Clinical trials: Chronic Aphasia
Aphasia, Cerebrovascular Accident
Role of the Right Brain in Recovery of Language Function in Chronic Stroke
This study will examine in healthy individuals and in patients with aphasia (a language disturbance that is usually caused by stroke, brain disease, or injury) which parts of the brain are involved in naming everyday objects.
- Trial name
- NCT00076479
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Chronic Aphasia
Targeted Electrotherapy for Aphasia Stroke Rehabilitation (TEASER) - Phase II Multi-Center Study
This Phase II study aims to ascertain the effectiveness of HD-tDCS for adjunctive treatment of anomia in chronic aphasia post stroke.
- Trial name
- NCT02540109
- Testing
- HD-tDCS (Soterix Medical, Active)
- Where
- 2 sites in United States
- Volunteers
- 58 people
- Sponsor
- Soterix Medical
Aphasia, Stroke
Memantine and Constraint-Induced Language Therapy in Chronic Poststroke Aphasia:A Randomized Controlled Trial
Aphasia, the loss or impairment of language caused by brain damage, is one of the most devastating cognitive impairments of stroke. Aphasia can be treated with combination of speech-language therapy and drugs.
- Trial name
- NCT00196703
- Testing
- memantine, constraint-induced language therapy
- Where
- Spain
- Volunteers
- 30 people
- Sponsor
- Gabinete Berthier y Martínez
Stroke, Aphasia
Effects of Transcranial Direct Current Stimulation (tDCS) on Language
This study will investigate the effects of mild electrical stimulation in conjunction with speech therapy for people with post-stroke aphasia to enhance language recovery.
- Trial name
- NCT04166513
- Testing
- Targeted Transcranial Direct Current Stimulation, Active Control Transcranial Direct Current Stimulation, Phonologic-Focused Speech Therapy
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Medical College of Wisconsin
Aphasia
Effect of Community Choir Singing in People With Chronic Post-stroke Aphasia
The goal of this randomized controled trial is to test the effects of assigning people with chronic post-stroke aphasia to 12 weekly choir sessions, compared to usual care.
- Trial name
- NCT06368323
- Testing
- Choir singing, Usual care
- Where
- 4 sites in United States, Canada
- Volunteers
- 50 people
- Sponsor
- University of Ottawa
Stroke
Dextroamphetamine and tDCS to Improve the Fluency
The proposed study aims to evaluate safety and efficacy of combined dextroamphetamine (Dexedrine) and transcranial direct current stimulation (tDCS) with melodic intonation therapy (MIT) for treatment of aphasia after stroke.
- Trial name
- NCT02514044
- Testing
- Dexedrine, Active tDCS, Speech Therapy
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- The University of Texas Health Science Center, Houston
Anomia, Post-stroke Aphasia
Executive Training and Anomia Therapy in Chronic Post-stroke Aphasia
Aphasia is a devastating acquired language impairment mainly caused by stroke, in which anomia is a quintessential clinical feature.
- Trial name
- ETAT PSA (NCT05101408)
- Where
- France
- Volunteers
- 10 people
- Sponsor
- University Hospital, Montpellier
Aphasia, Stroke
Effects of Recursive Self-feedback on Speech Production in Aphasia
The goal of this clinical trial is to test the effects of recursive self-feedback procedures on spontaneous speech production in stroke survivors with impaired speech production (aphasia).
- Trial name
- NCT06323629
- Testing
- Adaptive recursive self-feedback procedure, Non-adaptive recursive self-feedback procedure
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- University of South Florida
Aphasia, Stroke
Tablet-based Aphasia Therapy in the Chronic Phase
Aphasia is one of the most common and disabling disorders following stroke, in many cases resolving in long-term deficits. There is evidence that intensive aphasia therapy is effective for language recovery, even in the chronic…
- Trial name
- NCT03622411
- Testing
- speech app, brain games, aphasia therapy
- Where
- Belgium
- Volunteers
- 15 people
- Sponsor
- University Hospital, Ghent
Aphasia, Post-stroke
Transcranial Direct Current Stimulation to Enhance Training Effectiveness in Chronic Post-Stroke Aphasia
The aim of the study is to investigate whether intensive speech-language therapy (SLT) combined with anodal transcranial direct current stimulation (tDCS) leads to better communication performance than SLT combined with placebo…
- Trial name
- NCT03930121
- Testing
- Anodal transcranial direct current stimulation (tDCS) combined with speech-language therapy (SLT, including naming therapy and communicative-pragmatic therapy)
- Where
- 19 sites in Germany
- Volunteers
- 130 people
- Sponsor
- University Medicine Greifswald
Aphasia, Acquired, Speech Therapy
Anomia Therapy and Executive Function Training in Chronic Post-stroke Aphasia: Pilot Study of Multidimensional Effects
The goal of this clinical trial is to measure the effects of a speech therapy protocol combining anomia therapy and executive function training on naming and discourse in people with chronic aphasia, and to study the related…
- Trial name
- ATAC2PILOT (NCT06712225)
- Testing
- Anomia therapy: semantic feature analysis and phonological components analysis;, Executive function training: computerized equipment
- Volunteers
- 8 people
- Sponsor
- University Hospital, Montpellier
Stroke
Cerebellar Transcranial Direct Current Stimulation and Aphasia Treatment
People with post-stroke aphasia are left with some degree of chronic deficit for which current rehabilitative treatments are variably effective.
- Trial name
- NCT02901574
- Testing
- Anodal or Cathodal tDCS, Computerized naming therapy
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Johns Hopkins University