Clinical trials: Cholesterol; Metabolic Disorder
Fed
Bioequivalence Study of Risperidone Tablet 1 mg Under Fed Condition
This is a randomized, open Label, balanced, two-treatment, two-period, two-sequence, single dose, crossover pivotal study. The purpose of this study is to assess the bioequivalence between Test Product and the corresponding…
- Trial name
- NCT01618760
- Testing
- Risperidone Tablet 1 mg, Risperidone
- Where
- India
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- IPCA Laboratories Ltd.
Hyperlipidemias
A Study To Evaluate The Safety And Efficacy Of Atorvastatin In Patients With Diabetes And High Cholesterol
The purpose of this study is to evaluate the efficacy and safety of atorvastatin for the treatment of Taiwanese patients with diabetes and high cholesterol.
- Trial name
- NCT00645424
- Testing
- atorvastatin
- Where
- 5 sites in Taiwan
- Volunteers
- 155 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Hypercholesterolemia
Effectiveness of Treatment of Hypercholesterolemia With Rosuvastatin and Ezetimibe
The aim of the study is to demonstrate, whether the time of day of administration of the study drug (containing rosuvastatin and ezetimibe) has an impact on the effectiveness of lipid-lowering therapy.
- Trial name
- ROSEZE (NCT02772640)
- Testing
- Rosuvastatin and Ezetimibe morning or evening administration
- Where
- Poland
- Volunteers
- 83 people
- Sponsor
- Collegium Medicum w Bydgoszczy
Mets, Death
Association of Egg and Dietary Cholesterol Consumption With Mortality and Diseases
To assess the associations between egg and dietary cholesterol consumption with mortality and metabolic syndrome (MetS).
- Trial name
- NCT04104308
- Volunteers
- 33,453 people
- Sponsor
- Zhejiang University
Obesity
Effect of Different Fiber Breakfasts on Appetite and Weight Change in Overweight Subjects
Regular breakfast consumption may help lower body weight reduce body fatness and improve cardiovascular disease risk factors. However, the best kind of breakfast to consume to achieve these effects is unclear.
- Trial name
- NCT02035150
- Testing
- Oatmeal, Frosted Flakes, No Breakfast
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- New York Obesity and Nutrition Research Center
Insulinemic Response, Type 2 Diabetes (Adult Onset)
Impact of High-Oleic Palm Oil Consumption on Cardiovascular Biomarkers in Adults in Bogotá
This randomized clinical trial aims to evaluate the effects of refined high-oleic palm oil consumption on cardiovascular risk biomarkers and insulin resistance in healthy adults.
- Conditions
- Insulinemic Response, Type 2 Diabetes (Adult Onset), Hyperglycaemia (Diabetic), Hyperlipidaemia
- Trial name
- EDCHOPA-CRB (NCT07748559)
- Testing
- High-oleic palm oil
- Where
- Colombia
- Volunteers
- 52 people
- Sponsor
- Ruby Alejandra Villamil
Chronic Kidney Disease
Triglyceride/High-density Lipoprotein Cholesterol Ratio in Chronic Kidney Disease
The Triglycerides (TG) to High Density Lipoprotein Cholesterol (HDL-C) ratio is a feature of insulin resistance and an independent predictor of cardiovascular risk.
- Trial name
- NCT02113462
- Where
- Turkey (Türkiye)
- Volunteers
- 197 people
- Sponsor
- Gulhane School of Medicine
Cardiovascular Diseases, Heart Diseases
Evaluation of Cholesterol Education for At-Risk Children
To evaluate two educational programs that promoted the role of pediatric practices in lowering LDL cholesterol levels in 4-10 year old hypercholesterolemic children through dietary modification.
- Conditions
- Cardiovascular Diseases, Heart Diseases, Hypercholesterolemia, Coronary Heart Disease Risk Reduction
- Trial name
- NCT00005718
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Hypercholesterolemia, Coronary Heart Disease
Evaluation of the Efficacy of Rosuvastatin in Daily Practice (TARGET)
In this study the effect of the switch to rosuvastatin from another statin (fluvastatin, pravastatin, simvastatin, atorvastatin) was evaluated in high-risk patients with and without evident CHD and LDL-C ≥ 3.2 mmol/l.
- Trial name
- NCT00396110
- Volunteers
- 3,889 people
- Sponsor
- AstraZeneca
Hypercholesterolaemia
Non-interventional Study (NIS) to Assess Reaching of Cholesterol Target Values in Patients Treated With HMG-CoA Reductase Inhibitors
This is a multi-centre non-interventional study of patients who are treated with any HMGCoA reductase inhibitor available in Croatia (rosuvastatin, simvastatin, atorvastatin and fluvastatin) for at least 6 months.
- Trial name
- NCT01257971
- Where
- 27 sites in Croatia
- Volunteers
- 1,868 people
- Sponsor
- AstraZeneca
Diabetes
Effects of Rosuvastatin on the, in Vivo, Kinetic of apoB and apoA1, Using Stable Isotopes, in Type 2 Diabetic Patients
Statins have been shown to reduce significantly the risk for cardiovascular events in patients with type 2 diabetes and statin therapy is largely recommended in this high cardiovascular risk population.
- Trial name
- NCT00658463
- Testing
- Rosuvastatin
- Where
- France
- Volunteers
- 8 people
- Sponsor
- Centre Hospitalier Universitaire Dijon
Coronary Disease
Atherosclerosis in the Coronary and Carotid Arteries
This study will compare changes in atherosclerotic plaque in the coronary arteries (vessels on the surface of the heart that supply blood to the heart) with changes in the carotid arteries (vessels in the neck that supply blood…
- Trial name
- NCT00080587
- Where
- United States
- Volunteers
- 125 people
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Obesity, Visceral Adipose Tissue
Nutritional Oleic Acid Modulation of adIpose Cholesterol Metabolism in Patients Living With Obesity
Disruption of white adipose tissue (WAT) homeostasis during obesity is central to the development of associated cardiometabolic complications.
- Conditions
- Obesity, Visceral Adipose Tissue, White Adipose Tissue Inflammation, Subcutaneous Adipose Tissue
- Trial name
- NAMICO (NCT07027033)
- Testing
- acid-rich sunflower oil oleic acid, conventional sunflower oil
- Where
- France
- Volunteers
- 40 people
- Sponsor
- Nantes University Hospital
Type 2 Diabetes, Hypercholesterolemia
The Potential Effects and Mechanisms of Flax Lignans on Type 2 Diabetes Mellitus
The purpose of the study is to improving the lipid profile and glucose control in type 2 diabetic patients with supplementation of flax lignans.
- Trial name
- NCT00363233
- Testing
- flax lignans
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Chinese Academy of Sciences
Hypercholesterolemia
Study to Evaluate the Cholesterol Lowering Effects of Two Marketed Drugs in Patients With Elevated Cholesterol Levels (0653A-058)
A 10-week study to compare the reduction in cholesterol following treatment with two different marketed drugs in patients with hypercholesterolemia.
- Trial name
- NCT00090298
- Testing
- MK0653A, ezetimibe (+) simvastatin, Comparator: Rosuvastatin
- Volunteers
- 2,815 people
- Sponsor
- Organon and Co
Healthy
Bioavailability Study of Ondansetron Orally Disintegrating Tablets Under Fed Conditions
To compare the single-dose bioavailability of Ondansetron ODT 8 mg and Zofran 8 mg
- Trial name
- NCT00653458
- Testing
- Ondansetron, Zofran
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Par Pharmaceutical, Inc.
Primary Hypercholesterolemia, Dyslipidemia
Study to Compare the Efficacy of Pitavastatin With That of Atorvastatin in Lowering Cholesterol Levels
The purpose of this study is to compare the efficacy of pitavastatin with that of atorvastatin.
- Trial name
- NCT00249249
- Testing
- Pitavastatin, Atorvastatin
- Where
- 192 sites in Denmark, Finland and 11 more
- Volunteers
- 830 people
- Sponsor
- Kowa Research Europe
Blood Clots, Infection and Inflammatory Reaction
Cobas® Lumira Collection of Venous and Capillary Blood Samples for the Research, Optimization and Calibration of New Diagnostic Devices
This study is a blood sample collection study, collecting venous and capillary blood samples from adult patients in the UK, with a range of health conditions.
- Conditions
- Blood Clots, Infection and Inflammatory Reaction, Heart Disease, Kidney Disease
- Trial name
- EVOLVE (NCT07378514)
- Testing
- Blood samples are obtained and pseudonymized, prior to use for the development, optimization and calibration of diagnostic tests
- Volunteers
- 30,000 people
- Sponsor
- LumiraDx UK Limited
Hypercholesterolemia, Cardiovascular Risk
Long-Term Cardiovascular Impact of ArmoLIPID Cholesterol Plus: An In Silico Study Using Digital Twins
The goal of this study, conducted entirely using computer simulations, is to evaluate the projected long-term cardiovascular impact of the new ArmoLIPID Cholesterol Plus formulation in adults with mild-to-moderate…
- Trial name
- ARMOLIPID-DT (NCT07892092)
- Where
- Spain
- Volunteers
- 100,000 people
- Sponsor
- Aeterna Medical Solutions SL
Laparoscopic Sleeve Gastrectomy, Cardiovascular Risk Factor
Impact of Sleeve Gastrectomy on Monocyte-to-High-Density Lipoprotein Cholesterol Ratio
The present study hypothesized that significant weight loss is associated with a reduction in the inflammatory markers, leading to diminished cardiovascular risks in patients undergoing laparoscopic sleeve gastrectomy (LGS).
- Conditions
- Laparoscopic Sleeve Gastrectomy, Cardiovascular Risk Factor, Obesity
- Trial name
- NCT04439851
- Volunteers
- 125 people
- Sponsor
- Umraniye Education and Research Hospital
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