Clinical trials: Chronic Atrophic Gastritis
Atrophic Gastritis With Low-grade Intraepithelial Neoplasia
Fuzheng Nizeng Formula for Chronic Atrophic Gastritis With Low-grade Intraepithelial Neoplasia, a Multicenter Randomized Controlled Trial
Fuzheng Nizeng Formula (FZNZ) is derived from the classic formula Liujunzi Decoction. Former pilot study found that FZNZ promoted the recovery of gastric atrophy and relieve the relative symptoms.
- Trial name
- NCT06324825
- Testing
- Fuzhegn Nizeng Decoction, Moluodan granules
- Where
- China
- Volunteers
- 144 people
- Sponsor
- Peking University First Hospital
Chronic Atrophic Gastritis With Hyperplasia (Diagnosis)
Compound Granules of Hedyotis Diffusa for Chronic Atrophic Gastritis
Chronic atrophic gastritis is considered a premalignant lesion of gastric cancer. The development of gastric cancer usually follows the Correa sequence: chronic superficial gastritis → chronic atrophic gastritis → intestinal…
- Trial name
- NCT07391800
- Testing
- Compound Granules of Hedyotis diffusa
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine
CAG - Chronic Atrophic Gastritis, EGC - Early Gastric Cancer
LCI in Chronic Atrophic Gastritis and Early Gastric Cancer
Color change is a useful marker for the endoscopic identification of chronic atrophic gastritis (CAG) and gastric cancer (GC). Several histopathological studies have suggested a correlation between certain gastrointestinal…
- Trial name
- NCT06152263
- Testing
- Compare color information and mucosal microvascular density
- Where
- China
- Volunteers
- 10 people
- Sponsor
- Affiliated Hospital to Academy of Military Medical Sciences
Stomach Neoplasms
Lifestyle Intervention for Prevention of Gastric Neoplasm
The purpose of this study is to determine whether positive lifestyle interventions (diet modification and smoking cessation) are effective in the prevention of gastric pre-cancer and cancer occurrences and reccurence of gastric…
- Trial name
- NCT02679495
- Testing
- Active measures of lifestyle modification
- Where
- China
- Volunteers
- 350 people
- Sponsor
- Shandong University
Helicobacter Pylori, Early Gastric Cancer
Distribution Characteristics of Helicobacter Pylori
This study aimed to analyze the distribution characteristics of Helicobacter pylori（H. pylori） in varying stages of atrophic gastritis and early gastric cancer using immunohistochemical staining, with the goal of providing…
- Trial name
- NCT07253948
- Testing
- immunohistochemical testing
- Where
- China
- Volunteers
- 231 people
- Sponsor
- Jilin University
Gastric Cancer, Atrophic Gastritis
Screening of Gastric Cancer Via Breath Volatile Organic Compounds by Hybrid Sensing Approach
The study is aimed to determine the potential of volatile marker testing for gastric cancer screening. The study will be addressing the role of confounding factors, including lifestyle factors, diet, smoking as well as addressing…
- Conditions
- Gastric Cancer, Atrophic Gastritis, Gastric Dysplasia, H.Pylori Infection
- Trial name
- VOGAS (NCT04022109)
- Testing
- Breath sampling for VOC detection, Surgery material collection for VOC headspace analysis, Upper endoscopy
- Where
- 5 sites in Brazil, Chile and 3 more
- Volunteers
- 5,000 people
- Sponsor
- University of Latvia
Atrophic Gastritis, Intestinal Metaplasia
SUrveillance of PREMalignant Stomach - Individualized Endoscopic Follow-up
Introduction: Gastric atrophy and intestinal metaplasia are the principal precursors for gastric cancer and, therefore, are considered gastric premalignant conditions.
- Conditions
- Atrophic Gastritis, Intestinal Metaplasia, Gastric Dysplasia, Gastric Cancer
- Trial name
- SUPREME (NCT04613570)
- Testing
- Upper gastrointestinal endoscopy
- Where
- Portugal
- Volunteers
- 912 people
- Sponsor
- Instituto Portugues de Oncologia, Francisco Gentil, Porto
Chronic Atrophic Gastritis
Evaluation of the Efficacy of Electroacupuncture in the Treatment of Chronic Atrophic Gastritis
Brief Summary Template for the Study: This clinical trial aims to evaluate whether electroacupuncture can treat chronic atrophic gastritis (CAG) in adult subjects aged 18 to 75 years (including both males and females), all of…
- Trial name
- NCT07152860
- Testing
- 5 Hz electroacupuncture combined tipronone capsules, Simple tipronone capsules group(The basic treatment group)
- Where
- 3 sites in China
- Volunteers
- 100 people
- Sponsor
- Yi Liang
Chronic Atrophic Gastritis
Clinical Study of Umbilical Cord Blood Mononuclear Cell Therapy for the Treatment of Chronic Atrophic Gastritis
To evaluate the efficacy and safety of umbilical cord blood mononuclear cells in the treatment of chronic atrophic gastritis.
- Trial name
- NCT05808010
- Testing
- Mononuclear cells, Weifuchun+Hydrotalcite/L-Glutamine and Sodium Gualenate Granules
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Shandong Provincial Hospital
Atrophic Gastritis
Usefulness of Serum Pepsinogen and Gastrin as the Predictive Biomarker of Atrophic Gastritis, Intestinal Metaplasia and Gastric Cancer in Korea
It is well-known that atrophic gastritis is a major risk factor for gastric cancer, which leads to variations in the serum levels of gastrin, pepsinogen (PG) I, and PGII.
- Trial name
- NCT02184910
- Testing
- pepsinogen and gastrin
- Where
- South Korea
- Volunteers
- 108 people
- Sponsor
- Yonsei University
Chronic Atrophic Gastritis
Treatment of Atrophic Gastritis After HP Eradication With Modified Liujunzi Decoction Based on Syndrome Differentiation
This is an observational cohort study of clinical efficacy study.The purpose of this topic is to evaluate the efficacy and safety of Modified Liujunzi Decoction based on syndrome differentiation in patients with chronic atrophic…
- Trial name
- NCT05388890
- Testing
- MLD, WFC
- Where
- China
- Volunteers
- 286 people
- Sponsor
- Peking University First Hospital
Helicobacter Pylori Infection, Atrophic Gastritis
Artificial Intelligence for Determination of Gastroscopy Surveillance Intervals
The purpose of this study is to develop and validate a clinical decision support system based on automated algorithms. This system can use natural language processing to extract data from patients' endoscopic reports and…
- Conditions
- Helicobacter Pylori Infection, Atrophic Gastritis, Intestinal Metaplasia, Low Grade Intraepithelial Neoplasia
- Trial name
- NCT05631015
- Testing
- AI recongnize disease and generate recommendations
- Where
- China
- Volunteers
- 2,000 people
- Sponsor
- Xiuli Zuo
Flow Determination
Real-time Observation of Microcirculatory Hemodynamics in Gastric Intestinal Metaplasia by Confocal Laser Endomicroscopy
The morphologic change of microvessels has the clinical value to distinguish cancerous from non-cancerous mucosa. The aim of this study was to observe gastric mucosa microcirculatory hemodynamic changes real-time using pCLE…
- Trial name
- NCT02595151
- Testing
- CLE
- Where
- China
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Shandong University
Gastric Cancer
Microbiota and Metabolomics of Intestinal Type of Gastric Cancer
Compare with the gastric cavity without cancerous transformation in atrophic gastritis, analyze the microbiota and metabolomics changes in intestinal type of gastric cancer under the background of atrophic gastritis, and explore…
- Trial name
- NCT06079554
- Where
- China
- Volunteers
- 32 people
- Sponsor
- Jilin University
Chronic Atrophic Gastritis (CAG)
To Evaluate the Efficacy and Safety of Vitamin B12 Contains Extract of Lamb's Stomach in Treatment of Chronic Atrophic Gastritis (CAG)
The purpose of this study is to determine whether Gastropyloric Complex Capsules are safe and effective in the treatment of chronic atrophic gastritis (CAG).
- Trial name
- NCT01474044
- Testing
- Gastropylor Complex Capsules
- Where
- China
- Volunteers
- 851 people
- Sponsor
- Xinjiang Biochemical Pharmaceutical Co., Ltd.
Atrophic Gastritis
Grading Atrophic Gastritis by Confocal Laser Endomicroscopy Probe (p-CLE)
Atrophic gastritis (AG) is a chronic disease, associated to gastric adenocarcinoma moreover if severity AG is present. Sydney system classified AG as mild, moderate and severe, but with moderate interobserver agreement, due to…
- Trial name
- NCT02351154
- Testing
- Cellvizio Viewer software
- Where
- Ecuador
- Volunteers
- 30 people
- Sponsor
- Instituto Ecuatoriano de Enfermedades Digestivas
Intestinal Metaplasia, Chronic Gastritis
UC Davis Cohort of Pre-Malignant and Malignant Gastro-Intestinal DisEases Study
The UC Davis Cohort of Pre-Malignant and Malignant GastroIntestinal DisEases (TUMMIE) Study is a prospective longitudinal cohort study designed to improve understanding of the natural history, risk factors, and biological…
- Conditions
- Intestinal Metaplasia, Chronic Gastritis, Atrophic Gastritis, Autoimmune Gastritis
- Trial name
- TUMMIE (NCT05021029)
- Where
- United States
- Volunteers
- 1,000 people
- Sponsor
- University of California, Davis
Chronic; Gastritis, Atrophic
Assessment of the Role of Incisura Biopsy in the Staging of Chronic Gastritis
This prospective multicenter study investigates the added benefit of incisura biopsy to correct identification of patients with high-risk chronic gastritis (OLGA stages III-IV).
- Trial name
- INCREASE (NCT05744596)
- Testing
- Incisura biopsy analysis
- Where
- 2 sites in Portugal, Romania
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Clinical Hospital Colentina
Risk Assessment of Chronic Atrophic Gastritis Malignant Transformation
Risk Assessment and Syndrome Evolution Models for Chronic Atrophic Gastritis Malignant Transformation
Chronic atrophic gastritis (CAG) is acknowledged as the precancerous stage of gastric cancer (GC). The present study aims to developed risk assessment and syndrome evolution models of CAG malignant transformation events combining…
- Trial name
- NCT03261934
- Testing
- No intervention
- Where
- 2 sites in China
- Volunteers
- 2,000 people
- Sponsor
- Beijing University of Chinese Medicine
Chronic Atrophic Gastritis, Hypergastrinemia
YF476 and Type I Gastric Carcinoids (Norway)
The aim of the study is to find out if the experimental medicine, YF476, can make gastric carcinoids, a rare type of stomach tumour, shrink and disappear.
- Conditions
- Chronic Atrophic Gastritis, Hypergastrinemia, Type I Gastric Carcinoids
- Trial name
- NCT01444014
- Testing
- YF476
- Where
- Norway
- Volunteers
- 8 people
- Sponsor
- Trio Medicines Ltd.