Clinical trials: Chlorhexidine
Oral Bacterial Colonization, Oral Hygiene
Effects of Three Oral Hygiene Protocols on Oral Bacteria in Intensive Care Patients
Patients in intensive care may develop changes in the bacteria found in their mouths. Some of these bacteria can cause infections, and patients who cannot clean their own teeth depend on staff to provide oral care.
- Trial name
- NCT07868549
- Testing
- Mechanical Oral Hygiene, Chlorhexidine, Hexetidine
- Where
- Croatia
- Volunteers
- 86 people
- Sponsor
- University of Zagreb
Evaluate to Effects of Two Antiseptic Products and Showering
CHLORHEXIDINE GLUCONATE AND POVIDONE IODINE
The study was planned to evaluate the effects of two most commonly used antiseptic products and showering on the healing process, such as wound healing and postoperative maternal comfort in cesarean section.
- Trial name
- NCT05953714
- Testing
- incision side cleaning with antiseptic products
- Where
- Turkey (Türkiye)
- Volunteers
- 102 people
- Sponsor
- Sakarya University
Periodontal Pocket, Tooth,Non Vital
Chlorhexidine Intracanal Medicament in Periodontal Healing in Concomitant Endo Perio Lesion With Communication
The aim of this prospective randomized controlled clinical trial is to evaluate the effectiveness of chlorhexidine intracanal medicament along with periodontal treatment in concomitant endodontic periodontal lesions with…
- Trial name
- NCT02627326
- Testing
- open flap debridement
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Aphthous Stomatitis
Hyaluronic Acid in Counteracting Aphthous Stomatitis
Oral mucosal ulcers can determine a real worsening of the quality of life. Conventional therapy usually lasts not less than 2-3 weeks, and carries a high risk of serious side effects; furthermore, ulcers often recur.
- Trial name
- NCT04884464
- Testing
- Hyaluronic acid-based gel, Chlorhexidine Gluconate
- Where
- Italy
- Volunteers
- 49 people
- Sponsor
- University of Urbino "Carlo Bo"
Bacterial Contamination
Effectiveness of Pre-Procedural CPC and Zinc Mouthwash in Reducing Dental Aerosols
This clinical trial evaluates the effectiveness of pre-procedural mouthwashes in reducing bacterial contamination in dental aerosols generated during ultrasonic scaling.
- Trial name
- NCT07880509
- Testing
- 0.09% CPC + Zinc Lactate Mouthwash, 0.2% Chlorhexidine Mouthwash, Water
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Colgate Palmolive
Opioid Use Disorder, Injection Drug Use
A Pilot Study to Evaluate Skin Swabbing With Chlorhexidine to Prevent Skin And Soft Tissue Infections Among People Who Inject Drugs
The study examined chlorhexidine gluconate (CHG) swabs as a skin disinfectant in combination with a single-session safer injection training to prevent skin and soft tissue infections (SSTI) in people who inject drugs.
- Conditions
- Opioid Use Disorder, Injection Drug Use, Skin and Soft Tissue Infections (SSTIs)
- Trial name
- NCT06733506
- Testing
- Chlorhexidine gluconate, Isopropyl Alcohol 70% Topical Application Solution, Skin Prep Before Injecting Recreational/Street Drugs
- Where
- United States
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Gabriel John Culbert
Neonatal Mortality
Community Trial of Newborn Skin and Umbilical Cord Cleansing on Neonatal Mortality in Nepal
Neonatal mortality and morbidity is common in Nepal and the vast majority of women deliver babies at home without a skilled birth attendant.
- Trial name
- NCT00109616
- Testing
- Newborn skin cleansing with 0.25% chlorhexidine solution, Cleansing of umbilical cord with soap and water solution, Cleansing of umbilical cord with 4% chlorhexidine
- Where
- 2 sites in United States, Nepal
- Volunteers
- 17,000 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Staphylococcus Aureus, Colonization, Asymptomatic
Decolonization Efficacy of Polyhexanide vs. Mupirocin
This pilot randomized controlled trial evaluates the feasibility, tolerability, and preliminary efficacy of a decolonization regimen using polyhexanide in reducing Staphylococcus aureus colonization in the preoperative phase of…
- Trial name
- SPADE (NCT06633588)
- Testing
- Polyhexanide, Mupirocin and Chlorhexidine
- Where
- Switzerland
- Volunteers
- 24 people
- Sponsor
- Swiss Paraplegic Research, Nottwil
Plaque Induced Gingival Disease
Mouthwashes for Gingivitis: Comparing a Hydrogen Peroxide-Hyaluronic Acid Mix, Hyaluronic Acid, and Chlorhexidine, A Triple-Blind Clinical Trial
This randomized, triple-blind clinical trial is designed to evaluate the efficacy of four different mouthwash formulations - hydrogen peroxide with hyaluronic acid, hyaluronic acid alone, chlorhexidine, and placebo - in four…
- Trial name
- TRIPLE-G (NCT07031388)
- Testing
- 1-Hydrogen peroxide and hyaluronic acid, 2- Hyaluronic acid, Chlorhexidine
- Where
- Iraq
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Ramziyah Hayder Bakr
Cerebral Palsy, Exercise
A Feasibility Randomised Controlled Trial of an Online Exercise Programme for Adults With Cerebral Palsy
Adults with cerebral palsy (CP) often face challenges in accessing exercise programmes that are appropriate for their needs. Barriers such as limited mobility, a lack of tailored options, and restricted access to physiotherapy…
- Conditions
- Cerebral Palsy, Exercise, Adults, Fitness
- Trial name
- NCT06983782
- Testing
- Exercise and education programme, control group
- Where
- Ireland
- Volunteers
- 47 people
- Sponsor
- Royal College of Surgeons, Ireland
Gingivitis
"The Efficacy of Acacia Catechu Mouthrinse as Antiplaque and Antigingivitis Agent in Fixed Orthodontic Appliance Patients.
To study effect of acacia catechu a herbal extract;as antipaque and antigingivitis agent in patients with fixed orthodontic appliances.This study is a double blind randomized controlled trial.
- Trial name
- NCT02154594
- Testing
- Acacia catechu, Chlorhexidine gluconate, Distilled water
- Where
- India
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Tatyasaheb Kore Dental College
Apical Periodontitis, Necrotic Primary Molars
Comparative Evaluation of Antimicrobial Efficacy, Clinical and Radiographic Success of Calcium Hydroxide, Chlorhexidine, and Modified Triple Antibiotic Paste in Different Combination Forms As Intracanal Medicaments Against Enterococcus Faecalis in Primary Teeth
Comparing between different intracanal medications with different combination forms of Modified Triple Antibiotic Paste, Calcium Hydroxide and Chlorehexidine, regarding antimicrobial efficacy through bacterial reduction count of…
- Conditions
- Apical Periodontitis, Necrotic Primary Molars, Periapical Pathosis of Primary Molars
- Trial name
- NCT06625645
- Testing
- Modified triple antibiotic paste (TAP) mixed with chlorehexidine, Modified Triple Antibiotic Paste mixed with saline, Calcium Hydroxide mixed with chlorohexidine Intracanal medication
- Volunteers
- 32 people
- Sponsor
- Mahy Abdel Raouf Aly Kamar
Dental Plaque
A Protocol for the Use of Chlorhexidine Gluconate Saturation for the Reduction of Dental Biofilm Formation on Polymethylmethacrylate Restoration
Chlorhexidine gluconate (CHX), as an anti plaque agent, is commonly used with a variety of products. In this study we, the investigators at Hadassah Medical Organization, intend to examine the efficacy of a single dip in CHX of…
- Trial name
- NCT00259181
- Testing
- saturation of polymethylmethacrylate with chlorhexidine gluconate to reduce in vivo plaque formation
- Where
- Israel
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Neonatal Sepsis, Neonatal Mortality Rate
Chlorhexidine Skin Application for Prevention of Infection in Infants Weighing <1500 g at Birth
Purpose of this study is determine if skin application of chlorhexidine at birth would reduce infection in infants weighing <1500 g at birth.
- Trial name
- CAPS (NCT01723501)
- Testing
- 0.25% chlorhexidine, sterile water
- Where
- 3 sites in India
- Sponsor
- All India Institute of Medical Sciences
Periprosthetic Joint Infection
Microbial Growth in Operative Splash Basins During Total Joint Arthroplasty
The usage of splash basins in the setting of total knee arthroplasty and total hip arthroplasty presents a risk of contamination and subsequent periprosthetic joint infection.
- Trial name
- NCT04274517
- Testing
- Sterile Water, 3.5% Betadine, 0.05% Chlorhexidine Gluconate
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Southern California
Periodontitis, Periodontitis Stage I
Chlorhexidine and Zinc in Non-Surgical Periodontal Therapy
Periodontitis is a chronic inflammatory disease affecting the supporting structures of the teeth and is associated with both local tissue destruction and systemic inflammatory responses.
- Conditions
- Periodontitis, Periodontitis Stage I, Periodontitis Stage II
- Trial name
- CHX-Zn (NCT07517991)
- Testing
- Chlorhexidine and zinc application, Scaling and root planing with distilled water
- Where
- Turkey (Türkiye)
- Volunteers
- 44 people
- Sponsor
- Ataturk University
Cancer
EXCEL: Technology and Exercise Adherence
Exercise adherence and maintenance in the EXCEL program supported with a smart phone application: A pilot randomized controlled trial
- Trial name
- NCT04790578
- Testing
- ZoeInsights Application, EXCEL Exercise Class
- Where
- Canada
- Volunteers
- 140 people
- Sponsor
- University of Calgary
Chlorhexidine
Dressing Impregnated With Chlorhexidine and Vancomycin for the Prophylaxis of Central Venous Catheter-related Infections - a Randomized Trial
You are being invited as a volunteer to participate in the study "Dressing impregnated with chlorhexidine and vancomycin for the prophylaxis of central venous catheter-related infections." The objective is to evaluate the…
- Trial name
- Dressing RCT (NCT07001527)
- Testing
- Chlorhexidine
- Where
- Brazil
- Volunteers
- 516 people
- Sponsor
- Hospital Universitario Evangelico de Curitiba
Gingivitis, Periodontitis
Efficacy of a Mouthwash Containing Propolis
Characterization of green propolis and development of mouthwash containing propolis to control plaque and gingivitis. A Phase I.
- Conditions
- Gingivitis, Periodontitis, Plaque, Inflammation
- Trial name
- PRO (NCT01750801)
- Testing
- Propolis, chlorhexidine
- Where
- Brazil
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Federal University of Minas Gerais
Gingivitis, Gingivitis and Periodontal Diseases
Evaluation of the Effect of a Toothpaste Containing 0.3% Chlorhexidine in Subjects With Established Dental Plaque and Gingivitis
This is a Phase III, one-center, parallel group, double blind, clinical study to evaluate the effect of a toothpaste containing 0.3% chlorhexidine in subjects with established dental plaque and gingivitis.
- Conditions
- Gingivitis, Gingivitis and Periodontal Diseases, Gingival Disease, Dental Plaque
- Trial name
- CHX TP (NCT06732466)
- Testing
- Chlorhexidine toothpaste, Toothbrush
- Where
- Brazil
- Volunteers
- 80 people
- Sponsor
- Colgate Palmolive