Clinical trials: Chronic Asthma
COPD, Asthma
Cardiorespiratory Diagnostic Study
This study uses a new breathing device called 'N-Tidal C' handset which measures breathing patterns. Investigators have found that people with cardiac and respiratory illnesses breathe out a gas, called carbon dioxide (CO2), in a…
- Conditions
- COPD, Asthma, Lung Cancer, Anemia
- Trial name
- CARES (NCT04939558)
- Testing
- N-Tidal C handset
- Where
- United Kingdom
- Volunteers
- 744 people, healthy volunteers welcome
- Sponsor
- TidalSense
Asthma, Allergy
The Leaky Lung Test
This is a clinical trial designed to test the hypothesis that measuring the absorption and excretion of inhaled mannitol will provide a clinically useful marker of airway epithelial permeability in asthma.
- Conditions
- Asthma, Allergy, Reactive Airway Disease, Lung Diseases, Obstructive
- Trial name
- NCT02306473
- Testing
- Mannitol
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Rochester
Asthma, Chronic Obstructive Pulmonary Disease (COPD), or Chronic Lung Disease (E.G., Chronic Bronchitis and Restrictive Lung Diseases Such as Asbestosis), The Effect of Yoga, Paranayama Yoga Practice on Respiratory Diseases
EFFECT OF PRANAYAMA YOGA ON COPD
The aim of the study In this study, pranayama yoga practices are the sub-dimensions of respiratory parameters, symptom and disease affection level, psychosocial adjustment and psychosocial adjustment in individuals with COPD.
- Trial name
- COPD (NCT06022627)
- Testing
- Pranayama Yoga
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Yeditepe University
Asthma
Better Pediatric Asthma Outcomes Through Chronic Care
This 3-year, multi-site study focuses on the translation of cost-effective methods to bring a chronic care model to the care of poor, minority, inner-city children with asthma, at risk of the worst outcomes for the leading…
- Trial name
- NCT00355069
- Testing
- electronic (computer based) provider feedback tool
- Where
- United States
- Volunteers
- 548 people
- Sponsor
- UConn Health
Asthma, Mastocytosis
Mast Cell Activation Test in Allergic Disease
Activation of mast cells in the immune system is known to cause allergic reactions sometimes with severe systemic symptoms. The investigators have recently developed a blood-based mast cell activation diagnostic test in which…
- Conditions
- Asthma, Mastocytosis, Mast Cell Activation Syndrome, Food Allergy
- Trial name
- NCT03406325
- Where
- Hong Kong
- Volunteers
- 19 people
- Sponsor
- Hong Kong Sanatorium & Hospital
COPD (Chronic Obstructive Pulmonary Disease), Asthma Copd
Self-Management in Adults With Asthma or COPD
This study is a single-blind (evaluator-blind), parallel-group randomized controlled trial comparing two approaches to home-based pulmonary rehabilitation self-management training in individuals with chronic respiratory disease…
- Trial name
- NCT07742085
- Testing
- Video Animation, brochure education
- Where
- Turkey (Türkiye)
- Volunteers
- 104 people
- Sponsor
- Mustafa Kemal University
Pulmonary Disease, Chronic Obstructive, Asthma
Lung Deposition of the BDP/Formoterol Combination Administered Via the NEXT DPI in Healthy, Asthmatic and COPD Patients
The purpose of this study is to investigate the lung deposition and distribution pattern of Beclometasone and Formoterol using a gamma-scintigraphic technique after inhalation of a single dose of 99mTc-radiolabelled…
- Trial name
- NCT01176747
- Testing
- BDP/formoterol NEXT DPI
- Where
- Germany
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Chiesi Farmaceutici S.p.A.
Asthma, Chronic Obstructive Pulmonary Disease
Study of the Metabolism of Two Magnesium Supplements in Healthy Volunteers
The present study is part of a project titled 'Magnesium in asthma and chronic obstructive pulmonary disease'. The hypothesis of the main project is that daily magnesium supplement will benefit patients with asthma and chronic…
- Trial name
- NCT01113138
- Testing
- Mablet (Magnesium-supplement), Magnesium Sulfate
- Where
- Denmark
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Emphysema, Acute Respiratory Distress Syndrome
Use of the Hattler Respiratory Assist Catheter in Severe Respiratory Failure
A new artificial lung device has been developed that potentially provides added support to mechanical ventilation for severely damaged lungs.
- Conditions
- Emphysema, Acute Respiratory Distress Syndrome, Chronic Obstructive Pulmonary Disease, Asthma
- Trial name
- NCT00288964
- Testing
- Hattler Respiratory Assist Catheter
- Where
- United Kingdom
- Sponsor
- Alung Technologies
Pulmonary Disease, Chronic Obstructive, Asthma
Tolerability of Metoprolol-Succinate-ER and Carvedilol in COPD
Use of beta-blockers has proven beneficial in patients with hypertension, heart failure, and in people who have suffered a heart attack.
- Conditions
- Pulmonary Disease, Chronic Obstructive, Asthma, Adverse Effect of Beta-adrenoreceptor Antagonists
- Trial name
- NCT03370835
- Testing
- Metoprolol succinate ER, Carvedilol
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- VA Greater Los Angeles Healthcare System
Asthma (Diagnosis), COPD (Chronic Obstructive Pulmonary Disease)
The Impact of Extreme Heat Waves and Air Pollution on the Prognosis of Chronic Airway Diseases
Extreme heat waves (EHW) and air pollution exacerbate chronic airway diseases, but little is known about how these environmental stressors affect quality of life, airway inflammation, symptom control, and pulmonary function.
- Trial name
- NCT07261774
- Where
- Turkey (Türkiye)
- Volunteers
- 96 people
- Sponsor
- Mersin University
Asthma (Diagnosis)
Resources and Education for Addressing Chronic Health (REACH)
This study pilots REACH, Resources and Education for Addressing Chronic Health, a service model to facilitate care coordination and communication across medical, school, and home settings.
- Trial name
- REACH (NCT07819747)
- Testing
- REACH
- Where
- United States
- Volunteers
- 430 people
- Sponsor
- Washington University School of Medicine
Asthma Chronic
Pilot Voice Sample Collection From People With Asthma
Human speech is as unique as a fingerprint and analysing speech had advanced so much that speech can now be used instead of PIN numbers in banking.
- Trial name
- NCT04799678
- Testing
- Recording voice samples
- Volunteers
- 75 people
- Sponsor
- Thomas Antalffy
Asthma, Chronic Obstructive Pulmonary Disease
Use Of Capnography As Surrogate Measure Of PC02 In Medical Intensive Care Unit (ICU) Patients
The purpose of this study is to evaluate the use of Capnography (Continuous recording of the carbon dioxide content of expired air)as an alternative test to measure PC02 levels in patients with asthma, chronic obstructive…
- Conditions
- Asthma, Chronic Obstructive Pulmonary Disease, Interstitial Lung Disease
- Trial name
- NCT00744614
- Testing
- Capnography
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Lahey Clinic
Asthma, Asthma in Children
AeviceMD for Pediatric Asthma Management
A wearable remote patient monitor (AeviceMD) is to be used to monitor the respiratory health of pediatric asthma patients in this pilot study.
- Conditions
- Asthma, Asthma in Children, Pediatric Asthma, Chronic Respiratory Disease
- Trial name
- APAM (NCT06321471)
- Testing
- AeviceMD
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Irina Dralyuk
Asthma-COPD Overlap Syndrome, Vitamin D Deficiency
Impact of Vitamin D3 Administration on Cardiac Autonomic Tone in Asthma Chronic Obstructive Pulmonary Disease(COPD) Overlap Patients
Title:Impact of vitamin D administration on cardiac autonomic tone in Asthma Chronic Obstructive Pulmonary Disease (COPD) Overlap patients: A blinded randomized control trial.
- Conditions
- Asthma-COPD Overlap Syndrome, Vitamin D Deficiency, Cardiac Autonomic Tone
- Trial name
- COPD (NCT03773809)
- Testing
- Vitamin D capsule
- Where
- Bangladesh
- Volunteers
- 50 people
- Sponsor
- Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh
Tetraplegia, Asthma
Exhaled Breath Condensate Biomarkers of Inflammation in Individuals With Chronic Cervical Spinal Cord Injury
The purpose of this study is to obtain markers of airway inflammation from the exhaled breath condensate (the moisture in exhaled air) for comparison to blood based markers.
- Trial name
- NCT02235714
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- James J. Peters Veterans Affairs Medical Center
Chronic Rhinosinusitis With Nasal Polyps, Asthma
EValuating trEatment RESponses of Dupilumab Versus Omalizumab in Type 2 Patients
Primary Objective -To evaluate the efficacy of dupilumab compared to omalizumab in reducing the polyp size and improving sense of smell Secondary Objectives To evaluate the efficacy of dupilumab in improving chronic…
- Trial name
- EVEREST (NCT04998604)
- Testing
- Dupilumab, Omalizumab
- Where
- 87 sites in United States, Belgium and 15 more
- Volunteers
- 360 people
- Sponsor
- Sanofi
Chronic Obstructive Pulmonary Disease (COPD), Asthma
Disease Management in Asthma or Chronic Obstructive Pulmonary Disease (COPD) Patients
The purpose of this study is to determine whether disease management program is effective in preventing acute exacerbations in patients with unstable chronic obstructive pulmonary disease (COPD) or asthma.
- Trial name
- ACDM-Maccabi (NCT01101126)
- Testing
- Pulmonary disease management, Usual care
- Where
- 2 sites in Israel
- Volunteers
- 492 people
- Sponsor
- Sheba Medical Center
Asthma, Reactive Airway Disease
Single Oral Dose of Dexamethasone Versus Five Days of Prednisone in Adult Asthma
This study seeks to compare the effectiveness of a single dose of oral dexamethasone versus 5 days of oral prednisone in the treatment of mild to moderate asthma exacerbations to prevent relapse with an unscheduled return visit…
- Trial name
- NCT01241006
- Testing
- Dexamethasone, Prednisone
- Where
- United States
- Volunteers
- 376 people
- Sponsor
- Alameda County Medical Center