Clinical trials: Chlorhexidine
Periodontal Diseases
A Comparison of Chlorhexidine and Green Tea Mouthwash in Patients With Gingivitis and Their Salivary Neutrophil and TAC Levels
A Comparison of Chlorhexidine and Green Tea Mouthwash in Patients With Gingivitis and Their Salivary Neutrophil and TAC Levels.
- Trial name
- (1346) (NCT06875440)
- Testing
- CHX mouthwash
- Where
- Iran
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Islamic Azad University, Sanandaj
Healthy
Components of Chlorhexidine Gluconate Dressing
The purpose of this study is to determine the contents of a chlorhexidine-containing dressing after use.
- Trial name
- NCT01112020
- Testing
- CHG Catheter Dressing Patch, Biopatch, Tegaderm CHG
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- C. R. Bard
Surgical Site Infections
Eliminate Risk of Cardiac Surgical Site Events
The purpose of the study is to see if using 2% Chlorhexidine cloths will reduce surgical site infections in patients having elective cardiac surgery.
- Trial name
- ERASE (NCT01425697)
- Testing
- 2% Chlorhexidine Gluconate cloths, Standard of Care preoperative preparation.
- Where
- 4 sites in United States
- Volunteers
- 739 people, healthy volunteers welcome
- Sponsor
- University of Rochester
High Caries Risk Patients
Assessment of Inhibition of Biofilm Formation and Plaque Bacterial Count of Fluoride Varnish Containing Chlorhexidine and Cetylpyridinium Chloride Versus Conventional Fluoride Varnish
Two different Fluoride varnish systems(Fluoride varnish containing Chlorhexidine and Cetylpyridinium Chloride (CPC) and conventional fluoride) will be applied to high caries risk patients to assess their clinical effects on…
- Trial name
- NCT04254835
- Testing
- Cervitec F, Ivoclar Vivadent - Schaan Liechtenstein, Fluor Protector, Ivoclar Vivadent - Schaan Liechtenstein
- Where
- Egypt
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Cairo University
Cardiogenic Shock, Extracorporeal Membrane Oxygenation Complication
Impact of ECMO Cannula Chlorhexidine-impregnated Dressings to Decrease Extracorporeal Membrane Oxygenation-cannula Related Infection Rate
The Dressing-ECMO trial is a prospective, open-label, multicenter, controlled trial randomizing patients who received percutaneous ECMO to cannula chlorhexidine-impregnated dressing vs standard dressing.
- Conditions
- Cardiogenic Shock, Extracorporeal Membrane Oxygenation Complication, Acute Respiratory Distress Syndrome, Infections
- Trial name
- DRESSING-ECMO (NCT05750576)
- Testing
- Chlorhexidine-impregnated dressings, Non impregnated dressings
- Where
- 6 sites in France
- Volunteers
- 270 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Infectious Diseases
Isopropyl Alcohol Against Chlorhexidine - Isopropyl Alcohol as Antiseptics to Prevent Hemoculture's Contamination
The purpose of this study is to determinate if 70% isopropyl alcohol is not inferior preventing contamination of peripheral hemocultures, compared with 2% chlorhexidine in 70% isopropyl alcohol.
- Trial name
- NCT01361997
- Testing
- chlorhexidine in isopropyl alcohol, Isopropyl alcohol
- Where
- Mexico
- Volunteers
- 1,102 people
- Sponsor
- Universidad de Guanajuato
Mouthwash, Chlorhexidine
Evaluation of the Anti-Plaque Effect of a Resveratrol-Based Mouthwash Using a 24-Hour Plaque Re-Growth
Dental plaque is a biofilm that accumulates on tooth surfaces and is a primary factor in the development of gingival inflammation.
- Conditions
- Mouthwash, Chlorhexidine, Biofilm Formation, Periodontal Health
- Trial name
- NCT07393802
- Testing
- Resveratrol-Based Mouthwash, Chlorhexidine Gluconate 0.12 % Mouthwash
- Where
- Iraq
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Baghdad
Wounds and Injuries, Respiratory Failure
Prehospital Ventilator-Associated Pneumonia Prevention Trial
Traumatic injury in rural America is a significant cause of morbidity and mortality, and the challenges of a rural trauma system can put patients at unique risk.
- Conditions
- Wounds and Injuries, Respiratory Failure, Pneumonia, Ventilator-Associated
- Trial name
- P-VAPP (NCT01902446)
- Testing
- Chlorhexidine gluconate
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Nicholas M Mohr
Device Related Infection, Vascular Access Complication
The IVCare Adaptive Platform Trial
The IVCare trial is a multicentre adaptive platform study evaluating interventions to prevent infections and other complications associated with central venous access devices (CVADs) in patients with newly inserted or existing…
- Conditions
- Device Related Infection, Vascular Access Complication, Device Related Sepsis, Catheter Infection
- Trial name
- NCT07587593
- Testing
- Connectors/Caps Domain - Standard of Care, Curos™, ClearGuard™ HD
- Volunteers
- 2,500 people
- Sponsor
- The University of Queensland
Gingivitis, Dental Plaque
Antiplaque, Antigingivitis and Anti-inflammatory Effects of Myrrh Mouthwash
Myrrh-based mouthwash has the potential to be a suitable alternative to the gold standard chlorhexidine mouthwash for dental plaque and gingivitis reduction.
- Trial name
- NCT04723732
- Testing
- Myrrh mouthwash, Chlorhexidine mouthwash, Normal saline
- Where
- Saudi Arabia
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- King Abdulaziz University
Disabilities Multiple
Chance to Avoid New Caries by Adding Chlorhexidine to the Preventive Protocol in Adolescent Special Needs
Adolescent Special need individuals are most need of easy forms of antibacterial agents, so in this study, using chemotherapeutic agents like the newly introduced varnish containing chlorhexidine seems to be a quite promising…
- Trial name
- NCT04485312
- Testing
- preventive protocol, chlorhexidine added to the preventive protocol
- Where
- Egypt
- Volunteers
- 22 people
- Sponsor
- Cairo University
Periimplantitis
Implant Healing Abutment and Chlorhexidine
The work hyposesis is based on the application of a chlorhexidine gel against the non-application on the healing abutments in patients who have received a submerged titanium implant to check its effect on healing and prevention…
- Trial name
- CHX-HA (NCT03142828)
- Testing
- Chlorhexidine
- Where
- Spain
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Universidad de Murcia
Urinary Tract Infections
Chlorhexidine to Prevent Catheter-related Urinary Tract Infection
The study is to investigate whether chlorhexidine (CHG)-based antiseptics is more effective to prevent catheter-related urinary tract infection (CAUTI) among inhospital patients who required Foley catheter insertion.
- Trial name
- NCT05712434
- Testing
- Long Intervention, Mid-length Intervention, Short Intervention
- Where
- Taiwan
- Volunteers
- 30,994 people
- Sponsor
- National Taiwan University Hospital
Port-Wine Stain
Pilot Study to Evaluate the Effect of Multiple Passes on Port Wine Stain Treatments With the Cutera Excel V™ Laser.
Two limitations of single pulse, laser treatment of port-wine stains (PWS) are: (i) hemorrhage and purpura which may lead to post-treatment pigmentation and (ii) the necessity for repeated treatment sessions.
- Trial name
- NCT04103164
- Testing
- Cutera excel V™ Laser
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Denture Stomatitis
Ozonated Water in Treatment of Denture Stomatitis
The effect of Ozonated water on the treatment of oral stomatitis associated with complete denture wearer in comparison to Chlorhexidine mouthwash
- Trial name
- NCT06021847
- Testing
- Ozonated water, Chlorhexidine mouthwash
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- National Research Centre, Egypt
Arterial Catheters, Catheter Related Complication
Skin Glue Versus Suture for Securing Radial Arterial Lines
Prior investigators have evaluated the use of 2-octyl cyanoacrylate (glue) as a method to secure a variety of venous catheters including central/peripheral lines.
- Trial name
- NCT06589284
- Testing
- Silk 0-0 suture covered by chlorhexidine gluconate dressing, 2-octyl cyanoacrylate covered by chlorhexidine gluconate dressing
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- CHRISTUS Health
Gingivitis
Clinical Investigation of PerioGard (Test) Regimen
The objective of this three-month clinical research study is to evaluate the clinical efficacy of the PerioGard (test) regimen (0.45% SnF-HW Toothpaste, CPC-Zinc-Fluoride Mouthwash, Gummy Toothbrush) compared to the control…
- Trial name
- NCT07210138
- Testing
- PeriGuard regimen, Colgate Dental Cream regimen
- Where
- Thailand
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Colgate Palmolive
Mucositis, Gingivitis
Efficacy of 0.12% Chlorhexidine Gluconate for Peri-implant Mucositis and Gingivitis
The purpose of this study is to analyze the efficacy of 0.12% chlorhexidine gluconate as a chemical adjuvant for the treatment of peri-implant mucositis in single implants compared with homologous teeth with gingivitis, in a…
- Trial name
- NCT02639377
- Testing
- Chlorhexidine gluconate
- Volunteers
- 29 people
- Sponsor
- Universidade Federal do Rio Grande do Norte
Periodontal Diseases
In-office and Domiciliary Use of a New Ozonized Gel for the Management of Periodontal Disease
The aim of this study is to evaluate the efficacy of non-surgical periodontal therapy with supportive home oral care for the treatment of periodontal disease.
- Trial name
- NCT05254288
- Testing
- Chlorhexidine, Ozoral gels
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- University of Pavia
Propionibacterium Acnes
BPO vs Hibiclens Soap for Surgical Preparation
This is a randomized trial of benzoyl peroxide soap versus Hibiclens soap for surgical preparation. The objective is to determine whether benzoyl peroxide soap, commonly available in drug stores for over-the-counter acne…
- Trial name
- NCT04021524
- Testing
- Benzoyl Peroxide 10% Bar, Chlorhexidine Gluconate
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Washington