Clinical trials: Chronic Cerebral Ischemia
Stroke
Ischemic Conditioning Chronic Stroke Study
Stroke is the leading cause of disability in adults in the United States. Despite advances in hyperacute stroke care, advancements in stroke rehabilitation are lagging.
- Trial name
- NCT04039399
- Testing
- Ischemic Conditioning
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Medical College of Wisconsin
Stroke, Ischemic Stroke
Myosuit Chronic Stroke Protocol
A stroke is a vascular condition that can suddenly cause the loss of neurological functions. The disability derived from a stroke can imply reduced communication and limited activities of daily living in the long term.
- Conditions
- Stroke, Ischemic Stroke, Haemorrhagic Stroke
- Trial name
- MyoSCSP (NCT05579197)
- Testing
- Lower-limb robotic intervention
- Where
- Italy
- Volunteers
- 10 people
- Sponsor
- Fondazione Don Carlo Gnocchi ETS
Chronic Cerebral Ischemia
Study on Efficacy and Safety of Divaza in Patients With Chronic Cerebral Ischemia and Cognitive Disorders
An open-label, prospective, observational, multicenter study. The study enrolls adult outpatients with CCI from 8 federal districts of the Russian Federation.
- Trial name
- DIAMANT (NCT04370028)
- Testing
- Divaza
- Volunteers
- 2,583 people
- Sponsor
- Materia Medica Holding
Stroke, Chronic Stroke Patients
kTMP-Enhanced Motor Rehabilitation for Chronic Stroke Recovery (KULMINATE) Pilot
kTMP, kilohertz transcutaneous magnetic perturbations, is a low intensity transcranial magnetic stimulation technique that will be used in this study to promote arm/hand rehabilitation in patients who have been disabled by stroke.
- Conditions
- Stroke, Chronic Stroke Patients, Arm Weakness as a Consequence of Stroke
- Trial name
- NCT07631078
- Testing
- kTMP
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Magnetic Tides
Stroke, Ischemic, Ambulation Disorder, Neurologic
Blood Flow Restricted High-Intensity Treadmill Training on Independently Ambulating Chronic Ischemic CVA Survivors
Individuals surviving Chronic Ischemic Stroke have lingering walking deficits long after their infarct. The main goal of this study is to compare two high intensity treadmill walking programs to see which improves walking more.
- Conditions
- Stroke, Ischemic, Ambulation Disorder, Neurologic, Chronic Stroke
- Trial name
- NCT06214494
- Testing
- Blood Flow Restricted High Intensity Treadmill Training, HITT
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- MedStar National Rehabilitation Network
Ischaemic Stroke, Hemorrhagic Stroke
Exploratory Study on the Potential Cross-System Effects of BCI-FES Hand Therapy on Dysphagia and Aphasia in Chronic Stroke Patients
The goal of this neurorehabilitation explorative study is to investigate how a closed-loop Brain-Computer Interface Functional Electrical Stimulation (BCI-FES) therapy, used within the intended purpose for hand rehabilitation…
- Trial name
- c-STEPS (NCT06940635)
- Testing
- closed-loop BCI-FES device
- Where
- Austria
- Volunteers
- 10 people
- Sponsor
- VASCage GmbH
Chronic Venous Insufficiency, Peripheral Arterial Disease
Outpatient Office Based Endovascular Procedures
The results of this study will serve as a starting point for future trials concentrating on the effectiveness and clinical outcomes of the procedures performed in an office based angiosuite.
- Conditions
- Chronic Venous Insufficiency, Peripheral Arterial Disease, Dialysis Access Malfunction, Arterio-venous Fistula
- Trial name
- NCT04054440
- Where
- United States
- Volunteers
- 26,000 people
- Sponsor
- Methodist Health System
Stroke
WAveCrest Vs. Watchman TranssEptal LAA Closure to REduce AF-Mediated STroke 2
The WAVECREST 2 trial is a prospective, multicenter, randomized, active controlled, clinical trial to evaluate the safety and effectiveness of the Coherex WaveCrest Left Atrial Appendage (LAA) Occlusion System.
- Trial name
- WAVECREST2 (NCT03302494)
- Testing
- Coherex WaveCrest® Left Atrial Appendage Occlusion System, Watchman® LAA Closure Device
- Where
- 25 sites in United States, Australia
- Volunteers
- 248 people
- Sponsor
- Coherex Medical
Coronary Disease, Myocardial Infarction
Chronical Illness-related Limitations of the Ability to Cope with Rising Temperatures: an Observational Study, 2nd Wave
The CLIMATE-II Observational Study examines to what extent chronically ill patients experience adverse health effects because of heat and whether the patients' specific health behavior, somatosensory amplification, risk and…
- Conditions
- Coronary Disease, Myocardial Infarction, Heart Failure, Arrhythmias, Cardiac
- Trial name
- CLIMATE-II (NCT06407154)
- Where
- Germany
- Volunteers
- 578 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Ischemic Stroke
Effects of Intravascular Laser Irradiation of Blood for Mitochondral Dysfunction in Cerebral Ischemic Stroke
Background : This research is designed through randomization, control, and double-blind trial to explore the clinical effectiveness of intravenous laser irradiation of blood for ischemic stroke patient; The research will further…
- Trial name
- NCT06932627
- Testing
- ILIB
- Where
- Taiwan
- Volunteers
- 8 people
- Sponsor
- Tri-Service General Hospital (TSGH)
Stroke Sequelae, Brain Ischemia
EEG Based BCI for Upper Limb Rehabilitation in Stroke
Biomedical and Engineering approaches form a key element to neurological rehabilitation of upper limbs. Brain Computer Interface (BCI) using Motor execution and Motor Imagery are known to aid motor recovery in stroke.
- Trial name
- NCT04188132
- Testing
- EEG -BCI based Feedback for rehabilitation
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of Houston
Coronary Disease, Cardiovascular Diseases
Cardiac and Renal Disease Study (CARDS)
To examine the epidemiology of renal disease and its relationship to cardiovascular disease.
- Conditions
- Coronary Disease, Cardiovascular Diseases, Cerebrovascular Accident, Heart Failure
- Trial name
- NCT00049907
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Cerebral Stroke
Can we Train Patients With Chronic Stroke Out of Abnormal Hand Synergy?
This study plans to determine whether training can change abnormal flexion synergy in chronic stroke patients.
- Trial name
- NCT03255590
- Testing
- Configuration task
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Johns Hopkins University
Silent Stroke, Coronary Disease
Evaluation of Brain Damage Due to Coronary Angioplasty in Percutaneous Intervention Patients
This study examines the formation mechanism and patient-related factors of silent cerebral infarcts, whose importance has become increasingly recognized in patients undergoing percutaneous coronary intervention.
- Trial name
- NCT04734587
- Testing
- Blood serum Neuron-specific Enolase measurement
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Ondokuz Mayıs University
Stroke, Middle Cerebral Artery Infarction
Efficacy Study of CD34 Stem Cell in Chronic Stroke Patients
The objective of the study is to determine the efficacy of brain transplants of CD34+ stem cells obtained from peripheral blood of patients in the treatment of chronic stroke patients.
- Trial name
- NCT00950521
- Testing
- Intercerebral implantation of Autulogous Stem Cells, convention therapy
- Where
- Taiwan
- Volunteers
- 30 people
- Sponsor
- China Medical University Hospital
Atrial Fibrillation, Coronary Heart Disease
EMPOWER-1: A Multi-site Clinical Cohort Research Study to Reduce Health Inequality
Health inequality and genetic disparity are a significant issue in the United Kingdom (UK). This study focuses on diseases that are associated with significant morbidity and mortality in the UK, and specifically examines the…
- Conditions
- Atrial Fibrillation, Coronary Heart Disease, Cardiovascular Diseases, Heart Failure
- Trial name
- EMPOWER (NCT03987633)
- Where
- United Kingdom
- Volunteers
- 200,000 people, healthy volunteers welcome
- Sponsor
- Future Genetics Limited
Alzheimer Disease, Alzheimer Dementia
Alzheimer's Autism and Cognitive Impairment Stem Cell Treatment Study
The purpose of the study is to evaluate the use of autologous Bone Marrow Derived Stem Cells (BMSC) as a means to improve cognitive impairment as occurs in Alzheimer's Disease and other dementias and to improve behavior and…
- Conditions
- Alzheimer Disease, Alzheimer Dementia, Vascular Dementia, Lewy Body Disease
- Trial name
- ACIST (NCT03724136)
- Testing
- Intravenous Bone Marrow Stem Cell (BMSC) Fraction, Intranasal Topical Bone Marrow Stem Cell (BMSC) Fraction, Near Infrared Light
- Where
- 3 sites in United States, United Arab Emirates
- Volunteers
- 100 people
- Sponsor
- MD Stem Cells
Stroke, Chronic Stroke
Wireless Nerve Stimulation Device To Enhance Recovery After Stroke
Texas Biomedical Device Center (TxBDC) has developed an innovative strategy to enhance recovery of motor and sensory function after neurological injury termed targeted plasticity therapy (TPT).
- Conditions
- Stroke, Chronic Stroke, Upper Extremity Paresis, Ischemic Stroke
- Trial name
- NCT04534556
- Testing
- Active Vagus Nerve Stimulation
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- Baylor Research Institute
Stroke, Stroke, Ischemic
Intracerebral Autologous Stem Cell Therapy for Chronic Stroke Patients
The goal of this clinical trial is to evaluate if autologous mesenchymal stem cell (HUNS001-01) transplantation therapy can provide neurological recovery in patients with chronic stage of stroke resulting in moderate to severe…
- Conditions
- Stroke, Stroke, Ischemic, Stroke; Sequelae
- Trial name
- RAINBOW-2a (NCT06752720)
- Testing
- Stem cell Transplantation
- Where
- Japan
- Volunteers
- 8 people
- Sponsor
- Hokkaido University Hospital
Chronic Stable Angina, Unstable Angina
The Role of Alcohol Consumption in the Aetiology of Different Cardiovascular Disease Phenotypes: a CALIBER Study
The association between alcohol consumption and cardiovascular disease (CVD) has mostly been examined using broad endpoints or cause-specific mortality.
- Conditions
- Chronic Stable Angina, Unstable Angina, Coronary Heart Disease Not Otherwise Specified, Acute Myocardial Infarction
- Trial name
- NCT01864031
- Where
- United Kingdom
- Volunteers
- 2,240,000 people
- Sponsor
- University College, London