Clinical trials: Chronic Arthritis
Osteoarthritis, Knee, Osteoarthritis, Hip
Helping Osteoarthritis Patients to Walk With NSAID
There is a lack of effective analgesic treatments to help walking patients with painful hip/knee osteoarthritis. Our team therefore imagined a new strategy lying on a multimodal rehabilitation walking program with the help of a…
- Conditions
- Osteoarthritis, Knee, Osteoarthritis, Hip, Chronic Pain
- Trial name
- PERIPATEI (NCT05761015)
- Testing
- therapeutic program including intermittent drug intake and multimodal rehabilitation program
- Where
- France
- Volunteers
- 55 people
- Sponsor
- University Hospital, Clermont-Ferrand
Hip Dysplasia, Hip Pain Chronic
Psychosocial Interventions for Young Adults With Hip Pain
Psychosocial conditions are common in young adults with hip pain including depression, anxiety, pain catastrophizing, and narcotic use. The incidence of these conditions is not well defined.
- Conditions
- Hip Dysplasia, Hip Pain Chronic, Hip Osteoarthritis, Hip Arthritis
- Trial name
- NCT04039386
- Testing
- Cell Phone Based Cognitive Based Therapy (Pacifica App), Control
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Michael C Willey
Rheumatoid Arthritis (RA, Ankylosing Spondylitis
Skin Autofluorescence Assessment of Advanced Glycation End Products in Rheumatic Diseases
Rheumatic diseases are chronic inflammatory conditions that can lead to long-term tissue damage and increased cardiovascular and metabolic risk.
- Conditions
- Rheumatoid Arthritis (RA, Ankylosing Spondylitis, Psoriatic Arthritis, Reactive Arthritis (ReA)
- Trial name
- NCT07329556
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Bursa City Hospital
Spondyloarthritis, Rheumatoid Arthritis
SarS-Cov-2 Viral Infection (COVID-19) in Patients With Chronic Inflammatory Rheumatism
The purpose of this study is to assess whether immunosuppressive therapies used by patients with chronic inflammatory rheumatic diseases have an impact on the viral load and the humoral and cellular responses during viral…
- Conditions
- Spondyloarthritis, Rheumatoid Arthritis, Covid19
- Trial name
- COVIRIC (NCT04584541)
- Testing
- blood tests, Nasopharyngeal swabs, Stools
- Where
- France
- Volunteers
- 150 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Pain, Knee Osteoarthritis
A Study to Evaluate the Efficacy and Safety of CG5503 Prolonged Release (PR) in Subjects With Moderate to Severe Chronic Pain Due to Osteoarthritis of the Knee
The purpose of this study is to evaluate whether tapentadol (CG5503) prolonged-release (PR) tablets at doses of 100-250 mg twice daily provide a better pain relief in patients with moderate to severe chronic pain due to…
- Trial name
- NCT00486811
- Testing
- Tapentadol ER (100 to 250 mg twice daily), Oxycodone CR (20 to 50 mg twice daily)
- Where
- 100 sites in Austria, Croatia and 11 more
- Volunteers
- 990 people
- Sponsor
- Grünenthal GmbH
Rheumatoid Arthritis, Spondyloarthritis
Predicting Hospitalized Infection in Patients With Chronic Inflammatory Arthritis Treated With Biological Drugs
Background The risk for hospitalized infection (i.e. infection leading to hospitalization) in patients with inflammatory arthritis (rheumatoid arthritis (RA), psoriatic arthritis (PsA) or axial spondyloarthritis (axSpA) treated…
- Conditions
- Rheumatoid Arthritis, Spondyloarthritis, Psoriatic Arthritis
- Trial name
- NCT03496831
- Testing
- Biologic Agents
- Volunteers
- 7,500 people
- Sponsor
- Simon Krabbe
Hip Osteoarthritis, Hip Pain Chronic
Continuous Radiofrequency in Hip Osteoarthritis Pain: A Randomized Clinical Trial.
This will be a prospective, single-center, double-blinded, randomized study designed to compare the efficacy of the intraarticular injection of a corticosteroid and the Conventional Radiofrequency (CRF) of the anterior sensory…
- Trial name
- NCT06221709
- Testing
- Conventional Radiofrequency (CRF group), Intraarticular Infiltration ( Control group)
- Where
- Brazil
- Volunteers
- 70 people
- Sponsor
- University of Brasilia
Knee Osteoarthritis, Joint Pain
Femoral Rotation and Patellar Positioning After TKA
Analysis of patellar positioning in the trochlear groove after TKA with and without the use of dynamic tensioner.
- Conditions
- Knee Osteoarthritis, Joint Pain, Joint Instability, Patella Disorder
- Trial name
- NCT05871112
- Testing
- Use of dynamic tensioner
- Where
- Poland
- Volunteers
- 125 people
- Sponsor
- Medical University of Warsaw
Fatigue Syndrome, Chronic, Fibromyalgia
Pain Inhibition in Patients With Rheumatoid Arthritis and Central Sensitivity Syndromes
Both patients with peripheral structural pathologies, like rheumatoid arthritis (RA)-patients, or patients with central sensitivity syndromes (CSS) suffer chronic pain.
- Conditions
- Fatigue Syndrome, Chronic, Fibromyalgia, Arthritis, Rheumatoid
- Trial name
- NCT01154647
- Testing
- citalopram, 1 ml 0.9 % NaCl
- Where
- Belgium
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Vrije Universiteit Brussel
Knee Osteoarthritis, Pain, Chronic
Association of Acupuncture and Cupping in Advanced Knee Osteoarthritis
Given the lack of studies in the literature associating the use of acupuncture and sliding suction cup in patients with advanced knee osteoarthritis, the objective of this study is to evaluate the benefits of this association in…
- Trial name
- NCT04168593
- Testing
- Acupuncture
- Where
- Brazil
- Volunteers
- 120 people
- Sponsor
- University of Sao Paulo General Hospital
Chronic Pain, Osteoarthritis
Predicting Successful Outcome of Interdisciplinary Biopsychosocial Rehabilitation in Osteoarthritis
The goal of this prospective study is to identify variables that can predict whether an interdisciplinary biopsychosocial intervention for patients with osteoarthritis will be successful.
- Conditions
- Chronic Pain, Osteoarthritis, Disability Physical
- Trial name
- CIR-predict (NCT05661760)
- Testing
- interdisciplinary multimodal pain treatment
- Where
- Netherlands
- Volunteers
- 2,309 people
- Sponsor
- Maastricht University
Ankylosing Spondylitis, Rheumatoid Arthritis
Quality of Life in Chronic Arthritis
Chronic joint complaints are prevalent in clinical practice. If chronic arthritis such as rheumatoid arthritis (RA) or ankylosing spondylitis (AS) is not adequately controlled, it can not only affect patient's working ability but…
- Trial name
- NCT01357018
- Where
- Taiwan
- Volunteers
- 139 people
- Sponsor
- Far Eastern Memorial Hospital
Arthritis, Pain
Intra-articularInjection of Botulinum Toxin Type
The purpose of this study is to determine whether intra-articular injection of botulinum toxin is effective in the treatment of chronic knee paindue to arthritis.
- Trial name
- NCT00211679
- Testing
- Botulinum Toxin Type A
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Minneapolis Veterans Affairs Medical Center
Chronic Knee Osteoarthritis
Ultrasound-guided Radiofrequency Ablation of the Genicular Nerve Versus Physical Therapy for Chronic Knee Osteoarthritis
The aim of this study is to compare the effects of conventional physiotherapy methods with ultrasound-guided radiofrequency ablation of the genicular nerve on pain and functional status in patients with stage 2-3 chronic knee…
- Trial name
- NCT06173830
- Testing
- radiofrequency ablation, physical therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 68 people
- Sponsor
- Ankara City Hospital Bilkent
Osteoarthritis, Knee
Predictive Values for the Outcome of Genicular Nerve Radiofrequency Ablation for Chronic Knee Pain
Researchers are trying to assess a predictive value or correlation between patient and procedural characteristics and outcome measures results after genicular nerve radiofrequency ablation.
- Trial name
- NCT05222776
- Where
- Turkey (Türkiye)
- Volunteers
- 206 people
- Sponsor
- Diskapi Teaching and Research Hospital
Peripheral Neuropathies, Osteoarthritis
A Proof of Concept Study to Investigate the Effect of a New Treatment in Patient With Chronic Pain
The purpose of this clinical trial conducted in patients suffering from chronic pain is to study the relationship between individual patients' profile and their analgesic response
- Trial name
- NCT02459197
- Testing
- Heat Pain Stimuli A, Heat Pain Stimuli B, Positive Video
- Where
- 6 sites in Belgium, France
- Volunteers
- 114 people
- Sponsor
- Tools4Patient
Juvenile Idiopathic Arthritis
Sleep Innovations for Preschoolers With Arthritis (SIPA): Developing and Pilot Testing of a Self-Management Intervention
Behavioral sleep problems such as sleep onset delays and frequent night wakings are common among young children (2-5 years). Children with a chronic health condition such as juvenile idiopathic arthritis (JIA) are even more prone…
- Trial name
- NCT04354337
- Testing
- Sleep Innovations for Preschoolers with Arthritis (SIPA)
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- University of Washington
Knee Osteoarthritis, Chronic Pain
Arthritis Ease Study
The goal of this clinical trial is to test using a pain and anxiety reduction phone application in older adults with knee osteoarthritis and chronic pain. The main questions it seeks to answer are: 1.
- Conditions
- Knee Osteoarthritis, Chronic Pain, Kinesiophobia
- Trial name
- NCT05721352
- Testing
- Virtual Reality Nature scene plus heart rate variability biofeedback phone application
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Arizona State University
Peripheral Neuropathy, Osteoarthritis
A Study to Investigate the Genetic Variation of Dopamine Pathway in Patients With Chronic Pain
Patients having completed former trials T1001-01 or T1001-02 will undergo one blood sampling for genotyping purposes. In addition they will compete the personality questionnaires they had completed in the former trial.
- Trial name
- NCT02989792
- Testing
- Blood sampling for genotyping, Personality Questionnaires completion
- Where
- 4 sites in Belgium, France
- Volunteers
- 110 people
- Sponsor
- Tools4Patient
Hip Arthropathy, Hip Osteoarthritis
Erector Spinae vs. PENG Block for Total Hip Arthroplasty
Effect of PENG block and ESPB on pain management, and NLR and PLR following knee arthroplasty
- Conditions
- Hip Arthropathy, Hip Osteoarthritis, Hip Pain Chronic
- Trial name
- NCT06083428
- Testing
- Ropivacaine 0.2% Injectable Solution Erector Spinae Plane Block, Ropivacaine 0.2% Injectable Solution - PENG block, Control Test
- Where
- Poland
- Volunteers
- 90 people
- Sponsor
- Poznan University of Medical Sciences