Clinical trials: Cholelithiasis, active
Acute Pancreatitis, Cholelithiasis
Timing of CHolecystectomy In Severe PAncreatitis
The goal of this clinical trial is to compare outcomes for interval or early laparoscopic cholecystectomy in patients with moderately severe and severe pancreatitis.
- Trial name
- CHISPA (NCT06113419)
- Testing
- Laparoscopic cholecystectomy
- Where
- 2 sites in Colombia
- Volunteers
- 134 people
- Sponsor
- Hospital Universitario Mayor Méderi
Cholelithiasis
Electrosurgical Patterns and Learning Curve in Elective Laparoscopic Cholecystectomy
This prospective observational study will examine how electrosurgical activation patterns during elective laparoscopic cholecystectomy are associated with surgeon experience and intraoperative difficulty.
- Trial name
- ELECTRO-LC (NCT07888491)
- Testing
- Elective laparoscopic cholecystectomy
- Where
- Croatia
- Volunteers
- 165 people
- Sponsor
- University Hospital of Split
Intravenous Anesthesia, Cholelithiasis
Time to Loss of Consciousness With Remimazolam Versus Propofol for Anesthetic Induction in Laparoscopic Cholecystectomy
The goal of this clinical trial is to compare two medicines used to induce general anesthesia in adults undergoing elective laparoscopic cholecystectomy.
- Trial name
- REMIPROP-LOC (NCT07717684)
- Testing
- Remimazolam, Propofol
- Where
- Brazil
- Volunteers
- 66 people
- Sponsor
- Universidade Federal de Sergipe
Cholelithiases, Cholecystitis
Ultrasound-Guided Rectus Sheath Block Versus Local Infiltration
Laparoscopic cholecystectomy is associated with significant postoperative pain originating from trocar sites, pneumoperitoneum, and visceral irritation.
- Conditions
- Cholelithiases, Cholecystitis, Postoperative Pain
- Trial name
- NCT07582029
- Testing
- Rectus Sheath Block, Local Anesthetic Infiltration
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Sisli Hamidiye Etfal Training and Research Hospital
Cholelithiasis
Effects of Postoperative Video-assisted Early Mobilization on Recovery Outcomes
This randomized controlled trial aims to evaluate the effects of video-assisted early mobilization education on postoperative recovery in patients undergoing laparoscopic cholecystectomy.
- Trial name
- NCT07512024
- Testing
- Video-Assisted Early Mobilization Training
- Volunteers
- 44 people
- Sponsor
- Muş Alparslan University
Cholelithiasis, Postoperative Nausea and Vomiting
A Randomized Controlled Trial Comparing the Effects of Different Anesthetic Sedatives on PONV in Laparoscopic Cholecystectomy
This study is designed to compare three sedative medications used during general anesthesia for gallbladder removal surgery (laparoscopic cholecystectomy) and their effects on nausea and vomiting after surgery.
- Trial name
- NCT07758803
- Testing
- Propofol, Ciprofol, Remimazolam
- Where
- China
- Volunteers
- 114 people
- Sponsor
- Xi'an Aerospace General Hospital
Postoperative Pain, Cholelithiasis
Effect of Labetalol, Magnesium Sulfate, or Lidocaine on Opioid Consumption During Laparoscopic Cholecystectomy
Laparoscopic cholecystectomy (gallbladder removal) is one of the most common abdominal operations performed worldwide. Despite its minimally invasive approach, up to half of patients experience notable postoperative pain, which…
- Trial name
- NCT07865455
- Testing
- Labetalol, Magnesium Sulfate, Lidocaine
- Volunteers
- 90 people
- Sponsor
- Assiut University
Cholelithiasis, Cholecystitis
STALL vs Sole Local Wound Infiltration in Laparoscopic Cholecystectomy
This trial is a prospective randomized superiority trial comparing sole ropivacaine based local trocar site infiltration to local infiltration combined with laparoscopic ropivacaine TAP block (STALL) in LCC.
- Conditions
- Cholelithiasis, Cholecystitis, Gallbladder Cancer
- Trial name
- STALL (NCT06123117)
- Testing
- single transversus abdominis laparoscopy-guided plane block, local trocar site ropivacaine infiltration
- Where
- Finland
- Volunteers
- 850 people
- Sponsor
- Helsinki University Central Hospital
Postoperative Pain, Acute Pain
Two Bupivacaine Concentrations for Rectus Intercostal Fascial Plane Block After Laparoscopic Cholecystectomy
Pain after laparoscopic cholecystectomy remains clinically relevant, and current recommendations favour multimodal, opioid-sparing analgesia including regional techniques.
- Conditions
- Postoperative Pain, Acute Pain, Cholelithiasis, Anesthesia
- Trial name
- NCT07841951
- Testing
- Bupivacaine 0.25% - rectus intercostal fascial plane block, Bupivacaine 0.125% - rectus intercostal fascial plane block, Bupivacaine 0.25% - port-site infiltration
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Medipol University
Choledocholithiasis With Cholecystitis With Obstruction, Obstructive Jaundice
Supraglottic Oxygenation Via Oral Transtracheal Catheter for Reducing the Incidence of Hypoxemia During ERCP Under Sedation
Endoscopic retrograde cholangiopancreatography (ERCP) is commonly used for the diagnosis and treatment of pancreatobiliary diseases.
- Conditions
- Choledocholithiasis With Cholecystitis With Obstruction, Obstructive Jaundice, Pancreatitis, Cholelithiasis
- Trial name
- NCT07637721
- Testing
- The Supraglottic Oxygenation Via Oral Transtracheal Catheter Group, The Regular Nasal Cannula
- Where
- 3 sites in China
- Volunteers
- 410 people
- Sponsor
- Zhejiang University
Cholecystectomy, Laparoscopic, Choledocholithiasis
ChOlecystectomy aFter successFul Endoscopic Common Bile Duct Stone Extraction in Elderly
The goal of this study is to compare safety and efficacy of laparoscopic cholecystectomy versus wait-and-see policy after endoscopic removal of common bile duct stones in elderly.
- Conditions
- Cholecystectomy, Laparoscopic, Choledocholithiasis, Cholelithiasis
- Trial name
- COFFEE (NCT07001423)
- Testing
- Laparoscopic cholecystectomy
- Where
- 12 sites in Finland
- Volunteers
- 400 people
- Sponsor
- Helsinki University Central Hospital
Cholecystectomy, Laparoscopic, Cholelithiasis
Improvised Endobag vs Direct Gallbladder Extraction in Laparoscopic Cholecystectomy
Eligigble patients will be enrolled after obtaining informed consent. Basic information such as age, gender, body weight, smoking and alcohol history, number of gallstones, and gallbladder characteristics will be recorded.
- Trial name
- NCT07823803
- Testing
- Endobag
- Where
- Pakistan
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Rawal Institute of Health Sciences Islamabad
Cholesterol Cholelithiasis
A Study to Evaluate the Efficacy and Safety of CnU Capsule 750 mg in Patients With Cholesterol Gallstones(GB Stones).
The objective of this clinical trial is to evaluate the efficacy and safety of CnU capsule 750 mg administration in patients with Cholesterol gallstone (radiolucent gallstones)
- Trial name
- NCT07005752
- Where
- 13 sites in South Korea
- Volunteers
- 484 people
- Sponsor
- Myungmoon Pharma. Co. Ltd.
Gallstone Disease, Bariatric Surgery
ABCG8, UGT1A1 and Gallstone Disease After Bariatric Surgery
The goal of this observational genetic case-control study is to learn whether two specific genetic variants in ABCG8 and UGT1A1 are associated with gallstone disease after bariatric surgery.
- Conditions
- Gallstone Disease, Bariatric Surgery, Metabolic Surgery, Cholecystectomy
- Trial name
- NCT07702630
- Testing
- blood sampling
- Volunteers
- 270 people, healthy volunteers welcome
- Sponsor
- Esbjerg Hospital - University Hospital of Southern Denmark
Cholelithiases, Laparoscopic Cholecystectomy
"Comparison of of Volume-Controlled Ventilation and Pressure-Controlled Ventilation Modes in Laparoscopic Cholecystectomy"
This randomized controlled trial compares volume-controlled ventilation (VCV) and pressure-controlled ventilation (PCV) in adult patients undergoing elective laparoscopic cholecystectomy under general anesthesia.
- Conditions
- Cholelithiases, Laparoscopic Cholecystectomy, General Anaesthesia
- Trial name
- VCV VS PCV (NCT07709039)
- Testing
- Volume-Controlled Ventilation, Pressure Controlled Ventilation
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Mehreen Mirza
Cholelithiasis, Postoperative Pain
Rectointercostal Plane Block (RICPB) for Laparoscopic Cholecystectomy
This prospective randomized controlled trial is designed to evaluate the analgesic efficacy of ultrasound-guided rectointercostal plane block (RICPB) in patients undergoing elective laparoscopic cholecystectomy.
- Trial name
- RICPB (NCT07676552)
- Testing
- Rectointercostal Plane Block, Port-Site Local Anesthetic Infiltration
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Koç University
Cholelithiasis (Without Cholecystitis), Cholecystitis, Acute
Comparison of Gallbladder Extraction Via Subxiphoid vs Infraumbilical Port in Laparoscopic Cholecystectomy
Laparoscopic cholecystectomy is the standard surgical treatment for symptomatic gallstone disease due to its advantages in reducing postoperative pain and recovery times.
- Trial name
- NCT07672145
- Testing
- Subxiphoid Gallbladder Retrieval, Infraumbilical Gallbladder Extraction
- Where
- Pakistan
- Volunteers
- 66 people
- Sponsor
- King Edward Medical University
Cholecystectomy, Gallbladder
EUS-Guided Gallbladder Drainage Versus Conservative Management in Patients Unfit for Surgery After a Biliary Event Without Cholecystitis. DRECON Study
Cholecystectomy is considered the standard definitive treatment after an acute biliary event (biliary colic, acute pancreatitis, cholangitis, or choledocholithiasis).
- Conditions
- Cholecystectomy, Gallbladder, Endoscopic Ultrasound (EUS), Cholelithiasis
- Trial name
- DRECON (NCT07655778)
- Testing
- EUS-guided gallbladder drainage (EUS-GBD), Conservative management (CM)
- Volunteers
- 110 people
- Sponsor
- Hospital Mutua de Terrassa
Cholelithiasis, Postoperative Pain, Laparoscopic Cholecystectomy
ESP vs Subcostal TAP Block for Analgesia After Laparoscopic Cholecystectomy
This prospective, randomized, double-blind study compares the analgesic efficacy of ultrasound-guided erector spinae plane (ESP) block and subcostal transversus abdominis plane (TAP) block in patients undergoing laparoscopic…
- Trial name
- ESP TAP (NCT07661693)
- Testing
- Erector Spinae Plane Block, Subcostal Transversus Abdominis Plane Block
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Gaziantep City Hospital
Gallbladder Diseases, Cholecystitis, Acute
Endoscopic vs Non-endoscopic Drainage for Benign Gallbladder Diseases in High-risk Patients or Patients Desiring Gallbladder Preservation
Common gallbladder conditions like gallstones, polyps, and gallbladder inflammation are typically treated by surgically removing the gallbladder.
- Conditions
- Gallbladder Diseases, Cholecystitis, Acute, Cholelithiasis
- Trial name
- GB-PRESERVE (NCT07649811)
- Testing
- Endoscopic Gallbladder Drainage, Percutaneous Gallbladder Drainage
- Where
- China
- Volunteers
- 220 people
- Sponsor
- Air Force Military Medical University, China