Clinical trials: Chronic Constipation
- Condition Chronic Constipation
- Funder type Industry (pharma, biotech, devices)
- Accepts healthy volunteers yes
Chronic Constipation
Effects of Oral PEG 3350 on Electrolyte Balance
The study is to evaluate the influence of three different doses of PEG 3350 with or without electrolytes on the electrolyte balance in patient volunteers with confirmed chronic constipation.
- Trial name
- NCT00868985
- Testing
- PEG 3350 plus electrolytes, PEG 3350 without electrolytes
- Where
- Romania
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- Norgine
Constipation
Efficacy and Tolerability of Cassia Fistula Plus Senna Alexandrina Miller (Sugar Free) in the Chronic Functional Constipation (CFC).
Primary Objective: To evaluate the clinical efficacy of Naturetti (jelly sugar free) To test medication on subjects who suffer chronic functional constipation in 30 days use.
- Trial name
- NCT00931853
- Testing
- SENNA+CASSIA(Naturetti)
- Where
- Brazil
- Volunteers
- 117 people, healthy volunteers welcome
- Sponsor
- Sanofi
Constipation and Dyspepsia
The Effects of Tegaserod vs. Placebo on Whole Gut Transit Time in Patients With Chronic Constipation and Dyspepsia
To demonstrate the effects of tegaserod on gastrointestinal scintigraphic orocecal transit in female patients with CC and upper GI symptoms of dyspepsia
- Trial name
- NCT00277550
- Volunteers
- healthy volunteers welcome
- Sponsor
- Novartis
Chronic Constipation, Constipation
Safety and Efficacy of Linaclotide in Patients With Chronic Constipation and Prominent Abdominal Bloating
The purpose of this study is to evaluate the efficacy and safety of linaclotide compared with placebo in patients with chronic constipation (CC) and prominent abdominal bloating.
- Trial name
- NCT01642914
- Testing
- Linaclotide 290 micrograms, Linaclotide 145 micrograms
- Where
- 151 sites in United States, Canada
- Volunteers
- 487 people, healthy volunteers welcome
- Sponsor
- Forest Laboratories
Chronic Constipation
Exploring the Potential Benefits of Probiotic Yogurt
This study aims to evaluate the effect of a high-activity probiotic yogurt on improving symptoms of chronic constipation, observing its regulatory effects on the gut microbiota and the incidence of adverse reactions in study…
- Trial name
- NCT06847919
- Testing
- Probiotic yogurt group, Yogurt control group
- Where
- China
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Wecare Probiotics Co., Ltd.
Infrequent Bowel Movements
Investigation of the Effects of a Bifidobacterial Strain on Bowel Movement in Healthy Adults
The goal of this clinical trial is to investigate whether a supplement containing the B. longum strain works to alleviate constipation in adults. The main questions it aims to answer are: Does a supplement containing the B.
- Trial name
- NCT06686420
- Testing
- B. longum
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Morinaga Milk Industry Co., LTD
Constipation
Double-Blind, Double-Dummy, 2-Period Crossover of a 20-Minute Versus a 4-hour IV of MOA-728 in Stable Methadone Subjects
MOA-728, an investigational drug, is currently being studied for the relief of constipation associated with postoperative ileus and treatment of opioid induced constipation in patients receiving palliative care.
- Trial name
- NCT00444158
- Testing
- MOA-728
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Bausch Health Americas, Inc.
Constipation
A Study to Evaluate the Effects of a Natural Supplement in Adults With Chronic Functional Constipation
Constipation is common in the general population, especially in women and in the elderly. Hard stool is a complaint often associated with constipation, which suggests that stool softening would provide a major benefit in the…
- Trial name
- NCT02073006
- Testing
- Natural Fibre Supplement
- Where
- Ireland
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Atlantia Food Clinical Trials
Chronic Idiopathic Constipation
This Study Aims to Evaluate the Safety, Tolerability, Pharmacokinetic and Pharmacodynamic Properties and Food Effect of IN-114199 in Healthy Participants
This study aims to evaluate the safety, tolerability, pharmacokinetic and pharmacodynamic properties and food effect of IN-114199 in healthy participants
- Trial name
- NCT06736912
- Where
- South Korea
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- HK inno.N Corporation
Chronic Constipation
Effectiveness and Safety of Probiotic in Regulating Chronic Constipation
To evaluate the effectiveness and safety of the use of probiotics as food supplements in regulating the intestinal habit of subjects with chronic constipation, in comparison with placebo.
- Trial name
- NCT05980988
- Testing
- Probiotic
- Where
- 2 sites in Spain
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Wecare Probiotics Co., Ltd.
Con, Cons ti
Probiotic for Alleviating Functional Constipation in Adults
To investigate the clinical effects of probiotics in relieving chronic constipation in adults, and evaluate the improvement of symptoms in patients with constipation as well as their impacts on gastrointestinal function and gut…
- Conditions
- Con, Cons ti, Con s ti
- Trial name
- NCT07649564
- Testing
- Probiotic
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Wecare Probiotics Co., Ltd.
Constipation
Probiotics for Alleviating Chronic Constipation in Adults
To investigate the clinical effects of probiotics in relieving intestinal motility and chronic constipation through regulating gut microbiota.
- Trial name
- NCT07152795
- Testing
- Probiotic
- Where
- China
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Wecare Probiotics Co., Ltd.