the study is to see if using 2% Chlorhexidine cloths will reduce surgical site infections in patients having elective cardiac surgery.
- Trial name
- ERASE (NCT01425697)
- Testing
- 2% Chlorhexidine Gluconate cloths, Standard of Care preoperative preparation.
- Where
- 4 sites in United States
- Volunteers
- 739 people, healthy volunteers welcome
- Sponsor
- University of Rochester
Effects of Topical Chlorhexidine and Benzidine Spray
To Evaluate the Effect of Chlorhexidine-benzidamine Administration
The use of laryngeal mask (LMA) for the purpose of providing airway safety of patients is a common method in general anesthesia practice.
- Trial name
- NCT03253497
- Testing
- Chlorobenzene Liquid
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Diskapi Yildirim Beyazit Education and Research Hospital
Plaque Score, Gingival Health
Effectiveness of Herbal vs Chlorhexidine Mouthwashes in Improving Oral Health in Schoolchildren
Dental plaque and gingivitis are common oral health problems among school children. Mechanical plaque control, such as tooth brushing, is essential but may be insufficient for maintaining optimal oral hygiene.
- Conditions
- Plaque Score, Gingival Health, Streptococcus Mutans
- Trial name
- NCT07309679
- Testing
- Chlorhexidine Digluconate 0.2% Mouthwash, Pomegranate Peel Extract Mouthwash, Neem Extract Mouthwash
- Where
- Egypt
- Volunteers
- 156 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Corneal Toxicity, Ototoxicity
A Comparison of Infection Rates Between Two Surgical Sites
Does the use of chlorhexidine scrub prior to cutaneous surgery on the face increase the chances of toxicity to the eyes or ears? In addition, does the us eof chlorhexidine scrub on the face prior to cutaneous surgery decrease the…
- Conditions
- Corneal Toxicity, Ototoxicity, Surgical Site Infection
- Trial name
- NCT01263262
- Where
- United States
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Medical Thoracoscopy
Surgical Site Preparation in Subjects Undergoing Medical Thoracoscopy
Medical thoracoscopy is the preferred procedure for performing pleural biopsy in patients with pleural effusions that remain undiagnosed after pleural fluid analysis.
- Trial name
- CAPTAIN (NCT05430308)
- Testing
- Chlorhexidine scrub, Povidone-iodine
- Where
- 2 sites in India
- Volunteers
- 100 people
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Neonatal Mortality, Cord Care
Chlorhexidine Cordcare for Reduction in Neonatal Mortality and Omphalitis
In a community-based controlled trial among children to evaluate if use of 4% Chlorhexidine cleansing solution on umbilical cord of infants in first 10 days of life results in Reduction in neonatal mortality (deaths in first 28…
- Conditions
- Neonatal Mortality, Cord Care, Omphalitis
- Trial name
- CHX-Pemba (NCT01528852)
- Testing
- Chlorhexidine 4%, Control cord cleaning solution
- Where
- Tanzania
- Volunteers
- 36,911 people
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Postoperative Wound Infection
Efficacy Study of Antiseptic Preoperative Scrubs in Prevention of Postoperative Infections
Most cases of infection of clean-contaminated wounds (wounds without gross spillage of organisms from the gastrointestinal tract) are thought to originate from the skin.
- Trial name
- NCT00290290
- Testing
- chlorhexidine-alcohol, Povidone-Iodine
- Where
- 6 sites in United States
- Volunteers
- 849 people
- Sponsor
- Baylor College of Medicine
Alveolar Osteitis
Evaluations of the Effects of Tranexamic Acid and Chlorhexidine Gel on Alveolar Osteitis Incidence
This intervention is the treatment of alveolar osteitis (alveolitis) with different effects, which occurs due to the formation of clot after extraction, which is one of the most common intervals after tooth extraction.98 healthy…
- Trial name
- NCT06435832
- Testing
- Absorbable Gelatin, Chlorhexidine, Tranexamic acid
- Where
- Turkey (Türkiye)
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Recep Tayyip Erdogan University