Clinical trials: Cholangiopancreatography
Post-ERCP Pancreatitis
Tacrolimus as Prophylaxis of Post-ERCP Pancreatitis
The goal of this clinical trial is to learn if a single intravenous dose of tacrolimus, given before an ERCP procedure (an endoscopic procedure of the bile ducts and pancreas), can prevent post-ERCP pancreatitis (PEP) in adults…
- Trial name
- TacroProph (NCT07781722)
- Testing
- Tacrolimus
- Where
- Netherlands
- Volunteers
- 520 people, healthy volunteers welcome
- Sponsor
- Amsterdam UMC, location VUmc
Cholangiopancreatography, Endoscopic Retrograde, Choledocholithiasis
Explore the Effects and Mechanisms of ERCP and EST on Biliary Microecology
The objective of this observational study is to explore the structure of biliary flora in normal people, explore the dynamic impact of ERCP and EST on biliary microecology, study the marker flora, metabolites and functional genes…
- Conditions
- Cholangiopancreatography, Endoscopic Retrograde, Choledocholithiasis, Gallstones
- Trial name
- NCT05592795
- Testing
- Whether ERCP or EST is carried out
- Where
- 3 sites in China
- Volunteers
- 75 people
- Sponsor
- Qi-Yong Li
Pancreatitis, Endoscopic Retrograde Cholangiopancreatography
Effect of Papillary Epinephrine Spraying on Post-ERCP Pancreatitis in Patients Received Rectal Indomethacin
Acute pancreatitis is the most common and feared complication of ERCP, occurring after 1% to 30% of procedures. It accounts for substantial morbidity and represents a substantial cost to health-care systems.
- Trial name
- NCT03057769
- Testing
- Papillary epinephrine spraying, Papillary saline spraying, Indomethacin
- Where
- 10 sites in China
- Volunteers
- 3,300 people
- Sponsor
- Air Force Military Medical University, China
Obstructive Jaundice
Outcome of Carbon Dioxide Versus Air Insufflations During Endoscopic Retrograde Cholangiopancreatography (ERCP)
To assess the safety and efficacy of CO2 insufflations during ERCP 1. Primary objective: To assess the patient's symptoms, abdominal pain and abdominal distension post procedure (ERCP) in the study group. 2.
- Trial name
- NCT01321203
- Where
- India
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Asian Institute of Gastroenterology, India
Biliary Obstruction
Cost Analysis for Endoscopic Retrograde Cholangiopancreatography (ERCP)
The purpose of the study is to determine if endoscopist notification of accessory cost results in altered resource utilization related to the total cost and number of accessories used in ERCP.
- Trial name
- ERCP (NCT02127229)
- Testing
- Endoscopist informed of cost per procedure
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Oklahoma
Endoscopic Retrograde Cholangiopancreatography (ERCP), Miniforceps Biopsy
Comparison of Dual-lumen Catheter-guided Mini-forceps Biopsy and Brush Cytology with Vacuum Aspiration in Suspicious Biliary Strictures
In this randomized crossover trial involving patients with indeterminate biliary strictures, we aimed to compare the diagnostic performance of the dual-lumen catheter-guided miniforceps biopsy (CMB) device with that of brush…
- Conditions
- Endoscopic Retrograde Cholangiopancreatography (ERCP), Miniforceps Biopsy, Biliary Strictures, Brush Cytology
- Trial name
- NCT06612931
- Testing
- Dual-lumen catheter-guided mini-forceps biopsy is performed first, Biliary brush cytology with vacuum aspiration is performed first
- Where
- China
- Volunteers
- 112 people
- Sponsor
- Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine
Malignant Distal Biliary Obstruction
EUS-Guided Biliary Drainage in Patients With Inoperable Malignant Distal Biliary Obstruction and Failed ERCP: a Prospective Feasibility Multicenter Trial
This research is being done to study the safety and feasibility of recruiting patients eligible for EUS-guided biliary drainage (EGBD). Our goal is to prospectively study safety and effectiveness of this procedure.
- Trial name
- NCT01889953
- Testing
- EUS-guided biliary drainage
- Where
- 13 sites in United States, India and 3 more
- Volunteers
- 96 people
- Sponsor
- Johns Hopkins University
Biliary and Pancreatic Diseases, Endoscopic Retrograde Cholangiopancreatography (ERCP)
A 2×2 Factorial Randomized Controlled Trial for ERCP
To investigate the effects of propofol vs. cyclopropofol and sufentanil vs. esketamine on intraoperative hypoxemia and hypotension in elderly patients undergoing ERCP, as well as the interaction between these two factors.
- Trial name
- NCT07584902
- Testing
- Anesthesia induction using propofol+sufentanil, Anesthesia induction using propofol+esketamine, Anesthesia induction using ciprofol+sufentanil
- Volunteers
- 236 people
- Sponsor
- Gang Chen
Pancreas Neoplasms, Bile Duct Diseases
Intra-ductal Confocal Endomicroscopy for Characterization of Pancreas and Bile Duct Tumor
The endomicroscopy is an adaptation of traditional optical microscopy in the digestive endoscopy. Furthermore, with the integration of a miniaturized laser confocal microscope to a videoendoscope, it's possible to study the…
- Trial name
- EMID (NCT00930410)
- Testing
- Endoscopic Retrograde Cholangio-Pancreatography (ERCP)
- Where
- 2 sites in France, Monaco
- Volunteers
- 50 people
- Sponsor
- Institut Paoli-Calmettes
Post-ERCP Acute Pancreatitis
Lactated Ringers With or Without Rectal Indomethacin to Prevent Post-ERCP Pancreatitis
Post-ERCP pancreatitis is a well-known and sometimes life-threatening complication of ERCP. Both LR and rectal indomethacin have shown benefit in preventing post-ERCP pancreatitis.
- Trial name
- IND+LRPEP (NCT02641561)
- Testing
- Indomethacin, Lactated Ringer's Solution, Normal Saline
- Where
- United States
- Volunteers
- 192 people, healthy volunteers welcome
- Sponsor
- The Cooper Health System
Endoscopic Retrograde Cholangiopancreatography
Optimal Timing of Double-Wire Technique For Biliary Cannulation at ERCP
The purpose of this study is to give doctors who perform Endoscopic Retrograde Cholangiopancreatography (ERCP) procedures a better idea as to the best techniques to use in order to examine the bile duct as quickly and safely as…
- Trial name
- NCT02297750
- Testing
- double-wire technique in patients undergoing ERCP with biliary cannulation, single-wire technique in patients undergoing ERCP with biliary cannulation
- Where
- United States
- Volunteers
- 161 people
- Sponsor
- Duke University
Biliary Cannulation, Endoscopic Retrograde Cholangiopancreatography
Difficult Cannulation Criteria in Trainee Involved ERCP Cannulation
Endoscopic Retrograde Cholangiopancreatography (ERCP) is one of the most technically challenging procedures in gastrointestinal endoscopy. Selective deep cannulation is a critical step for the performance of ERCP.
- Trial name
- NCT04609917
- Testing
- trainee invlovement
- Where
- China
- Volunteers
- 4,415 people
- Sponsor
- Air Force Military Medical University, China
Pancreatitis
Randomized Trial of Aggressive Fluid Hydration to Prevent Post ERCP Pancreatitis
1. ERCP is a commonly performed endoscopic procedure used to treat stones and blockages of the bile duct as well as to manage leaks which occurs following laparoscopic gallbladder removal. 2.
- Trial name
- NCT01758549
- Testing
- Aggressive Intravenous Hydration Group, Standard Fluids Arm
- Where
- United States
- Volunteers
- 62 people
- Sponsor
- University of Southern California
Chronic Liver Disease and Cirrhosis, Liver Transplant; Complications
Magnetic Resonance Cholangiopancreatography in Living Liver Donors and Its Relationship With Post Operative Recipient Biliary Complications
Living donor liver transplantation is widely accepted as an life-saving treatment for patients with end-stage liver diseases. Careful donor selection is essential to maximize the success and minimize the risk of postoperative…
- Conditions
- Chronic Liver Disease and Cirrhosis, Liver Transplant; Complications, Donor Hepatectomy
- Trial name
- NCT07715500
- Testing
- Magnetic Resonance Cholangiopancreatography
- Where
- India
- Volunteers
- 100 people
- Sponsor
- Institute of Liver and Biliary Sciences, India
Choledocholithiasis With Cholecystitis With Obstruction, Choledocholithiasis With Acute and Chronic Cholecystitis
Single Setting ERCP and Laparoscopic Cholecystectomy is a Safe Procedure in Patients With Cholecysto-Choledocholithiasis
The ideal management of cholecysto-choledocholithiasis is an open cholecystectomy (OC) with the common bile duct (CBD) exploration worldwide.
- Conditions
- Choledocholithiasis With Cholecystitis With Obstruction, Choledocholithiasis With Acute and Chronic Cholecystitis, Cholelithiasis With Acute and Chronic Cholecystitis
- Trial name
- NCT04213092
- Testing
- ERCP+LC, OC+CBD
- Volunteers
- 160 people
- Sponsor
- Lumbini Medical College
Sphincterotomy, Endoscopic, Cholangiopancreatography, Endoscopic Retrograde
Laser Lithotripsy for Difficult Large Bile Duct Stones
Very large bile duct stones are difficult to remove. Dilation-assisted stone extraction, also termed small endoscopic sphincterotomy plus endoscopic papillary large balloon dilatation, is safe and effective technique for the…
- Conditions
- Sphincterotomy, Endoscopic, Cholangiopancreatography, Endoscopic Retrograde, Lithotripsy, Laser
- Trial name
- NCT02538731
- Testing
- dilation-assisted stone extraction, Spyglass Guided Laser Lithotrips
- Volunteers
- 150 people
- Sponsor
- Shandong Provincial Hospital
Cholangiopancreatography, Endoscopic Retrograde
Intraductal Secretin Stimulation Test: What Is the Proper Collection Time?
The aim is to evaluate the peak secretory flow rates and bicarbonate concentrations as determined by a 30 minute intraductal secretin stimulation test in patients with a low likelihood of pancreatic pathology and to compare these…
- Trial name
- IDST (NCT03263481)
- Testing
- Intraductal secretin test (IDST)
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Indiana University
Cholangiopancreatography, Endoscopic Retrograde, Endoscopic Ultrasonography
Non-invasive Monitor in Endoscopic Invasive Procedure
Investigators include the patients who need painless invasive endoscopic procedure, investigators collect the demographic data and apply the non-invasive device ICON on participants during the who procedure.
- Trial name
- NCT03292627
- Testing
- Portable Noninvasive Hemodynamic Monitor
- Where
- Taiwan
- Volunteers
- 200 people
- Sponsor
- National Taiwan University Hospital
Choledocholithiasis
CBD Stenting vs Non-Stenting for Choledocholithiasis
The role of prophylactic biliary stenting after complete clearance of common bile duct stones in patients awaiting cholecystectomy remains controversial.
- Trial name
- NCT07331142
- Testing
- Temporary Plastic Biliary Stent Placement, Endoscopic Retrograde Cholangiopancreatography with Stone Clearance
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- National Liver Institute, Egypt
Patient Population Submitted to ERCP
High Flow Nasal Cannula in Patients Undergoing Endoscopic Retrograde Cholangiopancreatography (ERCP) HF-study
The expected results with this study are that high flow devices (LAF) provide adequate respiratory support during the performance of ERCP under deep sedation, reducing episodes of desaturation, hypoventilation and airway…
- Trial name
- HFS (NCT04082208)
- Testing
- High Flow nasal cannula, Low Flow nasal cannula
- Where
- Spain
- Volunteers
- 172 people
- Sponsor
- Hospital Clinic of Barcelona