Clinical trials: Chronic Asthma
COPD, Asthma
A Pharmacist-Led Intervention to Increase Inhaler Access and Reduce Hospital Readmissions (PILLAR)
The goal of this study is to assess the impact of pharmacist-led benefits investigations and application of clinical practice guidelines on patient access to inhalers and time to hospital readmission or Emergency Department (ED)…
- Trial name
- PILLAR (NCT03927820)
- Testing
- Benefits investigation
- Where
- United States
- Volunteers
- 914 people
- Sponsor
- Vanderbilt University Medical Center
Asthma
Extended Safety Study of Montelukast in Infants and Young Children With Chronic Asthma (0476-232)
Patients were treated with either montelukast 4 mg oral granules or usual care. Patients who completed Protocol MK0476-176-01 (NCT00943683) had the option to enroll in this study.
- Trial name
- NCT00943397
- Testing
- montelukast sodium, Comparator: Usual Care
- Volunteers
- 190 people
- Sponsor
- Organon and Co
Asthma
Comparison of RPL554 With Placebo and Salbutamol in Asthmatic Patients
The number of people with of asthma and allergy is still increasing and a large number of patients still do not have their asthma well controlled.
- Trial name
- NCT02427165
- Testing
- RPL554, Salbutamol
- Where
- 2 sites in Sweden, United Kingdom
- Volunteers
- 29 people
- Sponsor
- Verona Pharma, Inc., a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA
COPD, Asthma
AirSonea Wheeze Detection Study
The purpose of this study is to determine if the AirSonea device provides an objective assessment of breath sounds for the presence of wheeze in both medical and home environments.
- Trial name
- NCT01927172
- Testing
- AirSonea
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- iSonea
Cardiovascular Disease, Heart Failure
Integration of Chronic Disease Rehabilitation Services Into Primary Care
The aim of PR1MaC is to establish a clinical intervention that will adapt and permanently integrate rehabilitation services into primary care settings, which would be the reference point in the health care system for people with…
- Conditions
- Cardiovascular Disease, Heart Failure, Chronic Obstructive Pulmonary Disease, Asthma
- Trial name
- PR1MaC (NCT01319656)
- Testing
- Support, management, educational, counselling, follow-up
- Where
- Canada
- Volunteers
- 326 people
- Sponsor
- Martin Fortin
COVID-19, Long COVID
Using Data From a Multisensor Rapid Health Assessment Device to Predict Decompensation in Long COVID (AIDI)
We are conducting a research study at the VA hospital in Bedford, MA to learn more about how a multisensor rapid health assessment device, MouthLab, can help predict or anticipate future health complications in patients with…
- Trial name
- AIDI (NCT05713266)
- Testing
- MouthLabTM
- Where
- United States
- Volunteers
- 204 people, healthy volunteers welcome
- Sponsor
- Edith Nourse Rogers Memorial Veterans Hospital
Asthma, COPD
Prehospital Emergency Care of Obstructive Respiratory Emergencies With the Use of Teleconsultation
The aim of the study is to investigate the quality of prehospital emergency care in acute respiratory emergencies, when paramedics are supported telemedically by an EMS physician.
- Trial name
- NCT01644045
- Testing
- Teleconsultation
- Where
- Germany
- Volunteers
- 17 people
- Sponsor
- RWTH Aachen University
Chronic Obstructive Pulmonary Disease
Safety, Tolerability and Pharmacokinetics of Multiple Ascending Doses of AZD8871 in Healthy Subjects
AZD8871 is a new chemical entity possessing long-acting effect in a single molecule which presents a novel treatment approach to chronic obstructive pulmonary disease [COPD] and potentially also asthma (in combination with an…
- Trial name
- NCT02814656
- Testing
- AZD8871
- Where
- United Kingdom
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Bronchial Asthma
Risk of Chronic Kidney Disease in Bronchial Asthma
the study aims to determine the frequency and factors associated with chronic kidney disease among asthmatic patients in order to determine persons who are at risk of developing chronic kidney disease and require strict follow up…
- Trial name
- NCT06472596
- Testing
- CBC, CRP ,ESR, ABG , interleukin 6, tumor necrotic factor alpha
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Sohag University
Infection, Heart Failure
Home Hospital for Suddenly Ill Adults
The investigators propose a home hospital model of care that substitutes for treatment in an acute care hospital. Limited studies of the home hospital model have demonstrated that a sizeable proportion of acute care can be…
- Conditions
- Infection, Heart Failure, COPD, Asthma
- Trial name
- NCT03524222
- Testing
- Home Hospitalization
- Where
- 2 sites in United States
- Volunteers
- 3,000 people
- Sponsor
- Brigham and Women's Hospital
Asthma, COPD
Small Airway Obstruction in Asthma, COPD, ACOS
This study was designed as retrospective chart review to test our hypothesis whether there are the differences in inflammatory and anti-inflammatory mediators between asthmatic and ACOS patients with small airway obstruction, and…
- Conditions
- Asthma, COPD, Asthma-COPD Overlap Syndrome
- Trial name
- NCT03423693
- Testing
- No any intervention
- Where
- Thailand
- Volunteers
- 230 people
- Sponsor
- Mahidol University
COPD, Asthma
Participatory Action Research to Evaluate the Delivery of the MISSION ABC Service Model and Assess Health Service and Clinical Outcomes
Innovations aimed at improving new patient identification, diagnosis, nonpharmacological treatment, supported self-management, and remote monitoring, together with new methods of clinical support could improve outcomes in…
- Conditions
- COPD, Asthma, Breathlessness
- Trial name
- NCT03096509
- Testing
- MISSION ABC Integrated Care clinic
- Where
- United Kingdom
- Volunteers
- 342 people
- Sponsor
- Portsmouth Hospitals NHS Trust
Asthma
A Study of MK0359 in Patients With Chronic Asthma (0359-013)
A study to test the effect of MK0359 in lessening the symptoms of asthma as compared to placebo.
- Trial name
- NCT00482898
- Testing
- MK0359
- Volunteers
- 56 people
- Sponsor
- Merck Sharp & Dohme LLC
Asthma, Chronic Obstructive Pulmonary Disease
Detecting Errors In Using Metered Dose Inhalers (MDI) Among Asthma And Chronic Obstructive Pulmonary Disease (COPD) Patients
Metered Dose Inhaler (MDI) and Dry Powdered Inhaler (DPI) are the two most common devices used to deliver medicine in conditions such as asthma and chronic obstructive pulmonary disease.
- Trial name
- NCT02447575
- Testing
- Education on Use of MDI
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- Baylor College of Medicine
Asthma, Coronary Artery Disease
A Study of the Safety and Tolerance of Regadenoson in Subjects With Asthma or Chronic Obstructive Pulmonary Disease
This study is intended to determine the safety and tolerance of regadenoson in subjects with asthma or chronic obstructive pulmonary disease.
- Conditions
- Asthma, Coronary Artery Disease, Pulmonary Disease, Chronic Obstructive
- Trial name
- NCT00862641
- Testing
- Regadenoson
- Where
- 48 sites in United States
- Volunteers
- 1,009 people
- Sponsor
- Astellas Pharma Inc
Asthma
Initiation of Chronic Asthma Care Regimens in the Pediatric Emergency Department
Hypothesis: Initiating chronic management treatment plans in conjunction with an asthma educational intervention in the pediatric Emergency Department (ED) with anti-inflammatory medication will result in an improvement of ED…
- Trial name
- IRUSBUPR0045 (NCT00388739)
- Testing
- Intervention: Budesonide, Usual care: albuterol + systemic steroids
- Where
- United States
- Sponsor
- Baylor College of Medicine
Asthma, COPD
SADT in COPD and Oscillometry in Obstructive Airway Disease in Primary Care. The SCOOP-study
Rationale: The Small Airways are a major site of obstruction in many respiratory diseases, including COPD. More insight into a diagnosis of Small Airways Dysfunction (SAD) in patients with COPD is clinically valuable as it might…
- Conditions
- Asthma, COPD, Small Airway Disease
- Trial name
- SCOOP (NCT07374172)
- Testing
- Oscillometer ALDS
- Where
- Netherlands
- Volunteers
- 108 people
- Sponsor
- General Practitioners Research Institute
Asthma Chronic, Cough
ToAST:Investigating the Effect of Bronchial Thermoplasty on Cough in Patients With Severe Asthma
ToAST study is a pilot study aiming to establish the safety profile of using inhaled capsaicin challenge in patients with severe asthma.
- Trial name
- ToAST (NCT03281941)
- Testing
- Inhaled capsaicin cough challenge
- Where
- United Kingdom
- Volunteers
- 24 people
- Sponsor
- National Health Service, United Kingdom
Small Airway Disease, Asthma
Small Airways Disease (SAD) in Severe Asthma as a Novel Endpoint and Distinct Target for Mepolizumab (SASAM Study)
Rationale Although the majority of asthma patients can be effectively treated with currently available medications, a substantial subset remains severe, causing a considerable proportion of resource expenditure.
- Trial name
- SASAM (NCT05040997)
- Testing
- Small airways assessment
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Respiratory Disease, Asthma
A System to Classify Treatable Traits in Primary Care
This study proposes an approach to address an urgent unmet need in clinical practice, namely a pragmatic method of establishing what is the cause of a patient's complaint and the next steps to address this problem.
- Conditions
- Respiratory Disease, Asthma, Copd
- Trial name
- SMART (NCT05357274)
- Testing
- Diagnostic testing
- Where
- Ireland
- Volunteers
- 200 people
- Sponsor
- Royal College of Surgeons, Ireland