Clinical trials: Cholecystitis; Gallstone
Cholecystitis, Cholelithiasis
Feasibility and Utility of Artificial Intelligence (AI) / Machine Learning (ML) - Driven Advanced Intraoperative Visualization and Identification of Critical Anatomic Structures and Procedural Phases in Laparoscopic Cholecystectomy
The goal of this study is to evaluate the utility and efficacy of an artificial intelligence (AI) model at identifying structures and phases of surgery compared to traditional white light assessment by trained surgeons.
- Conditions
- Cholecystitis, Cholelithiasis, Biliary Dyskinesia
- Trial name
- NCT05775133
- Testing
- ICG
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Activ Surgical
Postoperative Pain, Acute Cholecystitis
USG-Guided TAPA vs RIFB Block for Postoperative Analgesia in Laparoscopic Cholecystectomy
Laparoscopic cholecystectomy (LC) can cause moderate-to-severe postoperative pain from visceral, referred shoulder, and incisional sources. Multimodal analgesia is recommended, but opioids carry significant side effects.
- Conditions
- Postoperative Pain, Acute Cholecystitis, Cholelithiasis, Postoperative Nausea and Vomiting
- Trial name
- NCT07552701
- Testing
- M-TAPA Group, RIFPB Group
- Where
- Turkey (Türkiye)
- Volunteers
- 81 people
- Sponsor
- Hitit University
Cholecystectomy, Laparoscopic, Cholecystitis
Clipless Versus Conventional Laparoscopic Cholecystectomy Using Harmonic Scalpel
This randomized controlled trial compares the operative outcomes of clipless laparoscopic cholecystectomy using a harmonic scalpel (HS) versus conventional clip-based laparoscopic cholecystectomy (CLC) in patients with gallstone…
- Conditions
- Cholecystectomy, Laparoscopic, Cholecystitis, Gall Stones (& [Calculus - Gall Bladder])
- Trial name
- NCT07473388
- Testing
- Clipless Laparoscopic Cholecystectomy with Harmonic Scalpel, Conventional Laparoscopic Cholecystectomy
- Where
- Pakistan
- Volunteers
- 158 people
- Sponsor
- Services Hospital, Lahore
Biliary Disease, Gallstone; Cholecystitis, Acute
Multicentric Point of Care UltraSound by Surgeons Trial
Acute gallbladder pathology and acute diverticulitis are common conditions met in emergency departments and comprise the bulk of admissions throughout general surgical calls.
- Conditions
- Biliary Disease, Gallstone; Cholecystitis, Acute, Diverticulitis, Colonic, Abscess Pelvic
- Trial name
- POCUSS (NCT02682368)
- Testing
- Point of Care Ultrasound by Surgeons (POCUSS), Radiology report, Surgery-Intra-operative findings
- Where
- 5 sites in Ireland, Italy and 2 more
- Volunteers
- 183 people, healthy volunteers welcome
- Sponsor
- Connolly Hospital Blanchardstown
Cholecystitis, Gallstones
Fluorescence Cholangiography During Cholecystectomy - a RCT
The primary objective is to compare the success rates of intraoperative fluorescent cholangiography using indocyanine green versus conventional X-ray cholangiography for the identification of bile duct anatomy during laparoscopic…
- Trial name
- NCT02344654
- Testing
- Indocyanine green, Near-infrared illumination, Urografin
- Volunteers
- 120 people
- Sponsor
- Hvidovre University Hospital
Cerebral Hypoperfusion, Cerebral Occlusion
Evaluation of Cerebral Blood Flow and Cerebral Oxygenation With Transcranial Doppler and NIRS in Laparoscopic Cholecystectomy Cases
The goal of this clinical trial is to test intracranial blood flow and cerebral oxygenisation changes in patients who have pneumoperitoneum in laparoscopic cholecystectomy procedure.
- Conditions
- Cerebral Hypoperfusion, Cerebral Occlusion, Cholecystitis; Gallstone, Cholecystitis/Cholelithiasis
- Trial name
- NIRS L/C (NCT06036498)
- Testing
- Near Infrared Spectrophotometry Device, Transcranial Doppler Ultrasonography
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Uludag University
Gall Stone, Gallbladder Inflammation
Benchmarks in Elective Laparoscopic Cholecystectomy
The aim of this observational cohort study is to define peri- and postoperative reference values for elective laparoscopic cholecystectomy, using the achievable benchmarks of care methodology (ABC™).
- Conditions
- Gall Stone, Gallbladder Inflammation, Gall Bladder Pain, Gallstone
- Trial name
- NCT06692517
- Testing
- Laparoscopic cholecystectomy
- Volunteers
- 60,000 people
- Sponsor
- Region Östergötland
Cholelithiasis, Cholecystitis
Investigation of the Effects of Aromatherapy Foot Massage on Postoperative Pain, Sleep, and Recovery in Laparoscopic Cholecystectomy
This randomized controlled study aims to evaluate the effects of aromatherapy foot massage on postoperative pain, sleep quality, and recovery in patients undergoing laparoscopic cholecystectomy.
- Conditions
- Cholelithiasis, Cholecystitis, Gallbladder Diseases, Postoperative Pain
- Trial name
- NCT07363668
- Testing
- aromatherapy foot massage
- Where
- Turkey (Türkiye)
- Volunteers
- 103 people
- Sponsor
- Ataturk University
Mirizzi Syndrome, Cholelithiasis
Treatment of Mirizzi Syndrome
Mirizzi syndrome is an infrequent complication of long-standing cholelithiasis. Extrinsic compression of the common hepatic duct is usually caused by an impacted stone in Hartmann's pouch or cystic duct resulting in the…
- Conditions
- Mirizzi Syndrome, Cholelithiasis, Acute Cholecystitis
- Trial name
- NCT04672902
- Testing
- Single-operator cholangioscopy guided electrohydraulic lithotripsy
- Where
- Mexico
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- Tecnologico de Monterrey
Cholecystitis, Cholelithiasis
Use of Robotics for Cholecystectomy; Retrospective Review of Outcomes, Set Up and Learning Curves
Comparing the use of surgical robotics during a Cholecystectomy, comparing different platforms and approaches (multi port verses single port).
- Trial name
- NCT03059745
- Testing
- Cholecystectomy
- Where
- 2 sites in United States
- Volunteers
- 200 people
- Sponsor
- University of California, Davis
Atelectasis, Postoperative, Cholecystitis; Gallstone
Ultrasound for Postop Lung Issues in Low-Flow Anesthesia
Detecting possible atelectasis and other respiratory problems that may develop immediately after extubation via lung ultrasonography can reduce pulmonary complications by performing necessary interventions such as oxygen support…
- Conditions
- Atelectasis, Postoperative, Cholecystitis; Gallstone, Pulmonary Atelectasis
- Trial name
- NCT06824506
- Testing
- No-intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 110 people
- Sponsor
- Ankara Ataturk Sanatorium Training and Research Hospital
Cholelithiasis, Cholecystitis
Efficacy of Proficiency-based Versus Free Laparoscopic Training in Cholecystectomy on a Virtual Reality Simulator
Virtual reality devices are widely accepted tools to familiarize surgical novices with the principles of laparoscopy. Free Virtual reality training will be tested against basic training and efficacy assessed in a randomized…
- Conditions
- Cholelithiasis, Cholecystitis, Cholecystolithiasis
- Trial name
- NCT01615549
- Testing
- Laparsocopic cholecystectomy
- Where
- 2 sites in Switzerland
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Laparoscopic Cholecystectomy
Effectiveness and Safety of LED Light Source System for Endoscope
This trial is designed as a prospective, multi-center, single-blind, parallel, randomized controlled clinical trial. The trial will be carried out in 5 centers, involving 220 subjects as estimated who will be divided into the…
- Trial name
- ENV (NCT04561583)
- Testing
- LED light source system for endoscope, Pinpoint Endoscopic Fluorescence Imaging System
- Where
- 4 sites in China
- Sponsor
- Stryker Orthopaedics
Cholecystitis, Cholelithiasis
Fluorescent Cholangiography vs White Light for Bile Ducts Identification
The Study is designed to compare the effectiveness of Near Infrared Fluorescence Cholangiography (NIFC) to standard white light imaging (WLI) in visualizing and identifying the main biliary and hepatic structures (Cystic Duct…
- Trial name
- NCT02702843
- Testing
- Laparoscopic cholecystectomy with Xenon light, Laparoscopic cholecystectomy (fluorescent cholangiography)
- Where
- 7 sites in United States, Argentina and 3 more
- Volunteers
- 677 people
- Sponsor
- The Cleveland Clinic
Pancreatitis, Cholangitis
preGallstep - A Clinical Pilot Trial
In Denmark, more than 7500 cholecystectomies are performed every year. Common bile duct gallstones (CBDS) are found in 3.4% to 18% of patients undergoing cholecystectomy.
- Conditions
- Pancreatitis, Cholangitis, Cholecystitis; Gallstone, Jaundice, Obstructive
- Trial name
- NCT04801238
- Testing
- LCBDE + LC, ERC + LC
- Where
- Denmark
- Volunteers
- 150 people
- Sponsor
- Lars Tue Sorensen
Cholecystitis, Acute, Common Bile Duct Calculi
Endoscopic Nasogallbladder Drainage Versus Gallbladder Stenting Before Cholecystecomy
Early laparoscopic cholecystectomy is the current standard therapy for acute cholecystitis, but temporary decompression of the gallbladder (GB) through percutaneous or endoscopic route can be required to alleviate inflammatory…
- Trial name
- NCT02394327
- Testing
- 7-Fr Pigtail type naso-cholecystic drainage tube (Liguory nasal biliary drainage set; Wilson-Cook Medical, Salem, NC, USA), 7-Fr double pigtail plastic stent (Zimmon; Wilson-Cook Medical, Salem, NC, USA)
- Where
- South Korea
- Volunteers
- 35 people
- Sponsor
- Ajou University School of Medicine
Biliary Tract Diseases
Cholecystitis in Villavicencio Hospitals
Background: Acute cholecystitis is a frequent cause of visits to the emergency ward. The complications of delays in attention and surgical therapy are substantial and should be considered to prevent them timely.
- Trial name
- NCT06048575
- Testing
- Cholecystectomy
- Where
- Colombia
- Volunteers
- 609 people
- Sponsor
- Hospital Departamental de Villavicencio
Ascites, Blunt Abdominal Trauma
Telesonography Adaptation and Use to Improve the Standard of Patient Care Within a Dominican Community
The role of teleradiology has far reaching implications for the health of remote and underserved populations. The ability to coordinate radiographic evaluation and diagnosis from a distance has the potential to raise the standard…
- Conditions
- Ascites, Blunt Abdominal Trauma, Cholelithiasis, Cholecystitis
- Trial name
- NCT00591968
- Testing
- SonoSite Titan portable ultrasound coupled with email telediagnosis
- Where
- Dominican Republic
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- Edward Via Virginia College of Osteopathic Medicine
Choledocholithiasis With Cholecystitis With Obstruction, Obstructive Jaundice
Feasibility and Safety of Supraglottic Oxygen Delivery Via an Endotracheal Tube for Non-intubated ERCP Anesthesia: A Two-Stage Phase II Clinical Study
Endoscopic retrograde cholangiopancreatography (ERCP) is a technique for evaluating the bile duct, pancreatic duct, and ampulla.
- Conditions
- Choledocholithiasis With Cholecystitis With Obstruction, Obstructive Jaundice, Pancreatitis, Cholelithiasis
- Trial name
- NCT07051980
- Testing
- Supraglottic Oxygen Delivery via an Endotracheal Tube
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Zhejiang University
Cholelithiasis, Cholecystitis
Cholecystectomy First vs Sequential Common Bile Duct Imaging + Cholecystectomy
The purpose of this study is to evaluate if cholecystectomy first (studied group) versus sequential common bile duct imaging/cholecystectomy (control group) result in a decrease of hospital stay, morbidity/mortality and costs in…
- Trial name
- CCK first (NCT01492790)
- Testing
- Emergency cholecystectomy first, Sequential common bile duct imaging/cholecystectomy
- Where
- Switzerland
- Volunteers
- 100 people
- Sponsor
- University Hospital, Geneva