Clinical trials: Chronic Arthritis
Medication Adherence, Medication Compliance
Connected Healthcare for Individuals Living at Home With Chronic Conditions
Managing and taking medications as prescribed can be a difficult task. This is especially true for older adults living at home with chronic conditions while managing multiple prescribed medications.
- Conditions
- Medication Adherence, Medication Compliance, Medication Nonadherence, Hypertension
- Trial name
- NCT04339296
- Testing
- Spencer
- Where
- Canada
- Volunteers
- 91 people, healthy volunteers welcome
- Sponsor
- Alberta Health Services, Calgary
Hip Osteoarthritis, Hip Arthropathy
PENG Block for Total Hip Arthroplasty
This randomized, double-blinded, placebo-controlled trial seeks to evaluate the efficacy of the pericapsular nerve group block on postoperative rehabilitation.
- Conditions
- Hip Osteoarthritis, Hip Arthropathy, Hip Disease, Hip Pain Chronic
- Trial name
- NCT05944380
- Testing
- Ropivacaine 0.5% Injectable Solution, 0,9% normal saline
- Where
- Poland
- Volunteers
- 556 people, healthy volunteers welcome
- Sponsor
- Poznan University of Medical Sciences
Sacroiliitis
Intraartecular Platelet Rich Plasma for Sacroiliitis
Comparison between the effect of steroids and platelet-rich plasma on low back pain after ultrasound-guided sacroiliac injection to determine any is more effective and of long duration
- Trial name
- NCT03834480
- Testing
- Ultrasound guided Sacroiliac intra-articular injection
- Where
- Egypt
- Volunteers
- 2 people
- Sponsor
- Mansoura University
Osteoarthritis, Knee
Positive Minds Strong Joints for Knee Osteoarthritis
The aim of this research study is to test the feasibility of a physical and mental health intervention (Positive Minds, Strong Joints or PMSJ) for Black adults with knee osteoarthritis (OA).
- Trial name
- PMSJ (NCT06493903)
- Testing
- Positive Minds, Strong Joints
- Where
- United States
- Volunteers
- 39 people
- Sponsor
- Boston University Charles River Campus
Osteoarthritis
Chronic Pain Master Protocol (CPMP): A Study of LY3016859 in Participants With Osteoarthritis
This study is being done to test the safety and efficacy of LY3016859 for the treatment of osteoarthritis pain. This trial is part of the chronic pain master protocol H0P-MC-CPMP (NCT05986292) which is a protocol to accelerate…
- Trial name
- NCT04456686
- Testing
- LY3016859
- Where
- 33 sites in United States, Puerto Rico
- Volunteers
- 117 people
- Sponsor
- Eli Lilly and Company
Knee Pain Chronic
Genicular RFT vs Phenol Management in Patients With Knee Osteoarthritis
The aim of this study was to compare the efficacy of phenol and radiofrequency ablation for genicular nerve neurolysis in severe knee pain.
- Trial name
- NCT05908942
- Testing
- Nerve ablation
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 64 people
- Sponsor
- Diskapi Teaching and Research Hospital
Osteoarthritis, Knee, Pain, Chronic
Management of Knee Pain by Cooled Radiofrequency in Classical Anatomical Targets and Revised Targets
Osteoarthritis (OA) is a chronic and progressive disease that results from characteristic pathological changes in the tissues of the entire joint, resulting in failure in the component parts.
- Conditions
- Osteoarthritis, Knee, Pain, Chronic, Analgesia
- Trial name
- NCT05363241
- Testing
- Cooled radiofrequency in classical targets (CRF-CT), Cooled radiofrequency in revised targets (CRF-RT)
- Where
- Brazil
- Volunteers
- 10 people
- Sponsor
- Universidade Federal de Alfenas
Knee Osteoarthritis
Investigating Racial Differences in Diet Benefits for Knee Osteoarthritis
Knee osteoarthritis (OA) is the most prevalent form of arthritis and race is a risk factor for poor outcomes. African-Americans (AAs) report greater OA-related disability and pain severity compared to their Non-Hispanic White…
- Trial name
- NCT04343716
- Testing
- Low-carbohydrate diet
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- University of Alabama at Birmingham
Diabetes Mellitus, Congestive Heart Failure
Relative Impacts on Preventative Primary Care--a Longitudinal Evaluation of COVID-19:Phase 1
The goal of this observational study is to describe the impacts of COVID-19 on primary care chronic condition management in Canada within various patient populations.
- Conditions
- Diabetes Mellitus, Congestive Heart Failure, Chronic Kidney Diseases, Chronic Obstructive Pulmonary Disease
- Trial name
- RIPPLE-C (NCT05813652)
- Testing
- Pre-pandemic time period (Jun 22, 2018 to March 12, 2020), Peri-pandemic time period (March 13, 2020 to December 3, 2021)
- Where
- Canada
- Volunteers
- 919,928 people
- Sponsor
- McMaster University
Knee Disease, Knee Deformity
Ultrasound-Guided Adductor Canal Block for Total Knee Arthroplasty Surgery
The ultrasound-guided selective blockade of the saphenous nerve in the adductor canal provides effective analgesia and reduces postoperative pain in patients undergoing arthroscopic medial meniscectomy.
- Conditions
- Knee Disease, Knee Deformity, Knee Pain Chronic, Knee Arthropathy
- Trial name
- NCT06084403
- Testing
- 20 ml volume adductor canal block, 30 ml volume adductor canal block, 40 ml volume adductor canal block
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Bursa City Hospital
Osteoarthritis (OA)
HypnoPain Relief for OA
The goal of this clinical trial is to learn whether HypnoPain Relief (HPR), a brief clinical hypnosis intervention, can help reduce pain and improve quality of life in adults with osteoarthritis.
- Trial name
- HPR (NCT07850271)
- Testing
- HypnoPain Relief (HPR), Neutral Visual Exposure Waitlist Control
- Where
- Indonesia
- Volunteers
- 50 people
- Sponsor
- Gadjah Mada University
Rheumatology, Cardiovascular Diseases
Cardiovascular Risk and Chronic Inflammatory Rheumatism
Chronic inflammatory rheumatism and inflammation can increase the risk of cardiovascular problems. Indeed, these diseases can increase the risk of myocardial infarction.
- Conditions
- Rheumatology, Cardiovascular Diseases, Arthritis, Rheumatoid, Spondyloarthritis
- Trial name
- RCVRIC (NCT03187444)
- Testing
- Examinations
- Where
- France
- Volunteers
- 200 people
- Sponsor
- University Hospital, Clermont-Ferrand
Knee Osteoarthritis, Knee Arthritis
Dexamethasone vs. Dexmedetomidine for ESPB in Pain Management After Knee Arthroplasty
Effect of perineurial dexamethasone and dexmedetomidine on erector spinal plane block duration for knee arthroplasty
- Conditions
- Knee Osteoarthritis, Knee Arthritis, Knee Disease, Knee Pain Chronic
- Trial name
- NCT06470100
- Testing
- 0.9% Sodium Chloride Injection, Dexamethasone, Dexmedetomidine
- Where
- Poland
- Volunteers
- 90 people
- Sponsor
- Poznan University of Medical Sciences
Spinal Spondyloarthropathies, Axial Spondyloarthritis
Diagnostic Criteria in the Diagnosis of Spinal Spondyloarthropathies in Patients With Chronic Low Back Pain (Study P05320)(COMPLETED)
This is a multi-national, multi-site, observational study to determine which of two strategies, when used by referring physicians is superior in the diagnosis of axial spondyloarthritis (AS) by rheumatologists.
- Trial name
- NCT00726765
- Volunteers
- 1,090 people
- Sponsor
- Merck Sharp & Dohme LLC
Osteo Arthritis Knee and Hip, Low Back Pain
COMPARATIVE EFFECTIVENESS OF EXERCISE, COGNITIVE BEHAVIOURAL THERAPY, AND THEIR COMBINATION FOR PEOPLE WITH CHRONIC MUSCULOSKELETAL PAIN AND POOR SLEEP: SLEEPFIT TRIAL
This study aims to find out which lifestyle approach works best for people with chronic musculoskeletal pain (such as low back pain or hip/knee osteoarthritis) who also have poor sleep.
- Conditions
- Osteo Arthritis Knee and Hip, Low Back Pain, Insomnia
- Trial name
- SLEEPFIT (NCT07532070)
- Testing
- Aerobic physical activity, CBT-I, Combined aerobic physical activity and CBT-I
- Where
- 4 sites in United States, Australia
- Volunteers
- 384 people
- Sponsor
- University of Sydney
Arthritis, Reactive, Reiter Disease
Combination Antibiotic Treatment for Reactive Arthritis Caused by Chlamydia Bacteria
Reactive arthritis, also known as Reiter's syndrome, is a form of arthritis that occurs as a reaction to an infection elsewhere in the body. It is characterized by inflammation of the joints, tendons, urogenital tract, and eyes.
- Trial name
- NCT00351273
- Testing
- Doxycycline and Rifampin, Azithromycin and Rifampin
- Where
- 3 sites in United States, Canada
- Volunteers
- 42 people
- Sponsor
- University of South Florida
Pain, Chronic
The Turkish Cross-Cultural Adaptation, Validity and Reliability of VMPCI
This study was planned to adapt the Vanderbilt Multidimensional Pain Coping Inventory into Turkish, to investigate its cultural adaptation, validity and reliability.
- Trial name
- NCT04258384
- Testing
- survey application
- Where
- Turkey (Türkiye)
- Volunteers
- 352 people
- Sponsor
- Yeditepe University
Ankylosing Spondylitis, Low Back Pain
The Effect of Acupuncture in Treating Chronic Low-back Pain
The purpose of this study is to evaluate the efficiency of acupuncture in treating chronic low-back pain
- Trial name
- NCT02260284
- Testing
- Yaotong points acupuncture, the usual care, standardized acupuncture
- Where
- China
- Volunteers
- 160 people
- Sponsor
- Chengdu PLA General Hospital
Osteoarthritis of Knee
Assessment of the Safety and Efficacy of 3VM1001 Cream for Treatment of Chronic Pain Caused by Knee Osteoarthritis.
3VM1001 is a topical cream that may be useful for the treatment of chronic osteoarthritis of the knee. This proof of concept study is a randomized, placebo-controlled, double-blind study to compare treatment with 3VM1001 cream to…
- Trial name
- NCT02332148
- Testing
- 3VM1001
- Volunteers
- 50 people
- Sponsor
- CDA Research Group, Inc.
Osteoarthritis of Knee
Electrical Dry Needling Versus Iontophoresis in Treating Chronic Unilateral Knee Osteoarthritis
The goal of this clinical trial is to compare the effects of electrical dry needling versus glucosamine sulfate iontophoresis on pain intensity level, functional ability, and knee range of motion in chronic unilateral knee…
- Trial name
- NCT06578663
- Testing
- conventional physical therapy, Electrical Dry Needling, Glucosamine sulfate iontophoresis
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Horus University