Clinical trials: Chlorhexidine, open to volunteers
Oral Mucosal Disorder
Effects of Chlorhexidine Gluconate, Ozonated Water and Hypochlorous Acid Solutions Used in the Oral Care of Patients Supported by Mechanical Ventilation on the Integrity of the Oral Mucosa
The purpose of this clinical trial is to learn whether ozonated water and hypochlorous acid solution can restore the integrity of the oral mucosa.
- Trial name
- NCT06942026
- Testing
- Control 1
- Where
- Turkey (Türkiye)
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Aydin Adnan Menderes University
Gingivitis, Dental Plaque
Clear Aligner Cleaning: Brushing, Chlorhexidine, and BlueM Effects on Oral Microbial Ecology and Periodontal Indices
This randomized crossover study will assess how three aligner-cleaning methods affect early supragingival oral microbial ecology and periodontal health in adults using clear aligners.
- Trial name
- NCT07307716
- Testing
- Mechanical toothbrushing (fluoride toothpaste), Chlorhexidine mouthwash (0.2%), Oxygen-based cleanser
- Where
- Saudi Arabia
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Riyadh Elm University
Intracanal Medicament
Comparison of Inter-appointment Pain Reduction During Root Canal Treatment in Symptomatic Apical Periodontitis by Using Intracanal Medicaments; Chlorhexidine Gel and Single Antibiotic Paste Nitrofurantoin
This study is being conducted to find out which of two medications-Chlorhexidine Gel or Nitrofurantoin-works better in reducing pain between root canal treatment visits.
- Trial name
- NCT07198919
- Testing
- Chlorhexidine gel, Nitrofurantoin 100 MG
- Where
- Pakistan
- Volunteers
- 220 people
- Sponsor
- Altamash Institute of Dental Medicine
Halitosis, Mouth Disease
Efficacy of Resveratrol Containing Mouthwash in Reducing Halitosis Related Porphyrymonas Gingivalis.
The aim of the study: To assess the efficacy of antioxidant (resveratrol) mouthwash in reducing the level of p. gingivitis and oral malodor over 7 day period among undergraduate dental student patients from Mustansiriyah…
- Conditions
- Halitosis, Mouth Disease, Plaque Induced Gingival Disease, Bleeding Gum
- Trial name
- NCT06882564
- Testing
- resveratrol mouthwash, Chlorhexidine mouthwash (0.2%)
- Where
- Iraq
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Al-Mustansiriyah University
Stage II Periodontitis
Virgin Coconut Oil Versus Chlorhexidine Mouthwash in Non-Surgical Periodontal Therapy of Periodontitis Patients. A Randomized Controlled Clinical Trial With Biochemical Assessment.
This randomized controlled clinical trial will evaluate the effect of virgin coconut oil mouthwash compared with chlorhexidine mouthwash as an adjunct to non-surgical periodontal therapy in patients with stage II periodontitis.
- Trial name
- NCT07706387
- Testing
- Non-surgical periodontal therapy, Chlorhexidine mouthwash, Virgin coconut oil mouthwash
- Where
- Egypt
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Plaque Accumulation, Gingival Inflammation
Triphila Mouthwash Effect as Anti-plaque and Anti-gingivitis in Children
The study aim to to assess the antiplaque and antigingivitis efficacy of Triphala mouthwash versus chlorhexidine mouthwash among children.
- Trial name
- NCT07016659
- Testing
- 0.12% Chlorhexidine Mouthwash ( Hexitol ), Triphila mouthwash
- Where
- Egypt
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Cairo University
Arthroplasty Shoulder, Periprosthetic Joint Infection
Optimizing Infection Prophylaxis Prior to Shoulder Surgery
The goal of this interventional study is to determine the amount of skin C. acnes reduction with increased pressure during the chlorhexidine gluconate, brand name ChloraPrep, application.
- Trial name
- NCT06464770
- Testing
- Chlorhexidine Gluconate
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Washington
Plaque, Dental, Antimicrobial
Anticariogenic Effect of Moringa Oleifera Mouthwash Compared to Chlorhexidine Mouthwash
Moringa oleifera (MO) is an extraordinary nutritious vegetable tree with high medicinal value for its antibacterial properties. Formulation of various natural dental remedies from this plant and their testing for their…
- Conditions
- Plaque, Dental, Antimicrobial, Mouthwash, Cytotoxicity
- Trial name
- NCT04575948
- Testing
- Moringa Oleifera, Chlorhexidine mouthwash, Base formula
- Volunteers
- 90 people
- Sponsor
- Misr International University
Gingivitis
Effectiveness of Oil Pulling Using Oils in Comparison With Mouthwash for Gingivitis
The goal of this clinical trial is to learn if daily oil pulling with coconut oil or sesame oil works as effectively as a standard mouthwash to treat gum swelling and redness (gingivitis) in adults aged 18 to 55 years.
- Trial name
- NCT07892235
- Testing
- coconut oil, Sesame Oil, 0.2% Chlorhexidine Mouthwash
- Where
- Pakistan
- Volunteers
- 45 people
- Sponsor
- Bahria University
Periodontal Diseases
A Comparison of Chlorhexidine and Green Tea Mouthwash in Patients With Gingivitis and Their Salivary Neutrophil and TAC Levels
A Comparison of Chlorhexidine and Green Tea Mouthwash in Patients With Gingivitis and Their Salivary Neutrophil and TAC Levels.
- Trial name
- (1346) (NCT06875440)
- Testing
- CHX mouthwash
- Where
- Iran
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Islamic Azad University, Sanandaj
Mouthwash, Chlorhexidine
Evaluation of the Anti-Plaque Effect of a Resveratrol-Based Mouthwash Using a 24-Hour Plaque Re-Growth
Dental plaque is a biofilm that accumulates on tooth surfaces and is a primary factor in the development of gingival inflammation.
- Conditions
- Mouthwash, Chlorhexidine, Biofilm Formation, Periodontal Health
- Trial name
- NCT07393802
- Testing
- Resveratrol-Based Mouthwash, Chlorhexidine Gluconate 0.12 % Mouthwash
- Where
- Iraq
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Baghdad
Device Related Infection, Vascular Access Complication
The IVCare Adaptive Platform Trial
The IVCare trial is a multicentre adaptive platform study evaluating interventions to prevent infections and other complications associated with central venous access devices (CVADs) in patients with newly inserted or existing…
- Conditions
- Device Related Infection, Vascular Access Complication, Device Related Sepsis, Catheter Infection
- Trial name
- NCT07587593
- Testing
- Connectors/Caps Domain - Standard of Care, Curos™, ClearGuard™ HD
- Volunteers
- 2,500 people
- Sponsor
- The University of Queensland
Neurogenic Bladder, Urinary Retention
Effect of Chlorhexidine Gluconate Bladder Instillations in Patients With Chronic Suprapubic Catheters on Unplanned Healthcare Encounters and Quality of Life
The goal of this clinical trial is to evaluate the feasibility and tolerability of 0.05% Chlorhexidine Gluconate (CGH) bladder instillations in an outpatient setting at the time of suprapubic catheter (SPC) exchange in patients…
- Trial name
- NCT06163469
- Testing
- Bladder instillation with Irrisept
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Yale University
Critically Ill, Acute Respiratory Failure
The EXCEL Registry of Patients Requiring ECMO
ECMO is associated with significant costs, risks and requires specialist training and expertise. EXCEL is a novel, high-quality, detailed prospective registry of patients requiring ECMO in Australia and New Zealand.
- Conditions
- Critically Ill, Acute Respiratory Failure, Acute Heart Failure, Cardiac Arrest
- Trial name
- NCT03793257
- Where
- 29 sites in Australia, New Zealand
- Volunteers
- 3,000 people
- Sponsor
- Australian and New Zealand Intensive Care Research Centre
Cancer, Prostate Cancers
Sustainable Implementation of the EXCEL Exercise Oncology Program Across Canada
EXCEL will provide online and, where feasible, in-person exercise programs to individuals living with and beyond cancer (ILWBC).
- Conditions
- Cancer, Prostate Cancers, Breast Cancers, Colon Cancer
- Trial name
- EXCEL (NCT06960291)
- Testing
- Group Exercise Classes
- Where
- 5 sites in Canada
- Volunteers
- 740 people
- Sponsor
- University of Calgary
Nasal Septal Perforation
Oral Mucosal Grafting for Nasal Septal Perforation Repair
This study will assess how often a hole in the nasal septum (the wall separating the two sides of the nose), closes completely after surgical repair using tissue taken from the lining of the patient's own mouth.
- Trial name
- NCT07902856
- Testing
- Nasal Septal Perforation Repair With an Autologous Oral Mucosal Graft
- Where
- 3 sites in Spain
- Volunteers
- 46 people
- Sponsor
- Instituto de Investigación Sanitaria de la Fundación Jiménez Díaz
Periodontitis, Periodontitis Stage II
Comparative Effects of Two Oral Antiseptics Used as an Adjuvant in the Treatment of Periodontitis
The focus of this study is on two types of mouthwashes - one containing a chlorhexidine (CHX) at 0.2% (CHX), and the other one containing CHX at a lower concentration of 0.12% with cetylpyridinium chloride (CPC).
- Conditions
- Periodontitis, Periodontitis Stage II, Periodontitis Stage III
- Trial name
- NCT06967402
- Testing
- Experimental (chlorhexidine), Control (chlorhexidine with cetylpyridinium chloride)
- Where
- Hong Kong
- Volunteers
- 60 people
- Sponsor
- The University of Hong Kong
Extraction Sites After Removal and Bone Replacement Grafting at Extraction Sockets of Dentally Hopeless Single-rooted Teeth
To Compare Post-Extraction Use of a Novel Ethylenediaminetetraacetic Acid (EDTA) Post-operative Mouth Rinse and Daily Use EDTA Mouth Rinse and Standard 0.12% Chlorhexidine (CHX) Post-operative Mouth Rinse and Daily Use Essential Oil (EO) Mouth Rinse.
This study will compare commercially available, commonly used mouth rinses (0.12% chlorhexidine (CHX) vs. Ethylenediaminetetraacetic acid (EDTA)) for immediate post-operative and daily antiseptic use after tooth extraction and…
- Trial name
- NCT07191262
- Testing
- 0.12% CHX and Essential Oil mouthrinse, 2.6% EDTA and 0.2% EDTA mouth rinse
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Bladder Cancer, Urinary Tract Infection
Chlorhexidine Antiseptic Irrigation of the Bowel Segment During Radical Cystectomy and Urinary Diversion
This is a single arm, interventional pilot study of using chlorhexidine irrigation intra-operatively and post-operatively among patients undergoing radical cystectomy with urinary diversion.
- Trial name
- NCT06689176
- Testing
- Irrisept® Antimicrobial Wound Lavage
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Oral Bacterial Colonization, Oral Hygiene
Effects of Three Oral Hygiene Protocols on Oral Bacteria in Intensive Care Patients
Patients in intensive care may develop changes in the bacteria found in their mouths. Some of these bacteria can cause infections, and patients who cannot clean their own teeth depend on staff to provide oral care.
- Trial name
- NCT07868549
- Testing
- Mechanical Oral Hygiene, Chlorhexidine, Hexetidine
- Where
- Croatia
- Volunteers
- 86 people
- Sponsor
- University of Zagreb