Clinical trials: Chronic Brain Injury
Cerebral Palsy
Virtual Reality versusTask-oriented for Gait in CP
The children with hemiplegic cerebral palsy had a longer gait cycle, slower walking speed, and longer support phase than did the healthy children.
- Trial name
- NCT04533789
- Testing
- selected physical therapy program
- Where
- Egypt
- Volunteers
- 45 people
- Sponsor
- South Valley University
Cerebral Palsy (CP), Balance Assessment
Combined Effect of FES And FCT in Cerebral Palsy
To determine the combined effect of functional electrical stimulation and functional circuit training on postural stability, balance, and functional mobility in cerebral palsy
- Trial name
- NCT07573891
- Testing
- Functional Electrical Stimulation and Functional Circuit Training, Control Group
- Where
- Pakistan
- Volunteers
- 46 people
- Sponsor
- Riphah International University
Chronic Subdural Hematoma, Subdural Drain
The Effect of Subdural Drain Placement After Burr Hole Evacuation of Chronic Subdural Haematomas on Recurrence: a Prospective Randomised-controlled Multi-centre Study
This is a prospective randomised-controlled multi-centre trial based in Hong Kong to determine whether temporary subdural drain placement after burr hole evacuation of a chronic subdural haematoma can reduce the risk of…
- Trial name
- NCT01785797
- Testing
- Silicon subdural drain placement after burr hole evacuation of chronic subdural hematoma
- Where
- China
- Volunteers
- 260 people
- Sponsor
- Kwong Wah Hospital
Chronic Subdural Hematoma
The Efficacy of the Longeviti ClearFit Implant in Craniectomies for Post-Operative Monitoring in Chronic Subdural Hematomas
Chronic subdural hematomas are frequent neurosurgical issues that are most often treated with burr hole craniectomies to drain the subdural fluid.
- Trial name
- NCT06127615
- Testing
- ClearFit
- Sponsor
- University of Kansas Medical Center
Cerebral Palsy (CP)
Constraint-induced Movement Therapy Combined With Functional Electrical Stimulation in Children With Cerebral Palsy
This randomized controlled trial aims to compare the effectiveness of Constraint-Induced Movement Therapy (CIMT) combined with Functional Electrical Stimulation (FES) versus CIMT alone in improving upper limb function, reducing…
- Trial name
- CIMT-FES-CP (NCT07587476)
- Testing
- Constraint-Induced Movement Therapy Combined with Functional Electrical Stimulation, Constraint-Induced Movement Therapy
- Where
- Pakistan
- Volunteers
- 46 people
- Sponsor
- Montiha Azeem
Cerebral Palsy
Cerebral Palsy Hip Outcomes Project - International Multi-centre Study
The primary purpose of the project is to evaluate the effectiveness of different intervention strategies to prevent or relieve symptoms associated with hip instability in children with severe cerebral palsy, using the validated…
- Trial name
- NCT01987882
- Where
- 27 sites in United States, Australia and 8 more
- Volunteers
- 500 people
- Sponsor
- Holland Bloorview Kids Rehabilitation Hospital
Cerebral Palsy, Poststroke/CVA Paresis
The Middle East "Stepping Forward" Project (MESF)
The overall objective is to improve the functional status of Middle East adolescents with disabilities due to cerebral palsy (CP) and disabilities in adults due to cerebro-vascular stroke (Hemiplegia) by a collaborative…
- Trial name
- MESF (NCT01466296)
- Testing
- Chaotic Perturbation, Dummy not active shoes, Treadmill training
- Where
- Israel
- Volunteers
- 120 people
- Sponsor
- Assaf-Harofeh Medical Center
Spastic Diplegic Cerebral Palsy
Strength Training Using Neuromuscular Electrical Stimulation For Children With Cerebral Palsy
The purpose of this study is to determine if using high-intensity, short-duration, intermittent neuromuscular electrical stimulation (NMES) is better than volitional exercise in increasing quadriceps femoris and triceps surae…
- Trial name
- NCT00356343
- Testing
- NMES Strength Training, Volitional Strength Training
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Hypotonia, Muscle, Obstructive Sleep Apnea
Long-term Evaluation of Nasopharyngeal Airway in Hypotonia
This research is studying the long term use of a nasal airway device (self-supporting nasopharyngeal airway; "ssNPA") in children with hypotonic upper airway obstruction to learn about its effectiveness and tolerability as a…
- Conditions
- Hypotonia, Muscle, Obstructive Sleep Apnea, Nasal Airway Obstruction
- Trial name
- NCT06614582
- Testing
- Self-Supporting Nasopharyngeal Airway (ssNPA)
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Michigan
Cerebral Palsy
The Effects of Hand-Arm Bimanual Intensive Training (HABIT) in Children With Bilateral Cerebral Palsy
Hand-Arm Bimanual Intensive Training (HABIT) has been shown to result in improvements in hand function and daily functioning of children with unilateral cerebral palsy (CP).
- Trial name
- NCT03474848
- Testing
- HABIT, Conventional Occupational Therapy (OT)
- Volunteers
- 40 people
- Sponsor
- Federal University of Minas Gerais
Cerebral Palsy
Motor Learning in People With Cerebral Palsy by Using Virtual Reality.
Cerebral Palsy (CP) is a group of permanent disorders that affect movement and posture due to a non-progressive lesion in the immature brain occurring in fetal brain development or in infancy.
- Trial name
- NCT03348943
- Testing
- Right hemiparesis, right upper limb., Right hemiparesis, left upper limb, Left hemiparesis, left upper limb
- Where
- Brazil
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Spinal Cord Injuries, Spina Bifida
Examining Capacity Building of Youth With Physical Disabilities to Pursue Participation Following the PREP Intervention.
The goal of this clinical trial is to learn about how a participation-based intervention builds capacity of youth with physical disabilities to pursue activities of their choice in the community.
- Conditions
- Spinal Cord Injuries, Spina Bifida, Musculoskeletal Disorder, Juvenile Arthritis
- Trial name
- NCT06007885
- Testing
- Pathways and Resources to Engagement and Participation (PREP)
- Where
- Canada
- Volunteers
- 10 people
- Sponsor
- McGill University
Cerebral Palsy
Supported Speed Treadmill Training Exercise Program (SSTTEP) for Marginally Ambulatory Children With Cerebral Palsy
The investigators are studying the effects of a 12-week exercise program, consisting of either: 1. Walking on a treadmill with partial body weight 2.
- Trial name
- SSTTEP (NCT00467415)
- Testing
- Partial body weight support treadmill training, Exercise
- Where
- 3 sites in United States
- Volunteers
- 66 people
- Sponsor
- Shriners Hospitals for Children
Cognition Disorder, Attention Deficit Disorder
Dopamine Receptor Imaging to Predict Response to Stimulant Therapy in Chronic TBI
Deficits in memory, attention, cognitive, and executive functions are the most common disabilities after traumatic brain injury (TBI).
- Conditions
- Cognition Disorder, Attention Deficit Disorder, Traumatic Brain Injury
- Trial name
- DAPET-TBI (NCT02225106)
- Testing
- Methylphenidate
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- University of Pennsylvania
Traumatic Brain Injury
Self-Management Training Among Individuals With TBI
Traumatic brain injury (TBI) can have long-term and chronic effects on an individual's physical, social, and emotional health, impacting quality of life and the ability to engage in meaningful life roles.
- Trial name
- NCT07741149
- Testing
- Participants will be referred to a community based self-management training program
- Volunteers
- 85 people
- Sponsor
- Boston University Charles River Campus
Concussion, Brain, Concussion, Mild
Mobile Subthreshold Exercise Program for Concussion--R01
Approximately 1.9 million youth sustain a concussion each year, and up to 30% experience persistent post-concussive symptoms (PPCS) such as headache, dizziness, and difficulty focusing that continue for weeks or months.
- Conditions
- Concussion, Brain, Concussion, Mild, Brain Injuries, Traumatic, Persistent Post Traumatic Headache
- Trial name
- MSTEP-R01 (NCT04688255)
- Testing
- MSTEP, Stretching
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Seattle Children's Hospital
Cerebral Palsy, Perinatal Stroke
Home-based Early Intensive Hemiparesis Therapy: Engaging Nurture
The purpose of the study is to assess implementation and effectiveness of a caregiver-delivered rehabilitation intervention for infants and toddlers with cerebral palsy.
- Trial name
- HEIGHTEN (NCT05346887)
- Testing
- Home-based Therapy
- Where
- 2 sites in Canada
- Volunteers
- 20 people
- Sponsor
- University of Calgary
Chronic Stroke, Cerebral Palsy
Gondola Mechanism of Action
This study will investigate the clinical, functional and neurophysiological effects of automated mechanical peripheral stimulation (AMPS) via the Gondola device administered to patients with chronic stroke, cerebral palsy and…
- Conditions
- Chronic Stroke, Cerebral Palsy, Parkinson's Disease
- Trial name
- NCT05146648
- Testing
- Gondola AMPS
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Cerebral Palsy
Treatment of Children With Cerebral Palsy With Autologous Umbilical Cord Blood, a Pilot Study
This study is a phase II, prospective, double blind, placebo-controlled study of the efficacy of autologous umbilical cord blood infusion.
- Trial name
- NCT04243408
- Testing
- Autologous umbilical cord blood transfusion
- Where
- Israel
- Volunteers
- 72 people
- Sponsor
- Sheba Medical Center
Subdural Hematoma
MMA Embolization With NeoCast for Subacute and Chronic Subdural Hematoma
The purpose of this study is to evaluate the safety and efficacy of embolization of the middle meningeal artery (MMA) using the NeoCast Embolic System for treatment of symptomatic subacute or chronic subdural hematoma (SDH)…
- Trial name
- RADIANT (NCT07541404)
- Testing
- NeoCast Embolic System, Onyx LES, an FDA-Approved Commercial Liquid Embolic
- Where
- 2 sites in United States
- Volunteers
- 360 people
- Sponsor
- Arsenal Medical, Inc.