Clinical trials: Chronic Atrophic Gastritis
Chronic Atrophic Gastritis
The Study of Chinese Medicine for the Treatment of Chronic Atrophic Gastritis
The purpose of this study is to evaluate efficacy of Chinese medicine treatment for chronic atrophic gastritis. It is a multi-center, randomized, placebo-controlled trial.
- Trial name
- NCT02955134
- Testing
- Talcid®, Chinese medicine prescription, Compound Azimtamide Entieric-coated Tablets
- Where
- 13 sites in China
- Volunteers
- 468 people
- Sponsor
- Wangjing Hospital, China Academy of Chinese Medical Sciences
Atrophic Gastritis, Artificial Intelligence
AI-assisted White Light Endoscopy to Identify the Kimura-Takemoto Classification of Atrophic Gastritis
Grading endoscopic atrophy according to the Kimura-Takemoto classification can assess the risk of gastric neoplasia development.
- Conditions
- Atrophic Gastritis, Artificial Intelligence, Endoscopy
- Trial name
- NCT05916014
- Testing
- Diagnostic Test: The diagnosis of Artificial Intelligence and endosopists
- Where
- China
- Volunteers
- 1,500 people
- Sponsor
- Shandong University
Atrophic Gastritis
Usefulness of Serum Pepsinogen and Gastrin as the Predictive Biomarker of Atrophic Gastritis, Intestinal Metaplasia and Gastric Cancer in Korea
It is well-known that atrophic gastritis is a major risk factor for gastric cancer, which leads to variations in the serum levels of gastrin, pepsinogen (PG) I, and PGII.
- Trial name
- NCT02184910
- Testing
- pepsinogen and gastrin
- Where
- South Korea
- Volunteers
- 108 people
- Sponsor
- Yonsei University
Helicobacter Pylori, Gastric Antrum
Value of Additional Corpus Biopsy for Diagnosis of H Pylori in Atrophic Gastritis. Prospective Non-randomized Study
There are controversies about the best sites -biopsy based -tests for H pylori associated gastritis. The study is designed to evaluate the optimal site of gastric mucosal biopsy for identification of Helicobacter pylori…
- Conditions
- Helicobacter Pylori, Gastric Antrum, CORPUS BIOPSIES
- Trial name
- NCT02675010
- Testing
- ENDOSCOPIC GASTRIC BIOPSIES FROM ANTRUM AND BODY
- Where
- Egypt
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Gastric Cancer, Intestinal Metaplasia
Prediction of Gastric Cancer in Intestinal Metaplasia and Atrophic Gastritis
The primary objectives of this study are: To identify clinical or histological factors associated with gastric cancer development in patients with IM and AG To establish a machine learning algorithm for prediction of future…
- Conditions
- Gastric Cancer, Intestinal Metaplasia, Atrophic Gastritis
- Trial name
- GIMA (NCT04840056)
- Where
- Hong Kong
- Volunteers
- 1,300 people
- Sponsor
- Chinese University of Hong Kong
Chronic Atrophic Gastritis, Hypergastrinemia
YF476 and Type I Gastric Carcinoids (Norway)
The aim of the study is to find out if the experimental medicine, YF476, can make gastric carcinoids, a rare type of stomach tumour, shrink and disappear.
- Conditions
- Chronic Atrophic Gastritis, Hypergastrinemia, Type I Gastric Carcinoids
- Trial name
- NCT01444014
- Testing
- YF476
- Where
- Norway
- Volunteers
- 8 people
- Sponsor
- Trio Medicines Ltd.
Atrophic Gastritis
Grading Atrophic Gastritis by Confocal Laser Endomicroscopy Probe (p-CLE)
Atrophic gastritis (AG) is a chronic disease, associated to gastric adenocarcinoma moreover if severity AG is present. Sydney system classified AG as mild, moderate and severe, but with moderate interobserver agreement, due to…
- Trial name
- NCT02351154
- Testing
- Cellvizio Viewer software
- Where
- Ecuador
- Volunteers
- 30 people
- Sponsor
- Instituto Ecuatoriano de Enfermedades Digestivas
Atrophic Gastritis
Observation on the Efficacy of Radiofrequency Ablation for Patients With Moderate to Severe Gastric Atrophy With Enterosis With or Without Atrophy of Intraepithelial Neoplasia: An Observational Study
The aim of this observational study was to understand the effect of radiofrequency ablation on subjects with moderate to severe gastric atrophy with enterocolitis with or without low-grade intraepithelial neoplasia who underwent…
- Trial name
- NCT06751212
- Testing
- Radiofrequency ablation alone
- Volunteers
- 62 people
- Sponsor
- Xiuli Zuo
Gastric Cancer, Gastric Intestinal Metaplasia
Chemoprevention of Gastric Carcinogenesis
A clinical study of the efficacy of oral alpha-difluoromethylornithine (eflornithine or DFMO) in male and female subjects ages 30-60 with gastric premalignant lesions in two high risk regions of Latin America.
- Trial name
- NCT02794428
- Testing
- Eflornithine
- Where
- 2 sites in Honduras, Puerto Rico
- Volunteers
- 91 people
- Sponsor
- Vanderbilt-Ingram Cancer Center
Neoplasm, Stomach, H. Pylori Infection
Early Detection and Screening Strategy of Gatric Cancer in Sichuan Province-A Prospective Cohort Study (WCH-GC-SIGES-01)
To establish prospective cohort of healthy population and corresponding serum sample bank in Sichuan province to provide platform for exploring early diagnosis and screening strategy of gastric cancer by a prospective cohort…
- Conditions
- Neoplasm, Stomach, H. Pylori Infection, Chronic Atrophic Gastritis
- Trial name
- SIGES-01 (NCT03597672)
- Where
- China
- Volunteers
- 30,000 people, healthy volunteers welcome
- Sponsor
- Jian-Kun Hu
Chronic Erosive Gastritis
A Study to Evaluate the Efficacy of Teprenone On Chinese Patients With Chronic Non-Atrophic Erosive Gastritis
The purpose of this study is to evaluate the efficacy of teprenone on chronic non-atrophic erosive gastritis and its therapeutic mechanism
- Trial name
- NCT01284647
- Where
- 8 sites in China
- Volunteers
- 156 people
- Sponsor
- Changhai Hospital
Chronic Atrophic Gastritis, Depressive Symptoms
Objective Vascular Biomarkers as Triage for Depression in Chronic Atrophic Gastritis
Depressive symptoms are highly prevalent in patients with chronic atrophic gastritis (CAG) but are frequently under-detected due to stigma and reliance on subjective questionnaires.
- Conditions
- Chronic Atrophic Gastritis, Depressive Symptoms, Depression, Gastrointestinal Diseases
- Trial name
- NCT07319338
- Testing
- Vascular-Psychological Triage Workflow
- Where
- 4 sites in China
- Volunteers
- 520 people
- Sponsor
- China Academy of Chinese Medical Sciences
Gastritis, Helicobacter Pylori Associated Gastritis
New Technology to Differentiate Normal Gastric Mucosa From Helicobacter Pylori Associated Gastritis and Gastric Atrophy
Endoscopy is a tool that has greatly influenced gastroenterological diagnosis. However, conventional endoscopy is limited to detecting lesions on the basis of gross morphological changes and therefore a certainly diagnosis…
- Conditions
- Gastritis, Helicobacter Pylori Associated Gastritis, Atrophic Gastritis
- Trial name
- NCT02597517
- Testing
- Digital chromoendoscopy and magnification
- Where
- Ecuador
- Volunteers
- 72 people
- Sponsor
- Instituto Ecuatoriano de Enfermedades Digestivas
Gastric Microbiota, Non-atrophic Gastritis
Difference of Gastric Microbiota in the Process of Correa's Model.
Helicobater pylori plays an important role in the development of gastric cancer. Eradication therapy can reducing the morbidity of gastric cancer, but can't totally prevent it especially when atrophy and more serious precancerous…
- Conditions
- Gastric Microbiota, Non-atrophic Gastritis, Atrophic Gastritis, Intestinal Metaplasia
- Trial name
- NCT02833363
- Where
- China
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Shandong University
Tuberculosis, Gastric Cancer
Volatiles in Breath and Headspace Analysis - Diagnostic Markers
Detection of Volatile Organic Compounds (VOC) directly from tissue by headspace analysis (skin, surgery material, other tissue) and exhaled breath is feasible using affordable user-friendly novel nano-chemo sensors that can…
- Conditions
- Tuberculosis, Gastric Cancer, Peptic Ulcer, Atrophic Gastritis
- Trial name
- Volatolome (NCT03228095)
- Testing
- VOC detection in breath and in skin headspace, Breath sampling, Upper endoscopy with biopsies
- Where
- Latvia
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- University of Latvia
Atrophic Gastritis With Low-grade Intraepithelial Neoplasia
Fuzheng Nizeng Formula for Chronic Atrophic Gastritis With Low-grade Intraepithelial Neoplasia, a Multicenter Randomized Controlled Trial
Fuzheng Nizeng Formula (FZNZ) is derived from the classic formula Liujunzi Decoction. Former pilot study found that FZNZ promoted the recovery of gastric atrophy and relieve the relative symptoms.
- Trial name
- NCT06324825
- Testing
- Fuzhegn Nizeng Decoction, Moluodan granules
- Where
- China
- Volunteers
- 144 people
- Sponsor
- Peking University First Hospital
Chronic Atrophic Gastritis (CAG)
Correlation Among Various OLGA and OLGIM Stages, Digestive Symptom Scores, and Acupuncture Treatment in Patients with Chronic Atrophic Gastritis
Brief Summary Template for the Study: The goal of this observational study is to examine the relationship between digestive symptom scores, serum pepsinogen indices, and histopathological OLGA and OLGIM systematic staging of the…
- Trial name
- NCT06707701
- Testing
- acupuncture
- Where
- China
- Volunteers
- 400 people
- Sponsor
- Yi Liang
Chronic Atrophic Gastritis With Hyperplasia (Diagnosis)
Compound Granules of Hedyotis Diffusa for Chronic Atrophic Gastritis
Chronic atrophic gastritis is considered a premalignant lesion of gastric cancer. The development of gastric cancer usually follows the Correa sequence: chronic superficial gastritis → chronic atrophic gastritis → intestinal…
- Trial name
- NCT07391800
- Testing
- Compound Granules of Hedyotis diffusa
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine
Flow Determination
Real-time Observation of Microcirculatory Hemodynamics in Gastric Intestinal Metaplasia by Confocal Laser Endomicroscopy
The morphologic change of microvessels has the clinical value to distinguish cancerous from non-cancerous mucosa. The aim of this study was to observe gastric mucosa microcirculatory hemodynamic changes real-time using pCLE…
- Trial name
- NCT02595151
- Testing
- CLE
- Where
- China
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Shandong University
Chronic Atrophic Gastritis, Hypergastrinaemia
YF476 and Type I Gastric Carcinoids
The aim of the study is to find out if the experimental medicine, YF476, can make gastric carcinoids, a rare type of stomach tumour, shrink and disappear.
- Conditions
- Chronic Atrophic Gastritis, Hypergastrinaemia, Type I Gastric Carcinoids
- Trial name
- NCT01339169
- Testing
- YF476
- Where
- United Kingdom
- Volunteers
- 8 people
- Sponsor
- Trio Medicines Ltd.