Clinical trials: Chronic; Gastritis, Atrophic
Chronic Atrophic Gastritis, Gastric Carcinoma
Curcumin in Preventing Gastric Cancer in Patients With Chronic Atrophic Gastritis or Gastric Intestinal Metaplasia
This randomized phase IIb trial studies how well curcumin works in preventing gastric cancer in patients with chronic atrophic gastritis and/or gastric intestinal metaplasia.
- Trial name
- NCT02782949
- Testing
- Curcumin, Laboratory Biomarker Analysis, Quality-of-Life Assessment
- Where
- 2 sites in Honduras, Puerto Rico
- Volunteers
- 50 people
- Sponsor
- National Cancer Institute (NCI)
Colorectal Cancer, Colorectal Adenoma
Volatile Markers in Digestive Cancer
The study is aimed to determine the potential of volatile marker testing for identification of gastrointestinal cancers (in particular - colorectal and gastric cancers), the related precancerous lesions in the stomach and colon.
- Conditions
- Colorectal Cancer, Colorectal Adenoma, Gastric Cancer, Peptic Ulcer Disease
- Trial name
- VOLGACORE (NCT02332213)
- Testing
- Breath sampling for volatile marker detection, Upper endoscopy with biopsies, Colonoscopy with biopsies or lesion removal when required
- Where
- 2 sites in Latvia, Lithuania
- Volunteers
- 2,022 people, healthy volunteers welcome
- Sponsor
- University of Latvia
Chronic Erosive Gastritis
A Study to Evaluate the Efficacy of Teprenone On Chinese Patients With Chronic Non-Atrophic Erosive Gastritis
The purpose of this study is to evaluate the efficacy of teprenone on chronic non-atrophic erosive gastritis and its therapeutic mechanism
- Trial name
- NCT01284647
- Where
- 8 sites in China
- Volunteers
- 156 people
- Sponsor
- Changhai Hospital
Chronic Atrophic Gastritis
Clinical Study of Umbilical Cord Blood Mononuclear Cell Therapy for the Treatment of Chronic Atrophic Gastritis
To evaluate the efficacy and safety of umbilical cord blood mononuclear cells in the treatment of chronic atrophic gastritis.
- Trial name
- NCT05808010
- Testing
- Mononuclear cells, Weifuchun+Hydrotalcite/L-Glutamine and Sodium Gualenate Granules
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Shandong Provincial Hospital
Gastritis, Atrophic, Stomach Neoplasms
Gastropanel for Gastric Atrophy and Cancer Risk Assessment
Background: Atrophic gastritis (AG) is the single most important precursor condition for gastric cancer (GC) known so far. H. pylori infection is the most important causative agent of gastritis, and subsequent AG.
- Trial name
- NCT02114411
- Testing
- GastroPanel test, Gastroscopy
- Where
- United Kingdom
- Volunteers
- 250 people
- Sponsor
- Biohit Healthcare Ltd
Gastritis
Study of the Chinese Prescription Weiqi Decoction on Chronic Atrophic Gastritis
The purpose of this study is to evaluate the efficacy and safety of the Chinese prescription Weiqi decoction on Chronic Atrophic Gastritis.
- Trial name
- NCT00920712
- Testing
- Weiqi decotion
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Shanghai University of Traditional Chinese Medicine
Neoplasm, Stomach, H. Pylori Infection
Early Detection and Screening Strategy of Gatric Cancer in Sichuan Province-A Prospective Cohort Study (WCH-GC-SIGES-01)
To establish prospective cohort of healthy population and corresponding serum sample bank in Sichuan province to provide platform for exploring early diagnosis and screening strategy of gastric cancer by a prospective cohort…
- Conditions
- Neoplasm, Stomach, H. Pylori Infection, Chronic Atrophic Gastritis
- Trial name
- SIGES-01 (NCT03597672)
- Where
- China
- Volunteers
- 30,000 people, healthy volunteers welcome
- Sponsor
- Jian-Kun Hu
Gastric Cancer, Atrophic Gastritis
Screening of Gastric Cancer Via Breath Volatile Organic Compounds by Hybrid Sensing Approach
The study is aimed to determine the potential of volatile marker testing for gastric cancer screening. The study will be addressing the role of confounding factors, including lifestyle factors, diet, smoking as well as addressing…
- Conditions
- Gastric Cancer, Atrophic Gastritis, Gastric Dysplasia, H.Pylori Infection
- Trial name
- VOGAS (NCT04022109)
- Testing
- Breath sampling for VOC detection, Surgery material collection for VOC headspace analysis, Upper endoscopy
- Where
- 5 sites in Brazil, Chile and 3 more
- Volunteers
- 5,000 people
- Sponsor
- University of Latvia
Gastritis
Efficacy and Safety of Houtou Jianweiling Tablet in the Treatment of Chronic Non-Atrophic Gastritis
To study the efficacy \& safety of Houtou Jianweiling tablet through the non-inferiority clinical trial of Houtou Jianweiling tablet with Omeprazole Enteric-coated tablet in patients with chronic non-atrophic gastritis.
- Trial name
- CT (NCT04672018)
- Testing
- Houtou Jianweiling tablet, Omeprazole Tablet
- Where
- Pakistan
- Volunteers
- 240 people
- Sponsor
- University of Karachi
Chronic Atrophic Gastritis
The Study of Chinese Medicine for the Treatment of Chronic Atrophic Gastritis
The purpose of this study is to evaluate efficacy of Chinese medicine treatment for chronic atrophic gastritis. It is a multi-center, randomized, placebo-controlled trial.
- Trial name
- NCT02955134
- Testing
- Talcid®, Chinese medicine prescription, Compound Azimtamide Entieric-coated Tablets
- Where
- 13 sites in China
- Volunteers
- 468 people
- Sponsor
- Wangjing Hospital, China Academy of Chinese Medical Sciences
Helicobacter Pylori, Atrophic Gastritis
Helicobacter Pylori, Atrophic Gastritis and Intestinal Metaplasia Registry and Prospective Study
Since much is unknown about factors that lead to progression of the pre-neoplastic lesions and cancer. In addition, there is ongoing debate on the optimal surveillance intervals and techniques.
- Conditions
- Helicobacter Pylori, Atrophic Gastritis, Intestinal Metaplasia
- Trial name
- NCT05053945
- Testing
- Esophagogastroduodenoscopy
- Where
- 2 sites in Hong Kong
- Volunteers
- 260 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Chronic Atrophic Gastritis
Evaluation of the Efficacy of Electroacupuncture in the Treatment of Chronic Atrophic Gastritis
Brief Summary Template for the Study: This clinical trial aims to evaluate whether electroacupuncture can treat chronic atrophic gastritis (CAG) in adult subjects aged 18 to 75 years (including both males and females), all of…
- Trial name
- NCT07152860
- Testing
- 5 Hz electroacupuncture combined tipronone capsules, Simple tipronone capsules group(The basic treatment group)
- Where
- 3 sites in China
- Volunteers
- 100 people
- Sponsor
- Yi Liang
Atrophic Gastritis
Usefulness of Serum Pepsinogen and Gastrin as the Predictive Biomarker of Atrophic Gastritis, Intestinal Metaplasia and Gastric Cancer in Korea
It is well-known that atrophic gastritis is a major risk factor for gastric cancer, which leads to variations in the serum levels of gastrin, pepsinogen (PG) I, and PGII.
- Trial name
- NCT02184910
- Testing
- pepsinogen and gastrin
- Where
- South Korea
- Volunteers
- 108 people
- Sponsor
- Yonsei University
Chronic Atrophic Gastritis
Objective Study on Tongue Diagnosis of Chronic Atrophic Gastritis
Chronic atrophic gastritis with intestinal metaplasia or dysplasia is called precancerous lesions of gastric cancer ( PLGC ). It is an important stage in the transformation of normal mucosa to gastric cancer and is significantly…
- Trial name
- NCT06489132
- Volunteers
- 498 people, healthy volunteers welcome
- Sponsor
- Peking University First Hospital
Helicobacter Pylori, Early Gastric Cancer
Distribution Characteristics of Helicobacter Pylori
This study aimed to analyze the distribution characteristics of Helicobacter pylori（H. pylori） in varying stages of atrophic gastritis and early gastric cancer using immunohistochemical staining, with the goal of providing…
- Trial name
- NCT07253948
- Testing
- immunohistochemical testing
- Where
- China
- Volunteers
- 231 people
- Sponsor
- Jilin University
Gastric Cancer, Intestinal Metaplasia of Gastric Mucosa
The GAstric Precancerous Conditions Study
Gastric cancer afflicts 27,000 Americans annually and carries a dismal prognosis. One reason for poor outcomes is late diagnosis, as the majority of gastric cancers in the United States are diagnosed at a relatively advanced…
- Conditions
- Gastric Cancer, Intestinal Metaplasia of Gastric Mucosa, Helicobacter Pylori Infection, Atrophic Gastritis
- Trial name
- GAPS (NCT04191551)
- Where
- United States
- Volunteers
- 600 people
- Sponsor
- Stanford University
Tuberculosis, Gastric Cancer
Volatiles in Breath and Headspace Analysis - Diagnostic Markers
Detection of Volatile Organic Compounds (VOC) directly from tissue by headspace analysis (skin, surgery material, other tissue) and exhaled breath is feasible using affordable user-friendly novel nano-chemo sensors that can…
- Conditions
- Tuberculosis, Gastric Cancer, Peptic Ulcer, Atrophic Gastritis
- Trial name
- Volatolome (NCT03228095)
- Testing
- VOC detection in breath and in skin headspace, Breath sampling, Upper endoscopy with biopsies
- Where
- Latvia
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- University of Latvia
Atrophic Gastritis
Atrophic Gastritis Predicts the Risk of Gastric Cancer
Despite declining incidence rates, gastric cancer (GC) ranks the fourth leading cause of cancer-related mortality and the fifth most common cancer worldwide, with the highest incidence reported in Eastern Asia.
- Trial name
- NCT06203327
- Testing
- Esophagogastroscopy (OLGA 0-Ⅰ), Esophagogastroscopy (OLGA II), Esophagogastroscopy (OLGA III-IV)
- Where
- China
- Volunteers
- 2,042 people
- Sponsor
- Shanghai Jiao Tong University School of Medicine
Gastric Cancer, Intestinal Metaplasia
Prediction of Gastric Cancer in Intestinal Metaplasia and Atrophic Gastritis
The primary objectives of this study are: To identify clinical or histological factors associated with gastric cancer development in patients with IM and AG To establish a machine learning algorithm for prediction of future…
- Conditions
- Gastric Cancer, Intestinal Metaplasia, Atrophic Gastritis
- Trial name
- GIMA (NCT04840056)
- Where
- Hong Kong
- Volunteers
- 1,300 people
- Sponsor
- Chinese University of Hong Kong
Atrophic Gastritis
Grading Atrophic Gastritis by Confocal Laser Endomicroscopy Probe (p-CLE)
Atrophic gastritis (AG) is a chronic disease, associated to gastric adenocarcinoma moreover if severity AG is present. Sydney system classified AG as mild, moderate and severe, but with moderate interobserver agreement, due to…
- Trial name
- NCT02351154
- Testing
- Cellvizio Viewer software
- Where
- Ecuador
- Volunteers
- 30 people
- Sponsor
- Instituto Ecuatoriano de Enfermedades Digestivas