Clinical trials: Chloride Disorder
Chronic Obstructive Pulmonary Disease
An Efficacy Study of BCS Clearing the Oral Colonized Bacterium in Hospitalized Patients With COPD
The purpose of study is to evaluate the efficacy and safety of Benzalkonium Chloride Solution clearing the oral colonized bacterium in hospitalized patients with COPD.
- Trial name
- NCT02269800
- Testing
- Benzalkonium chloride solution, Normal saline
- Volunteers
- 60 people
- Sponsor
- Lustre Pharmaceutical Lab Co., Ltd
Renal Insufficiency
Tetraspan 6 Percent (%) Combined With Sterofundin ISO Versus Albumin 5 Percent (%) Combined With Sodium Chloride (NaCL)
This investigational study will investigate two different volume replacement regimes in patients suffering from compromised renal function.
- Trial name
- NCT00936247
- Testing
- HES 130/0.42 + electrolyte solution, Albumin + electrolyte solution
- Where
- 2 sites in Germany
- Volunteers
- 2 people
- Sponsor
- B. Braun Melsungen AG
Inverse Psoriasis, Sebopsoriasis
Efficacy of Aerosal® in the Treatment of Inverse Psoriasis and Sebopsoriasis
The purpose of this study is to evaluate the efficacy of Aerosal® compared to placebo in the prognosis of inverse psoriasis or sebopsoriasis present for at least one year
- Trial name
- NCT01574872
- Testing
- Halotherapy
- Where
- Italy
- Sponsor
- Tecno Sun SRL
Onychomycosis/Onycholysis and Tinea Pedis
Safety and Pharmacokinetics of Terbinafine Hydrogen Chloride (HCl) Nail Lacquer in Patients With Onychomycosis
In this study, the safety and pharmacokinetics of 10 % terbinafine hydrogen chloride (HCl) nail lacquer wre investigated by comparison with vehicle control and 1% terbinafine cream
- Trial name
- NCT00691184
- Testing
- Terbinafine Hydrochloride, Terbinafine
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- NexMed (U.S.A.), Inc. (subsidiary of Apricus Biosciences, Inc.)
Cystic Fibrosis
Study of Denufosol Inhalation Solution in Patients With Mild to Moderate Cystic Fibrosis Lung Disease
The purpose of this trial is to evaluate the effects of a single dose of denufosol versus placebo on mucociliary clearance in patients with mild to moderate CF lung disease
- Trial name
- NCT00425165
- Testing
- denufosol tetrasodium (INS37217) Inhalation Solution
- Volunteers
- 6 people
- Sponsor
- Merck Sharp & Dohme LLC
Sleep Apnea, Obstructive
Efficacy of Aerosal® in the Treatment of Sub-Obstructive Adenotonsillar Hypertrophy and Related Diseases
The purpose of this study is to evaluate the efficacy of Aerosal® compared to a placebo treatment in the prognosis of sub-obstructive adenotonsillar hypertrophy present for at least six months.
- Trial name
- NCT01574885
- Testing
- Halotherapy
- Where
- Italy
- Volunteers
- 45 people
- Sponsor
- Tecno Sun SRL
Dermatitis, Atopic
WAL 801 CL Dry Syrup in Pediatric Atopic Dermatitis Patients
The safety and efficacy of WAL 801 CL (epinastine hydrochloride) Dry Syrup in the treatment of atopic dermatitis in children was evaluated and plasma drug concentrations were measured.
- Trial name
- NCT02182570
- Testing
- WAL 801 CL dry syrup
- Volunteers
- 62 people
- Sponsor
- Boehringer Ingelheim
Pneumonia
Study to Evaluate the Efficacy and Safety of Intravenous Infusion With Nemonoxacin Malate Sodium Chloride
The purpose of this study is to Evaluate the Efficacy, safety and pharmacokinetics of Intravenous Nemonoxacin Compared with Intravenous Moxifloxacin in Adult Patients with community-acquired pneumonia (CAP).
- Trial name
- NCT01944774
- Testing
- Nemonoxacin 500 mg, Nemonoxacin 650 mg, Moxifloxacin 400 mg
- Where
- 2 sites in China, Taiwan
- Volunteers
- 207 people
- Sponsor
- TaiGen Biotechnology Co., Ltd.
Spinal Cord Injuries
Study to Determine Pharmacodynamic Effects and Pharmacokinetics of KUC 7483 CL in Patients With Spinal Cord Injury and Neurogenic Detrusor Overactivity
Study to investigate pharmacodynamic effects and pharmacokinetics of KUC 7483
- Trial name
- NCT02259751
- Testing
- KUC 7483 CL
- Volunteers
- 26 people
- Sponsor
- Boehringer Ingelheim
Diabetes Mellitus, Type 2
Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Multiple Rising Doses of BI 187004 in Patients With Type 2 Diabetes Mellitus
To investigate safety, tolerability, pharmacokinetics and pharmacodynamics of BI 187004 following multiple dose administration over 14 days.
- Trial name
- NCT01874483
- Testing
- BI 187004
- Where
- Germany
- Volunteers
- 71 people
- Sponsor
- Boehringer Ingelheim
Pulmonary Disease, Chronic Obstructive
Efficacy and Safety of 4 Weeks Treatment With Inhaled BI 1744 CL in Japanese Patients With COPD
The primary objective of this study is to determine the optimum dose(s) of BI 1744 CL inhalation solution delivered by the Respimat inhaler once daily for 4 weeks in Japanese patients with chronic obstructive pulmonary disease…
- Trial name
- NCT00824382
- Testing
- BI 1744 CL 2 µg, BI 1744 CL 5 µg, BI 1744 CL 10 µg
- Where
- 48 sites in Japan
- Volunteers
- 328 people
- Sponsor
- Boehringer Ingelheim
Schizophrenia
Long-Term Real-World Safety of Cobenfy in Adults With Schizophrenia
This study will evaluate the long-term real-world safety of xanomeline-trospium chloride in adults with schizophrenia receiving routine clinical care in the United States.
- Trial name
- NCT07783373
- Testing
- xanomeline-trospium chloride, Oral antipsychotics
- Where
- United States
- Volunteers
- 3,000 people
- Sponsor
- Bristol-Myers Squibb
Dermatitis, Atopic
WAL 801 CL Dry Syrup in Paediatric Atopic Dermatitis Patients
Study to investigate the safety and efficacy of WAL 801 CL Dry Syrup on pruritus associated with paediatric atopic dermatitis in comparison with that of Ketotifen Fumarate Dry Syrup and to confirm the appropriateness of dosage of…
- Trial name
- NCT02182557
- Testing
- WAL 801 CL Dry Syrup, Ketotifen Fumarate Dry Syrup
- Volunteers
- 162 people
- Sponsor
- Boehringer Ingelheim
Cochlear Hearing Loss
Safety and Performance of HiRes Ultra/Ultra 3D Cl Mid-Scala Electrodes in Adults With Severe-to-profound Hearing Loss
This is a prospective study designed to evaluate the safety and performance of the HiRes Ultra Cl HiFocus MS Electrode and HiRes Ultra 3D Cl HiFocus MS Electrode (Ultra X) under normal conditions of use as it is approved for this…
- Trial name
- NCT04610112
- Testing
- Cochlear implantation
- Where
- 3 sites in Germany
- Volunteers
- 30 people
- Sponsor
- Advanced Bionics AG
Pulmonary Disease, Chronic Obstructive
Determining Optimal Free Dose Combination of Tiotropium Bromide and BI 1744 CL in Chronic Obstructive Pulmonary Disease (COPD)
The primary objective of this study is to determine the optimum once daily dose of BI 1744 CL and tiotropium in free dose combination (delivered by the Respimat inhaler) after four week treatment in patients with COPD.
- Trial name
- NCT01040403
- Testing
- olodaterol (BI 1744) low, low tiotropium bromide, olodaterol (BI 1744) high
- Where
- 33 sites in Canada, Germany and 2 more
- Volunteers
- 233 people
- Sponsor
- Boehringer Ingelheim
Chronic Obstructive Pulmonary Disease
Study of Trospium Chloride Inhalation Powder (TrIP) in Patients With Chronic Obstructive Pulmonary Disease
To assess the effect of a single dose of TrIP on pulmonary function in patients with COPD
- Trial name
- NCT00465959
- Testing
- trospium chloride inhalation powder (TrIP)
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Endo USA Inc., a Keenova Therapeutics Company
Schizophrenia
Effectiveness and Adverse-effect Switch Evaluation of Xanomeline and Trospium Chloride (KarXT)
The purpose of this study is to describe real-world treatment patterns, effectiveness and adverse events of adults diagnosed with schizophrenia that have initiated xanomeline and trospium chloride (KarXT) treatment in the United…
- Trial name
- NCT07379827
- Testing
- Xanomeline and trospium chloride (KarXT)
- Where
- 55 sites in United States
- Volunteers
- 1,500 people
- Sponsor
- Bristol-Myers Squibb
Sore Throat Due to a Common Cold
Efficacy and Safety of a Sore Throat Lozenge Containing Lidocaine and Cetylpyridinium Chloride in Patients With Sore Throat Due to a Common Cold.
This study will compare the efficacy and safety of a single dose of a lidocaine 8 mg + cetylpyridimium chloride (CPC) 2 mg lozenge with a single dose of a lidocaine 1 mg + CPC 2 mg lozenge in the treatment of sore throat due to a…
- Trial name
- NCT01265446
- Testing
- Lidocaine 8mg + CPC 2mg, Lidocaine 1mg + CPC 2mg
- Where
- Germany
- Volunteers
- 250 people
- Sponsor
- Novartis
Hard-to-heal Wounds, Diabetic Foot Ulcer
Clinical Investigation of Sorbact® Dressings
The main purpose of this exploratory clinical investigation is to study the binding of bacteria and fungi from hard-to-heal wounds to the DACC-coated dressings.
- Conditions
- Hard-to-heal Wounds, Diabetic Foot Ulcer, Venous Leg Ulcer, Pressure Ulcer
- Trial name
- NCT05089890
- Testing
- Sorbact® Compress, Sorbact® Gel Dressing, Sorbact® Ribbon Gauze
- Where
- Sweden
- Volunteers
- 30 people
- Sponsor
- ABIGO Medical AB
Pulmonary Disease, Chronic Obstructive
Effect of Treatment BI 1744 CL (5 and 10 mcg) Versus Placebo on Exercise Endurance Time During Constant Work Rate Cycle Ergometry II
To compare the effects of BI 1744 CL versus placebo on exercise tolerance after 6 weeks of treatment in patients with Chronic Obstructive Pulmonary Disease.
- Trial name
- NCT01040793
- Testing
- Olodaterol (BI 1744), Olodaterol (BI1744)
- Where
- 19 sites in Austria, Belgium and 3 more
- Volunteers
- 157 people
- Sponsor
- Boehringer Ingelheim