Clinical trials: Chlorhexidine Gel
Bone Resorption, Bacteria Caused Disease
0.2% Chx Gel vs Implant Bacterial Contamination
The objective of this human randomized, double blind, placebo-control (RDBPC) study is to evaluate the efficacy of a 0.2% chlorhexidine (CHX) gel on reducing bacterial load and peri-implant inflammation at implant-abutment…
- Trial name
- NCT03431766
- Testing
- 0.20% chlorhexidine gel
- Where
- Italy
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- G. d'Annunzio University
Impacted Mandibular Third Molar, Postoperative Wound Healing
Chlorhexidine Gel After Wisdom Tooth Surgery: A Split-Mouth Randomized Trial
This study evaluates whether placing 0.2% chlorhexidine gel into the tooth socket after lower wisdom tooth surgery improves gum healing, reduces bacteria on surgical stitches, and decreases postoperative pain, swelling, and…
- Conditions
- Impacted Mandibular Third Molar, Postoperative Wound Healing, Postoperative Pain, Postoperative Swelling
- Trial name
- NCT07895251
- Testing
- Chlorhexidine 0.2% Gel
- Where
- Vietnam
- Volunteers
- 25 people
- Sponsor
- University of Medicine and Pharmacy at Ho Chi Minh City
Surgery, Multiorgan Failure
The Influence of Nursing Technique Applied at the Central Venous Catheter Insertion Site Upon the Incidence of Infection
Assessing the impact of the nursing technique applied at the insertion site of the central venous catheter using hydrophilic methacrylate gel (HMG) and 2% Chlorhexidine (CHG) upon the incidence of inflammatory complications when…
- Conditions
- Surgery, Multiorgan Failure, Haematologic Disease
- Trial name
- NCT03875352
- Testing
- CHG technique, HMG technique
- Where
- Czechia
- Volunteers
- 221 people
- Sponsor
- University Hospital Ostrava
Healthy, Saliva
Antibacterial Effect and Substantivity of a New Chlorhexidine and Cymenol Gel on Oral Biofilm and Saliva
The objective of this project was to compare the immediate antimicrobial effect and in situ substantivity of a new 0.20% chlorhexidine (CHX) gel and cymenol with the current CHX gel formulation on dental plaque biofilm and…
- Conditions
- Healthy, Saliva, Biofilms
- Trial name
- NCT06437262
- Testing
- 0.20% CHX gel on saliva, 0.20% CHX and Cymenol gel on saliva, 0.20% CHX gel on oral biofilm
- Where
- Spain
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Santiago de Compostela
Chronic Generalized Periodontitis
Moxifloxacin in Situ Gel to Treat Periodontal Pocket.
In this Randomized clinical trial locally delivered moxifloxacin in situ gel was evaluated as an adjunct to scaling and root planing for efficacy in the treatment of chronic periodontitis and for short-term effects on the…
- Trial name
- NCT02016157
- Testing
- Moxifloxacin
- Where
- India
- Volunteers
- 5 people
- Sponsor
- Sri Hasanamba Dental College and Hospital
Stage II Grade B Periodontitis
Active Oxygen Gel vs Chlorhexidine Gel in Stage II Grade B Periodontitis
This randomized controlled clinical trial will evaluate the effectiveness of locally delivered active oxygen gel and chlorhexidine gel as adjuncts to scaling and root planing in the treatment of stage II grade B…
- Trial name
- NCT07840716
- Testing
- Active oxygen gel, Chlorhexidine gel
- Volunteers
- 60 people
- Sponsor
- Kafrelsheikh University
Periodontal Diseases
In-office and Domiciliary Use of a New Ozonized Gel for the Management of Periodontal Disease
The aim of this study is to evaluate the efficacy of non-surgical periodontal therapy with supportive home oral care for the treatment of periodontal disease.
- Trial name
- NCT05254288
- Testing
- Chlorhexidine, Ozoral gels
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- University of Pavia
Necrotic Pulp
Post Operative Pain and Level of Endotoxins With Calcium Hydroxide and Calcium Hydroxide Mixed With Chlorhexidine in Treating Necrotic Teeth
The aim of this prospective in vivo randomized clinical trial to evaluate influence of combination of calcium Hydroxide (CALCIPAST Paste, Poland) and chlorhexidine Gel 2% (Gluco-Chex 2%, Cerkamed, Poland) in comparison to calcium…
- Trial name
- NCT03009006
- Testing
- Chlorhexidine 2% gel - Calcium Hydroxide Paste - Non-Setting, Calcium Hydroxide Paste - Non-Setting
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Cairo University
Periodontal Diseases
The Effect of an Antioxidant Gel Compared to Chlorhexidine Gel During the Soft Tissue Healing Process: A Randomized Controlled Clinical Trial
This study aims to evaluate the comparative impact of chlorhexidine and antioxidant gel on postoperative biomarkers following SRP.
- Trial name
- Antiox-SRP (NCT06894667)
- Testing
- Antioxidant gel, Antimicrobial gel
- Where
- Kuwait
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Kuwait University
Stage II, Grade B Periodontitis, Chronic Periodontitis
Metformin Versus Chlorhexidine Gel as Adjuncts to Scaling and Root Planing in Stage II Grade B Periodontitis
This clinical trial is designed to evaluate two locally delivered gels, metformin and chlorhexidine, as adjunctive therapies to scaling and root planing (SRP) in patients with Stage II, Grade B periodontitis.
- Trial name
- MET-CHX Perio (NCT07215156)
- Testing
- Arm 1 Scaling and Root Planing (SRP), Arm 2 Metformin Gel 1% (locally delivered), Arm 3 Chlorhexidine Gel 0.2% (locally delivered)
- Volunteers
- 60 people
- Sponsor
- Kafrelsheikh University
Periodontitis, Hyaluronic Acid
Adjunctive Use Of A Novel Hyaluronic Acid/Chlorhexidine Gel In The Non Surgical Treatment Of Periodontitis
General Objective : To evaluate the outcome of non surgical periodontal therapy with local drug delivery adjunct to scaling and root planning Specific Objective : To determine the effect of intra-pocket application of hyaluronic…
- Conditions
- Periodontitis, Hyaluronic Acid, Chlorhexidine
- Trial name
- NCT05682833
- Testing
- Non surgical periodontal therapy
- Where
- United Arab Emirates
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Sharjah
Plaque Induced Gingivitis
Topical Chlorhexidine and Metronidazole Gels for Gingival Inflammation
This randomized controlled clinical trial was undertaken to evaluate and compare the effectiveness of chlorhexidine gluconate gel (1%) alone and a combination gel containing chlorhexidine gluconate (0.5%) with metronidazole…
- Trial name
- NCT07776197
- Testing
- Chlorhexidine Gluconate Gel 1%, Chlorhexidine Gluconate 0.5% + Metronidazole 1.5% Gel
- Where
- India
- Volunteers
- 120 people
- Sponsor
- H.P. Government Dental College and Hospital Shimla
Periodontal Pocket
Comparative Evaluation of Bromelain-Quercetin Gel With Chlorhexidine Gel as Subgingival Local Drug Delivery Following Scaling and Root Planing In Stage I /II and Grade B Periodontitis - Randomized Control Clinical Trail
Comparative Evaluation of Bromelain-Quercetin Gel With Chlorhexidine Gel as Subgingival Local Drug Delivery Following Scaling and Root Planing In Stage I /II and Grade B Periodontitis - Randomized Control Clinical Trail
- Trial name
- NCT06775392
- Testing
- bromelain-quercetin gel, chlorhexidine gel, SRP
- Where
- India
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Krishnadevaraya College of Dental Sciences & Hospital
Peri-Implantitis
Clinical Efficacy of Hybenix vs Chlosite Gels in Peri-implantitis
The present study is a randomized clinical trial (RCT). Patients responding to the inclusion criteria will be included. The following peri-implant indexes will be collected: Bleeding On Probing, Gingival Bleeding Index, Marginal…
- Trial name
- NCT06083246
- Testing
- Hybenix gel, Chlosite gel
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- University of Pavia
One-Piece Dental Implant, Bone-Level Implant
Inflammatory Biomarkers, Microbial Findings, and Clinical Characteristics Before and After Treatment of Peri-Implant Mucositis Around One-Piece and Two-Piece Dental Implants
The goal of this clinical study was to learn whether the design of a dental implant affects how the gums around it respond to treatment of peri-implant mucositis, an early and reversible inflammation of the soft tissue around a…
- Conditions
- One-Piece Dental Implant, Bone-Level Implant, Two-Piece Dental Implant, Nonsurgical Mechanical Debridement
- Trial name
- 1PvsBL (NCT07892313)
- Testing
- Nonsurgical Mechanical Debridement With 1% Chlorhexidine Gel
- Where
- Turkey (Türkiye)
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Cuneyt Asim Aral
Gingivitis
Comparative Evaluation of Chlorhexidine, Metronidazole and Combination Gels on Gingivitis
Patient presenting to the dental clinic with gingivitis and fulfilling the inclusion criteria will be included in the study after taking informed consent. Participants will be divided into three groups.
- Trial name
- NCT03142607
- Testing
- Metronidazole gel, Chlorhexidine Gluconate
- Where
- Pakistan
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Aga Khan University
Peri-implant Mucositis
Chlorhexidine Gel and Peribioma Periogel Use in Peri-implant Mucositis Sites: a Split-mouth Randomized Clinical Trial.
The aim of this study is to evaluate the efficacy of non-surgical periodontal therapy with supportive home oral care for the treatment of peri-implant mucositis.
- Trial name
- NCT04899986
- Testing
- Chlorhexidine and Biorepair gel and toothpaste application, Standard oral hygiene
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- University of Pavia
Traumatic Oral Ulceration, Orthodontic Treatment
Comparison of Hyaluronic Acid and Chlorhexidine Gels for Traumatic Oral Ulcers During Fixed Orthodontic Treatment
This randomized controlled trial aims to compare the effectiveness of topical hyaluronic acid gel and chlorhexidine gel in the management of traumatic oral ulcers that develop following placement of fixed orthodontic appliances.
- Conditions
- Traumatic Oral Ulceration, Orthodontic Treatment, Orthodontic Appliances, Fixed, Oral Mucosal Ulceration
- Trial name
- HYCHO-TOU (NCT07709455)
- Testing
- Hyaluronic Acid gel, Chlorhexidine gel
- Where
- Pakistan
- Volunteers
- 30 people
- Sponsor
- Dow University of Health Sciences
Extraction Socket Healing
Assessment of Topical Application of Chitosan 0.2% Chlorhexidine Gel on Wound Healing in Diabetic Patients
Despite efforts to prevent postoperative discomfort, immediate side effects of surgical extraction of lower molars include bleeding at the site of extraction, inflammation, pain, and alveolar osteitis especially in diabetic…
- Trial name
- NCT07429812
- Testing
- Surgical extraction of the offending tooth will be performed under local anesthesia using inferior alveolar nerve block technique with buccal mucosa infiltration, make an incision on the gingival tis
- Where
- Saudi Arabia
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Tanta University
Peri-implant Mucositis
Efficacy of a Xanthan-based Chlorhexidine Gel in the Treatment of Peri-implant Mucositis
The peri-implant mucositis is an inflammatory and reversible lesion that surrounds the peri-implant mucosa without loss of supporting bone, clinically characterized by bleeding on gentle probing.
- Trial name
- NCT07047261
- Testing
- Adjunctive use of Xanthan-Chlorexidine based gel
- Where
- Italy
- Volunteers
- 182 people
- Sponsor
- University of Turin, Italy